All CIRM Grants

Institution Researcher name Grant Type Grant Title Award Value
University of California, Los Angeles Dana Jones New Faculty I Characterization of mechanisms regulating de-differentiation and the re-acquisition of stem cell identity $382,773
Scripps Research Institute Martin Friedlander Early Translational I Autologous Retinal Pigmented Epithelial Cells Derived from Induced Pluripotent Stem Cells for the Treatment of Atrophic Age Related Macular Degeneration $5,866,528
University of California, San Diego Anirvan Ghosh SEED Grant Generation of forebrain neurons from human embryonic stem cells $587,591
University of Southern California Mohammad Pashmforoush New Faculty I Transcriptional Regulation of Cardiac Pacemaker Cell Progenitors $27,949
Salk Institute for Biological Studies Fred Gage Early Translational II Crosstalk: Inflammation in Parkinson’s disease (PD) in a humanized in vitro model $2,472,839
University of California, Berkeley Andrew Dillin Basic Biology V A Requirement for Protein Homeostasis in the Mediation of Stem Cell Health $1,034,100
University of California, San Diego Shu Chien Tools and Technologies II Development of Synthetic Microenvironments for Stem Cell Growth and Differentiation $1,706,628
Stanford University Gerald Crabtree Basic Biology IV Mechanism and Utility of Direct Neuronal Conversion with a MicroRNA-Chromatin Switch $1,392,426
Sanford-Burnham Medical Research Institute Ziwei Huang SEED Grant New Chemokine-Derived Therapeutics Targeting Stem Cell Migration $708,000
University of California, Los Angeles Zack Jerome New Cell Lines Generation of clinical grade human iPS cells $1,341,000
Buck Institute for Age Research Mary McEachron Major Facilities CIRM Center of Excellence at Buck Institute for Age Research $20,500,000
Stanford University Marius Wernig Tools and Technologies II Cellular tools to study brain diseases affecting synaptic transmission $1,664,382
University of California, Berkeley David Schaffer Tools and Technologies I Directed Evolution of Novel AAV Variants for Enhanced Gene Targeting in Pluripotent Human Stem Cells and Investigation of Dopaminergic Neuron Differentiation $918,000
University of California, Los Angeles Owen Witte Basic Biology IV Trop2 dependent and independent mechanisms of self-renewal in human cancer stem cells $1,254,960
Stanford University Ching-Pin Chang New Faculty II VEGF signaling in adventitial stem cells in vascular physiology and disease $3,005,695
Samumed, LLC John Hood Disease Team Therapy Planning I Clinical Development of an osteoinductive therapy to prevent osteoporosis-related fractures $99,110
University of California, San Diego Binhai Zheng SEED Grant Genetic manipulation of human embryonic stem cells and its application in studying CNS development and repair $600,441
Salk Institute for Biological Studies Samuel Pfaff Disease Team Planning Motor neuron diseases: Finding cures through basic, translational, and clinical collaboration $54,016
University of California, San Diego Karl Willert Basic Biology I WNT signaling and the control of cell fate decisions in human pluripotent stem cells. $1,329,298
Stanford University Joachim Hallmayer Tissue Collection for Disease Modeling Induced pluripotent stem cells from children with autism spectrum disorders $530,265
Scripps Research Institute Jeanne Loring Tools and Technologies I The Stem Cell Matrix: a map of the molecular pathways that define pluripotent cells $1,133,552
University of California, Irvine Peter Donovan Comprehensive Grant Improved hES Cell Growth and Differentiation $2,381,713
University of California, Irvine Peter Bryant Training Grant I-1 Stem Cell Research Training Grant $1,935,487
University of Southern California David Hinton SEED Grant Therapeutic potential of Retinal Pigment Epithelial cell lines derived from hES cells for retinal degeneration. $651,607
University of California, Los Angeles Stanley Carmichael Disease Team Planning Development of a Stem Cell Therapy to Promote Functional Recovery in Stroke $42,748
Sanford-Burnham Medical Research Institute Huei-sheng Chen Basic Biology II Endothelial cells and ion channel maturation of human stem cell-derived cardiomyocytes $1,587,610
La Jolla Institute for Allergy and Immunology Anjana Rao Transplantation Immunology Generation of regulatory T cells by reprogramming $1,464,446
University of California, Irvine Hans Keirstead Comprehensive Grant hESC-Derived Motor Neurons For the Treatment of Cervical Spinal Cord Injury $2,158,445
University of California, San Diego Eric Adler Early Translational III Identification of Novel Therapeutics for Danon Disease Using an iPS Model of the Disease $1,701,575
University of California, San Francisco Valerie Weaver SEED Grant Force, Dimensionality and Stem Cell Fate $529,762
University of California, Los Angeles Shuo Lin Basic Biology III Etsrp/ER71 mediated stem cell differentiation into vascular lineage $1,382,400
University of California, Irvine Peter Donovan Shared Labs Regional Human Embryonic Stem Cell Shared Research Laboratory and Stem Cell Techniques Course $2,107,376
University of California, Davis Mark Zern Early Translational II Liver Cell Transplantation $4,215,748
University of California, Los Angeles Siavash Kurdistani New Faculty I Epigenetics in cancer stem cell initiation and clinical outcome prediction $3,063,450
Gladstone Institutes Warner Greene Early Translational I Maximizing the Safety of Induced Pluripotent Stem Cells as an Infusion Therapy: Limiting the Mutagenic Threat of Retroelement Retrotransposition during iPSC Generation, Expansion and Differentiation $1,324,011
University of California, Irvine Brian Cummings SEED Grant The Immunological Niche: Effect of immunosuppressant drugs on stem cell proliferation, gene expression, and differentiation in a model of spinal cord injury. $595,345
University of California, San Diego Dennis Carson Disease Team Research I Development of Highly Active Anti-Leukemia Stem Cell Therapy (HALT) $19,999,826
University of California, San Diego Miles Wilkinson Basic Biology V New Regulators of Spermatogonial Stem Cells: RHOX Homeobox Transcription Factors $560,160
University of California, San Diego Ananda Goldrath Basic Biology IV Mechanisms to protect hESC-derived cells from allogenic immune rejection $1,161,000
Stanford University Mark Kay SEED Grant Novel vectors for gene transfer into human ES cells $574,737
Sanford-Burnham Medical Research Institute Zhuohua Zhang New Cell Lines Derivation of Parkinson's Disease Coded-Stem Cells (PD-SCs) $1,556,448
Sanford Consortium for Regenerative Medicine Edward Holmes Major Facilities Sanford Consortium for Regenerative Medicine $42,827,439
University of California, San Diego Karl Willert Tools and Technologies II Homologous recombination in human pluripotent stem cells using adeno-associated virus. $1,659,043
University of California, Los Angeles Hsian-Rong Tseng Tools and Technologies I Microfluidic Platform for Screening Chemically Defined Conditions that Facilitate Clonal Expansion of Human Pluripotent Stem Cells $914,096
University of California, San Diego David Traver Basic Biology IV DECIPHERING THE INSTRUCTIONS FOR VERTEBRATE HSC SPECIFICATION AND AMPLIFICATION. $1,363,698
University of California, San Diego Catriona Jamieson New Faculty II Derivation and Characterization of Myeloproliferative Disorder Stem Cells from Human ES Cells $3,065,572
Sanford-Burnham Medical Research Institute Stuart Lipton Disease Team Therapy Planning I hESC-derived NPCs Programmed with MEF2C for Cell Transplantation in Parkinson’s Disease $96,448
University of California, Berkeley Carolyn Bertozzi SEED Grant Profiling surface glycans and glycoprotein expression of human embryonic stem cells $444,847
Gladstone Institutes Deepak Srivastava Disease Team Planning Pluripotent Stem Cell–Based Therapy for Heart Disease $13,505
University of California, Los Angeles Robb Maclellan Basic Biology I Human Cardiovascular Progenitors, their Niches and Control of Self-renewal and Cell Fate $917,667
University of California, Irvine Orhan NALCIOGLU Tools and Technologies I A Multimodality Molecular Imaging Systen (MRSPECT) for in Vivo Stem Cell Tracking $719,798
University of California, San Francisco Andrew Leavitt Comprehensive Grant Understanding hESC-based Hematopoiesis for Therapeutic Benefit $2,460,822
Scripps Research Institute Peter Schultz Training Grant I-2 Training Grant I $1,021,395
University of California, Irvine Michelle Khine SEED Grant Micro Platform for Controlled Cardiac Myocyte Differentiation $156,426
University of California, Merced Michelle Khine SEED Grant Micro Platform for Controlled Cardiac Myocyte Differentiation $194,371
University of California, San Francisco John Rubenstein Basic Biology II MGE Enhancers to Select for Interneuron Precursors Produced from Human ES Cells $1,387,800
University of California, Berkeley David Raulet Transplantation Immunology Inactivating NK cell reactivity to facilitate transplantation of stem cell derived tissue $952,896
University of California, San Francisco Arnold Kriegstein Comprehensive Grant Derivation of Inhibitory Nerve Cells from Human Embryonic Stem Cells $2,410,874
University of Southern California Toshio Miki Early Translational III Generation of hepatic cell from placental stem cell for congenital metabolic disorders $1,750,375
Sanford-Burnham Medical Research Institute Alexey Terskikh SEED Grant Analysis of Candidate Neural Crest Cells Derived from Human ES Cells $703,684
Scripps Research Institute Kristin Baldwin Basic Biology III Identifying sources of mutation in human induced pluripotent stem cells by whole genome sequencing $1,705,500
University of California, Santa Barbara Dennis Clegg Shared Labs Laboratory for Stem Cell Biology and Engineering $1,407,192
University of California, Los Angeles Dennis Slamon Disease Team Therapy Development III A Phase I dose escalation and expansion clinical trial in patients with advanced solid tumors $6,924,317
University of California, Merced Jennifer Manilay New Faculty I Enhancing Survival of Embryonic Stem Cell-Derived Grafts by Induction of Immunological Tolerance $1,576,404
Jackson Laboratory West Pali Kaur Early Translational I Mouse Models for Stem Cell Therapeutic Development $3,759,134
University of California, Davis Vicki Wheelock Disease Team Therapy Development - Research MSC engineered to produce BDNF for the treatment of Huntington's disease $17,857,797
Sanford-Burnham Medical Research Institute Hudson Freeze SEED Grant Role of Glycans in Human Embryonic Stem Cell Conversion to Neural Precursor Cells $708,000
University of California, Davis Frederick Meyers Research Training II Stem Cell Training Program $5,822,412
Stanford University Theo Palmer Tools and Technologies II Development of small molecule screens for autism using patient-derived iPS cells $1,797,606
Stanford University Julien Sage SEED Grant Functions of RB family proteins in human embryonic stem cells $498,609
University of California, Davis Laura Marcu Tools and Technologies III Multimodal platform combining optical and ultrasonic technologies for in vivo nondestructive evaluation of engineered vascular tissue constructs $1,834,474
Stanford University Julie Baker New Cell Lines Derivation of hESC Lines with Disease Lesions $1,404,725
Stanford University John Hennessy Major Facilities Stanford SIM1 Building $43,578,000
Fluidigm Corporation Marc Unger Tools and Technologies I Scaleup of Versatile, Fully Automated, Microfluidic Cell Culture System $749,518
Cedars-Sinai Medical Center Clive Svendsen Disease Team Therapy Planning I Stem Cells Secreting GDNF for the Treatment of ALS $63,487
Stanford University Krishna Shenoy SEED Grant Technology for hESC-Derived Cardiomyocyte Differentiation and Optimization of Graft-Host Integration in Adult Myocardium $572,891
ViaCyte, Inc. Emmanuel Baetge Disease Team Planning Development of a Cell Replacement Therapy Product for Insulin Dependent Diabetes $48,950
University of California, Davis Min Zhao Basic Biology I Directing migration of human stem cells with electric fields $816,228
University of California, Los Angeles Michael Phelps Tools and Technologies I Novel Tools and Technologies for Translational PET Imaging of Cell-based Therapies $914,039
University of California, Irvine Douglas Wallace Comprehensive Grant The Dangers of Mitochondrial DNA Heteroplasmy in Stem Cells Created by Therapeutic Cloning $1,790,133
Gladstone Institutes Robert Mahley Training Grant I-2 Gladstone CIRM Scholar Program $2,192,073
University of California, Riverside Frank Sauer SEED Grant Non-coding RNA as tool for the active control of stem cell differentiation $571,650
University of California, San Diego Deborah Spector Basic Biology III Viral-host interactions affecting neural differentiation of human progenitors $1,372,660
Children's Hospital of Los Angeles Barbara Des Rochers Comprehensive Grant Regulated Expansion of Lympho-hematopoietic Stem and Progenitor Cells from Human Embryonic Stem Cells (hESC) $575,994
Salk Institute for Biological Studies Inder Verma Early Translational IV Development of a cell and gene based therapy for hemophilia $2,298,634
University of California, Berkeley Ellen Robey Transplantation Immunology Human Immune System Mouse models as preclinical platforms for stem cell derived grafts $1,005,605
Stanford University Renee Reijo Pera Comprehensive Grant Human oocyte development for genetic, pharmacological and reprogramming applications $2,298,411
University of California, San Francisco Arnold Kriegstein Early Translational III Human ES cell-derived MGE inhibitory interneuron transplantation for spinal cord injury $1,623,251
Salk Institute for Biological Studies Beverly Emerson SEED Grant Regulation of Specific Chromosomal Boundary Elements by CTCF Protein Complexes in Human Embryonic Stem Cells $647,343
University of California, San Francisco John Murnane Basic Biology III Genomic instability during culturing of human embryonic stem cells $1,070,919
University of California, San Diego Karl Willert Shared Labs Enhancing Facilities for Genetic Manipulation and Engineering of Human Embryonic Stem Cells $1,728,080
University of California, San Diego Catriona Jamieson Early Translational II Preclinical development of a pan Bcl2 inhibitor for cancer stem cell directed therapy $3,103,041
University of California, Los Angeles Hanna Mikkola New Faculty I Mechanisms of Hematopoietic stem cell Specification and Self-Renewal $2,286,900
Parkinson's Institute J. William Langston Early Translational I Using patient-specific iPSC derived dopaminergic neurons to overcome a major bottleneck in Parkinson's disease research and drug discovery $3,698,646
University of Southern California Qilong Ying SEED Grant Self-renewal of human embryonic stem cells $621,421
University of California, Los Angeles Richard Gatti Tools and Technologies II Use of hiPSCs to develop lead compounds for the treatment of genetic diseases $1,833,054
University of California, Riverside Prudence Talbot Shared Labs A Stem Cell Core Facility for Studying Human Embryonic Stem Cell Differentiation $1,679,818
University of California, San Diego Eugene Yeo Basic Biology IV Stem cell models to analyze the role of mutated C9ORF72 in neurodegeneration $1,260,360
Scripps Research Institute Peter Schultz SEED Grant A Chemical Approach to Stem Cell Biology $748,944
Stanford University Michele Calos New Cell Lines Safe, efficient creation of human induced pluripotent stem cells without the use of retroviruses $1,406,875

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