University of California, San Diego

Return to Grants

Total Awards:
137
Award Value:
$286,590,070
Institution type:
Not for profit
Short Name:
UCSD

Awards to the Institution

Program Type Investigator Grant Title Award Value
Manufacturing Network Grant Dan S Kaufman UCSD Advanced Cell Therapy Laboratory $2,000,000
Foundation – Discovery Stage Research Projects Dr Marianna Alperin Harnessing the rejuvenating capacity of pregnancy-associated factors to restore aged stem cell function $1,539,520
Foundation – Discovery Stage Research Projects Dr. Alon Goren Establishment of a novel approach to systematically study the dynamic organization of protein complexes in stem cells $1,515,601
Foundation – Discovery Stage Research Projects Heidi Cook-Andersen Towards a trophectoderm stem-cell model representing human blastocysts of the highest implantation potential $1,584,000
Foundation – Discovery Stage Research Projects Dr. Alexis Komor Development of a stem-cell based approach to interpret global effects of genetic variants contributing to neurodevelopmental disease risk $1,518,982
Foundation – Discovery Stage Research Projects Francesca Soncin Drivers of trophoblast stem/progenitor cell identity in human placenta $993,881
Research Training Grant Professor Alysson R Muotri Interdisciplinary Stem Cell Training Grant at UCSD III $5,366,188
Discovery Research Projects Dr. Steven F Dowdy Development of Anti-COVID RNAi Therapeutics Using Human iPSC-Derived Alveolar Epithelial Cells $150,000
Discovery Research Projects Dr Karen Christman Pro-healing biomaterial for treating lung inflammation associated with COVID-19 $221,758
Progression Award – Discovery Stage Research Projects Armin Blesch Simplification of Excipient Solution for Implanting Candidate Human H9-scNSC Cell Line for Spinal Cord Injury $180,000
Alpha Stem Cell Clinics Network Expansion Catriona Jamieson UC San Diego Health CIRM Alpha Stem Cell Clinic $8,000,000
Conference – The 2016 Alpha Stem Cell Clinic Annual Symposium Catriona Jamieson UCSD Division of Regenerative Medicine and CIRM Alpha Clinics Network Symposium $37,778
Quest – Discovery Stage Research Projects Professor Alysson R Muotri A treatment for Rett syndrome using glial-restricted neural progenitor cells $1,402,240
Quest – Discovery Stage Research Projects Dr. Joseph G. Gleeson Novel antisense therapy to treat genetic forms of neurodevelopmental disease. $1,180,654
Quest – Discovery Stage Research Projects Dr. Michael Karin Targeting pancreatic cancer stem cells with DDR1 antibodies. $1,425,600
Quest – Discovery Stage Research Projects Gene Wei-Ming Yeo RNA-directed therapy for Huntington’s disease $1,253,110
Quest – Discovery Stage Research Projects Ziwei Huang Development of a new therapeutic for directing target specific stem cell migration and treatment $1,129,512
Quest – Discovery Stage Research Projects Dan S Kaufman Human iPSC-derived chimeric antigen receptor expressing macrophages for improved cancer treatment. $1,256,332
Quest – Discovery Stage Research Projects Dr. Tannishtha Reya Targeting Critical Regulators of Cancer Stem Cells $1,148,264
Quest – Discovery Stage Research Projects Tariq M Rana Development of COVID-19 Antiviral Therapy Using Human iPSC-Derived Lung Organoids $250,000
Quest – Discovery Stage Research Projects Dan S Kaufman Human iPSC-derived chimeric antigen receptor-expressing macrophages for cancer treatment $222,200
Quest – Discovery Stage Research Projects Prof James S Hagood Mesenchymal stem cell extracellular vesicles as therapy for pulmonary fibrosis $0
Quest – Discovery Stage Research Projects Dr. Eric D. Adler MD Genetically Modified Hematopoietic Stem Cells for the Treatment of Danon Disease $1,393,200
Quest – Discovery Stage Research Projects Dr. Jonathan H Lin Small Molecule Proteostasis Regulators to Treat Photoreceptor Diseases $1,153,937
Quest – Discovery Stage Research Projects Dr. Tannishtha Reya Targeting Cancer Stem Cells in Hematologic Malignancies $1,960,560
Quest – Discovery Stage Research Projects Mark H Tuszynski Neural Stem Cell Relays for Severe Spinal Cord Injury $1,638,900
Quest – Discovery Stage Research Projects Dr Yang Xu Development of immune invisible beta cells as a cell therapy for type 1 diabetes through genetic modification of hESCs $1,924,791
Quest – Discovery Stage Research Projects Professor Yuan Chen A Novel Approach to Eradicate Cancer Stem Cells $279,977
Quest – Discovery Stage Research Projects Professor Alysson R Muotri A treatment for Zika virus infection and neuroprotection efficacy $1,924,524
Quest – Discovery Stage Research Projects Dan S Kaufman Targeted off-the-shelf immunotherapy to treat refractory cancers $1,936,936
Inception – Discovery Stage Research Projects Karl Karl J. Wahlin An IPSC cell based model of macular degeneration for drug discovery. $232,200
Inception – Discovery Stage Research Projects Gerald P Morris Identification of antigenic neo-epitopes from in vitro reprogrammed human tissue precursors for regenerative therapy $193,500
Inception – Discovery Stage Research Projects Dr. Tannishtha Reya Reprogramming human stem cells for blood cell generation $210,060
Inception – Discovery Stage Research Projects Professor Alysson R Muotri Reverse transcriptase inhibitors as a novel therapeutic approach for neurological autoimmune disorders $210,060
Inception – Discovery Stage Research Projects Dionicio Siegel New Methods for the Chemical Expansion of Hematopoietic Stem and Progenitor Cells $232,200
Inception – Discovery Stage Research Projects Karl Karl J. Wahlin Microenvironment based optimization of retinal induction using CRISPR-CAS9 reporter pluripotent stem cells as an expandable source of retinal progenitors and photoreceptors. $232,200
Therapeutic Translational Research Projects Dr Karen Christman Pro-regenerative infusible ECM biomaterial for treating acute myocardial infarction $4,353,438
Therapeutic Translational Research Projects Dr. Eric D. Adler MD Ex Vivo Modified Hematopoietic Stem Cells to Treat Danon Disease $5,180,389
Therapeutic Translational Research Projects Stephanie Cherqui CRISPR/Cas9-mediated gene editing of Hematopoietic stem and progenitor cells for Friedreich’s ataxia $4,846,579
Therapeutic Translational Research Projects Mark H Tuszynski Human Embryonic Stem Cell-Derived Neural Stem Cells for Severe Spinal Cord Injury (SCI) $6,235,897
Therapeutic Translational Research Projects Dan S Kaufman Human Embryonic Stem Cell-Derived Natural Killer Cells for Cancer Treatment $3,260,000
Therapeutic Translational Research Projects Catriona Jamieson A Splicing Modulator Targeting Cancer Stem Cells in Acute Myeloid Leukemia $2,511,767
Therapeutic Translational Research Projects Ezra Cohen Development of ROR1 CAR-T cells to target cancer stem cells in advanced malignancies $5,795,584
Therapeutic Translational Research Projects Dr Karen Christman Injectable pro-regenerative scaffold for treating symptomatic peripheral artery disease $2,839,317
Therapeutic Translational Research Projects Dr. Lawrence S. B. Goldstein Human Embryonic Stem Cell-Derived Neural Stem Cell Transplants in Amyotrophic Lateral Sclerosis $1,790,000
SPARK James Murphy Summer Program To Accelerate Regenerative Medicine Knowledge (SPARK) $503,846
Conference II Dr. Adam Engler BIC 2024 – 24th Annual UC Systemwide Symposium on Bioengineering at UC San Diego $50,000
Conference II Dr. Robert Lie-Yuan Sah 2016 Tissue Engineering and Regenerative Medicine International Society – Americas (TERMIS-AM) Conference in San Diego, CA on December 11-14, 2016 $40,000
Conference II Prof. John M. Ravits California ALS Research Summit 2016 $11,400
Clinical Trial Stage Projects Prof. Olivia Kim-McManus Personalized antisense oligonucleotide therapy for rare pediatric genetic disease: SCN2A $960,713
Clinical Trial Stage Projects Dr. Stephanie Cherqui Phase 1/2 study for autologous human CD34+ hematopoietic stem cells ex vivo transduced with pCCL-CTNS lentiviral vector for treatment of Cystinosis. $11,999,944
Clinical Trial Stage Projects Thomas J Kipps A Phase 1b/2a Study of the ROR1-Targeting Monoclonal Antibody, Cirmtuzumab, and the Bruton Tyrosine Kinase Inhibitor, Ibrutinib, in B-Cell Cancers $18,292,674
Late Stage Preclinical Projects Mark H Tuszynski Human Embryonic Stem Cell-Derived Neural Stem Cells for Severe Spinal Cord Injury (SCI) $6,000,000
Late Stage Preclinical Projects Thomas J Kipps Late Stage Pre-Clinical Development of a Cirmtuzumab Based CAR T-cell for the Treatment of ROR1+ Hematological Malignancies $2,160,000
Late Stage Preclinical Projects Dr. Stephanie Cherqui Ex vivo transduced autologous human CD34+ hematopoietic stem cells for treatment of cystinosis $5,273,189
Alpha Stem Cell Clinics Catriona Jamieson Alpha Stem Cell Clinic for the Development of Regenerative Therapies $8,679,137
Tools and Technologies III Dr. Shyni Varghese Technologies to improve in vivo function of transplanted stem cells $1,373,683
Tools and Technologies III Shaochen Chen Development of 3D Bioprinting Techniques using Human Embryonic Stem Cells Derived Cardiomyocytes for Cardiac Tissue Engineering $1,368,264
Conference Shu Chien 10th Annual UC Systemwide Bioengineering Symposium $8,000
Conference Shu Chien The 14th UC Systemwide Bioengineering Symposium $5,000
Conference Prof. John M. Ravits Cell Therapy for amyotrophic Lateral Sclerosis (ALS) -Testing the Limits: What should we use as preclinical standards of clinical trials? $7,193
Conference Dong-Er Zhang International RUNX Workshop $24,000
Conference Dr. Lawrence S. B. Goldstein San Diego Stem Cell Science Education Symposium at UCSD $6,237
Conference Dr. Joan Heller Brown International Society for Heart Research (ISHR) XX1 World Congress $10,000
Disease Team Planning Dr. Dennis Carson CIRM Planning Grant in Leukemia $52,174
Disease Team Planning Lawrence Goldstein Human Stem Cell Approaches to Alzheimers Disease Therapies $55,000
Basic Biology V Dr. Dianne McKay Role of intracytoplasmic pattern recognition receptors in HSC engraftment $615,639
Basic Biology V Christian Metallo Metabolic regulation of cardiac differentiation and maturation $1,124,834
Basic Biology V Maike Sander Defining links between chromatin state and developmental competence $1,050,300
Basic Biology V Miles F Wilkinson New Regulators of Spermatogonial Stem Cells: RHOX Homeobox Transcription Factors $552,811
Basic Biology V Dr. Cornelis Murre Epigenetic mechanisms that enforce pluripotency in embryonic stem cells $1,160,997
Basic Biology V Dr. Wei Wang Systems-level discovery of the regulatory mechanisms directing differentiation of hESC $1,161,000
Basic Biology V Dr. Lawrence S. B. Goldstein Elucidating pathways from hereditary Alzheimer mutations to pathological tau phenotypes $1,050,300
Basic Biology V Dr. David A. Cheresh CD61-driven stemness program in epithelial cancer $1,161,000
Disease Team Therapy Development III Thomas J Kipps Therapeutic Eradication of Cancer Stem Cells with UC-961 (Cirmtuzumab) $4,179,598
Patent Assistance Fund Awards Dr. Rubén D. Flores Patent Assistance Fund Application – UCSD $38,162
Early Translational from Disease Team Conversion Dr. Lawrence S. B. Goldstein Stem Cell-Derived Astrocyte Precursor Transplants in Amyotrophic Lateral Sclerosis $4,139,754
Early Translational IV Professor Alysson R Muotri A drug-screening platform for autism spectrum disorders using human astrocytes $1,656,456
Tissue Collection for Disease Modeling Dr. Joseph G. Gleeson CIRM Tissue Collection for Neurodevelopmental Disabilities $830,426
Tissue Collection for Disease Modeling Dr. Kang Zhang M.D. Generation of fibroblast cell lines in patients with common blinding eye diseases $1,034,425
Tissue Collection for Disease Modeling Dr. James Brewer Collection of skin biopsies to prepare fibroblasts from patients with Alzheimer’s disease and cognitively healthy elderly controls $643,693
New Faculty Physician Scientist Dr. Mana M Parast Human pluripotent stem cell-based therapeutics for preeclampsia $2,974,750
Basic Biology IV George Sen Regulation of Epidermal Self-Renewal and Differentiation by Histone and DNA Demethylases. $1,080,000
Basic Biology IV Miles F Wilkinson Role of the NMD RNA Decay Pathway in Maintaining the Stem-Like State $1,360,450
Basic Biology IV Ananda Goldrath Mechanisms to protect hESC-derived cells from allogenic immune rejection $1,160,997
Basic Biology IV Maike Sander Deciphering transcriptional control of pancreatic beta-cell maturation in vitro $1,258,560
Basic Biology IV Dr. David Traver DECIPHERING THE INSTRUCTIONS FOR VERTEBRATE HSC SPECIFICATION AND AMPLIFICATION. $1,363,698
Basic Biology IV Gene Wei-Ming Yeo Stem cell models to analyze the role of mutated C9ORF72 in neurodegeneration $1,260,360
Early Translational III Dr. Lawrence S. B. Goldstein Identifying Drugs for Alzheimer’s Disease with Human Neurons Made From Human IPS cells $1,774,420
Early Translational III Dr. Yang Xu Human ES cell based therapy of heart failure without allogenic immune rejection $1,857,600
Early Translational III Dr. Eric D. Adler MD Identification of Novel Therapeutics for Danon Disease Using an iPS Model of the Disease $1,701,575
Early Translational III Mark H Tuszynski Functional Neural Relay Formation by Human Neural Stem Cell Grafting in Spinal Cord Injury $4,600,447
Early Translational III Gene Wei-Ming Yeo Molecules to Correct Aberrant RNA Signature in Human Diseased Neurons $1,532,323
Training Grant I-1 Dr. Lawrence S. B. Goldstein Interdisciplinary Stem Cell Training Program at UCSD $3,459,396
Research Training II Dr Sylvia Evans Interdisciplinary Stem Cell Training Program at UCSD II $7,432,600
Basic Biology III Dr. Deborah H Spector Dr. Viral-host interactions affecting neural differentiation of human progenitors $1,372,660
Basic Biology III Dr. David A. Cheresh Molecular basis of human ES cell neurovascular differentiation and co-patterning $1,359,996
Basic Biology III Dr. Anirvan Ghosh Dr. Investigation of synaptic defects in autism using patient-derived induced pluripotent stem cells $843,597
Basic Biology III Dr. Kun Zhang Functional characterization of mutational load in nuclear reprogramming and differentiation $1,295,318
Basic Biology III Gene Wei-Ming Yeo Neural and general splicing factors control self-renewal, neural survival and differentiation $1,287,619
Basic Biology III Dr. Benhai Zheng Dr. Generation and characterization of corticospinal neurons from human embryonic stem cells $1,355,063
Basic Biology III Dr. Farah Sheikh Dr. Molecular Mechanisms Underlying Human Cardiac Cell Junction Maturation and Disease Using Human iPSC $1,341,955
Basic Biology III Dr. Charles C. King Dr. Biological relevance of microRNAs in hESC differentiation to endocrine pancreas $1,313,649
Tools and Technologies II Karl H. Willert Homologous recombination in human pluripotent stem cells using adeno-associated virus. $1,659,043
Tools and Technologies II Dr. Lawrence S. B. Goldstein Developing a method for rapid identification of high-quality disease specific hIPSC lines $1,686,069
Tools and Technologies II Shu Chien Development of Synthetic Microenvironments for Stem Cell Growth and Differentiation $1,706,628
Early Translational II Professor Alysson R Muotri Developing a drug-screening system for Autism Spectrum Disorders using human neurons $1,376,198
Early Translational II Catriona Jamieson Preclinical development of a pan Bcl2 inhibitor for cancer stem cell directed therapy $3,103,041
Research Leadership Dr. Eric T. Ahrens Molecular Imaging for Stem Cell Science and Clinical Application $5,680,474
New Faculty I Dr. David Traver Genetic dissection of mesodermal commitment to the hematopoietic fates. $2,150,620
Early Translational I Dr. Yang Xu Developing induced pluripotent stem cells into human therapeutics and disease models $5,165,028
Transplantation Immunology Prof. Martin Marsala Induction of immune tolerance after spinal grafting of human ES-derived neural precursors $1,387,800
Transplantation Immunology Dr. Yang Xu Induction of immune tolerance to human embryonic stem cell-derived allografts $1,192,680
Tools and Technologies I Dr. Ying Liu Generation of disease models for neurodegenerative disorders in hESCs by gene targeting $709,829
Tools and Technologies I Dr. Steven F Dowdy TAT Cell-Permeable Protein Delivery of siRNAs for Epigenetic Programming of Human Pluripotent and Adult Stem Cells $720,000
Shared Labs Karl H. Willert Enhancing Facilities for Genetic Manipulation and Engineering of Human Embryonic Stem Cells at UCSD $1,728,080
Shared Labs Karl H. Willert Enhancing Facilities for Genetic Manipulation and Engineering of Human Embryonic Stem Cells at UCSD $1,737,133
New Faculty II Dr. Benjamin D. Yu Regulation of Adult Stem Cell Proliferation by RAS and Cell-Permeable Proteins $3,017,978
New Faculty II Dr. Shyni Varghese A Novel Microenvironment-Mediated Functional Skeletal Muscle from Human Embryonic Stem Cells and their In Vivo Engraftment $2,300,569
New Faculty II Dr. Mana M Parast Molecular Mechanisms of Trophoblast Stem Cell Specification and Self-Renewal $3,077,918
New Faculty II Catriona Jamieson Derivation and Characterization of Myeloproliferative Disorder Stem Cells from Human ES Cells $3,065,572
New Cell Lines Dr. Steven F Dowdy Protein transduction of transcription factors: a non-genetic approach to generate new pluripotent cell lines from human skin. $1,073,585
Comprehensive Grant Dr. Yang Xu Mechanisms to maintain the self-renewal and genetic stability of human embryonic stem cells $2,467,200
Comprehensive Grant Prof. Martin Marsala Spinal ischemic paraplegia: modulation by human embryonic stem cell implant. $2,356,090
Comprehensive Grant Dr. Lawrence S. B. Goldstein Using Human Embryonic Stem Cells to Understand and to Develop New Therapies for Alzheimer’s Disease $1,859,414
SEED Grant Dr. Benhai Zheng Dr. Genetic manipulation of human embryonic stem cells and its application in studying CNS development and repair $600,441
SEED Grant Dr. Anirvan Ghosh Dr. Generation of forebrain neurons from human embryonic stem cells $587,591
SEED Grant Shu Chien Combinatorial Platform for Optimizing Microenvironments to Control hESC Fate $577,148
SEED Grant Dr. Cornelis Murre Generation of long-term cultures of human hematopoietic multipotent progenitors from embryonic stem cells $473,952
SEED Grant Catriona Jamieson Derivation and Characterization of Cancer Stem Cells from Human ES Cells $616,305
SEED Grant Dr Sylvia Evans Specification of Ventricular Myocyte and Pacemaker Lineages Utilizing Human Embryonic Stem Cells $585,600
Basic Biology II Dong-Er Zhang RUNX1 in maintenance, expansion, and differentiation of therapeutic pluripotent stem cells $1,371,540
Basic Biology II Dr. Kun-Liang Guan The function of YAP in human embryonic stem cells $1,245,693
Disease Team Research I Dr. Lawrence S. B. Goldstein Stem Cell-Derived Astrocyte Precursor Transplants in Amyotrophic Lateral Sclerosis $5,694,308
Disease Team Research I Dr. Dennis A Carson Development of Highly Active Anti-Leukemia Stem Cell Therapy (HALT) $19,999,826
Basic Biology I Gene Wei-Ming Yeo RNA Binding Protein-mediated Post-transcriptional Networks Regulating HPSC Pluripotency $1,308,901
Basic Biology I Karl H. Willert WNT signaling and the control of cell fate decisions in human pluripotent stem cells. $1,329,298
Total:
$286,590,069.83