| University of California, San Francisco | Dr. Julie B Sneddon | Decoding Human Pancreatic Progenitor Biology to Enable Next-Generation Stem Cell-based Therapies for Type 1 Diabetes |
$2,499,875 |
| University of California, San Diego | Shiri Gur-Cohen | Phoenix WNTears: A Platform for Selectivity Expanding Adult Stem Cell Potency and Plasticity |
$2,500,000 |
| University of Southern California | Leonardo Morsut | Engineering Nephron Connectivity in Human Kidney Tissue Using Synthetic Signaling Centers |
$2,500,000 |
| University of California, San Diego | Sven Heinz | Decoding regulatory sequence function during human brain organoid development |
$2,500,000 |
| Salk Institute for Biological Studies | Dr. Samuel L Pfaff | Characterizing how neurons from human stem cell transplants integrate into spinal neural circuits following injury |
$2,499,999 |
| University of Southern California | Dr. Justin K Ichida | Leveraging iPSCs and a deep learning-based virtual cell model to identify therapeutic targets for ALS |
$2,500,000 |
| University of California, San Francisco | Audrey Parent | Advancing next-generation models for the development of thymoregenerative medicines |
$2,500,000 |
| California Institute of Technology | Magdalena Zernicka-Goetz | Spatiotemporal Control of Human Primordial Germ Cell Fate by the Embryonic Niche |
$2,425,796 |
| Gladstone Institutes, J. David | Christina Theodoris | Temporal AI models for programming therapeutic cell state transitions |
$2,499,998 |
| University of California, San Francisco | Dr Diana Jean Laird | Neurovascular control of follicle growth using stem-cell derived ovary assembloids |
$2,499,997 |
| University of California, Berkeley | Dr. Andreas Stahl | Generating biological age in a stem cell-based complex disease model of osteoarthritis |
$2,499,999 |
| The Regents of the University of California on behalf of its Riverside Campus | Joshua Morgan | Validating Safety and Efficacy of Extremeophile Stress Tolerance Transgenes in Stem Cells |
$2,499,999 |
| University of Southern California | Mohamed Abou-el-Enein | Revealing the Mechanistic Architecture Governing CAR-T Cell Potency and Failure at Single-Cell Resolution |
$2,499,738 |
| University of California, Los Angeles | Kitai Kim | Foundational Mapping of Splicing-Derived Neoantigen Recognition in Human Sarcoma Using Stem Cell-Enabled Immune Platforms |
$2,500,000 |
| University of California, San Francisco | Dr. Neel S Singhal M.D. | Uncovering disease and cell-type-specific constraints on therapeutic delivery using a human CNS tissue discovery platform |
$2,500,000 |
| University of California, Los Angeles | Dr. Aya Barzelay Wollman | Mapping Human Retinal Niches to Improve Stem-Cell Therapy for Geographic Atrophy |
$2,500,000 |
| University of California, San Francisco | James Bayrer | Impact of Sex-Differences on Intestinal Stem Cell Function in Pediatric Inflammatory Bowel Disease |
$2,499,999 |
| University of Southern California | Dr. Lu Wang | A precision organoid platform to investigate APOE4 dependent cerebrovascular impairments |
$2,500,000 |
| University of California, San Francisco | Tomasz Nowakowski | Leveraging lessons from normal development to overcome barriers to efficient transplantation of stem cell derived cortical neurons. |
$2,500,000 |
| University of California, San Diego | Professor Alysson R Muotri | Allelic Expression States as Determinants of Neurodevelopmental Disorder Risk |
$2,500,000 |
| University of California, San Francisco | Yin Shen PhD | Systematic cell-type-resolved single-base resolution functional characterization of neurodevelopmental risk genes |
$2,500,000 |
