Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
Human neural stem cell-derived extracellular vesicles mitigate hallmarks of Alzheimer's disease. 2021 Alzheimers Res Ther
ApoE-Isoform-Dependent SARS-CoV-2 Neurotropism and Cellular Response. 2021 Cell Stem Cell
Inflammation-driven deaminase deregulation fuels human pre-leukemia stem cell evolution. 2021 Cell Rep
Selective antisense oligonucleotide inhibition of human IRF4 prevents malignant myeloma regeneration via cell cycle disruption. 2021 Cell Stem Cell
Foxp1 Regulates Neural Stem Cell Self-Renewal and Bias Toward Deep Layer Cortical Fates. 2020 Cell Rep
A Human Skeletal Muscle Atlas Identifies the Trajectories of Stem and Progenitor Cells across Development and from Human Pluripotent Stem Cells. 2020 Cell Stem Cell
Pluripotent Stem Cell-Based Organoid Technologies for Developing Next-Generation Vision Restoration Therapies of Blindness. 2020 J Ocul Pharmacol Ther
Chemical Elements in Electronic Cigarette Solvents and Aerosols Inhibit Mitochondrial Reductases and Induce Oxidative Stress. 2020 Nicotine Tob Res
Extracellular Vesicles for the Treatment of Radiation-Induced Normal Tissue Toxicity in the Lung. 2020 Front Oncol
Immune and Inflammatory Determinants Underlying Alzheimer's Disease Pathology. 2020 J Neuroimmune Pharmacol
Cell-Based Therapy for Canavan Disease Using Human iPSC-Derived NPCs and OPCs. 2020 Adv Sci (Weinh)
When glia meet induced pluripotent stem cells (iPSCs). 2020 Mol Cell Neurosci
Grading TESI: Crypt and villus formation in tissue-engineered small intestine alters with stem/progenitor cell source. 2020 Am J Physiol Gastrointest Liver Physiol
Mixed chimerism and acceptance of kidney transplants after immunosuppressive drug withdrawal. 2020 Sci Transl Med
Neural Stem Cells Improve the Delivery of Oncolytic Chimeric Orthopoxvirus in a Metastatic Ovarian Cancer Model. 2020 Mol Ther Oncolytics
Specific targeting of ovarian tumor-associated macrophages by large, anionic nanoparticles. 2020 Proc Natl Acad Sci U S A
SUMOylation of E2F1 Regulates Expression of EZH2. 2020 Cancer Res
Fat grafting rescues radiation-induced joint contracture. 2020 Stem Cells
Northstar enables automatic classification of known and novel cell types from tumor samples. 2020 Sci Rep
mTOR signaling regulates the morphology and migration of outer radial glia in developing human cortex. 2020 Elife
Engineering CAR T Cells to Target the HIV Reservoir. 2020 Front Cell Infect Microbiol
Articular cartilage regeneration by activated skeletal stem cells. 2020 Nat Med
Mutations in Spliceosomal Genes PPIL1 and PRP17 Cause Neurodegenerative Pontocerebellar Hypoplasia with Microcephaly. 2020 Neuron
Surviving Lambs with Myelomeningocele Repaired in utero with Placental Mesenchymal Stromal Cells for 6 Months: A Pilot Study. 2020 Fetal Diagn Ther
Interleukin 7 receptor is required for myeloid cell homeostasis and reconstitution by hematopoietic stem cells. 2020 Exp Hematol
A new anabolic compound, LLP2A-Ale, reserves periodontal bone loss in mice through augmentation of bone formation. 2020 BMC Pharmacol Toxicol
Virus-specific T-cell therapies for patients with primary immune deficiency. 2020 Blood
Tumor necrosis factor overcomes immune evasion in p53-mutant medulloblastoma. 2020 Nat Neurosci
NODAL inhibition promotes differentiation of pacemaker-like cardiomyocytes from human induced pluripotent stem cells. 2020 Stem Cell Res
Systemic Anti-PD-1 Immunotherapy Results in PD-1 Blockade on T Cells in the Cerebrospinal Fluid. 2020 JAMA Oncol
Heavy metals contaminating the environment of a progressive supranuclear palsy cluster induce tau accumulation and cell death in cultured neurons. 2020 Sci Rep
Novel C1q receptor-mediated signaling controls neural stem cell behavior and neurorepair. 2020 Elife
Adeno-Associated Virus and Hematopoietic Stem Cells: The Potential of Adeno-Associated Virus Hematopoietic Stem Cells in Genetic Medicines. 2020 Hum Gene Ther
Immune-evasive human islet-like organoids ameliorate diabetes. 2020 Nature
Retina Organoid Transplants Develop Photoreceptors and Improve Visual Function in RCS Rats With RPE Dysfunction. 2020 Invest Ophthalmol Vis Sci
Functionally heterogeneous human satellite cells identified by single cell RNA sequencing. 2020 Elife
Lentiviral gene therapy for X-linked chronic granulomatous disease. 2020 Nat Med
Busulfan Pharmacokinetics in Adenosine Deaminase-Deficient Severe Combined Immunodeficiency Gene Therapy. 2020 Biol Blood Marrow Transplant
Loss of NARS1 impairs progenitor proliferation in cortical brain organoids and leads to microcephaly. 2020 Nat Commun
Stem Cells and Lung Regeneration. 2020 Am J Physiol Cell Physiol
Broad-spectrum antibiotics alter the microbiome, increase intestinal fxr, and decrease hepatic steatosis in zebrafish short bowel syndrome. 2020 Am J Physiol Gastrointest Liver Physiol
Post-Transcriptional Regulation of Homeostatic, Stressed, and Malignant Stem Cells. 2020 Cell Stem Cell
Multiexon deletion alleles of ATF6 linked to achromatopsia. 2020 JCI Insight
Splice Modulation Synergizes Cell Cycle Inhibition. 2020 ACS Chem Biol
Three-dimensional bioprinted glioblastoma microenvironments model cellular dependencies and immune interactions. 2020 Cell Res
Epithelial/mesenchymal heterogeneity of high-grade serous ovarian carcinoma samples correlates with miRNA let-7 levels and predicts tumor growth and metastasis. 2020 Mol Oncol
PAWI-2 overcomes tumor stemness and drug resistance via cell cycle arrest in integrin beta3-KRAS-dependent pancreatic cancer stem cells. 2020 Sci Rep
Clonal isolation of endothelial colony-forming cells from early gestation chorionic villi of human placenta for fetal tissue regeneration. 2020 World J Stem Cells
A Decade of Experience with the Ovine Model of Myelomeningocele: Risk Factors for Fetal Loss. 2020 Fetal Diagn Ther
Global Consensus on the Management of Limbal Stem Cell Deficiency. 2020 Cornea


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