Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
N-terminal deletion of specific phosphorylation sites on PHOX2B disrupts the formation of enteric neurons in vivo. 2021 Am J Physiol Gastrointest Liver Physiol
The Rhox gene cluster suppresses germline LINE1 transposition. 2021 Proc Natl Acad Sci U S A
In vitro safety "clinical trial" of the cardiac liability of drug polytherapy. 2021 Clin Transl Sci
Successful SCID gene therapy in infant with disseminated BCG. 2021 J Allergy Clin Immunol Pract
Inhibition of prostaglandin-degrading enzyme 15-PGDH rejuvenates aged muscle mass and strength. 2021 Science
Allogeneic human neural stem cells for improved therapeutic delivery to peritoneal ovarian cancer. 2021 Stem Cell Res Ther
SARS-CoV-2 infection of primary human lung epithelium for COVID-19 modeling and drug discovery. 2021 Cell Rep
Harmine inhibits breast cancer cell migration and invasion by inducing the degradation of Twist1. 2021 PLoS One
Interneuron Dysfunction in a New Mouse Model of SCN1A GEFS. 2021 eNeuro
Epigenetic silencing directs expression heterogeneity of stably integrated multi-transcript unit genetic circuits. 2021 Sci Rep
Therapeutic implications of transplanted-cell death. 2021 Nat Biomed Eng
Fabrication of 3D Cardiac Microtissue Arrays using Human iPSC-Derived Cardiomyocytes, Cardiac Fibroblasts, and Endothelial Cells. 2021 J Vis Exp
Pharmacological reversal of synaptic and network pathology in human MECP2-KO neurons and cortical organoids. 2021 EMBO Mol Med
Human neural stem cell-derived extracellular vesicles mitigate hallmarks of Alzheimer's disease. 2021 Alzheimers Res Ther
ApoE-Isoform-Dependent SARS-CoV-2 Neurotropism and Cellular Response. 2021 Cell Stem Cell
Inflammation-driven deaminase deregulation fuels human pre-leukemia stem cell evolution. 2021 Cell Rep
Selective antisense oligonucleotide inhibition of human IRF4 prevents malignant myeloma regeneration via cell cycle disruption. 2021 Cell Stem Cell
Guidelines for reporting single-cell RNA-seq experiments. 2020 Nat Biotechnol
In Vitro Safety "Clinical Trial" of the Cardiac Liability of Hydroxychloroquine and Azithromycin as COVID19 Polytherapy. 2020 bioRxiv
Tissue Stem Cells: Architects of Their Niches. 2020 Cell Stem Cell
Neural Stem Cells Improve the Delivery of Oncolytic Chimeric Orthopoxvirus in a Metastatic Ovarian Cancer Model. 2020 Mol Ther Oncolytics
C9orf72 in myeloid cells suppresses STING-induced inflammation. 2020 Nature
Cell-Based Therapy for Canavan Disease Using Human iPSC-Derived NPCs and OPCs. 2020 Adv Sci (Weinh)
Modeling Human Cytomegalovirus-Induced Microcephaly in Human iPSC-Derived Brain Organoids. 2020 Cell Rep Med
Differential susceptibility of retinal ganglion cell subtypes in acute and chronic models of injury and disease. 2020 Sci Rep
Rapid bacterial detection and antibiotic susceptibility testing in whole blood using one-step, high throughput blood digital PCR. 2020 Lab Chip
Optimization of a syngeneic murine model of bone metastasis. 2020 J Bone Oncol
Delineating the early transcriptional specification of the mammalian trachea and esophagus. 2020 Elife
Foxp1 Regulates Neural Stem Cell Self-Renewal and Bias Toward Deep Layer Cortical Fates. 2020 Cell Rep
A Human Skeletal Muscle Atlas Identifies the Trajectories of Stem and Progenitor Cells across Development and from Human Pluripotent Stem Cells. 2020 Cell Stem Cell
Pluripotent Stem Cell-Based Organoid Technologies for Developing Next-Generation Vision Restoration Therapies of Blindness. 2020 J Ocul Pharmacol Ther
Chemical Elements in Electronic Cigarette Solvents and Aerosols Inhibit Mitochondrial Reductases and Induce Oxidative Stress. 2020 Nicotine Tob Res
Extracellular Vesicles for the Treatment of Radiation-Induced Normal Tissue Toxicity in the Lung. 2020 Front Oncol
Immune and Inflammatory Determinants Underlying Alzheimer's Disease Pathology. 2020 J Neuroimmune Pharmacol
When glia meet induced pluripotent stem cells (iPSCs). 2020 Mol Cell Neurosci
Grading TESI: Crypt and villus formation in tissue-engineered small intestine alters with stem/progenitor cell source. 2020 Am J Physiol Gastrointest Liver Physiol
Mixed chimerism and acceptance of kidney transplants after immunosuppressive drug withdrawal. 2020 Sci Transl Med
Specific targeting of ovarian tumor-associated macrophages by large, anionic nanoparticles. 2020 Proc Natl Acad Sci U S A
SUMOylation of E2F1 Regulates Expression of EZH2. 2020 Cancer Res
Fat grafting rescues radiation-induced joint contracture. 2020 Stem Cells
Northstar enables automatic classification of known and novel cell types from tumor samples. 2020 Sci Rep
mTOR signaling regulates the morphology and migration of outer radial glia in developing human cortex. 2020 Elife
Engineering CAR T Cells to Target the HIV Reservoir. 2020 Front Cell Infect Microbiol
Articular cartilage regeneration by activated skeletal stem cells. 2020 Nat Med
Mutations in Spliceosomal Genes PPIL1 and PRP17 Cause Neurodegenerative Pontocerebellar Hypoplasia with Microcephaly. 2020 Neuron
Surviving Lambs with Myelomeningocele Repaired in utero with Placental Mesenchymal Stromal Cells for 6 Months: A Pilot Study. 2020 Fetal Diagn Ther
Interleukin 7 receptor is required for myeloid cell homeostasis and reconstitution by hematopoietic stem cells. 2020 Exp Hematol
A new anabolic compound, LLP2A-Ale, reserves periodontal bone loss in mice through augmentation of bone formation. 2020 BMC Pharmacol Toxicol
Virus-specific T-cell therapies for patients with primary immune deficiency. 2020 Blood
Tumor necrosis factor overcomes immune evasion in p53-mutant medulloblastoma. 2020 Nat Neurosci

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