Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
Co-grafts of Human Embryonic Stem Cell Derived Retina Organoids and Retinal Pigment Epithelium for Retinal Reconstruction in Immunodeficient Retinal Degenerate Royal College of Surgeons Rats. 2021 Front Neurosci
Preventing Engrailed-1 activation in fibroblasts yields wound regeneration without scarring. 2021 Science
Development of selective bispecific Wnt mimetics for bone loss and repair. 2021 Nat Commun
Long-term safety evaluation of placental mesenchymal stromal cells for in utero repair of myelomeningocele in a novel ovine model. 2021 J Pediatr Surg
Placental Mesenchymal Stromal Cells: Preclinical Safety Evaluation for Fetal Myelomeningocele Repair. 2021 J Surg Res
Efficacy of clinical-grade human placental mesenchymal stromal cells in fetal ovine myelomeningocele repair. 2021 J Pediatr Surg
A Novel Model of Fetal Spinal Cord Exposure Allowing for Long-Term Postnatal Survival. 2021 Fetal Diagn Ther
Minimizing the risk of occupational Q fever exposure: A protocol for ensuring Coxiella burnetii-negative pregnant ewes are used for medical research. 2021 Lab Anim
Human limbal epithelial stem cell regulation, bioengineering and function. 2021 Prog Retin Eye Res
Limbal stem cell diseases. 2021 Exp Eye Res
Wnt signaling activation: targets and therapeutic opportunities for stem cell therapy and regenerative medicine. 2021 RSC Chem Biol
Bioprinting of dual ECM scaffolds encapsulating limbal stem/progenitor cells in active and quiescent statuses. 2021 Biofabrication
Wnt6 plays a complex role in maintaining human limbal stem/progenitor cells. 2021 Sci Rep
Signaling Pathways That Regulate Normal and Aberrant Red Blood Cell Development. 2021 Genes (Basel)
Deep Learning-Assisted Multiphoton Microscopy to Reduce Light Exposure and Expedite Imaging in Tissues With High and Low Light Sensitivity. 2021 Transl Vis Sci Technol
The Epithelial-Mesenchymal Transcription Factor SNAI1 Represses Transcription of the Tumor Suppressor miRNA let-7 in Cancer. 2021 Cancers (Basel)
Long-Term Hypoxia Maintains a State of Dedifferentiation and Enhanced Stemness in Fetal Cardiovascular Progenitor Cells. 2021 Int J Mol Sci
Superporous agarose scaffolds for encapsulation of adult human islets and human stem-cell-derived beta cells for intravascular bioartificial pancreas applications. 2021 J Biomed Mater Res A
Biophysical matrix cues from the regenerating niche direct muscle stem cell fate in engineered microenvironments. 2021 Biomaterials
Secretomes of human pluripotent stem cell-derived smooth muscle cell progenitors upregulate extracellular matrix metabolism in the lower urinary tract and vagina. 2021 Stem Cell Res Ther
Modeling preeclampsia using human induced pluripotent stem cells. 2021 Sci Rep
Advances in Pancreatic Islet Transplantation Sites for the Treatment of Diabetes. 2021 Front Endocrinol (Lausanne)
Freshly Thawed Cryobanked Human Neural Stem Cells Engraft within Endogenous Neurogenic Niches and Restore Cognitive Function after Chronic Traumatic Brain Injury. 2021 J Neurotrauma
Non-invasive intradermal imaging of cystine crystals in cystinosis. 2021 PLoS One
peri-Adventitial delivery of smooth muscle cells in porous collagen scaffolds for treatment of experimental abdominal aortic aneurysm. 2021 Biomater Sci
Upregulation of Vitamin C Transporter Functional Expression in 5xFAD Mouse Intestine. 2021 Nutrients
Normal IgH Repertoire Diversity in an Infant with ADA Deficiency After Gene Therapy. 2021 J Clin Immunol
Reliable generation of glial enriched progenitors from human fibroblast-derived iPSCs. 2021 Stem Cell Res
Patient-derived glial enriched progenitors repair functional deficits due to white matter stroke and vascular dementia in rodents. 2021 Sci Transl Med
Autologous Ex Vivo Lentiviral Gene Therapy for Adenosine Deaminase Deficiency. 2021 N Engl J Med
A Human Pleiotropic Multiorgan Condition Caused by Deficient Wnt Secretion. 2021 N Engl J Med
Immune Protection of Stem Cell-Derived Islet Cell Therapy for Treating Diabetes. 2021 Front Endocrinol (Lausanne)
Mesenchymal Stromal Cells Regulate Sialylations of N-Glycans, Affecting Cell Migration and Survival. 2021 Int J Mol Sci
IFNgamma Is Critical for CAR T Cell-Mediated Myeloid Activation and Induction of Endogenous Immunity. 2021 Cancer Discov
Mitochondria as Playmakers of CAR T-cell Fate and Longevity. 2021 Cancer Immunol Res
Deep immune profiling reveals targetable mechanisms of immune evasion in immune checkpoint inhibitor-refractory glioblastoma. 2021 J Immunother Cancer
CRISPR Screening of CAR T Cells and Cancer Stem Cells Reveals Critical Dependencies for Cell-Based Therapies. 2021 Cancer Discov
Network-based screen in iPSC-derived cells reveals therapeutic candidate for heart valve disease. 2021 Science
ATF6 is essential for human cone photoreceptor development. 2021 Proc Natl Acad Sci U S A
A bioinspired and chemically defined alternative to dimethyl sulfoxide for the cryopreservation of human hematopoietic stem cells. 2021 Bone Marrow Transplant
Retinal organoids on-a-chip: a micro-millifluidic bioreactor for long-term organoid maintenance. 2021 Lab Chip
Allogeneic human neural stem cells for improved therapeutic delivery to peritoneal ovarian cancer. 2021 Stem Cell Res Ther
Enhancing proteasomal processing improves survival for a peptide vaccine used to treat glioblastoma. 2021 Sci Transl Med
Biomaterial-based immunoengineering to fight COVID-19 and infectious diseases. 2021 Matter
Application of lung microphysiological systems to COVID-19 modeling and drug discovery: a review. 2021 Biodes Manuf
N-terminal deletion of specific phosphorylation sites on PHOX2B disrupts the formation of enteric neurons in vivo. 2021 Am J Physiol Gastrointest Liver Physiol
The Rhox gene cluster suppresses germline LINE1 transposition. 2021 Proc Natl Acad Sci U S A
In vitro safety "clinical trial" of the cardiac liability of drug polytherapy. 2021 Clin Transl Sci
Successful SCID gene therapy in infant with disseminated BCG. 2021 J Allergy Clin Immunol Pract
Inhibition of prostaglandin-degrading enzyme 15-PGDH rejuvenates aged muscle mass and strength. 2021 Science

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