CIRM Funded Clinical Trials

MSC engineered to produce BDNF for the treatment of Huntington’s disease

Disease Area:
CIRM Grant:
DR2A-05415 (Closed)
Award Value:
Trial Sponsor:
The Regents of the University of California, on behalf of its Davis campus
Trial Stage:
Phase 1/2
Trial Status:
Targeted Enrollment:
29 ID:


A team at UC Davis plans to use bone marrow derived mesenchymal stem cells to deliver a growth factor, called BDNF, to patients’ brains in order to reduce the death of nerve cells that occurs in Huntington’s Disease (HD). In preparation for such a clinical trial study, the team completed a CIRM-funded observational trial in a group of HD patients to study the progression of disease.


This trial is completed.

CIRM Clinical Trial Resources

Patient Stories of Hope

CIRM Alpha Stem Cell Clinics

Patient Toolbox

Video on Stem Cell Trials

Other Resources

ISSCR Patient Website