About Alpha Clinics

The CIRM-funded Alpha Stem Cell Clinics are a network of top California medical centers. The Network specializes in delivering stem cell clinical trials to patients. The key to the Network’s success is the ability to accelerate the delivery of treatments to patients through partnerships with patients, medical providers and clinical trial sponsors. These partnerships enable:

  • Patient-centered clinical trials with the highest standards of care and research
  • Strategic collaboration with academic and industry teams developing innovative stem cell therapies
  • Leveraging of resources to promote efficiency, acceleration and increased chances of success

The Network supports both CIRM-funded and non CIRM-funded clinical trials by academic and industry sponsors. 










If you are a patient or a trial sponsor interested in learning more about the services offered through our Alpha Clinics Network contact us at alphaclinics@cirm.ca.gov.

Our Alpha Clinics

The CIRM Alpha Stem Cell Clinic Network consists of five leading medical centers throughout California. In 2015, the Network was launched in southern California at the City of Hope, UC Irvine/UC Los Angeles, and UC San Diego. In September 2017, CIRM awarded funding to UC Davis and UC San Francisco to enable the Network to better serve patients throughout the state.

To learn more about participating Alpha Clinics—including information on enrolling in current and future clinical trials—please visit each clinic's dedicated webpage*. 



COVID-19 Clinical Programs & Trials

As a response to the novel coronavirus pandemic, CIRM has allocated $5 million in emergency funding for COVID-19 related projects. CIRM has supported three clinical programs that place an emphasis on treating underserved communities as well as incorporating the Alpha Clinics Network into their trial sites. These three programs include the following: a convalescent plasma study conducted by Dr. John Zaia at City of Hope, a treatment for acute respiratory distress syndrome (a serious and lethal consequence of COVID-19) conducted by Dr. Michael Matthay at UCSF, and a study using natural killer cells to treat COVID-19 patients conducted by Dr. Xiaokui Zhang at Celularity Inc. Click on the links below to learn more.

COVID-19 Plasma Study

Virtual ASCC Network Symposium

Every year, CIRM sponsors a public conference to educate, explore key issues in this developing field, and highlight results in the pursuit of stem cell and gene therapies becoming standard of care. This year on Thursday October 8, 2020, Sacramento’s UC Davis Health will host CIRM’s 5th annual Alpha Stem Cell Clinic Network Symposium as an on-line virtual meeting. Registrants will be sent a Zoom link about one week prior to the event. (Test your Zoom connection here.)

Register for the event by clicking on the link here

CIRM Alpha Clinic Videos

The 2nd Annual CIRM Alpha Stem Cell Clinic Symposium was held in March, 2017 at the City of Hope. You can watch videos of all the speakers on the City of Hope YouTube channel.

A clinical trial at the City of Hope Alpha Stem Cell Clinic brings hope for patients with glioblastoma, an aggressive form of brain cancer. A patient with late stage glioblastoma was treated with a cell-based immunotherapy called CAR T-cells. After ten treatments, the patient's tumors disappeared and didn't return for seven months.

In May 2015, the three Network programs from UCSD, City of Hope, and the UCLA/UCI consortium joined CIRM at the City of Hope campus for a kickoff workshop to mark the beginning of the endeavor. This short video is based on that workshop and features interviews with each trial center’s program director.​

For more Alpha Clinic videos, visit our CIRM Alpha Stem Cell Clinics channel on YouTube and our CIRM channel on The Science Network.

Find Out More:

Alpha Clinics in the News
Alpha Clinics Trials