In Utero Treatment of Myelomeningocele with Placental Mesenchymal Stromal Cells - Selection of an Optimal Cell Line in Preparation for Clinical Trials. |
2019 |
J Pediatr Surg |
Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy. |
2019 |
Nature |
Establishing Cerebral Organoids as Models of Human-Specific Brain Evolution. |
2019 |
Cell |
Modeling Spatial Correlation of Transcripts with Application to Developing Pancreas. |
2019 |
Sci Rep |
Precise in vivo genome editing via single homology arm donor mediated intron-targeting gene integration for genetic disease correction. |
2019 |
Cell Res |
Circulating tumor cells exhibit metastatic tropism and reveal brain metastasis drivers. |
2019 |
Cancer Discov |
An Improved Two-Step Protocol for Trophoblast Differentiation of Human Pluripotent Stem Cells. |
2019 |
Curr Protoc Stem Cell Biol |
Wnt Signaling Is Required for the Maintenance of Human Limbal Stem/Progenitor Cells In Vitro. |
2019 |
Invest Ophthalmol Vis Sci |
Diagnostic criteria for limbal stem cell deficiency before surgical intervention-A systematic literature review and analysis. |
2019 |
Surv Ophthalmol |
Mesenchymal Stem Cells Reduce Corneal Fibrosis and Inflammation via Extracellular Vesicle-Mediated Delivery of miRNA. |
2019 |
Stem Cells Transl Med |
Notch Inhibition Prevents Differentiation of Human Limbal Stem/Progenitor Cells in vitro. |
2019 |
Sci Rep |
Human induced pluripotent stem cell line with genetically encoded fluorescent voltage indicator generated via CRISPR for action potential assessment post-cardiogenesis. |
2019 |
Stem Cells |
Classification of Limbal Stem Cell Deficiency Using Clinical and Confocal Grading. |
2019 |
Cornea |
The application of human amniotic membrane in the surgical management of limbal stem cell deficiency. |
2019 |
Ocul Surf |
Comparison of endothelial keratoplasty techniques in patients with prior glaucoma surgery - a case-matched study. |
2019 |
Am J Ophthalmol |
Chronic myelogenous leukemia stem cells require cell-autonomous pleiotrophin signaling. |
2019 |
J Clin Invest |
PTPsigma inhibitors promote hematopoietic stem cell regeneration. |
2019 |
Nat Commun |
Phenotypic Variation Between Stromal Cells Differentially Impacts Engineered Cardiac Tissue Function. |
2019 |
Tissue Eng Part A |
Determining the pharmacokinetics of nicotinic drugs in the endoplasmic reticulum using biosensors. |
2019 |
J Gen Physiol |
Development of a Chimeric Model to Study and Manipulate Human Microglia In Vivo. |
2019 |
Neuron |
Fiber-based platform for synchronous imaging of endogenous and exogenous fluorescence of biological tissue. |
2019 |
Opt Lett |
Complex Oscillatory Waves Emerging from Cortical Organoids Model Early Human Brain Network Development. |
2019 |
Cell Stem Cell |
Transposable Elements, Inflammation, and Neurological Disease. |
2019 |
Front Neurol |
Brain Organoids as Tools for Modeling Human Neurodevelopmental Disorders. |
2019 |
Physiology (Bethesda) |
Anti-human CD117 antibody-mediated bone marrow niche clearance in nonhuman primates and humanized NSG mice. |
2019 |
Blood |
Anti-CD117 antibody depletes normal and myelodysplastic syndrome human hematopoietic stem cells in xenografted mice. |
2019 |
Blood |
Selective hematopoietic stem cell ablation using CD117-antibody-drug-conjugates enables safe and effective transplantation with immunity preservation. |
2019 |
Nat Commun |
Fluorous-Soluble Metal Chelate for Sensitive Fluorine-19 Magnetic Resonance Imaging Nanoemulsion Probes. |
2019 |
ACS Nano |
Paramagnetic Fluorinated Nanoemulsions for in vivo F-19 MRI. |
2019 |
Mol Imaging Biol |
Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-beta in iPSC-Derived Alzheimer's Disease Neurons. |
2019 |
Cell Stem Cell |
Brain organoids as a model system for human neurodevelopment and disease. |
2019 |
Semin Cell Dev Biol |
Effect of inoculum density on human-induced pluripotent stem cell expansion in 3D bioreactors. |
2019 |
Cell Prolif |
Online measurement of oxygen enables continuous noninvasive evaluation of human-induced pluripotent stem cell (hiPSC) culture in a perfused 3D hollow-fiber bioreactor. |
2019 |
J Tissue Eng Regen Med |
Combinatorial targeting of cancer bone metastasis using mRNA engineered stem cells. |
2019 |
EBioMedicine |
Genomic Profiling of BDE-47 Effects on Human Placental Cytotrophoblasts. |
2019 |
Toxicol Sci |
CRISPR-mediated activation of a promoter or enhancer rescues obesity caused by haploinsufficiency. |
2019 |
Science |
Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation. |
2019 |
Nature |
Evidence for DNA-mediated nuclear compartmentalization distinct from phase separation. |
2019 |
Elife |
Spinal Angulation: A Limitation of the Fetal Lamb Model of Myelomeningocele. |
2019 |
Fetal Diagn Ther |
Cardiac fibrosis: potential therapeutic targets. |
2019 |
Transl Res |
Harnessing the versatility of PLGA nanoparticles for targeted Cre-mediated recombination. |
2019 |
Nanomedicine |
Enhanced Delivery of Oncolytic Adenovirus by Neural Stem Cells for Treatment of Metastatic Ovarian Cancer. |
2019 |
Mol Ther Oncolytics |
Generation of pluripotent stem cell-derived mouse kidneys in Sall1-targeted anephric rats. |
2019 |
Nat Commun |
LIM homeobox 2 promotes interaction between human iPS-derived hepatic progenitors and iPS-derived hepatic stellate-like cells. |
2019 |
Sci Rep |
Highly Efficient and Marker-free Genome Editing of Human Pluripotent Stem Cells by CRISPR-Cas9 RNP and AAV6 Donor-Mediated Homologous Recombination. |
2019 |
Cell Stem Cell |
Single-cell genomics identifies cell type-specific molecular changes in autism. |
2019 |
Science |
Lentiviral Gene Therapy Combined with Low-Dose Busulfan in Infants with SCID-X1. |
2019 |
N Engl J Med |
T cell antigen discovery via trogocytosis. |
2019 |
Nat Methods |
Inhibition of invasive pancreatic cancer: restoring cell apoptosis by activating mitochondrial p53. |
2019 |
Am J Cancer Res |
LRRK2 modifies alpha-syn pathology and spread in mouse models and human neurons. |
2019 |
Acta Neuropathol |