Funding Clinical Trials

Our Agency funds clinical trials testing promising stem cell or gene therapies for currently incurable diseases or disorders to help patients with unmet medical needs. For basic information about stem cell trials, visit our Clinical Trials 101 page. For a list of clinical trials that are a result of early-stage CIRM grants click here.

106

CIRM-FUNDED CLINICAL TRIALS

Disease AreasInvestigatorOrganizationPhaseTrial StatusTarget EnrollmentDetail
Neurological Disorders Amit Etkin Alto Neuroscience Phase 2 Launching N/A
Blood Cancer Dr. Edward Kavalerchik Angiocrine Bioscience, Inc. Phase 1 Completed 10
Blood Cancer Dr. Edward Kavalerchik Angiocrine Bioscience, Inc. Phase 1/2 Completed 42
B cell cancers Dr. Paul Finnegan Angiocrine Bioscience, Inc. Phase 3 Closed 130
Parkinson's Disease Dr. Edward Wirth III Aspen Neuroscience Phase 1 Launching N/A
Solid Tumors Dr. Pamela Reilly Contag BioEclipse Therapeutics INC. Phase 1 Recruiting 60
Sickle Cell Disease David Williams Boston Children’s Hospital Phase 2 Recruiting 25
Parkinson's Disease Krystof S. Bankiewicz Brain Neurotherapy Bio Phase 1 Active, not recruiting 11
Amyotrophic Lateral Sclerosis Dr. Ralph Kern BrainStorm Cell Therapeutics Phase 3 Completed 196
Melanoma Robert Dillman Caladrius Biosciences Phase 3 Closed 4
Type 1 diabetes Dr. William Sietsema Caladrius Biosciences Phase 2 Completed 113
Arthritis
Osteoarthritis		 Dr. Kristen A Johnson Calibr Phase 1 Completed 60
HIV/AIDS Geoff Symonds Calimmune, Inc. Phase 1/2 Completed 13
Heart failure Dr. Rachel Ruckdeschel Smith Capricor, Inc Phase 2 Closed 135
Heart disease associated with Duchenne muscular dystrophy Dr. Linda Marban Capricor, Inc Phase 2 Completed 25
Amyotrophic Lateral Sclerosis Professor Clive Niels Svendsen Cedars-Sinai Medical Center Phase 1/2 Completed 18
Pulmonary Hypertension
Vascular Disease		 Dr. Michael I Lewis Cedars-Sinai Medical Center Phase 1/2 Completed 26
Retinitis Pigmentosa Clive Svendsen Cedars-Sinai Medical Center Phase 1 Recruiting 16
Amyotrophic Lateral Sclerosis Clive Svendsen Cedars-Sinai Medical Center Phase 1 Launching N/A
COVID-19
Respiratory Disorders		 William van der Touw Celularity Inc. Phase 1/2 Active, not recruiting 86
Blood Cancer
Bone Marrow Transplant and Viral Infection		 Michael A. Pulsipher Children’s Hospital of Los Angeles Phase 1/2 Active, not recruiting 60
Brain Cancer Dr. Christine E. Brown City of Hope, Beckman Research Institute Phase 1 Active, not recruiting 82
HIV/AIDS Prof. John A Zaia City of Hope, Beckman Research Institute Phase 1 Active, not recruiting 12
Sickle Cell Disease Dr. De-Fu Zeng City of Hope, Beckman Research Institute Phase 1 Active, not recruiting 3
Brain Cancer
Breast Cancer		 Dr Saul J Priceman City of Hope, Beckman Research Institute Phase 1 Recruiting 39
COVID-19
Respiratory Disorders		 Prof. John A Zaia City of Hope, Beckman Research Institute Phase 1 Launching N/A
Brain Cancer Dr. Leo D Wang City of Hope, Beckman Research Institute Phase 1 Recruiting 18
Brain Cancer Dr Jana Portnow City of Hope, Beckman Research Institute Phase 1 Launching N/A
Anemia Ryotaro Nakamura City of Hope, Beckman Research Institute Phase 1 Launching N/A
HIV/AIDS Dr. Angelo Manuel Almeida Cardoso Ph.D., MD City of Hope, Beckman Research Institute Phase 1 Launching N/A
Leukemia, Acute Myeloid (AML) Elizabeth Budde City of Hope, Beckman Research Institute Phase 1 Launching N/A
Corneal Damage R. Kim Brazzell Combangio, Inc. Phase 2 Launching N/A
Solid Tumors Pei Wang Eureka Therapeutics, Inc. Phase 1/2 Launching N/A
Sickle Cell Disease Dr Pierre Caudrelier ExCellThera Inc. Phase 1 Withdrawn N/A
HIV/AIDS William Kennedy Excision BioTherapeutics Phase 1 Recruiting 9
Lupus, Systemic Lupus Erythematosus (SLE) Barbara Hickingbottom Fate Therapeutics, Inc. Phase 1 Launching N/A
Leukemia, Acute Myeloid (AML) Mark Chao Forty Seven Inc. Phase 1 Closed 258
Colon Cancer Mark Chao Forty Seven Inc. Phase 1/2 Completed 78
Osteoarthritis Dr. Thomas W Chalberg Jr. Genascence Corporation Phase 1 Launching N/A
Spinal Cord Injury Dr. Jane Stephanie Lebkowski Dr. Geron Corporation Phase 1 Completed 5
Kidney Failure Jeffrey Lawson Humacyte, Inc. Phase 3 Active, not recruiting 240
Kidney Failure Jeffrey Lawson Humacyte, Inc. Phase 3 Completed 355
Immune Disease DR Jonathan Benjamin ImmPACT-Bio, Inc. Phase 1/2 Launching N/A
Leukemia, Acute Myeloid (AML) Joseph Paul Woodard Immune-Onc Therapeutics Phase 1 Recruiting 106
Brain Cancer Anthony J. Gringeri ImmunoCellular Therapeutics Phase 3 Suspended 234
Bone or Cartilage Disease
Hearing Loss
Intellectual Disability
Metabolic Disorders
Vision Loss		 Dr Robert Hayes Immusoft Corporation Phase 1 Launching N/A
Immune Disease
Pediatrics
Severe Combined Immunodeficiency, X-linked (X-SCID)		 Dr. Judith A Shizuru
Wendy Pang		 Stanford University
Jasper Therapeutics, Inc.		 Phase 1/2 Recruiting 40
Retinitis Pigmentosa Henry John Klassen jCyte, Inc Phase 2 Completed 84
Retinitis Pigmentosa Henry John Klassen jCyte, Inc Phase 2 Completed 84
Spinal Cord Injury Francois Binette Lineage Cell Therapeutics, Inc. Phase 1/2 Completed 25
Kidney Failure Daniel Brennan Medeor Therapeutics, Inc. Phase 3 Active, not recruiting 30
Epilepsy Dr. Cory R Nicholas Neurona Therapeutics Phase 1 Recruiting 40
Leukemia, Acute Myeloid (AML) Dr. Colleen Delaney Nohla Therapeutics Inc Phase 2 Closed 146
Genetic Disorder
Immune Disease
Pediatrics
Severe Combined Immunodeficiency, Adenosine deaminase-deficient (ADA-SCID)		 Dr. Donald B Kohn
Leslie Meltzer
Dr. Donald B. Kohn		 University of California, Los Angeles
Orchard Therapeutics plc		 Phase 2 Completed 10
Multiple Myeloma Rajesh Belani MD Poseida Therapeutics, Inc. Phase 1 Closed 105
Age-related macular degeneration Dr Jane S Lebkowski Regenerative Patch Technologies LLC Phase 2 Launching N/A
Immune Disease
Leukocyte Adhesion Deficiency		 Dr. Kinnari Patel Rocket Pharmaceuticals, Inc. Phase 1/2 Completed 9
Bone or Cartilage Disease Dr. Gayatri Rao Rocket Pharmaceuticals, Inc. Phase 1 Closed 1
Stroke Dr. Bijan Nejadnik SanBio, Inc. Phase 2 Completed 163
Beta Thalassemia Bettina Cockroft Sangamo BioSciences, Inc. Phase 1/2 Completed 5
Immune Disease
Severe Combined Immunodeficiency, X-linked (X-SCID)		 Stephen Gottschalk St. Jude Children’s Research Hospital Phase 1/2 Suspended 28
Blood Cancer
Solid Tumors		 Dr. Irving L Weissman MD Stanford University Phase 1 Completed 88
Kidney Failure Dr Robert Lowsky Stanford University Phase 1 Active, not recruiting 15
B cell cancers
Leukemia		 Dr. David B. Miklos Stanford University Phase 1 Active, not recruiting 56
Kidney Failure Dr. Everett H. Meyer Stanford University Phase 1 Recruiting 22
Stroke Dr. Gary Steinberg Stanford University Phase 1 Recruiting 30
Brain Cancer Crystal Mackall Stanford University Phase 1 Recruiting 54
B cell cancers
Leukemia
Leukemia, Acute Myeloid (AML)		 Dr. Matthew H Porteus Stanford University Phase 1 Recruiting 22
Heart failure Dr. Joseph C. Wu Stanford University Phase 1 Recruiting 18
IPEX Syndrome Dr. Rosa Bacchetta Stanford University Phase 1 Recruiting 30
Anemia
Bone Marrow Transplant and Viral Infection		 Alice Bertaina Stanford University Phase 1/2 Launching N/A
Anemia Dr. Matthew H Porteus Stanford University Phase 1/2 Launching N/A
Brain Cancer Dr. Reena Parada Thomas Stanford University Phase 1 Launching N/A
Melanoma Anusha Kalbasi Stanford University Phase 1 Launching N/A
Colon Cancer Ivan King Tachyon Therapeutics, Inc Phase 1 Launching N/A
Huntington's Disease Dr. Vicki Wheelock University of California, Davis Phase 1/2 Completed 29
HIV-related Lymphoma
HIV/AIDS		 Dr Mehrdad Abedi University of California, Davis Phase 1/2 Active, not recruiting 11
Osteonecrosis Nancy E. Lane University of California, Davis Phase 1/2 Completed 58
Developmental Disorders
Spina Bifida		 Dr. Diana L. Farmer University of California, Davis Phase 2 Recruiting 55
Muscle Injury Peter C Belafsky University of California, Davis Phase 1/2 Recruiting 62
Retinitis Pigmentosa Dr. Henry John Klassen University of California, Irvine Phase 1/2 Completed 28
Melanoma
Skin cancer		 Dr. Antoni Ribas M.D., Ph.D. University of California, Los Angeles Phase 1 Closed 5
Immune Disease
Pediatrics
X-linked Chronic Granulomatous Disease		 Dr. Donald B. Kohn University of California, Los Angeles Phase 1/2 Recruiting 16
Pediatrics
Sickle Cell Disease		 Dr. Donald B. Kohn University of California, Los Angeles Phase 1 Recruiting 6
Solid Tumors Dr. Dennis J Slamon University of California, Los Angeles Phase 1 Completed 46
Lung Cancer Steven M. Dubinett University of California, Los Angeles Phase 1 Recruiting 24
Sarcoma Theodore Scott Nowicki University of California, Los Angeles Phase 1 Closed 5
Corneal Damage Dr. Sophie X Deng University of California, Los Angeles Phase 1 Recruiting 20
B cell cancers
Leukemia		 Thomas J Kipps University of California, San Diego Phase 1/2 Active, not recruiting 102
Blood Cancer Thomas J Kipps University of California, San Diego Phase 1 Completed 26
Cystinosis
Kidney Failure		 Dr. Stephanie Cherqui University of California, San Diego Phase 1/2 Active, not recruiting 6
Neurological Disorders
Other		 Prof. Olivia Kim-McManus University of California, San Diego Phase 1/2 Launching N/A
Alpha Thalassemia Major Dr. Tippi C. Mackenzie MD University of California, San Francisco Phase 1 Enrolling by invitation 10
Severe Combined Immunodeficiency, Artemis deficient (ART-SCID) Mort Cowan University of California, San Francisco Phase 1 Recruiting 25
Type 1 diabetes Peter Stock University of California, San Francisco Phase 1/2 Recruiting 8
COVID-19 Dr. Michael Matthay MD University of California, San Francisco Phase 2 Completed 120
HIV/AIDS
Immune Disease		 Steven G. Deeks University of California, San Francisco Phase 1/2 Recruiting 18
Sickle Cell Disease Mark C. Walters M.D. University of California, San Francisco Phase 1 Not yet recruiting 9
Brain Cancer Dr. Hideho Okada University of California, San Francisco Phase 1 Launching N/A
Age-related macular degeneration Dr. Mark S Humayun University of Southern California Phase 1 Unknown status 16
Type 1 diabetes Howard Foyt ViaCyte, Inc. Phase 1/2 Closed 19
Type 1 diabetes Manasi Jaiman ViaCyte, Inc. Phase 1/2 Completed 49
Bladder or Urinary Tract Disorder James Yoo Wake Forest University Health Sciences Phase 1 Not yet recruiting 10
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