Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
Retina Organoid Transplants Develop Photoreceptors and Improve Visual Function in RCS Rats With RPE Dysfunction. 2020 Invest Ophthalmol Vis Sci
Immune-evasive human islet-like organoids ameliorate diabetes. 2020 Nature
Functionally heterogeneous human satellite cells identified by single cell RNA sequencing. 2020 Elife
Lentiviral gene therapy for X-linked chronic granulomatous disease. 2020 Nat Med
Busulfan Pharmacokinetics in Adenosine Deaminase-Deficient Severe Combined Immunodeficiency Gene Therapy. 2020 Biol Blood Marrow Transplant
Northstar enables automatic classification of known and novel cell types from tumor samples. 2020 Sci Rep
mTOR signaling regulates the morphology and migration of outer radial glia in developing human cortex. 2020 Elife
Loss of NARS1 impairs progenitor proliferation in cortical brain organoids and leads to microcephaly. 2020 Nat Commun
Stem Cells and Lung Regeneration. 2020 Am J Physiol Cell Physiol
Broad-spectrum antibiotics alter the microbiome, increase intestinal fxr, and decrease hepatic steatosis in zebrafish short bowel syndrome. 2020 Am J Physiol Gastrointest Liver Physiol
Post-Transcriptional Regulation of Homeostatic, Stressed, and Malignant Stem Cells. 2020 Cell Stem Cell
Multiexon deletion alleles of ATF6 linked to achromatopsia. 2020 JCI Insight
Splice Modulation Synergizes Cell Cycle Inhibition. 2020 ACS Chem Biol
A Human Skeletal Muscle Atlas Identifies the Trajectories of Stem and Progenitor Cells across Development and from Human Pluripotent Stem Cells. 2020 Cell Stem Cell
Three-dimensional bioprinted glioblastoma microenvironments model cellular dependencies and immune interactions. 2020 Cell Res
Articular cartilage regeneration by activated skeletal stem cells. 2020 Nat Med
Epithelial/mesenchymal heterogeneity of high-grade serous ovarian carcinoma samples correlates with miRNA let-7 levels and predicts tumor growth and metastasis. 2020 Mol Oncol
A Small-Molecule Wnt Mimic Improves Human Limbal Stem Cell Ex Vivo Expansion. 2020 iScience
Outcomes of Limbal Stem Cell Transplant: A Meta-analysis. 2020 JAMA Ophthalmol
Corneal Epithelial Thickness Measured Using Anterior Segment Optical Coherence Tomography as a Diagnostic Parameter for Limbal Stem Cell Deficiency. 2020 Am J Ophthalmol
Limbal Stem Cell Deficiency After Glaucoma Surgery. 2020 Cornea
Immunodeficient mice are better for modeling the transfusion of human blood components than wild-type mice. 2020 PLoS One
CRISPR-based gene editing enables FOXP3 gene repair in IPEX patient cells. 2020 Sci Adv
PAWI-2 overcomes tumor stemness and drug resistance via cell cycle arrest in integrin beta3-KRAS-dependent pancreatic cancer stem cells. 2020 Sci Rep
Clonal isolation of endothelial colony-forming cells from early gestation chorionic villi of human placenta for fetal tissue regeneration. 2020 World J Stem Cells
A Decade of Experience with the Ovine Model of Myelomeningocele: Risk Factors for Fetal Loss. 2020 Fetal Diagn Ther
Global Consensus on the Management of Limbal Stem Cell Deficiency. 2020 Cornea
Long-term outcomes of Descemet membrane endothelial keratoplasty in eyes with prior glaucoma surgery. 2020 Am J Ophthalmol
Manufacturing considerations for producing and assessing decellularized extracellular matrix hydrogels. 2020 Methods
Dose optimization of decellularized skeletal muscle extracellular matrix hydrogels for improving perfusion and subsequent validation in an aged hindlimb ischemia model. 2020 Biomater Sci
Unleashing the cure: Overcoming persistent obstacles in the translation and expanded use of hematopoietic stem cell-based therapies. 2020 Stem Cells Translational Medicine
Aberrant Development Corrected in Adult-Onset Huntington's Disease iPSC-Derived Neuronal Cultures via WNT Signaling Modulation. 2020 Stem Cell Reports
Long-term eradication of extranodal natural killer/T-cell lymphoma, nasal type, by induced pluripotent stem cell-derived Epstein-Barr virus-specific rejuvenated T cells in vivo. 2020 Haematologica
Germline development in rat revealed by visualization and deletion of Prdm14. 2020 Development
Compensation of Disabled Organogeneses in Genetically Modified Pig Fetuses by Blastocyst Complementation. 2020 Stem Cell Reports
Long-term ex vivo expansion of mouse hematopoietic stem cells. 2020 Nat Protoc
Resolving the 3D Landscape of Transcription-Linked Mammalian Chromatin Folding. 2020 Mol Cell
Adeno-Associated Virus and Hematopoietic Stem Cells: The Potential of Adeno-Associated Virus Hematopoietic Stem Cells in Genetic Medicines. 2020 Hum Gene Ther
A critical look: Challenges in differentiating human pluripotent stem cells into desired cell types and organoids. 2020 Wiley Interdiscip Rev Dev Biol
An engineered cell-laden adhesive hydrogel promotes craniofacial bone tissue regeneration in rats. 2020 Sci Transl Med
An intrinsic, label-free signal for identifying stem cell-derived cardiomyocyte subtype. 2020 Stem Cells
Fat grafting rescues radiation-induced joint contracture. 2020 Stem Cells
Guided nuclear exploration increases CTCF target search efficiency. 2020 Nat Chem Biol
Preliminary Results of a Phase 1/2 Clinical Study of Zinc Finger Nuclease-Mediated Editing of BCL11A in Autologous Hematopoietic Stem Cells for Transfusion-Dependent Beta Thalassemia 2019 Blood
Editing the Sickle Cell Disease Mutation in Human Hematopoietic Stem Cells: Comparison of Endonucleases and Homologous Donor Templates. 2019 Mol Ther
Systematic genetic analysis of the MHC region reveals mechanistic underpinnings of HLA type associations with disease. 2019 Elife
Wnt signaling inhibition by monensin results in a period of Hippo pathway activation during intestinal adaptation in zebrafish. 2019 Am J Physiol Gastrointest Liver Physiol
Effects of Spaceflight and Simulated Microgravity on YAP1 Expression in Cardiovascular Progenitors: Implications for Cell-Based Repair. 2019 Int J Mol Sci
Biomaterials for tissue repair. 2019 Science
Chasing Mavericks: The quest for defining developmental waves of hematopoiesis. 2019 Curr Top Dev Biol

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