Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
CD13 and ROR2 Permit Isolation of Highly Enriched Cardiac Mesoderm from Differentiating Human Embryonic Stem Cells. 2016 Stem Cell Reports
An Overview of Direct Somatic Reprogramming: The Ins and Outs of iPSCs. 2016 Int J Mol Sci
Human Mesenchymal Stem Cells Genetically Engineered to Overexpress Brain-derived Neurotrophic Factor Improve Outcomes in Huntington's disease Mouse Models. 2016 Mol Ther
Cockayne Syndrome-derived neurons display reduced synapse density and altered neural network synchrony. 2016 Hum Mol Genet
KCC2 rescues functional deficits in human neurons derived from patients with Rett syndrome. 2016 Proc Natl Acad Sci U S A
Biological impact of xeno-free chemically defined cryopreservation medium on amniotic epithelial cells. 2016 Stem Cell Res Ther
Magnetic Resonance Imaging of Iron Oxide-Labeled Human Embryonic Stem Cell-Derived Cardiac Progenitors. 2016 Stem Cells Transl Med
Generation of Genetically Modified Organotypic Skin Cultures Using Devitalized Human Dermis. 2015 J Vis Exp
DDX6 Orchestrates Mammalian Progenitor Function through the mRNA Degradation and Translation Pathways. 2015 Mol Cell
Unifying the DNA end-processing roles of the artemis nuclease: Ku-dependent artemis resection at blunt DNA ends. 2015 J Biol Chem
Determinants in HIV-2 Env and tetherin required for functional interaction. 2015 Retrovirology
Feather on the Cap of Medicine. 2015 J Invest Dermatol
The Genetic Architecture of Hearing Impairment in Mice: Evidence for Frequency-Specific Genetic Determinants. 2015 G3 (Bethesda)
The Genetic Landscape of Hematopoietic Stem Cell Frequency in Mice. 2015 Stem Cell Reports
Small-conductance Ca2+ -activated K+ channels and cardiac arrhythmias. 2015 Heart Rhythm
Translational aspects of cardiac cell therapy. 2015 J Cell Mol Med
Sox9 Activation Highlights a Cellular Pathway of Renal Repair in the Acutely Injured Mammalian Kidney. 2015 Cell Rep
Sensory hair cell development and regeneration: similarities and differences. 2015 Development
Lgr5+ cells regenerate hair cells via proliferation and direct transdifferentiation in damaged neonatal mouse utricle. 2015 Nat Commun
CD93 Marks a Non-Quiescent Human Leukemia Stem Cell Population and Is Required for Development of MLL-Rearranged Acute Myeloid Leukemia. 2015 Cell Stem Cell
Bilayered vascular graft derived from human induced pluripotent stem cells with biomimetic structure and function. 2015 Regen Med
Progressive Chromatin Condensation and H3K9 Methylation Regulate the Differentiation of Embryonic and Hematopoietic Stem Cells. 2015 Stem Cell Reports
HIV-specific Immunity Derived From Chimeric Antigen Receptor-engineered Stem Cells. 2015 Mol Ther
Long-Term Controlled Protein Release from Poly(Ethylene Glycol) Hydrogels by Modulating Mesh Size and Degradation. 2015 Macromol Biosci
Effects of the poly(ethylene glycol) hydrogel crosslinking mechanism on protein release. 2015 Biomater Sci
Dynamic and social behaviors of human pluripotent stem cells. 2015 Sci Rep
Cellular postconditioning: allogeneic cardiosphere-derived cells reduce infarct size and attenuate microvascular obstruction when administered after reperfusion in pigs with acute myocardial infarction. 2015 Circ Heart Fail
Therapeutic efficacy of cardiosphere-derived cells in a transgenic mouse model of non-ischaemic dilated cardiomyopathy. 2015 Eur Heart J
ETV2 expression increases the efficiency of primitive endothelial cell derivation from human embryonic stem cells. 2015 Cell Regen (Lond)
Bioactivity and Safety of IL13Ralpha2-Redirected Chimeric Antigen Receptor CD8+ T Cells in Patients with Recurrent Glioblastoma. 2015 Clin Cancer Res
Smart CARs engineered for cancer immunotherapy. 2015 Curr Opin Oncol
Identification of novel long noncoding RNAs underlying vertebrate cardiovascular development. 2015 Circulation
Differential regenerative capacity of neonatal mouse hearts after cryoinjury. 2015 Dev Biol
Mesenchymal adenomatous polyposis coli plays critical and diverse roles in regulating lung development. 2015 BMC Biol
Generation of tissue-engineered small intestine using embryonic stem cell-derived human intestinal organoids. 2015 Biol Open
Human and mouse tissue-engineered small intestine both demonstrate digestive and absorptive function. 2015 Am J Physiol Gastrointest Liver Physiol
A novel, long-lived, and highly engraftable immunodeficient mouse model of mucopolysaccharidosis type I. 2015 Mol Ther Methods Clin Dev
Stereoselective synthesis of mexiletine and structural analogs with chiral tert-butanesulfinamide 2015 Tetrahedron Letters
Erk Negative Feedback Control Enables Pre-B Cell Transformation and Represents a Therapeutic Target in Acute Lymphoblastic Leukemia. 2015 Cancer Cell
Identification of FOXM1 as a therapeutic target in B-cell lineage acute lymphoblastic leukaemia. 2015 Nat Commun
Self-enforcing feedback activation between BCL6 and pre-B cell receptor signaling defines a distinct subtype of acute lymphoblastic leukemia. 2015 Cancer Cell
Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia. 2015 Nature
Rationale for targeting the pre-B-cell receptor signaling pathway in acute lymphoblastic leukemia. 2015 Blood
Ph+ ALL: drawing strength from a benign past. 2015 Blood
Mechanisms of clonal evolution in childhood acute lymphoblastic leukemia. 2015 Nat Immunol
HiTSelect: a comprehensive tool for high-complexity-pooled screen analysis. 2015 Nucleic Acids Res
Stem cell based therapies for age-related macular degeneration: The promises and the challenges. 2015 Prog Retin Eye Res
A novel profibrotic mechanism mediated by TGFbeta-stimulated collagen prolyl hydroxylase expression in fibrotic lung mesenchymal cells. 2015 J Pathol
Functional and mechanistic studies of XPC DNA-repair complex as transcriptional coactivator in embryonic stem cells. 2015 Proc Natl Acad Sci U S A
Dynamics of CRISPR-Cas9 genome interrogation in living cells. 2015 Science

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