Stanford University

Awards to the Institution

Program	Investigator	Award Title	Award Value
Tools and Technologies III	Irving Weissman	Identification and isolation of transplantable human hematopoietic stem cells from pluripotent cell lines; two steps from primitive hematopoiesis to transplantable definitive cells, and non-toxic conditioning of hosts for hematopoeitic stem cell transp...	$1,271,952
New Cell Lines	Michele Calos	Safe, efficient creation of human induced pluripotent stem cells without the use of retroviruses	$1,406,875
Inception - Discovery Stage Research Projects	Philip Beachy	Curing bladder cancer by replacing corrupted urothelium with differentiated hES cells	$210,906
SEED Grant	Kenneth Weinberg	Embryonic stem cell-derived thymic epithelial cells	$628,793
Conference	Fan Yang	2014 Materials Research Society (MRS) Spring Meeting: Symposium Y: Biomaterials for Biomolecule Delivery and Understanding Cell-Niche Interactions	$10,000
Comprehensive Grant	Irving Weissman	Prospective isolation of hESC-derived hematopoietic and cardiomyocyte stem cells	$2,471,386
Patent Assistance Fund Awards	Katharine Ku	Funding for Patent Applications for CIRM-funded Inventions out of Stanford University	$3,525
Shared Labs	Vittorio Sebastiano	The Stanford University Center for Human Embryonic Stem Cell Research and Education	$3,434,600
Inception - Discovery Stage Research Projects	Guillem Pratx	Novel metabolic labeling method for tracking stem cells to irradiated salivary glands using PET	$229,227
New Faculty I	Karl Deisseroth	Bioengineering technology for fast optical control of differentiation and function in stem cells and stem cell progeny	$2,424,209
Quest - Discovery Stage Research Projects	Katja Weinacht	Regenerative Thymic Tissues as Curative Cell Therapy for Patients with 22q11 Deletion Syndrome	$1,251,720
Basic Biology III	Michael Clarke	USP16 controls stem cell number: implications for Down Syndrome	$1,263,826
Discovery Research Projects	Helen Blau	Application of PGE2/BPV, a muscle stem cell targeting therapeutic, to the treatment of COVID-19 associated diaphragm atrophy	$149,996
Training Grant I-1	Michael Longaker	Stanford CIRM Training Program	$3,035,282
Basic Biology IV	Roel Nusse	Asymmetric stem cell division oriented by a local self-renewing signal	$1,039,058
Tissue Collection for Disease Modeling	Joachim Hallmayer	Induced pluripotent stem cells from children with autism spectrum disorders	$530,265
Basic Biology V	Gary Steinberg	Paracrine and synaptic mechanisms underlying neural stem cell-mediated stroke recovery	$1,178,370
Basic Biology II	Steven Artandi	Self-renewal and senescence in iPS cells derived from patients with a stem cell disease	$931,285
Tools and Technologies III	Joseph Wu	Macaca mulatta as advanced model for predictive preclinical testing of engineered cardiac autografts and allografts	$1,689,744
New Cell Lines	Michael Longaker	Derivation and analysis of pluripotent stem cell lines with inherited TGF-b mediated disorders from donated IVF embryos and reprogrammed adult skin fibroblasts	$1,406,636
Inception - Discovery Stage Research Projects	Jeffrey Goldberg	Embryonic Stem Cells for Corneal Endothelial Degeneration	$235,836
SEED Grant	Joseph Wu	In Vivo Imaging of Human Embryonic Stem Cell Derivatives and Tumorigenicity	$623,634
Conference	Joseph Wu	Cardiovascular Regenerative Medicine Symposium	$9,000
Comprehensive Grant	Stefan Heller	Generation of inner ear sensory cells from human ES cells toward a cure for deafness	$2,330,371
Inception - Discovery Stage Research Projects	Helen Blau	Prodrug innovation to target muscle stem cells and enhance muscle regeneration	$235,834
Tools and Technologies I	Helen Blau	Regulation of Stem Cell Fate in Bioengineered Arrays of Hydrogel Microwells	$949,608
Inception - Discovery Stage Research Projects	Hiromitsu Nakauchi	Optimizing self-renewal signaling kinetics to stabilize ex vivo hematopoietic stem cell expansion	$210,906
New Faculty I	Joanna Wysocka	Trithorax and Polycomb methyltransferase complexes in cell fate determination.	$2,373,903
Quest - Discovery Stage Research Projects	Philip Beachy	Pluripotent stem cell-derived bladder epithelial progenitors for definitive cell replacement therapy of bladder cancer	$1,265,436
Basic Biology III	Aaron Hsueh	Correlated time-lapse imaging and single cell molecular analysis of human embryo development	$1,259,733
Discovery Research Projects	Albert Wong	Identifying HLA Class I Restricted Peptides That Induce CD8+ T Cells Against SARS-CoV-2	$249,999
Early Translational III	Joseph Wu	Heart Repair with Human Tissue Engineered Myocardium	$4,396,738
Basic Biology IV	Anne Brunet	Energy metabolism and aging pathways in human stem cell reprogramming and differentiation	$1,414,044
Tissue Collection for Disease Modeling	Joseph Wu	Tissue Collection for Accelerating iPSC Research in Cardiovascular Diseases	$1,291,832
Major Facilities	John Hennessy	Stanford SIM1 Building	$43,578,000
Basic Biology II	Garry Nolan	Kinase signaling analysis of iPS cell reprogramming and differentiation	$1,343,100
Preclinical Development Awards	Matthew Porteus	Pre-clinical development of gene correction therapy of hematopoietic stem cells for SCID-X1	$874,877
New Cell Lines	Renee Reijo Pera	Derivation and comparative analysis of human pluripotent ESCs, iPSCs and SSCs: Convergence to an embryonic phenotype	$1,409,243
Quest - Discovery Stage Research Projects	Hiromitsu Nakauchi	Novel Rejuvenated T Cell Immunotherapy for Lung Cancer	$1,968,456
SEED Grant	Joanna Wysocka	Role of Chromatin Modifiers in Regulating Human Embryonic Stem Cell Pluripotency	$629,952
Conference	Thomas Rando	Keystone Symposia, 'The Life of a Stem Cell: From Birth to Death'	$50,000
Comprehensive Grant	Roel Nusse	Guiding the developmental program of human embryonic stem cells by isolated Wnt factors	$1,710,462
Quest - Discovery Stage Research Projects	Mark Mercola	Multipotent Cardiovascular Progenitor Regeneration of the Myocardium after MI	$1,809,234
Transplantation Immunology	Christopher Contag	Engineering Embryonic Stem Cell Allografts for Operational Tolerance	$1,411,338
Quest - Discovery Stage Research Projects	Helen Blau	Stimulating endogenous muscle stem cells to counter muscle atrophy	$2,198,687
Tools and Technologies II	Michele Calos	Site-specific integration of Lmx1a, FoxA2, & Otx2 to optimize dopaminergic differentiation	$1,592,897
Quest - Discovery Stage Research Projects	Alan Cheng	Modulation of the Wnt pathway to restore inner ear function	$1,394,870
Basic Biology III	Joanna Wysocka	Enhancer-mediated gene regulation during early human embryonic development	$1,420,618
Early Translational III	Helen Blau	Local Delivery of Rejuvenated Old Muscle Stem Cells to Increase Strength in Aged Patients	$1,825,666
Basic Biology IV	Michael Cleary	Prostaglandin pathway regulation of self-renwal in hematopoietic and leukemia stem cells	$1,244,455
Early Translational IV	Michele Calos	Engineered iPSC for therapy of limb girdle muscular dystrophy type 2B	$1,876,253
Disease Team Planning	Robert Robbins	{REDACTED} Cardiovascular Regenerative Team	$25,119
Basic Biology II	Aaron Hsueh	Maturation of Human Oocytes for SCNT and Embryonic Stem Cell Derivation	$1,309,018
SPARK	Paul Utz	Stem Cell and Regenerative Medicine- Summer Research Internship	$384,110
SEED Grant	Krishna Shenoy	Technology for hESC-Derived Cardiomyocyte Differentiation and Optimization of Graft-Host Integration in Adult Myocardium	$572,891
Quest - Discovery Stage Research Projects	Rosa Bacchetta	GENE EDITING FOR FOXP3 IN HUMAN HSC	$984,228
SEED Grant	Phillip Yang	In Vivo Molecular Magnetic Resonance Imaging of Human Embryonic Stem Cells in Murine Model of Myocardial Infarction	$629,952
Conference	Hank Greely	Stem Cell Policy: Understanding the Scientific and Legal Challenges Ahead	$5,838
Comprehensive Grant	Julie Baker	Functional Genomic Analysis of Chemically Defined Human Embryonic Stem Cells	$2,518,303
Conference II	Samuel Strober	Third International Workshop on Clinical Tolerance	$29,500
Transplantation Immunology	Robert Negrin	Regulatory T cell induced tolerance to ESC transplantation	$1,382,658
Quest - Discovery Stage Research Projects	Kyle Loh	Towards hepatocyte cell replacement therapy: developing a renewable source of human hepatocytes from pluripotent stem cells	$1,968,456
Tools and Technologies II	Theo Palmer	Development of small molecule screens for autism using patient-derived iPS cells	$1,797,606
Therapeutic Translational Research Projects	Theodore Leng	NeuBright, a purified allogeneic cell therapy product for treatment of Dry Age-related Macular Degeneration	$4,235,758
Basic Biology III	Sean Wu	Elucidating Molecular Basis of Hypertrophic Cardiomyopathy with Human Induced Pluripotent Stem Cells	$1,260,537
Early Translational III	Bertha Chen	Autologous iPSC Therapy for Urinary Incontinence	$4,715,738
Basic Biology IV	Alexander Dunn	Role of mechanical signaling in stem cell self-renewal and differentiation	$1,062,998
Disease Team Therapy Development III	Irving Weissman	Clinical Investigation of a Humanized Anti-CD47 Antibody in Targeting Cancer Stem Cells in Hematologic Malignancies and Solid Tumors	$6,505,568
Shared Labs	Renee Reijo Pera	The Stanford University Center for Human Embryonic Stem Cell Research and Education	$2,439,590
Early Translational II	Michele Calos	Stem Cell Therapy for Duchenne Muscular Dystrophy	$2,267,261
Therapeutic Translational Research Projects	Albert Wong	2nd Generation Vaccine for the Treatment of Glioblastoma	$2,929,889
SEED Grant	Calvin Kuo	Differentiation of Human Embryonic Stem Cells to Intestinal Fates	$554,176
Quest - Discovery Stage Research Projects	Roel Nusse	Preclinical development of human hepatocyte progenitor cells for cell therapy	$1,651,211
SEED Grant	Susan McConnell	Optimization of guidance response in human embryonic stem cell derived midbrain dopaminergic neurons in development and disease	$607,363
Conference	Joseph Wu	Cardiovascular Tissue Engineering Symposium	$25,000
Comprehensive Grant	Theo Palmer	Immunology of neural stem cell fate and function	$2,396,000
Late Stage Preclinical Projects	Gary Steinberg	Intraparenchymal NR1 Stem Cell Therapy for Chronic Subcortical Ischemic Stroke	$5,300,000
Transplantation Immunology	Judith Shizuru	Purified allogeneic hematopoietic stem cells as a platform for tolerance induction	$1,233,275
Conference II	Joseph Wu	2018 Stanford Drug Discovery and Stem Cell Technology Conference	$15,000
Tools and Technologies II	Sarah Heilshorn	Preparation and Delivery of Clinically Relevant Numbers of Stem Cells Using 3D Hydrogels	$600,695
Clinical Trial Stage Projects	Everett Meyer	Induction of Tolerance by Combinatorial Therapy w/ Donor Stem Cells and Expanded Recipient Treg cells in HLA-mismatched Kidney Transplant Recipients	$11,955,585
Research Training II	Theo Palmer	Stanford CIRM Training Program	$7,017,629
Disease Team Therapy Development - Research	Judith Shizuru	A monoclonal antibody that depletes blood stem cells and enables chemotherapy free transplants	$19,068,382
Basic Biology IV	Michelle Monje	Stem Cell Mechanisms Governing Discrete Waves of Gliogenesis in the Childhood Brain	$1,264,248
Research Leadership	Hiromitsu Nakauchi	Generation of functional cells and organs from iPSCs	$5,427,358
Genomics Centers of Excellence Awards (R)	Michael Snyder	Center of Excellence for Stem Cell Genomics - Stanford	$22,787,914
Disease Team Research I	Alfred Lane	iPS Cell-Based Treatment of Dominant Dystrophic Epidermolysis Bullosa	$11,039,208
Conference II	Joseph Wu	Drug Discovery & Stem Cell Models for Cardiovascular Disease Conference	$7,500
SEED Grant	John Cooke	EC regeneration in cerebrovascular ischemia: role of NO	$476,995
Quest - Discovery Stage Research Projects	Matthew Porteus	Genome Editing to Correct Cystic Fibrosis Mutations in Airway Stem Cells	$1,968,456
SEED Grant	Mark Kay	Novel vectors for gene transfer into human ES cells	$574,737
Clinical Trial Stage Projects	Samuel Strober	Induction of Tolerance to Combined Kidney and Hematopoietic Progenitor Cell Transplants from HLA Haplotype Matched Living Donors	$6,653,266
Comprehensive Grant	Christopher Zarins	Engineering a Cardiovascular Tissue Graft from Human Embryonic Stem Cells	$2,454,490
Disease Team Planning	Thomas Rando	Stem Cell Therapy for Muscular Dystrophy	$0
Transplantation Immunology	Kenneth Weinberg	Engineered immune tolerance by Stem Cell-derived thymic regeneration	$1,271,729
Tools and Technologies III	James Dunn	Skin-derived precursor cells for the treatment of enteric neuromuscular dysfunction	$772,098
Tools and Technologies II	Brian Rutt	Development of Single Cell MRI Technology using Genetically-Encoded Iron-Based Reporters	$1,833,348
Clinical Trial Stage Projects	Judith Shizuru	A monoclonal antibody that depletes blood stem cells and enables chemotherapy free transplants	$3,426,902
Disease Team Therapy Planning I	Judith Shizuru	A monoclonal antibody that depletes blood stem cells and enables chemotherapy free transplants	$90,147
Disease Team Therapy Development - Research	Joseph Wu	Human Embryonic Stem Cell-Derived Cardiomyocytes for Patients with End Stage Heart Failure	$19,060,330
Creativity Awards	Paul Utz	SIMR Program: Stem Cell & Developmental Biology Research Internships	$340,611
Basic Biology V	Xinnan Wang	Misregulated Mitophagy in Parkinsonian Neurodegeneration	$1,174,943
Basic Biology I	Susan McConnell	Identification and characterization of human ES-derived DA neuronal subtypes	$1,404,853
Tools and Technologies III	Anthony Oro	A Chromatin Context Tool for Predicting iPS Lineage Predisposition and Tissue Graftability	$1,391,125
Disease Team Research I	Gary Steinberg	Embryonic-Derived Neural Stem Cells for Treatment of Motor Sequelae following Sub-cortical Stroke	$17,244,851
Disease Team Research I	Irving Weissman	Development of Therapeutic Antibodies Targeting Human Acute Myeloid Leukemia Stem Cells	$18,759,276
Inception - Discovery Stage Research Projects	Phillip Yang	Activation of patient-specific endogenous myocardial repair through the exosomes generated from the hypoxic iPSC-derived cardiomyocytes (iCMs).	$234,619
SEED Grant	Aaron Hsueh	Patient-specific cells with nuclear transfer	$629,653
Conference	Julien Sage	3rd International RB conference	$10,000
SEED Grant	Julien Sage	Functions of RB family proteins in human embryonic stem cells	$498,609
Tool Translational Research Projects	Joseph Wu	A Novel, Robust and Comprehensive Predictive Tool Using Human Disease-Specific Induced Pluripotent Stem Cells for Preclinical Drug Screening	$975,000
Comprehensive Grant	Renee Reijo Pera	Human oocyte development for genetic, pharmacological and reprogramming applications	$2,298,411
Late Stage Preclinical Projects	Matthew Porteus	Genome Editing of Autologous Hematopoietic Stem Cells to Treat Sickle Cell Disease	$4,849,363
New Faculty I	Anne Brunet	Molecular mechanisms involved in adult neural stem cell maintenance	$2,348,435
Clinical Trial Stage Projects	Crystal Mackall	Phase 1 Study of CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells in Adults with Recurrent or Refractory B Cell Malignancies	$11,034,982
Tools and Technologies II	Irving Weissman	Antibody tools to deplete or isolate teratogenic, cardiac, and blood stem cells from hESCs	$1,463,814
Late Stage Preclinical Projects	Rosa Bacchetta	IND-enabling activities for a Phase 1 Study of Autologous CD4LVFOXP3 T Cells in Subjects with IPEX Syndrome	$5,002,496
Disease Team Therapy Planning I	Albert Wong	Recombinant Bispecific Antibody Targeting Cancer Stem Cells for the Therapy of Glioblastoma	$109,750
Basic Biology IV	Howard Chang	Long noncoding RNAs for pluripotency and cell fate commitment	$1,386,627
New Faculty Physician Scientist	Alan Cheng	Enhancing hair cell regeneration in mouse and human inner ear	$3,088,525
Basic Biology V	Helen Blau	Mass Cytometry to Delineate the Human Muscle Stem Cell Hierarchy and Dysfunction in Aging	$1,175,357
Basic Biology I	Julien Sage	The retinoblastoma (RB) gene family in cellular reprogramming	$1,357,085
Tools and Technologies III	Fan Yang	Injectable Macroporous Matrices to Enhance Stem Cell Engraftment and Survival	$1,434,235
New Cell Lines	Julie Baker	Derivation of hESC Lines with Disease Lesions	$1,404,725
Inception - Discovery Stage Research Projects	Bertha Chen	Autologous iPSC-based therapy for radiation induced bladder injury	$235,836
SEED Grant	Thomas Wandless	Reprogramming Differentiated Human Cells to a Pluripotent State	$380,005
Conference	Thomas Rando	Third Annual Symposium on Regenerative Rehabilitation	$20,000
New Faculty II	Ching-Pin Chang	VEGF signaling in adventitial stem cells in vascular physiology and disease	$3,005,695
Conference II	Joseph Wu	2017 Stanford Drug Discovery and Stem Cell Technology Conference	$2,359
Early Translational I	Jill Helms	Enhancing healing via Wnt-protein mediated activation of endogenous stem cells	$6,464,126
Therapeutic Translational Research Projects	Anthony Oro	DEBCT: Genetically Corrected, Induced Pluripotent Cell-Derived Epithelial Sheets for Definitive Treatment of Dystrophic Epidermolysis Bullosa	$5,107,353
New Faculty I	Howard Chang	Noncoding RNAs in Cell Fate Determination	$2,985,894
Therapeutic Translational Research Projects	Bertha Chen	Autologous iPSC-derived smooth muscle cell therapy for treatment of urinary incontinence	$5,977,155
Tools and Technologies II	Marius Wernig	Cellular tools to study brain diseases affecting synaptic transmission	$1,664,382
Progression Award - Discovery Stage Research Projects	Hiromitsu Nakauchi	Using metabolic pausing for maintaining stable and high-quality pluripotent stem cells	$208,422
Disease Team Therapy Planning I	Robert Robbins	Human Embryonic Stem Cell-Derived Cardiomyocytes for Patients with End Stage Heart Failure	$73,030
Basic Biology IV	Gerald Crabtree	Mechanism and Utility of Direct Neuronal Conversion with a MicroRNA-Chromatin Switch	$1,392,150
New Faculty Physician Scientist	Michelle Monje	White matter neuroregeneration after chemotherapy: stem cell therapy for “chemobrain”	$2,800,526
Basic Biology V	Marius Wernig	Mechanisms of human induced neuronal cell reprogramming	$1,178,370
Basic Biology I	Helen Blau	Molecular Mechanisms of Reprogramming towards Pluripotency	$1,408,332
Tools and Technologies III	Sarah Heilshorn	Injectable Hydrogels for the Delivery, Maturation, and Engraftment of Clinically Relevant Numbers of Human Induced Pluripotent Stem Cell-Derived Neural Progenitors to the Central Nervous System	$1,347,767
			Total: $388,179,444.00