Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
Novel Humanized Peripheral Blood Mononuclear Cell Mouse Model with Delayed Onset of Graft-versus-Host Disease for Preclinical HIV Research. 2022 J Virol
Human induced pluripotent stem cell-derived macrophages ameliorate liver fibrosis. 2021 Stem Cells
Mesenchymal Stromal Cells Regulate Sialylations of N-Glycans, Affecting Cell Migration and Survival. 2021 Int J Mol Sci
Retinal Organoids Long-Term Functional Characterization Using Two-Photon Fluorescence Lifetime and Hyperspectral Microscopy. 2021 Front Cell Neurosci
Multiple Treatment Cycles of Neural Stem Cell Delivered Oncolytic Adenovirus for the Treatment of Glioblastoma. 2021 Cancers (Basel)
Insulin expression and C-peptide in type 1 diabetes subjects implanted with stem cell-derived pancreatic endoderm cells in an encapsulation device. 2021 Cell Rep Med
Assessing Oximetry Response to Chimeric Antigen Receptor T-cell Therapy against Glioma with (19)F MRI in a Murine Model. 2021 Radiol Imaging Cancer
Metallofluorocarbon Nanoemulsion for Inflammatory Macrophage Detection via PET and MRI. 2021 J Nucl Med
Comparative transcriptomic analysis of SARS-CoV-2 infected cell model systems reveals differential innate immune responses. 2021 Sci Rep
Discovery and Mechanism of SARS-CoV-2 Main Protease Inhibitors. 2021 J Med Chem
In vitro safety "clinical trial" of the cardiac liability of drug polytherapy. 2021 Clin Transl Sci
Proangiogenic Collagen-Binding Glycan Therapeutic Promotes Endothelial Cell Angiogenesis. 2021 ACS Biomater Sci Eng
Heart Muscle Microphysiological System for Cardiac Liability Prediction of Repurposed COVID-19 Therapeutics. 2021 Front Pharmacol
Non-Invasive Prenatal Test for beta-Thalassemia and Sickle Cell Disease Using Probe Capture Enrichment and Next-Generation Sequencing of DNA in Maternal Plasma. 2021 J Appl Lab Med
Early-life inflammation primes a T helper 2 cell-fibroblast niche in skin. 2021 Nature
LONG-TERM IMMUNOLOGIC EFFECTS OF SARS-CoV-2 INFECTION: LEVERAGING TRANSLATIONAL RESEARCH METHODOLOGY TO ADDRESS EMERGING QUESTIONS. 2021 Transl Res
Doxycycline Significantly Enhances Induction of Induced Pluripotent Stem Cells to Endoderm by Enhancing Survival Through Protein Kinase B Phosphorylation. 2021 Hepatology
A bioinspired and chemically defined alternative to dimethyl sulfoxide for the cryopreservation of human hematopoietic stem cells. 2021 Bone Marrow Transplant
Co-grafts of Human Embryonic Stem Cell Derived Retina Organoids and Retinal Pigment Epithelium for Retinal Reconstruction in Immunodeficient Retinal Degenerate Royal College of Surgeons Rats. 2021 Front Neurosci
Preventing Engrailed-1 activation in fibroblasts yields wound regeneration without scarring. 2021 Science
Development of selective bispecific Wnt mimetics for bone loss and repair. 2021 Nat Commun
Long-term safety evaluation of placental mesenchymal stromal cells for in utero repair of myelomeningocele in a novel ovine model. 2021 J Pediatr Surg
Placental Mesenchymal Stromal Cells: Preclinical Safety Evaluation for Fetal Myelomeningocele Repair. 2021 J Surg Res
Efficacy of clinical-grade human placental mesenchymal stromal cells in fetal ovine myelomeningocele repair. 2021 J Pediatr Surg
A Novel Model of Fetal Spinal Cord Exposure Allowing for Long-Term Postnatal Survival. 2021 Fetal Diagn Ther
Minimizing the risk of occupational Q fever exposure: A protocol for ensuring Coxiella burnetii-negative pregnant ewes are used for medical research. 2021 Lab Anim
Human limbal epithelial stem cell regulation, bioengineering and function. 2021 Prog Retin Eye Res
Limbal stem cell diseases. 2021 Exp Eye Res
Wnt signaling activation: targets and therapeutic opportunities for stem cell therapy and regenerative medicine. 2021 RSC Chem Biol
Bioprinting of dual ECM scaffolds encapsulating limbal stem/progenitor cells in active and quiescent statuses. 2021 Biofabrication
Wnt6 plays a complex role in maintaining human limbal stem/progenitor cells. 2021 Sci Rep
Signaling Pathways That Regulate Normal and Aberrant Red Blood Cell Development. 2021 Genes (Basel)
Deep Learning-Assisted Multiphoton Microscopy to Reduce Light Exposure and Expedite Imaging in Tissues With High and Low Light Sensitivity. 2021 Transl Vis Sci Technol
The Epithelial-Mesenchymal Transcription Factor SNAI1 Represses Transcription of the Tumor Suppressor miRNA let-7 in Cancer. 2021 Cancers (Basel)
Long-Term Hypoxia Maintains a State of Dedifferentiation and Enhanced Stemness in Fetal Cardiovascular Progenitor Cells. 2021 Int J Mol Sci
Superporous agarose scaffolds for encapsulation of adult human islets and human stem-cell-derived beta cells for intravascular bioartificial pancreas applications. 2021 J Biomed Mater Res A
Biophysical matrix cues from the regenerating niche direct muscle stem cell fate in engineered microenvironments. 2021 Biomaterials
Secretomes of human pluripotent stem cell-derived smooth muscle cell progenitors upregulate extracellular matrix metabolism in the lower urinary tract and vagina. 2021 Stem Cell Res Ther
Modeling preeclampsia using human induced pluripotent stem cells. 2021 Sci Rep
peri-Adventitial delivery of smooth muscle cells in porous collagen scaffolds for treatment of experimental abdominal aortic aneurysm. 2021 Biomater Sci
Upregulation of Vitamin C Transporter Functional Expression in 5xFAD Mouse Intestine. 2021 Nutrients
Normal IgH Repertoire Diversity in an Infant with ADA Deficiency After Gene Therapy. 2021 J Clin Immunol
Reliable generation of glial enriched progenitors from human fibroblast-derived iPSCs. 2021 Stem Cell Res
Patient-derived glial enriched progenitors repair functional deficits due to white matter stroke and vascular dementia in rodents. 2021 Sci Transl Med
Autologous Ex Vivo Lentiviral Gene Therapy for Adenosine Deaminase Deficiency. 2021 N Engl J Med
A Human Pleiotropic Multiorgan Condition Caused by Deficient Wnt Secretion. 2021 N Engl J Med
Immune Protection of Stem Cell-Derived Islet Cell Therapy for Treating Diabetes. 2021 Front Endocrinol (Lausanne)
Advances in Pancreatic Islet Transplantation Sites for the Treatment of Diabetes. 2021 Front Endocrinol (Lausanne)
Freshly Thawed Cryobanked Human Neural Stem Cells Engraft within Endogenous Neurogenic Niches and Restore Cognitive Function after Chronic Traumatic Brain Injury. 2021 J Neurotrauma
Non-invasive intradermal imaging of cystine crystals in cystinosis. 2021 PLoS One

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