University of California, Irvine

Return to Grants

Total Awards:
72
Award Value:
$164,939,918
Institution type:
Not for profit
Short Name:
UC Irvine

Awards to the Institution

Program Type Investigator Grant Title Award Value
Shared Labs Grant – Enhancing/Expanding SRLs Craig M. Walsh Shared Resources Laboratories to Enhance In Vitro Stem Cell Modeling and Training $3,641,396
Manufacturing Network Grant Dr. Aileen J Anderson The UCI GMP Cell and Gene Therapy Manufacturing Facility $2,000,000
Foundation – Discovery Stage Research Projects Albert La Spada Ph.D. Role of ataxin-3 polyadenylation site selection in ALS neuron toxicity and disease pathogenesis $1,514,416
Foundation – Discovery Stage Research Projects Dr. Brian J. Cummings Mapping the spatial and temporal responses of hESC-derived microglia to repeat mild closed head injury to identify therapeutic targets and mechanisms $1,339,685
Foundation – Discovery Stage Research Projects Momoko Watanabe Generation of cortical organoids with tunable areal identities by spatial engineering of morphogens $0
COMPASS Training Grant Dr. Brian J. Cummings Research Mentorship Program in Regenerative Medicine Careers for a Diverse Undergraduate Student Body $2,729,900
Research Training Grant Dr. Peter J Donovan CIRM Scholars Comprehensive Research Training Program $5,373,742
Conference – The 2020 Grantee Meeting Daniela A. Bota 2020 CIRM Grantee Meeting $176,762
Conference – The Alpha Stem Cell Clinic Annual Symposium Daniela A. Bota 2023 Alpha Stem Cell Clinic Annual Symposium $49,512
Progression Award – Discovery Stage Research Projects Dr. Brian J. Cummings Human neural stem cell (hNSC) derived exosomes vs CSC14 hNSCs for the treatment of traumatic brain injury (TBI) $202,667
Alpha Stem Cell Clinics Network Expansion Daniela A. Bota A hub and spoke community model to equitably deliver regenerative medicine therapies to diverse populations across four California counties $8,000,000
Quest – Discovery Stage Research Projects Dr. Michael Demetriou CAR T cells targeting abnormal N-glycans for the treatment of refractory/metastatic solid cancers $1,414,800
Quest – Discovery Stage Research Projects Dr. Mathew Mark Blurton-Jones Transplantation of genetically corrected iPSC-microglia for the treatment of Sanfilippo Syndrome (MPSIIIA) $1,083,379
Quest – Discovery Stage Research Projects Munjal M Acharya Stem cell-derived extracellular vesicles to reverse radiation-induced brain injury $1,064,724
Quest – Discovery Stage Research Projects Robert F. Hunt Optimization of a human interneuron cell therapy for traumatic brain injury $240,000
Quest – Discovery Stage Research Projects Dr. Mathew Mark Blurton-Jones Transplantation of Pluripotent Stem Cell Derived Microglia for the Treatment of Adult-onset Leukoencephalopathy (HDLS/ALSP) $214,668
Quest – Discovery Stage Research Projects Dr. Aileen J Anderson Generation and in vitro profiling of neural stem cell lines to predict in vivo efficacy for chronic cervical spinal cord injury. $1,575,613
Quest – Discovery Stage Research Projects Dr. Brian J. Cummings Identification and characterization of the optimal human neural stem cell line (hNSC) for the treatment of traumatic brain injury (TBI) 2.0. $1,671,213
Quest – Discovery Stage Research Projects Leslie M Thompson hNSC-mediated delivery of ApiCCT1 as a candidate therapeutic for Huntington’s disease $1,650,263
Inception – Discovery Stage Research Projects Janet E Baulch An exosome-based translational strategy to mitigate Alzheimer’s disease neuropathology $157,650
Therapeutic Translational Research Projects Dr. Aileen J Anderson A human neural stem cell therapeutic candidate for the treatment of chronic cervical spinal cord injury $4,950,024
Therapeutic Translational Research Projects Dr. Brian J. Cummings An optimized human neural stem cell line (hNSC) for the treatment of traumatic brain injury (TBI) $4,804,737
Therapeutic Translational Research Projects Dr. Magdalene J Seiler Morphological and functional integration of stem cell derived retina organoid sheets into degenerating retina models $4,769,039
Conference II Dr. Brian J. Cummings University of California, Irvine Conference on Concussion, TBI, and CTE in Athletes and Veterans $38,070
Conference II Leslie M Thompson Advanced Therapies and Stem Cells for Huntington’s disease $27,388
Conference II Dr. Mathew Mark Blurton-Jones ALSP Community Conference: Insights and Potential of Cell-Based Therapies for the Treatment of Leukodystrophies $40,499
Conference II Olga V Razorenova UCI Stem Cell Research Center 9th Annual Stem Cell Science Symposium $8,366
Conference II Dr. Leslie M Thompson Stem Cells for Huntington’s Disease (HD) International (SC4HDI) Conference $31,727
Conference II Dr. LESLIE M Thompson HD-CARE INAUGURAL SYMPOSIUM $1,500
Conference II Dr. Sidney Golub Human Research In Times of Controversy: From Stem Cells To Fetal Tissue $13,562
Late Stage Preclinical Projects Kyriacos A Athanasiou Treatment of the TMJ disc complex $6,000,000
Late Stage Preclinical Projects Dr. Leslie M Thompson An hESC-derived hNSC Therapeutic for Huntington’s Disease $5,635,393
Preclinical Development Awards Dr. Leslie M Thompson A hNSC Development Candidate for Huntington’s Disease $4,951,623
Tools and Technologies III Dr. Mathew Mark Blurton-Jones Optimizing the differentiation and expansion of microglial progenitors from human pluripotent stem cells for the study and treatment of neurological disease. $1,147,596
Conference Dr. Peter J Donovan Systems Biology of Stem Cells $25,000
Conference Dr. Michelle Khine UC Systemwide Bioengineering Symposium $7,525
Disease Team Planning Dr. Leslie M Thompson Huntington’s Disease Team $41,953
Disease Team Planning Dr. Henry John Klassen Stem cells for neuroprotection of photoreceptors in retinitis pigmentosa $23,537
Major Facilities Dr. Michael V Drake UC Irvine CIRM Institute $27,156,000
Basic Biology V Dr. Peter J Donovan Non-invasive live imaging of stem cell signature metabolic states $516,366
Basic Biology V Dr. Lisa A Flanagan Molecular basis of plasma membrane characteristics reflecting stem cell fate potential $994,108
Patent Assistance Fund Awards Ronnie Hanecak CIRM Patent Assistance Fund Application – UCI $46,155
Early Translational IV Dr. Magdalene J Seiler Restoring vision by sheet transplants of retinal progenitors and retinal pigment epithelium (RPE) derived from human embryonic stem cells (hESCs) $3,998,948
Disease Team Therapy Development – Research Dr. Henry John Klassen Retinal progenitor cells for treatment of retinitis pigmentosa $17,144,825
Early Translational III Craig M. Walsh Multiple Sclerosis therapy: Human Pluripotent Stem Cell-Derived Neural Progenitor Cells $4,535,005
Training Grant I-1 Dr. Peter Bryant Stem Cell Research Training Grant $1,935,487
Research Training II Dr. Peter John Donovan Dr. UCI-CIRM Research Training Program II $6,067,550
Early Translational II Dr. Brian J. Cummings Neural restricted, FAC-sorted, human neural stem cells to treat traumatic brain injury $1,517,767
Early Translational II Leif A Havton Repair of Conus Medullaris/Cauda Equina Injury using Human ES Cell-Derived Motor Neurons $1,527,011
Early Translational II Dr. Henry John Klassen Human retinal progenitor cells as candidate therapy for retinitis pigmentosa $1,803,768
Early Translational II Dr. Leslie M Thompson A hESc-based Development Candidate for Huntington’s Disease $3,955,038
New Faculty I Dr. Andrew Putnam A Novel Engineered Niche to Explore the Vasculogenic Potential of Embryonic Stem Cells $395,764
Early Translational I Dr. Frank LaFerla Neural Stem Cells as a Developmental Candidate to Treat Alzheimer Disease $3,599,997
Tools and Technologies I Dr. Lisa A Flanagan Novel Separation of Stem Cell Subpopulations $861,122
Tools and Technologies I Dr. Orhan NALCIOGLU A MULTI-MODALITY MOLECULAR IMAGING SYSTEM (MRSPECT) FOR IN VIVO STEM CELL TRACKING $719,798
Shared Labs Dr. Peter J Donovan The University of California: Irvine Regional Human Embryonic Stem Cell Shared Research Laboratory and Stem Cell Techniques Course $2,107,376
Shared Labs Dr. Peter John Donovan Dr. The University of California: Irvine Regional Human Embryonic Stem Cell Shared Research Laboratory and Stem Cell Techniques Course $3,072,500
New Faculty II Dr Edwin S Monuki Mechanisms in Choroid Plexus Epithelial Development $2,793,395
New Cell Lines Dr. Leslie M Thompson New Cell Lines for Huntington’s Disease $1,302,526
Comprehensive Grant Dr Hans S Keirstead hESC-Derived Motor Neurons For the Treatment of Cervical Spinal Cord Injury $2,158,445
Comprehensive Grant Dr. Peter John Donovan Improved hES Cell Growth and Differentiation $2,381,713
Comprehensive Grant Dr. Douglas C. Wallace The Dangers of Mitochondrial DNA Heteroplasmy in Stem Cells Created by Therapeutic Cloning $1,790,133
SEED Grant Dr. Kyoko Yokomori Derivation and characterization of human ES cells from FSHD embryos $607,200
SEED Grant Dr. Vincent Procaccio Mitochondrial Dysfunction in Embryonic Stem Cells $245,397
SEED Grant Dr. Grant R MacGregor Production of Oocytes from Human ES Cells $385,466
SEED Grant Thomas Edward Lane Human Embryonic Stem Cells and Remyelination in a Viral Model of Demyelination $368,081
SEED Grant Dr. Frank LaFerla Development of human ES cell lines as a model system for Alzheimer disease drug discovery $473,963
SEED Grant Professor Charles L Limoli Using human embryonic stem cells to treat radiation-induced stem cell loss: Benefits vs cancer risk $593,242
SEED Grant Dr. Brian J. Cummings The Immunological Niche: Effect of immunosuppressant drugs on stem cell proliferation, gene expression, and differentiation in a model of spinal cord injury. $595,345
SEED Grant Dr. Michelle Khine Micro Platform for Controlled Cardiac Myocyte Differentiation $156,426
Basic Biology II Professor Marian L Waterman TCF-3: A Wnt Pathway Effector and Nanog Regulator in Pluripotent Stem Cell Self-Renewal $1,259,879
Basic Biology II Dr. Aileen J Anderson Role of the microenvironment in human iPS and NSC fate and tumorigenesis $1,256,194
Total:
$164,939,918.43