Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
Constructing 3D interaction maps from 1D epigenomes. 2016 Nat Commun
Smooth Muscle Precursor Cells Derived from Human Pluripotent Stem Cells for Treatment of Stress Urinary Incontinence. 2016 Stem Cells Dev
Induction of site-specific chromosomal translocations in embryonic stem cells by CRISPR/Cas9. 2016 Sci Rep
The CRISPR Way to Think about Duchenne's. 2016 N Engl J Med
RUNX1 prevents oestrogen-mediated AXIN1 suppression and beta-catenin activation in ER-positive breast cancer. 2016 Nat Commun
Generation and Characterization of Patient-Specific Induced Pluripotent Stem Cell for Disease Modeling. 2016 Methods Mol Biol
YAP Induces Human Naive Pluripotency. 2016 Cell Rep
Comparative neurotoxicity screening in human iPSC-derived neural stem cells, neurons and astrocytes. 2016 Brain Res
Paramagnetic fluorinated nanoemulsions for sensitive cellular fluorine-19 magnetic resonance imaging. 2016 Nat Mater
SOX2 O-GlcNAcylation alters its protein-protein interactions and genomic occupancy to modulate gene expression in pluripotent cells. 2016 Elife
Immunosuppressive Treatment Can Alter Visual Performance in the RCS Rat. 2016 J Ocul Pharmacol Ther
Development of the Mammalian Kidney. 2016 Curr Top Dev Biol
In vivo blunt-end cloning through CRISPR/Cas9-facilitated non-homologous end-joining. 2016 Nucleic Acids Res
Precise Correction of Disease Mutations in Induced Pluripotent Stem Cells Derived From Patients With Limb Girdle Muscular Dystrophy. 2016 Mol Ther
Layered hydrogels accelerate iPSC-derived neuronal maturation and reveal migration defects caused by MeCP2 dysfunction. 2016 Proc Natl Acad Sci U S A
Targeting Transcriptional and Epigenetic Reprogramming in Stromal Cells in Fibrosis and Cancer. 2016 Cold Spring Harb Symp Quant Biol
ERRgamma Is Required for the Metabolic Maturation of Therapeutically Functional Glucose-Responsive beta Cells. 2016 Cell Metab
Modeling autism spectrum disorders with human neurons. 2016 Brain Res
Wnt/beta-catenin and LIF-Stat3 signaling pathways converge on Sp5 to promote mouse embryonic stem cell self-renewal. 2016 J Cell Sci
Spatial Variations in Vitreous Oxygen Consumption. 2016 PLoS One
Genome-wide association study and targeted metabolomics identifies sex-specific association of CPS1 with coronary artery disease. 2016 Nat Commun
A Rational Strategy for the Use of Amniotic Epithelial Stem Cell Therapy for Liver Diseases. 2016 Stem Cells Transl Med
Dysregulated endocardial TGFbeta signaling and mesenchymal transformation result in heart outflow tract septation failure. 2016 Dev Biol
Muscle Tissue Engineering Using Gingival Mesenchymal Stem Cells Encapsulated in Alginate Hydrogels Containing Multiple Growth Factors. 2016 Ann Biomed Eng
Differential regulation of mouse and human nephron progenitors by the Six family of transcriptional regulators. 2016 Development
TLR4 Signaling via NANOG Cooperates With STAT3 to Activate Twist1 and Promote Formation of Tumor-Initiating Stem-Like Cells in Livers of Mice. 2016 Gastroenterology
Correction: Identification of Androgen Receptor Splice Variants in the Pten Deficient Murine Prostate Cancer Model. 2016 PLoS One
Circular RNA profile in gliomas revealed by identification tool UROBORUS. 2016 Nucleic Acids Res
Nuclear transfer nTreg model reveals fate-determining TCR-beta and novel peripheral nTreg precursors. 2016 Proc Natl Acad Sci U S A
Programmable RNA Tracking in Live Cells with CRISPR/Cas9. 2016 Cell
CD13 and ROR2 Permit Isolation of Highly Enriched Cardiac Mesoderm from Differentiating Human Embryonic Stem Cells. 2016 Stem Cell Reports
An Overview of Direct Somatic Reprogramming: The Ins and Outs of iPSCs. 2016 Int J Mol Sci
Loss of miR-203 regulates cell shape and matrix adhesion through ROBO1/Rac/FAK in response to stiffness. 2016 J Cell Biol
Preeclampsia and Inflammatory Preterm Labor Alter the Human Placental Hematopoietic Niche. 2016 Reprod Sci
Cells with surface expression of CD133(high)CD71(low) are enriched for tripotent colony-forming progenitor cells in the adult murine pancreas. 2016 Stem Cell Res
7SK-BAF axis controls pervasive transcription at enhancers. 2016 Nat Struct Mol Biol
Human Mesenchymal Stem Cells Genetically Engineered to Overexpress Brain-derived Neurotrophic Factor Improve Outcomes in Huntington's disease Mouse Models. 2016 Mol Ther
Cockayne Syndrome-derived neurons display reduced synapse density and altered neural network synchrony. 2016 Hum Mol Genet
KCC2 rescues functional deficits in human neurons derived from patients with Rett syndrome. 2016 Proc Natl Acad Sci U S A
Biological impact of xeno-free chemically defined cryopreservation medium on amniotic epithelial cells. 2016 Stem Cell Res Ther
Magnetic Resonance Imaging of Iron Oxide-Labeled Human Embryonic Stem Cell-Derived Cardiac Progenitors. 2016 Stem Cells Transl Med
Personalized medicine for effective Alzheimer disease treatment. 2015 JAMA Neurol
CBP/catenin antagonist safely eliminates drug-resistant leukemia-initiating cells. 2015 Oncogene
The splicing regulator PTBP1 controls the activity of the transcription factor Pbx1 during neuronal differentiation. 2015 Elife
Mitochondrial alterations by PARKIN in dopaminergic neurons using PARK2 patient-specific and PARK2 knockout isogenic iPSC lines. 2015 Stem Cell Reports
A platform for rapid generation of single and multiplexed reporters in human iPSC lines. 2015 Sci Rep
Tau-er of Power. 2015 Cerebrum
hESC Differentiation toward an Autonomic Neuronal Cell Fate Depends on Distinct Cues from the Co-Patterning Vasculature. 2015 Stem Cell Reports
Pluripotent stem cell energy metabolism: an update. 2015 EMBO J
Concise Review: Manufacturing of Pancreatic Endoderm Cells for Clinical Trials in Type 1 Diabetes. 2015 Stem Cells Transl Med

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