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High-Efficiency, Selection-free Gene Repair in Airway Stem Cells from Cystic Fibrosis Patients Rescues CFTR Function in Differentiated Epithelia. |
2019 |
Cell Stem Cell |
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Human iPSCs can be differentiated into notochordal cells that reduce intervertebral disc degeneration in a porcine model. |
2019 |
Theranostics |
|
Spinal subpial delivery of AAV9 enables widespread gene silencing and blocks motoneuron degeneration in ALS. |
2019 |
Nat Med |
|
Antibody Conditioning Enables MHC-Mismatched Hematopoietic Stem Cell Transplants and Organ Graft Tolerance. |
2019 |
Cell Stem Cell |
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Development of Hematopoietic Stem Cell-Engineered Invariant Natural Killer T Cell Therapy for Cancer. |
2019 |
Cell Stem Cell |
|
Bovine pericardial extracellular matrix niche modulates human aortic endothelial cell phenotype and function. |
2019 |
Sci Rep |
|
Automated Design of Pluripotent Stem Cell Self-Organization. |
2019 |
Cell Syst |
|
V2a interneuron differentiation from mouse and human pluripotent stem cells. |
2019 |
Nat Protoc |
|
In Utero Treatment of Myelomeningocele with Placental Mesenchymal Stromal Cells - Selection of an Optimal Cell Line in Preparation for Clinical Trials. |
2019 |
J Pediatr Surg |
|
Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy. |
2019 |
Nature |
|
Establishing Cerebral Organoids as Models of Human-Specific Brain Evolution. |
2019 |
Cell |
|
Modeling Spatial Correlation of Transcripts with Application to Developing Pancreas. |
2019 |
Sci Rep |
|
Precise in vivo genome editing via single homology arm donor mediated intron-targeting gene integration for genetic disease correction. |
2019 |
Cell Res |
|
Circulating tumor cells exhibit metastatic tropism and reveal brain metastasis drivers. |
2019 |
Cancer Discov |
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An Improved Two-Step Protocol for Trophoblast Differentiation of Human Pluripotent Stem Cells. |
2019 |
Curr Protoc Stem Cell Biol |
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Classification of Limbal Stem Cell Deficiency Using Clinical and Confocal Grading. |
2019 |
Cornea |
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The application of human amniotic membrane in the surgical management of limbal stem cell deficiency. |
2019 |
Ocul Surf |
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Comparison of endothelial keratoplasty techniques in patients with prior glaucoma surgery - a case-matched study. |
2019 |
Am J Ophthalmol |
|
Wnt Signaling Is Required for the Maintenance of Human Limbal Stem/Progenitor Cells In Vitro. |
2019 |
Invest Ophthalmol Vis Sci |
|
Diagnostic criteria for limbal stem cell deficiency before surgical intervention-A systematic literature review and analysis. |
2019 |
Surv Ophthalmol |
|
Mesenchymal Stem Cells Reduce Corneal Fibrosis and Inflammation via Extracellular Vesicle-Mediated Delivery of miRNA. |
2019 |
Stem Cells Transl Med |
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Notch Inhibition Prevents Differentiation of Human Limbal Stem/Progenitor Cells in vitro. |
2019 |
Sci Rep |
|
Human induced pluripotent stem cell line with genetically encoded fluorescent voltage indicator generated via CRISPR for action potential assessment post-cardiogenesis. |
2019 |
Stem Cells |
|
Chronic myelogenous leukemia stem cells require cell-autonomous pleiotrophin signaling. |
2019 |
J Clin Invest |
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PTPsigma inhibitors promote hematopoietic stem cell regeneration. |
2019 |
Nat Commun |
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Phenotypic Variation Between Stromal Cells Differentially Impacts Engineered Cardiac Tissue Function. |
2019 |
Tissue Eng Part A |
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Determining the pharmacokinetics of nicotinic drugs in the endoplasmic reticulum using biosensors. |
2019 |
J Gen Physiol |
|
Development of a Chimeric Model to Study and Manipulate Human Microglia In Vivo. |
2019 |
Neuron |
|
Fiber-based platform for synchronous imaging of endogenous and exogenous fluorescence of biological tissue. |
2019 |
Opt Lett |
|
Complex Oscillatory Waves Emerging from Cortical Organoids Model Early Human Brain Network Development. |
2019 |
Cell Stem Cell |
|
Transposable Elements, Inflammation, and Neurological Disease. |
2019 |
Front Neurol |
|
Fluorous-Soluble Metal Chelate for Sensitive Fluorine-19 Magnetic Resonance Imaging Nanoemulsion Probes. |
2019 |
ACS Nano |
|
Paramagnetic Fluorinated Nanoemulsions for in vivo F-19 MRI. |
2019 |
Mol Imaging Biol |
|
Brain Organoids as Tools for Modeling Human Neurodevelopmental Disorders. |
2019 |
Physiology (Bethesda) |
|
Anti-human CD117 antibody-mediated bone marrow niche clearance in nonhuman primates and humanized NSG mice. |
2019 |
Blood |
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Anti-CD117 antibody depletes normal and myelodysplastic syndrome human hematopoietic stem cells in xenografted mice. |
2019 |
Blood |
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Selective hematopoietic stem cell ablation using CD117-antibody-drug-conjugates enables safe and effective transplantation with immunity preservation. |
2019 |
Nat Commun |
|
Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-beta in iPSC-Derived Alzheimer's Disease Neurons. |
2019 |
Cell Stem Cell |
|
Brain organoids as a model system for human neurodevelopment and disease. |
2019 |
Semin Cell Dev Biol |
|
Effect of inoculum density on human-induced pluripotent stem cell expansion in 3D bioreactors. |
2019 |
Cell Prolif |
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Online measurement of oxygen enables continuous noninvasive evaluation of human-induced pluripotent stem cell (hiPSC) culture in a perfused 3D hollow-fiber bioreactor. |
2019 |
J Tissue Eng Regen Med |
|
Combinatorial targeting of cancer bone metastasis using mRNA engineered stem cells. |
2019 |
EBioMedicine |
|
Genomic Profiling of BDE-47 Effects on Human Placental Cytotrophoblasts. |
2019 |
Toxicol Sci |
|
CRISPR-mediated activation of a promoter or enhancer rescues obesity caused by haploinsufficiency. |
2019 |
Science |
|
Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation. |
2019 |
Nature |
|
Evidence for DNA-mediated nuclear compartmentalization distinct from phase separation. |
2019 |
Elife |
|
Spinal Angulation: A Limitation of the Fetal Lamb Model of Myelomeningocele. |
2019 |
Fetal Diagn Ther |
|
Cardiac fibrosis: potential therapeutic targets. |
2019 |
Transl Res |
|
Harnessing the versatility of PLGA nanoparticles for targeted Cre-mediated recombination. |
2019 |
Nanomedicine |
|
Enhanced Delivery of Oncolytic Adenovirus by Neural Stem Cells for Treatment of Metastatic Ovarian Cancer. |
2019 |
Mol Ther Oncolytics |
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