City of Hope, Beckman Research Institute

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Total Awards:
55
Award Value:
$205,110,568
Institution type:
Not for profit
Short Name:
COH

Awards to the Institution

Program Type Investigator Grant Title Award Value
Manufacturing Network Grant Dr. Taby Ahsan Scalable Expansion for Stem Cell-derived Therapies $1,998,174
Research Training Grant Dr. Michael E. Barish Ph, D. Research Training Program in Stem Cell Biology and Regenerative Medicine $5,234,731
Clinical Trial Stage Projects Prof. John A Zaia Evaluation and Characterization of SARS-CoV-2 Antibody in Convalescent Volunteer Plasma Donors for Potential Therapeutic Use $999,999
Discovery Research Projects Dr Jianhua Yu Persistent Off-the-Shelf meACE2-CAR-IL-15 NK Cells Derived from CD34(+) Cord Blood Stem Cells to Prevent and Treat COVID-19 $150,000
Alpha Stem Cell Clinics Network Expansion Dr. Leo D Wang The City of Hope Alpha Clinic: A roadmap for equitable and inclusive access to regenerative medicine therapies for all Californians $8,000,000
Conference – The 2017 Alpha Stem Cell Clinic Annual Symposium Prof. John A Zaia 2nd Annual Symposium of the CIRM Alpha Stem Cell Clinics Network “Alpha Clinics – Making the Future a Reality for Stem Cell-Based Therapies” $79,287
Conference – Manage The SPARK Annual Meeting Dr. Paul M. Salvaterra Manage the 2017 SPARK Annual Meeting $22,555
Quest – Discovery Stage Research Projects Dr Jianhua Yu Reprogramming Somatic Cells into iPSCs Engineered with an Anti-PSCA CAR to Develop Allogeneic Off-the-Shelf Cell Therapy to Treat Pancreatic Cancer $2,263,500
Quest – Discovery Stage Research Projects Professor Yanhong Shi Combating COVID-19 using human PSC-derived NK cells $249,998
Quest – Discovery Stage Research Projects Dr Saul J Priceman Chimeric Antigen Receptor-Engineered Stem/Memory T Cells for the Treatment of Recurrent Ovarian Cancer $1,351,174
Quest – Discovery Stage Research Projects Dr. Saswati Chatterjee Genome Editing of Sinusoidal Endothelial Stem Cells for Permanent Correction of Hemophilia A $2,182,193
Quest – Discovery Stage Research Projects Professor Yuan Chen A Novel Approach to Eradicate Cancer Stem Cells $1,539,935
Quest – Discovery Stage Research Projects Markus Müschen Lgr5-mediated self-renewal in B cell selection and leukemia-initiation $2,183,223
Therapeutic Translational Research Projects Dr Michael A. Caligiuri Targeting multiple myeloma with BCMA-CAR NK cells expressing a GPRC5D-NKG2D bispecific antibody $6,036,001
Therapeutic Translational Research Projects Dr Jianhua Yu Specific Targeting Hypoxia Metastatic Breast Tumor with Allogeneic Off-the-Shelf Anti-EGFR CAR NK Cells Expressing an ODD domain of HIF-1α $6,036,002
Therapeutic Translational Research Projects Prof. Karen S Aboody M.D. Neural Stem cell-mediated oncolytic immunotherapy for ovarian cancer $2,873,262
Therapeutic Translational Research Projects Dr. Yanhong Shi Ph.D. Process development for establishing an iPSC-based therapeutic candidate for Canavan disease $7,377,384
SPARK Dr. David Kong Ann Train, Educate, and Accelerate Mastery of Stem cell research (TEAMS) program $508,750
SPARK Dr. Paul M. Salvaterra SPARK Award Program in Stem Cell Biology for California High School Students $241,080
Conference II Fouad Kandeel 2016 Rachmiel Levine-Arthur Riggs Diabetes Research Symposium $10,000
Clinical Trial Stage Projects Elizabeth Budde Phase I Study of Chimeric Antigen Receptor Engineered T Cells targeting CD33 for the Treatment of Relapsed/Refractory Acute Myeloid Leukemia $11,983,547
Clinical Trial Stage Projects Dr. Angelo Manuel Almeida Cardoso Ph.D., MD Evaluation of Safety and Feasibility of Cytomegalovirus-Specific, Anti-HIV Chimeric Antigen Receptor (CMV/HIV-CAR) T Cells in People with HIV $11,299,976
Clinical Trial Stage Projects Ryotaro Nakamura Treatment of Severe Aplastic Anemia by induction of mixed chimerism using CD4+ T cell depleted haploidentical donor stem cell transplant $9,054,216
Clinical Trial Stage Projects Dr Jana Portnow A Phase I Study of Multiple doses of NSC-Based Oncolytic Virotherapy Administered Intracerebrally to Patients with Recurrent High-Grade Gliomas $11,999,984
Clinical Trial Stage Projects Dr. Leo D Wang Phase I Study of IL13Rα2-Targeting CAR T Cells After Lymphodepletion for Children with Refractory or Recurrent Malignant Brain Tumors $8,401,309
Clinical Trial Stage Projects Dr Saul J Priceman A Phase I Study of Chimeric Antigen Receptor Engineered Stem/Memory T Cells for the Treatment of HER2-Positive Brain Metastases $9,015,149
Clinical Trial Stage Projects Dr. De-Fu Zeng Treatment of sickle cell disease by induction of mixed chimerism and immune tolerance using CD4+ T-depleted haploidentical blood stem cell transplant $4,352,180
Clinical Trial Stage Projects Dr. Christine E. Brown Phase I Study of Chimeric Antigen Receptor Engineered Central Memory T cells for the Treatment of Malignant Glioma $12,753,854
Late Stage Preclinical Projects Prof. Karen S Aboody M.D. Neural stem cell delivered CRAd-S-pk7 oncolytic viro-immunotherapy for ovarian cancer $5,314,547
Late Stage Preclinical Projects Xiuli Wang CMV-specific T cells expressing anti-HIV CAR and CMV vaccine boost as immunotherapy for HIV/AIDS $3,812,797
Late Stage Preclinical Projects Dr. Angelo Manuel Almeida Cardoso Ph.D., MD Ex Vivo Gene Engineering of Blood Stem Cells for Enhanced Chemotherapy Efficacy in Glioblastoma Patients $3,684,259
Alpha Stem Cell Clinics Prof. John A Zaia The Innovation-Alpha Clinic for Cellular Therapies (I-ACT) – A Program for the Development and Delivery of Innovative Cell-based Treatments and Cures for Life-threatening Diseases. $8,416,531
Tools and Technologies III Joseph D Gold Development of a scalable, practical, and transferable GMP-compliant suspension culture-based differentiation process for cardiomyocyte production from human embryonic stem cells. $891,518
Conference Fouad Kandeel 15th Annual Rachmiel Levine Diabetes and Obesity Symposium $20,000
Conference Richard Jove Innovative Partnerships: Bringing Stem Cell Discoveries to the Clinic $14,994
Conference Richard Jove Innovation and Translational Stem Cell Therapy for Diabetes and Neurological Diseases: Paving the way for real life solutions $14,878
Conference Richard Jove New Approaches in Cell Based Therapies $20,000
Conference Fouad R Kandeel 2012 Rachmiel Levine Diabetes and Obesity Symposium: Advances in Diabetes Research $15,000
Conference Fouad R Kandeel 2011 Rachmiel Levine Diabetes and Obesity Symposium: Advances in Diabetes Research $15,000
Conference Fouad R Kandeel 2013 Rachmiel Diabetes and Obesity Levine Symposium – Advances in Diabetes Research $27,750
Conference Fouad R Kandeel 2009 Rachmiel Levine Diabetes and Obesity Symposium: Advances in Diabetes Biology, Immunology and Cell Therapy $15,000
Strategic Partnership III Track A Prof. John A Zaia A Phase I, Open-Label Study To Assess The Safety, Feasibility and Engraftment of Zinc Finger Nucleases (ZFN) CCR5 Modified Autologous CD34+ Hematopoietic Stem/Progenitor Cells (SB-728MR-HSPC) with Escalating Doses of Busulfan In HIV-1 (R5) Infected Sub… $5,583,438
Disease Team Planning Dr. Michael E. Barish Ph, D. Genetically-modified neural stem cells for treatment of high-grade glioma $55,000
Creativity Awards Dr. Paul M. Salvaterra Creativity Award Program in Stem Cell Biology for California High School Students $260,825
Basic Biology IV Dr. Yanhong Shi Ph.D. Modeling Alexander disease using patient-specific induced pluripotent stem cells $1,366,656
Early Translational III Dr. Stephen J Forman Targeting glioma cancer stem cells with receptor-engineered self-renewing memory T cells $5,215,447
Research Training II Dr. Michael E. Barish Ph, D. City of Hope Research Training Program in Stem Cell Biology $2,197,782
Basic Biology III Dr. Jiing-Kuan Yee Ph.D. Use of human iPS cells to study spinal muscular atrophy $1,268,868
Early Translational II Dr. Yanhong Shi Ph.D. Developing a therapeutic candidate for Canavan disease using induced pluripotent stem cell $1,835,983
Early Translational II Dr. David Louis DiGiusto Development of RNA-based approaches to stem cell gene therapy for HIV $3,097,160
New Faculty I Dr. Tiziano Barberi Skeletal muscle development from hESC and its in vivo applications in animal models of muscular dystrophy $131,840
Tools and Technologies I Joseph Shi Gold Development of Suspension Adaptation, Scale-up cGMP Banking and Cell Characterization Technologies for hESC Lines $882,929
SEED Grant Dr. Timothy R. O’Connor Sources of Genetic Instability in Human Embryonic Stem Cells. $327,311
Disease Team Research I Prof. Karen S Aboody M.D. Stem Cell-mediated Therapy for High-grade Glioma: Toward Phase I-II Clinical Trials $17,890,623
Disease Team Research I Prof. John A Zaia ZINC FINGER NUCLEASE-BASED STEM CELL THERAPY FOR AIDS $14,536,969
Total:
$205,110,567.94