Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
Dynamics of CRISPR-Cas9 genome interrogation in living cells. 2015 Science
Chemical perturbation of an intrinsically disordered region of TFIID distinguishes two modes of transcription initiation. 2015 Elife
A specific E3 ligase/deubiquitinase pair modulates TBP protein levels during muscle differentiation. 2015 Elife
Mesenchymal adenomatous polyposis coli plays critical and diverse roles in regulating lung development. 2015 BMC Biol
A novel profibrotic mechanism mediated by TGFbeta-stimulated collagen prolyl hydroxylase expression in fibrotic lung mesenchymal cells. 2015 J Pathol
Functional and mechanistic studies of XPC DNA-repair complex as transcriptional coactivator in embryonic stem cells. 2015 Proc Natl Acad Sci U S A
Differential regenerative capacity of neonatal mouse hearts after cryoinjury. 2015 Dev Biol
Brief Report: Oxidative Stress Mediates Cardiomyocyte Apoptosis in a Human Model of Danon Disease and Heart Failure. 2015 Stem Cells
Direct reprogramming of fibroblasts into cardiomyocytes for cardiac regenerative medicine. 2015 Circ J
Replication Stress and Telomere Dysfunction Are Present in Cultured Human Embryonic Stem Cells. 2015 Cytogenet Genome Res
Epigenetic Priming of Enhancers Predicts Developmental Competence of hESC-Derived Endodermal Lineage Intermediates. 2015 Cell Stem Cell
A functional genomics screen identifies an Importin-alpha homolog as a regulator of stem cell function and tissue patterning during planarian regeneration. 2015 BMC Genomics
Embolization of the first diagonal branch of the left anterior descending coronary artery as a porcine model of chronic trans-mural myocardial infarction. 2015 J Transl Med
Small intestinal submucosa-derived extracellular matrix bioscaffold significantly enhances angiogenic factor secretion from human mesenchymal stromal cells. 2015 Stem Cell Res Ther
Cardiac extracellular matrix proteomics: Challenges, techniques, and clinical implications. 2015 Proteomics Clin Appl
Efficient Generation of Induced Pluripotent Stem and Neural Progenitor Cells From Acutely Harvested Dura Mater Obtained During Ventriculoperitoneal Shunt Surgery. 2015 World Neurosurg
Placental mesenchymal stromal cells rescue ambulation in ovine myelomeningocele. 2015 Stem Cells Transl Med
Development of a locomotor rating scale for testing motor function in sheep. 2015 J Pediatr Surg
Dynamic regulation of mRNA decay during neural development. 2015 Neural Dev
Multiple intravenous injections of allogeneic equine mesenchymal stem cells do not induce a systemic inflammatory response but do alter lymphocyte subsets in healthy horses. 2015 Stem Cell Res Ther
Age Does Matter: A Pilot Comparison of Placenta-Derived Stromal Cells for in utero Repair of Myelomeningocele Using a Lamb Model. 2015 Fetal Diagn Ther
Altered neuronal network and rescue in a human MECP2 duplication model. 2015 Mol Psychiatry
Forward engineering neuronal diversity using direct reprogramming. 2015 EMBO J
Selective conversion of fibroblasts into peripheral sensory neurons. 2015 Nat Neurosci
Nemo-like kinase is a novel regulator of spinal and bulbar muscular atrophy. 2015 Elife
Effects of ATP and NGF on Proliferation and Migration of Neural Precursor Cells. 2015 Neurochem Res
Roles of kinins in the nervous system. 2015 Cell Transplant
Paraoxon and Pyridostigmine Interfere with Neural Stem Cell Differentiation. 2015 Neurochem Res
Developing stem cell therapies for juvenile and adult-onset Huntington's disease. 2015 Regen Med
Stereoselective synthesis of mexiletine and structural analogs with chiral tert-butanesulfinamide 2015 Tetrahedron Letters
Large-scale production of lentiviral vector in a closed system hollow fiber bioreactor. 2015 Mol Ther Methods Clin Dev
1,5-Disubstituted benzimidazoles that direct cardiomyocyte differentiation from mouse embryonic stem cells. 2015 Bioorg Med Chem
The Human Model: Changing Focus on Autism Research. 2015 Biol Psychiatry
Altered iPSC-derived neurons' sodium channel properties in subjects with Monge's disease. 2015 Neuroscience
Systematic optimization of human pluripotent stem cells media using Design of Experiments. 2015 Sci Rep
The Use of Induced Pluripotent Stem Cell Technology to Advance Autism Research and Treatment. 2015 Neurotherapeutics
beta2-microglobulin is a systemic pro-aging factor that impairs cognitive function and neurogenesis. 2015 Nat Med
Mesenchymal Stem Cells Respond to Hypoxia by Increasing Diacylglycerols. 2015 J Cell Biochem
Hypoxic preconditioning of mesenchymal stromal cells induces metabolic changes, enhances survival, and promotes cell retention in vivo. 2015 Stem Cells
Development of 2-Deoxy-2-[(18)F]fluororibose for Positron Emission Tomography Imaging Liver Function in Vivo. 2015 J Med Chem
Importance of defining experimental conditions in a mouse excisional wound model. 2015 Wound Repair Regen
Human Engineered Heart Muscles Engraft and Survive Long-Term in a Rodent Myocardial Infarction Model. 2015 Circ Res
Using phage integrases in a site-specific dual integrase cassette exchange strategy. 2015 Methods Mol Biol
Genetic engineering of hematopoietic stem cells to generate invariant natural killer T cells. 2015 Proc Natl Acad Sci U S A
An estrogen-responsive module in the ventromedial hypothalamus selectively drives sex-specific activity in females. 2015 Cell Rep
Simultaneous deletion of NOD1 and NOD2 inhibits in vitro alloresponses but does not prevent allograft rejection. 2015 Immunobiology
Novel monoclonal antibodies to study tissue regeneration in planarians. 2015 BMC Dev Biol
A quantitative assessment of the content of hematopoietic stem cells in mouse and human endosteal-bone marrow: a simple and rapid method for the isolation of mouse central bone marrow. 2015 BMC Hematol
TGF-beta2 secretion from RPE decreases with polarization and becomes apically oriented. 2015 Cytokine
The long noncoding RNA pnky regulates neuronal differentiation of embryonic and postnatal neural stem cells. 2015 Cell Stem Cell


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