Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
Inhibition of invasive pancreatic cancer: restoring cell apoptosis by activating mitochondrial p53. 2019 Am J Cancer Res
LRRK2 modifies alpha-syn pathology and spread in mouse models and human neurons. 2019 Acta Neuropathol
The role of cellular interactions in the induction of hepatocyte polarity and functional maturation in stem cell-derived hepatic cells. 2019 Differentiation
Bortezomib Augments Natural Killer Cell Targeting of Stem-Like Tumor Cells. 2019 Cancers (Basel)
Proteomic analyses reveal misregulation of LIN28 expression and delayed timing of glial differentiation in human iPS cells with MECP2 loss-of-function. 2019 PLoS One
CaMKII inhibition in human primary and pluripotent stem cell-derived chondrocytes modulates effects of TGFbeta and BMP through SMAD signaling. 2019 Osteoarthritis Cartilage
Video-based kinetic analysis of calcification in live osteogenic human embryonic stem cell cultures reveals the developmentally toxic effect of Snus tobacco extract. 2019 Toxicol Appl Pharmacol
Hypoimmunogenic derivatives of induced pluripotent stem cells evade immune rejection in fully immunocompetent allogeneic recipients. 2019 Nat Biotechnol
TFAP2C- and p63-Dependent Networks Sequentially Rearrange Chromatin Landscapes to Drive Human Epidermal Lineage Commitment. 2019 Cell Stem Cell
Neuroprotective effect of placenta-derived mesenchymal stromal cells: role of exosomes. 2019 FASEB J
Metabolic and Organelle Morphology Defects in Mice and Human Patients Define Spinocerebellar Ataxia Type 7 as a Mitochondrial Disease. 2019 Cell Rep
Species-specific maturation profiles of human, chimpanzee and bonobo neural cells. 2019 Elife
T cell antigen discovery via signaling and antigen-presenting bifunctional receptors. 2019 Nat Methods
T cell antigen discovery via trogocytosis. 2019 Nat Methods
Off-the-shelf cell therapy with induced pluripotent stem cell-derived natural killer cells. 2019 Semin Immunopathol
Development of innate immune cells from human pluripotent stem cells. 2019 Exp Hematol
Cardiac and skeletal muscle effects in the randomized HOPE-Duchenne trial. 2019 Neurology
Generation of Antigen-Specific T Cells from Human Induced Pluripotent Stem Cells. 2019 Methods Mol Biol
Methotrexate Chemotherapy Induces Persistent Tri-glial Dysregulation that Underlies Chemotherapy-Related Cognitive Impairment. 2019 Cell
Atoh1(+) secretory progenitors possess renewal capacity independent of Lgr5(+) cells during colonic regeneration. 2019 EMBO J
A pathway for Parkinson's Disease LRRK2 kinase to block primary cilia and Sonic hedgehog signaling in the brain. 2018 Elife
Distinct Bone Marrow Sources of Pleiotrophin Control Hematopoietic Stem Cell Maintenance and Regeneration. 2018 Cell Stem Cell
Wild-type Kras expands and exhausts hematopoietic stem cells. 2018 JCI Insight
PNPase knockout results in mtDNA loss and an altered metabolic gene expression program. 2018 PLoS One
Stem Cell-Based Immunomodulation After Stroke: Effects on Brain Repair Processes. 2018 Stroke
Engineered stem cell mimics to enhance stroke recovery. 2018 Biomaterials
Mapping molecular landmarks of human skeletal ontogeny and pluripotent stem cell-derived articular chondrocytes. 2018 Nat Commun
Drug-induced modulation of gp130 signalling prevents articular cartilage degeneration and promotes repair. 2018 Ann Rheum Dis
Nanoparticle Delivery of TWIST Small Interfering RNA and Anticancer Drugs: A Therapeutic Approach for Combating Cancer. 2018 Enzymes
Development of a novel ion-pairing UPLC method with cation-exchange solid-phase extraction for determination of free timolol in human plasma. 2018 J Chromatogr B Analyt Technol Biomed Life Sci
Brain Organoids and the Study of Neurodevelopment. 2018 Trends Mol Med
Report of the international conference on manufacturing and testing of pluripotent stem cells. 2018 Biologicals
Improving Gene Editing Outcomes in Human Hematopoietic Stem and Progenitor Cells by Temporal Control of DNA Repair. 2018 Stem Cells
Fiber-based fluorescence lifetime imaging of recellularization processes on vascular tissue constructs. 2018 J Biophotonics
Human iPSC-Derived Natural Killer Cells Engineered with Chimeric Antigen Receptors Enhance Anti-tumor Activity. 2018 Cell Stem Cell
Concise Review: Human Pluripotent Stem Cells to Produce Cell-Based Cancer Immunotherapy. 2018 Stem Cells
Potential use of stem cells as a therapy for cystinosis. 2018 Pediatr Nephrol
Development and validation of a simplified method to generate human microglia from pluripotent stem cells. 2018 Mol Neurodegener
NKX3-1 is required for induced pluripotent stem cell reprogramming and can replace OCT4 in mouse and human iPSC induction. 2018 Nat Cell Biol
Branched-chain amino acid depletion conditions bone marrow for hematopoietic stem cell transplantation avoiding amino acid imbalance-associated toxicity. 2018 Exp Hematol
De novo formation of the biliary system by TGFbeta-mediated hepatocyte transdifferentiation. 2018 Nature
Protein motion in the nucleus: from anomalous diffusion to weak interactions. 2018 Biochem Soc Trans
Single Molecule Imaging in Live Embryos Using Lattice Light-Sheet Microscopy. 2018 Methods Mol Biol
Recent evidence that TADs and chromatin loops are dynamic structures. 2018 Nucleus
Detailed Visual Cortical Responses Generated by Retinal Sheet Transplants in Rats with Severe Retinal Degeneration. 2018 J Neurosci
SoxB1 Activity Regulates Sensory Neuron Regeneration, Maintenance, and Function in Planarians. 2018 Dev Cell
Fixation, Processing, and Immunofluorescent Labeling of Whole Mount Planarians. 2018 Methods Mol Biol
High density placental mesenchymal stromal cells provide neuronal preservation and improve motor function following in utero treatment of ovine myelomeningocele. 2018 J Pediatr Surg
Parasitic helminths induce fetal-like reversion in the intestinal stem cell niche. 2018 Nature
The intestinal epithelial response to damage. 2018 Sci China Life Sci

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