Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
A bioactive material with dual integrin-targeting ligands regulates specific endogenous cell adhesion and promotes vascularized bone regeneration in adult and fetal bone defects. 2023 Bioact Mater
Advancing preclinical models of psychiatric disorders with human brain organoid cultures. 2022 Mol Psychiatry
The role of BMP4 signaling in trophoblast emergence from pluripotency. 2022 Cell Mol Life Sci
Recent advancements and future requirements in vascularization of cortical organoids. 2022 Front Bioeng Biotechnol
CDK12 is hyperactivated and a synthetic-lethal target in BRAF-mutated melanoma. 2022 Nat Commun
Proteomic analysis of the actin cortex in interphase and mitosis. 2022 J Cell Sci
High-throughput characterization of the role of non-B DNA motifs on promoter function. 2022 Cell Genom
Modeling Effects of Immunosuppressive Drugs on Human Hearts Using Induced Pluripotent Stem Cell-Derived Cardiac Organoids and Single-Cell RNA Sequencing. 2022 Circulation
Treatment of a genetic brain disease by CNS-wide microglia replacement. 2022 Sci Transl Med
Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation. 2022 Cell
Ensembles of endothelial and mural cells promote angiogenesis in prenatal human brain. 2022 Cell
Impact of pre-existing chronic viral infection and reactivation on the development of long COVID. 2022 J Clin Invest
Absence of microglia promotes diverse pathologies and early lethality in Alzheimer's disease mice. 2022 Cell Rep
Piezo1 regulates cholesterol biosynthesis to influence neural stem cell fate during brain development. 2022 J Gen Physiol
Integration of single-cell transcriptomes and biological function reveals distinct behavioral patterns in bone marrow endothelium. 2022 Nat Commun
Lymphangiocrine signals are required for proper intestinal repair after cytotoxic injury. 2022 Cell Stem Cell
IL-23 signaling prevents ferroptosis-driven renal immunopathology during candidiasis. 2022 Nat Commun
Piezo1-Regulated Mechanotransduction Controls Flow-Activated Lymphatic Expansion. 2022 Circ Res
Biomarkers of in vivo limbal stem cell function. 2022 Ocul Surf
Cell Morphology as an In Vivo Parameter for the Diagnosis of Limbal Stem Cell Deficiency. 2022 Cornea
Comment on: Long-Term Outcome After Superficial Keratectomy of the Abnormal Epithelium for Partial Limbal Stem Cell Deficiency. 2022 Am J Ophthalmol
Cytokeratin 13 Is a New Biomarker for the Diagnosis of Limbal Stem Cell Deficiency. 2022 Cornea
Tumor-Localized Administration of alpha-GalCer to Recruit Invariant Natural Killer T Cells and Enhance Their Antitumor Activity against Solid Tumors. 2022 Int J Mol Sci
Interleukin 15 in Cell-Based Cancer Immunotherapy. 2022 Int J Mol Sci
A scalable organoid model of human autosomal dominant polycystic kidney disease for disease mechanism and drug discovery. 2022 Cell Stem Cell
Phase 1/1b Study of T-allo10 Infusion after HLA-Partially Matched αβ depleted-HSCT in Children and Young Adults with Hematologic Malignancies: Preliminary Results. 2022 Transplantation and Cellular Therapy
The endogenous progenitor response following traumatic brain injury: a target for cell therapy paradigms. 2022 Neural Regen Res
Online seminars as an information source for direct-to-consumer stem cell therapy. 2022 Regen Med
Dose-dependent thresholds of dexamethasone destabilize CAR T-cell treatment efficacy. 2022 PLoS Comput Biol
Off-the-shelf, steroid-resistant, IL13Ralpha2-specific CAR T cells for treatment of glioblastoma. 2022 Neuro Oncol
Spatial organization of heterogeneous immunotherapy target antigen expression in high-grade glioma. 2022 Neoplasia
Altered adult neurogenesis and gliogenesis in patients with mesial temporal lobe epilepsy. 2022 Nat Neurosci
Lifelong single-cell profiling of cranial neural crest diversification in zebrafish. 2022 Nat Commun
Undifferentiated Induced Pluripotent Stem Cells as a Genetic Model for Nonalcoholic Fatty Liver Disease. 2022 Cell Mol Gastroenterol Hepatol
Early investigations into improving bowel and bladder function in fetal ovine myelomeningocele repair. 2022 J Pediatr Surg
Impact of Gestational Age on Neuroprotective Function of Placenta-Derived Mesenchymal Stromal Cells. 2022 J Surg Res
Engineering Extracellular Microenvironment for Tissue Regeneration. 2022 Bioengineering (Basel)
Spina Bifida: A Review of the Genetics, Pathophysiology and Emerging Cellular Therapies. 2022 J Dev Biol
Engineered extracellular vesicles with high collagen-binding affinity present superior in situ retention and therapeutic efficacy in tissue repair. 2022 Theranostics
The Prospects for Retinal Organoids in Treatment of Retinal Diseases. 2022 Asia Pac J Ophthalmol (Phila)
A randomized placebo-controlled phase 3 study of mesenchymal stem cells induced to secrete high levels of neurotrophic factors in amyotrophic lateral sclerosis. 2022 Muscle Nerve
Brain organoids, consciousness, ethics and moral status. 2022 Semin Cell Dev Biol
c-JUN inhibits mTORC2 and glucose uptake to promote self-renewal and obesity. 2022 iScience
Microcarrier-Based Culture of Human Pluripotent Stem-Cell-Derived Retinal Pigmented Epithelium. 2022 Bioengineering (Basel)
Targeting Epigenetic Modifiers of Tumor Plasticity and Cancer Stem Cell Behavior. 2022 Cells
Erratum. 2022 Muscle Nerve
Targeting Immunosuppressive Tumor-Associated Macrophages Using Innate T Cells for Enhanced Antitumor Reactivity. 2022 Cancers (Basel)
An Ex Vivo 3D Tumor Microenvironment-Mimicry Culture to Study TAM Modulation of Cancer Immunotherapy. 2022 Cells
DYNC1LI2 regulates localization of the chaperone-mediated autophagy receptor LAMP2A and improves cellular homeostasis in cystinosis. 2022 Autophagy
Collateral Arteriogenesis Involves a Sympathetic Denervation That Is Associated With Abnormal alpha-Adrenergic Signaling and a Transient Loss of Vascular Tone. 2022 Front Cardiovasc Med

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