Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
Manufacturing considerations for producing and assessing decellularized extracellular matrix hydrogels. 2020 Methods
Dose optimization of decellularized skeletal muscle extracellular matrix hydrogels for improving perfusion and subsequent validation in an aged hindlimb ischemia model. 2020 Biomater Sci
Unleashing the cure: Overcoming persistent obstacles in the translation and expanded use of hematopoietic stem cell-based therapies. 2020 Stem Cells Translational Medicine
Long-term eradication of extranodal natural killer/T-cell lymphoma, nasal type, by induced pluripotent stem cell-derived Epstein-Barr virus-specific rejuvenated T cells in vivo. 2020 Haematologica
Germline development in rat revealed by visualization and deletion of Prdm14. 2020 Development
Compensation of Disabled Organogeneses in Genetically Modified Pig Fetuses by Blastocyst Complementation. 2020 Stem Cell Reports
Aberrant Development Corrected in Adult-Onset Huntington's Disease iPSC-Derived Neuronal Cultures via WNT Signaling Modulation. 2020 Stem Cell Reports
Long-term ex vivo expansion of mouse hematopoietic stem cells. 2020 Nat Protoc
Resolving the 3D Landscape of Transcription-Linked Mammalian Chromatin Folding. 2020 Mol Cell
Adeno-Associated Virus and Hematopoietic Stem Cells: The Potential of Adeno-Associated Virus Hematopoietic Stem Cells in Genetic Medicines. 2020 Hum Gene Ther
A critical look: Challenges in differentiating human pluripotent stem cells into desired cell types and organoids. 2020 Wiley Interdiscip Rev Dev Biol
An engineered cell-laden adhesive hydrogel promotes craniofacial bone tissue regeneration in rats. 2020 Sci Transl Med
An intrinsic, label-free signal for identifying stem cell-derived cardiomyocyte subtype. 2020 Stem Cells
Fat grafting rescues radiation-induced joint contracture. 2020 Stem Cells
Guided nuclear exploration increases CTCF target search efficiency. 2020 Nat Chem Biol
Biomaterials for tissue repair. 2019 Science
Preliminary Results of a Phase 1/2 Clinical Study of Zinc Finger Nuclease-Mediated Editing of BCL11A in Autologous Hematopoietic Stem Cells for Transfusion-Dependent Beta Thalassemia 2019 Blood
Chasing Mavericks: The quest for defining developmental waves of hematopoiesis. 2019 Curr Top Dev Biol
The lymphoid-associated interleukin 7 receptor (IL7R) regulates tissue-resident macrophage development. 2019 Development
Biological process activity transformation of single cell gene expression for cross-species alignment. 2019 Nat Commun
Using the Inducible Caspase-9 Suicide-Safeguard System with iPSC and Bioluminescent Tracking. 2019 Methods Mol Biol
Human iPSC Generation from Antigen-Specific T Cells. 2019 Methods Mol Biol
Generation of functional lungs via conditional blastocyst complementation using pluripotent stem cells. 2019 Nat Med
Single cell analysis of human foetal liver captures the transcriptional profile of hepatobiliary hybrid progenitors. 2019 Nat Commun
Anephrogenic phenotype induced by SALL1 gene knockout in pigs. 2019 Sci Rep
Improved Computational Identification of Drug Response Using Optical Measurements of Human Stem Cell Derived Cardiomyocytes in Microphysiological Systems. 2019 Front Pharmacol
Use of polyvinyl alcohol for chimeric antigen receptor T-cell expansion. 2019 Exp Hematol
Hematopoietic stem cell-independent hematopoiesis and the origins of innate-like B lymphocytes. 2019 Development
Efficient Differentiation of Human Pluripotent Stem Cells into Liver Cells. 2019 J Vis Exp
Antibody Conditioning Enables MHC-Mismatched Hematopoietic Stem Cell Transplants and Organ Graft Tolerance. 2019 Cell Stem Cell
CTCF sites display cell cycle-dependent dynamics in factor binding and nucleosome positioning. 2019 Genome Res
Determining cellular CTCF and cohesin abundances to constrain 3D genome models. 2019 Elife
Distinct Classes of Chromatin Loops Revealed by Deletion of an RNA-Binding Region in CTCF. 2019 Mol Cell
Evaluating phase separation in live cells: diagnosis, caveats, and functional consequences. 2019 Genes Dev
Atoh1 Directs Regeneration and Functional Recovery of the Mature Mouse Vestibular System. 2019 Cell Rep
An Improved Two-Step Protocol for Trophoblast Differentiation of Human Pluripotent Stem Cells. 2019 Curr Protoc Stem Cell Biol
Spinal subpial delivery of AAV9 enables widespread gene silencing and blocks motoneuron degeneration in ALS. 2019 Nat Med
Primed mesenchymal stem cells package exosomes with metabolites associated with immunomodulation. 2019 Biochem Biophys Res Commun
High-Efficiency, Selection-free Gene Repair in Airway Stem Cells from Cystic Fibrosis Patients Rescues CFTR Function in Differentiated Epithelia. 2019 Cell Stem Cell
Human iPSCs can be differentiated into notochordal cells that reduce intervertebral disc degeneration in a porcine model. 2019 Theranostics
Development of Hematopoietic Stem Cell-Engineered Invariant Natural Killer T Cell Therapy for Cancer. 2019 Cell Stem Cell
Bovine pericardial extracellular matrix niche modulates human aortic endothelial cell phenotype and function. 2019 Sci Rep
Automated Design of Pluripotent Stem Cell Self-Organization. 2019 Cell Syst
V2a interneuron differentiation from mouse and human pluripotent stem cells. 2019 Nat Protoc
In Utero Treatment of Myelomeningocele with Placental Mesenchymal Stromal Cells - Selection of an Optimal Cell Line in Preparation for Clinical Trials. 2019 J Pediatr Surg
Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy. 2019 Nature
Establishing Cerebral Organoids as Models of Human-Specific Brain Evolution. 2019 Cell
Modeling Spatial Correlation of Transcripts with Application to Developing Pancreas. 2019 Sci Rep
Precise in vivo genome editing via single homology arm donor mediated intron-targeting gene integration for genetic disease correction. 2019 Cell Res
Circulating tumor cells exhibit metastatic tropism and reveal brain metastasis drivers. 2019 Cancer Discov

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