Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
Deriving Dorsal Spinal Sensory Interneurons from Human Pluripotent Stem Cells. 2018 Stem Cell Reports
Macrochimerism and clinical transplant tolerance. 2018 Hum Immunol
Blocking Zika virus vertical transmission. 2018 Sci Rep
Essential Role of Nr2f Nuclear Receptors in Patterning the Vertebrate Upper Jaw. 2018 Dev Cell
Bad wrap: Myelin and myelin plasticity in health and disease. 2018 Dev Neurobiol
ERBB3 and NGFR mark a distinct skeletal muscle progenitor cell in human development and hPSCs. 2018 Nat Cell Biol
An All-Recombinant Protein-Based Culture System Specifically Identifies Hematopoietic Stem Cell Maintenance Factors. 2017 Stem Cell Reports
Interspecies organogenesis generates autologous functional islets. 2017 Nature
Mammalian Transcription Factor Networks: Recent Advances in Interrogating Biological Complexity. 2017 Cell Syst
Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis. 2017 Proc Natl Acad Sci U S A
An Automated Platform for Assessment of Congenital and Drug-Induced Arrhythmia with hiPSC-Derived Cardiomyocytes. 2017 Front Physiol
Three-Dimensional Bioprinting and Its Potential in the Field of Articular Cartilage Regeneration. 2017 Cartilage
BMPs direct sensory interneuron identity in the developing spinal cord using signal-specific not morphogenic activities. 2017 Elife
Human fetal liver cultures support multiple cell lineages that can engraft immunodeficient mice. 2017 Open Biol
Identification and characterization of a rich population of CD34(+) mesenchymal stem/stromal cells in human parotid, sublingual and submandibular glands. 2017 Sci Rep
Cellular Phenotypes in Human iPSC-Derived Neurons from a Genetic Model of Autism Spectrum Disorder. 2017 Cell Rep
A Rationally Designed, General Strategy for Membrane Orientation of Photoinduced Electron Transfer-Based Voltage-Sensitive Dyes. 2017 ACS Chem Biol
Engineered hydrogels increase the post-transplantation survival of encapsulated hESC-derived midbrain dopaminergic neurons. 2017 Biomaterials
Repurposing of the anti-malaria drug chloroquine for Zika Virus treatment and prophylaxis. 2017 Sci Rep
Tunneling Nanotubes and Gap Junctions-Their Role in Long-Range Intercellular Communication during Development, Health, and Disease Conditions. 2017 Front Mol Neurosci
Transplantation of wild-type mouse hematopoietic stem and progenitor cells ameliorates deficits in a mouse model of Friedreich's ataxia. 2017 Sci Transl Med
Frequency of mononuclear diploid cardiomyocytes underlies natural variation in heart regeneration. 2017 Nat Genet
A novel protein-engineered hepatocyte growth factor analog released via a shear-thinning injectable hydrogel enhances post-infarction ventricular function. 2017 Biotechnol Bioeng
Maintenance of neural progenitor cell stemness in 3D hydrogels requires matrix remodelling. 2017 Nat Mater
Use of the DICE (Dual Integrase Cassette Exchange) System. 2017 Methods Mol Biol
DNA-Mediated Gene Therapy in a Mouse Model of Limb Girdle Muscular Dystrophy 2B. 2017 Mol Ther Methods Clin Dev
Self-Organized Cerebral Organoids with Human-Specific Features Predict Effective Drugs to Combat Zika Virus Infection. 2017 Cell Rep
Requirement for Jagged1-Notch2 signaling in patterning the bones of the mouse and human middle ear. 2017 Sci Rep
A minimally sufficient model for rib proximal-distal patterning based on genetic analysis and agent-based simulations. 2017 Elife
Wnt/beta-catenin activation and macrophage induction during liver cancer development following steatosis. 2017 Oncogene
Neural Precursor-Derived Pleiotrophin Mediates Subventricular Zone Invasion by Glioma. 2017 Cell
Targeting neuronal activity-regulated neuroligin-3 dependency in high-grade glioma. 2017 Nature
Wrapped to Adapt: Experience-Dependent Myelination. 2017 Neuron
Placental mesenchymal stromal cells seeded on clinical grade extracellular matrix improve ambulation in ovine myelomeningocele. 2017 J Pediatr Surg
Fetal surgical repair with placenta-derived mesenchymal stromal cell engineered patch in a rodent model of myelomeningocele. 2017 J Pediatr Surg
Human Neural Stem Cell Transplantation Rescues Functional Deficits in R6/2 and Q140 Huntington's Disease Mice. 2017 Stem Cell Reports
Bcl11b and combinatorial resolution of cell fate in the T-cell gene regulatory network. 2017 Proc Natl Acad Sci U S A
The ErbB3 receptor tyrosine kinase negatively regulates Paneth cells by PI3K-dependent suppression of Atoh1. 2017 Cell Death Differ
Menthol Enhances Nicotine Reward-Related Behavior by Potentiating Nicotine-Induced Changes in nAChR Function, nAChR Upregulation, and DA Neuron Excitability. 2017 Neuropsychopharmacology
Reliable Identification of Living Dopaminergic Neurons in Midbrain Cultures Using RNA Sequencing and TH-promoter-driven eGFP Expression. 2017 J Vis Exp
Smek promotes corticogenesis through regulating Mbd3's stability and Mbd3/NuRD complex recruitment to genes associated with neurogenesis. 2017 PLoS Biol
A CD47-associated super-enhancer links pro-inflammatory signalling to CD47 upregulation in breast cancer. 2017 Nat Commun
A Novel Hybrid Compound LLP2A-Ale Both Prevented and Rescued the Osteoporotic Phenotype in a Mouse Model of Glucocorticoid-Induced Osteoporosis. 2017 Calcif Tissue Int
Neural Crest Cell Implantation Restores Enteric Nervous System Function and Alters the Gastrointestinal Transcriptome in Human Tissue-Engineered Small Intestine. 2017 Stem Cell Reports
Tissue Engineering Functional Gastrointestinal Regions: The Importance of Stem and Progenitor Cells. 2017 Cold Spring Harb Perspect Med
Created of Warm Blood and Nerves: Restoring an Enteric Nervous System in Organoids. 2017 Cell Stem Cell
Report of the International Stem Cell Banking Initiative Workshop Activity: Current Hurdles and Progress in Seed-Stock Banking of Human Pluripotent Stem Cells. 2017 Stem Cells Transl Med
Systematic discovery of mutation-specific synthetic lethals by mining pan-cancer human primary tumor data. 2017 Nat Commun
Multiplexed genetic engineering of human hematopoietic stem and progenitor cells using CRISPR/Cas9 and AAV6. 2017 Elife
Generation and use of a humanized bone-marrow-ossicle niche for hematopoietic xenotransplantation into mice. 2017 Nat Protoc

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