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Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-beta in iPSC-Derived Alzheimer's Disease Neurons. |
2019 |
Cell Stem Cell |
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Brain organoids as a model system for human neurodevelopment and disease. |
2019 |
Semin Cell Dev Biol |
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Effect of inoculum density on human-induced pluripotent stem cell expansion in 3D bioreactors. |
2019 |
Cell Prolif |
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Online measurement of oxygen enables continuous noninvasive evaluation of human-induced pluripotent stem cell (hiPSC) culture in a perfused 3D hollow-fiber bioreactor. |
2019 |
J Tissue Eng Regen Med |
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Combinatorial targeting of cancer bone metastasis using mRNA engineered stem cells. |
2019 |
EBioMedicine |
|
Genomic Profiling of BDE-47 Effects on Human Placental Cytotrophoblasts. |
2019 |
Toxicol Sci |
|
CRISPR-mediated activation of a promoter or enhancer rescues obesity caused by haploinsufficiency. |
2019 |
Science |
|
Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation. |
2019 |
Nature |
|
Evidence for DNA-mediated nuclear compartmentalization distinct from phase separation. |
2019 |
Elife |
|
Spinal Angulation: A Limitation of the Fetal Lamb Model of Myelomeningocele. |
2019 |
Fetal Diagn Ther |
|
Cardiac fibrosis: potential therapeutic targets. |
2019 |
Transl Res |
|
Harnessing the versatility of PLGA nanoparticles for targeted Cre-mediated recombination. |
2019 |
Nanomedicine |
|
Enhanced Delivery of Oncolytic Adenovirus by Neural Stem Cells for Treatment of Metastatic Ovarian Cancer. |
2019 |
Mol Ther Oncolytics |
|
Generation of pluripotent stem cell-derived mouse kidneys in Sall1-targeted anephric rats. |
2019 |
Nat Commun |
|
LIM homeobox 2 promotes interaction between human iPS-derived hepatic progenitors and iPS-derived hepatic stellate-like cells. |
2019 |
Sci Rep |
|
Highly Efficient and Marker-free Genome Editing of Human Pluripotent Stem Cells by CRISPR-Cas9 RNP and AAV6 Donor-Mediated Homologous Recombination. |
2019 |
Cell Stem Cell |
|
Single-cell genomics identifies cell type-specific molecular changes in autism. |
2019 |
Science |
|
Lentiviral Gene Therapy Combined with Low-Dose Busulfan in Infants with SCID-X1. |
2019 |
N Engl J Med |
|
T cell antigen discovery via trogocytosis. |
2019 |
Nat Methods |
|
Inhibition of invasive pancreatic cancer: restoring cell apoptosis by activating mitochondrial p53. |
2019 |
Am J Cancer Res |
|
LRRK2 modifies alpha-syn pathology and spread in mouse models and human neurons. |
2019 |
Acta Neuropathol |
|
The role of cellular interactions in the induction of hepatocyte polarity and functional maturation in stem cell-derived hepatic cells. |
2019 |
Differentiation |
|
Bortezomib Augments Natural Killer Cell Targeting of Stem-Like Tumor Cells. |
2019 |
Cancers (Basel) |
|
Proteomic analyses reveal misregulation of LIN28 expression and delayed timing of glial differentiation in human iPS cells with MECP2 loss-of-function. |
2019 |
PLoS One |
|
CaMKII inhibition in human primary and pluripotent stem cell-derived chondrocytes modulates effects of TGFbeta and BMP through SMAD signaling. |
2019 |
Osteoarthritis Cartilage |
|
Video-based kinetic analysis of calcification in live osteogenic human embryonic stem cell cultures reveals the developmentally toxic effect of Snus tobacco extract. |
2019 |
Toxicol Appl Pharmacol |
|
Hypoimmunogenic derivatives of induced pluripotent stem cells evade immune rejection in fully immunocompetent allogeneic recipients. |
2019 |
Nat Biotechnol |
|
TFAP2C- and p63-Dependent Networks Sequentially Rearrange Chromatin Landscapes to Drive Human Epidermal Lineage Commitment. |
2019 |
Cell Stem Cell |
|
Metabolic and Organelle Morphology Defects in Mice and Human Patients Define Spinocerebellar Ataxia Type 7 as a Mitochondrial Disease. |
2019 |
Cell Rep |
|
Species-specific maturation profiles of human, chimpanzee and bonobo neural cells. |
2019 |
Elife |
|
Neuroprotective effect of placenta-derived mesenchymal stromal cells: role of exosomes. |
2019 |
FASEB J |
|
T cell antigen discovery via signaling and antigen-presenting bifunctional receptors. |
2019 |
Nat Methods |
|
Development of innate immune cells from human pluripotent stem cells. |
2019 |
Exp Hematol |
|
Off-the-shelf cell therapy with induced pluripotent stem cell-derived natural killer cells. |
2019 |
Semin Immunopathol |
|
Cardiac and skeletal muscle effects in the randomized HOPE-Duchenne trial. |
2019 |
Neurology |
|
Generation of Antigen-Specific T Cells from Human Induced Pluripotent Stem Cells. |
2019 |
Methods Mol Biol |
|
Methotrexate Chemotherapy Induces Persistent Tri-glial Dysregulation that Underlies Chemotherapy-Related Cognitive Impairment. |
2019 |
Cell |
|
Atoh1(+) secretory progenitors possess renewal capacity independent of Lgr5(+) cells during colonic regeneration. |
2019 |
EMBO J |
|
The valproic acid rat model of autism presents with gut bacterial dysbiosis similar to that in human autism. |
2018 |
Mol Autism |
|
Endothelin receptor emerges as a potential target of Hoxa9-mediated leukemogenesis. |
2018 |
Leuk Res |
|
Imaging dynamic and selective low-complexity domain interactions that control gene transcription. |
2018 |
Science |
|
A stable mode of bookmarking by TBP recruits RNA polymerase II to mitotic chromosomes. |
2018 |
Elife |
|
RNA polymerase II clustering through carboxy-terminal domain phase separation. |
2018 |
Nat Struct Mol Biol |
|
Dynamic multifactor hubs interact transiently with sites of active transcription in Drosophila embryos. |
2018 |
Elife |
|
Inflammatory Cytokine TNFalpha Promotes the Long-Term Expansion of Primary Hepatocytes in 3D Culture. |
2018 |
Cell |
|
Accurate, strong, and stable reporting of choroid plexus epithelial cells in transgenic mice using a human transthyretin BAC. |
2018 |
Fluids Barriers CNS |
|
Bcl-2 Overexpression Improves Survival and Efficacy of Neural Stem Cell-Mediated Enzyme Prodrug Therapy. |
2018 |
Stem Cells Int |
|
KIF20A/MKLP2 regulates the division modes of neural progenitor cells during cortical development. |
2018 |
Nat Commun |
|
Programmed cell removal by calreticulin in tissue homeostasis and cancer. |
2018 |
Nat Commun |
|
Autologous Induced Pluripotent Stem Cell-Derived Neurons to Treat Parkinson's Disease. |
2018 |
Stem Cells Dev |
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