| Human stem cell-derived GABAergic interneuron development reveals early emergence of subtype diversity and gradual electrochemical maturation. |
2025 |
Neuron |
| Identification and engineering of potent bispecific antibodies that protect against herpes simplex virus recurrent disease. |
2025 |
Cell Rep |
| Identification of CD84 as a potent survival factor in acute myeloid leukemia. |
2025 |
J Clin Invest |
| Identification of novel genetic mutations for the treatment prognostication of canine lymphoma. |
2025 |
NPJ Precis Oncol |
| IGF2BP3 redirects glycolytic flux to promote one-carbon metabolism and RNA methylation. |
2025 |
Cell Rep |
| IgG autoantibodies in bullous pemphigoid induce a pathogenic MyD88-dependent pro-inflammatory response in keratinocytes. |
2025 |
Nat Commun |
| Immunotherapy-related cognitive impairment after CAR T cell therapy in mice. |
2025 |
Cell |
| Implantation of engineered adipocytes suppresses tumor progression in cancer models. |
2025 |
Nat Biotechnol |
| In utero lipid nanoparticle delivery achieves robust editing in hematopoietic stem cells. |
2025 |
bioRxiv |
| In vivo human embryonic spinal cord atlas validates stem cell-derived human dorsal interneurons and reveals ASD spinal signatures. |
2025 |
bioRxiv |
| Inactivation of Histone Chaperone HIRA Unmasks a Link Between Normal Embryonic Development of Melanoblasts and Maintenance of Adult Melanocyte Stem Cells. |
2025 |
Aging Cell |
| Injectable PLGA Microscaffolds with Laser-Induced Enhanced Microporosity for Nucleus Pulposus Cell Delivery. |
2025 |
Small |
| Integrated Longitudinal Transcriptomic and Proteomic Analysis of the Murine Lung Response to Influenza A Virus. |
2025 |
Am J Respir Cell Mol Biol |
| Integrated single-nuclei and spatial transcriptomic profiling of human sacrococcygeal teratomas reveals heterogeneity in cellular composition and X-chromosome inactivation. |
2025 |
bioRxiv |
| Integrated workflow for analysis of immune enriched spatial proteomic data with IMmuneCite. |
2025 |
Sci Rep |
| Intestinal epithelial PTPN2 limits pathobiont colonization by immune-directed antimicrobial responses. |
2025 |
Gut Microbes |
| Intra-amniotic antisense oligonucleotide treatment improves phenotypes in preclinical models of spinal muscular atrophy. |
2025 |
Sci Transl Med |
| Intraputaminal Delivery of Adeno-Associated Virus Serotype 2-Glial Cell Line-Derived Neurotrophic Factor in Mild or Moderate Parkinson’s Disease. |
2025 |
Mov Disord |
| Intravenous and intracranial GD2-CAR T cells for H3K27M(+) diffuse midline gliomas. |
2025 |
Nature |
| Intravenous and oral administration of the synthetic RNA drug, TY1, reverses heart failure with preserved ejection fraction in mice. |
2025 |
Basic Res Cardiol |
| Investigational New Drug-enabling studies to use genetically modified mesenchymal stromal cells in patients with critical limb ischemia. |
2025 |
Stem Cells Transl Med |
| Irradiation- and busulfan-free stem cell transplantation in Fanconi anemia using an anti-CD117 antibody: a phase 1b trial. |
2025 |
Nat Med |
| KIF5A downregulation in spinal muscular atrophy links axonal regeneration defects with ALS. |
2025 |
bioRxiv |
| Large language model agents can use tools to perform clinical calculations. |
2025 |
NPJ Digit Med |
| Lentiviral vectors for hematopoietic stem cell gene therapy restore alpha-globin expression in alpha-thalassemia red blood cells. |
2025 |
Cell Rep Med |
| LGR4 is essential for maintaining beta-cell homeostasis through suppression of RANK. |
2025 |
Mol Metab |
| Limbal epithelial cells detected in stage III limbal stem cell deficiency by multimodal anterior segment imaging. |
2025 |
Am J Ophthalmol |
| Lineage tracing of both quiescent G0 and active Hoxb5+ LT-HSCs that actively contribute to homeostatic mouse hematopoiesis. |
2025 |
Proc Natl Acad Sci U S A |
| Lineage-resolved atlas of the developing human cortex. |
2025 |
Nature |
| Local Growth Hormone Facilitates Aging of the Colon Epithelial Microenvironment. |
2025 |
Aging Cell |
| Long noncoding RNA BCYRN1 promotes cardioprotection by enhancing human and murine regulatory T cell dynamics. |
2025 |
J Clin Invest |
| Long-term preservation of muscle function and structure by repeated administration of cardiosphere-derived cells in mdx mice. |
2025 |
Stem Cell Reports |
| Long-Term Safety and Efficacy of Gene Therapy for Adenosine Deaminase Deficiency. |
2025 |
N Engl J Med |
| Lysosomal proteomics reveals mechanisms of neuronal apoE4-associated lysosomal dysfunction. |
2025 |
bioRxiv |
| Measurement and clinical interpretation of CRISPR off-targets. |
2025 |
Nat Genet |
| MeCP2 regulates telencephalic development in human cerebral organoids. |
2025 |
Cell Rep |
| Meningeal solitary fibrous tumor cell states phenocopy cerebral vascular development and homeostasis. |
2025 |
Neuro Oncol |
| Menthol, a consumer product additive, adversely affects human embryonic stem cells via activation of TRPM8 and TRPA1 channels. |
2025 |
Stem Cells Transl Med |
| Microglia regulate GABAergic neurogenesis in prenatal human brain through IGF1. |
2025 |
Nature |
| Microgliopathy as a primary mediator of neuronal death in models of Friedreich’s Ataxia. |
2025 |
Nat Commun |
| Micropatterning Photoconductive Peptide Assemblies on Stiff and Soft Biomaterial Substrates. |
2025 |
ACS Appl Mater Interfaces |
| Minimally invasive serial collection of cerebrospinal fluid reveals sex-dependent differences in neuroinflammation in a rat model of mild traumatic brain injury. |
2025 |
Brain Behav Immun |
| MitoScribe single-cell molecular recorder logs graded signaling dynamics into mitochondrial DNA. |
2025 |
bioRxiv |
| Modeling glioma intratumoral heterogeneity with primary human neural stem and progenitor cells. |
2025 |
Stem Cell Reports |
| Modulation of the JAK2-STAT3 pathway promotes expansion and maturation of human iPSC-derived myogenic progenitor cells. |
2025 |
Stem Cell Reports |
| Molecular Signatures in Cortical Development. |
2025 |
Annu Rev Neurosci |
| Morphogen-guided neocortical organoids recapitulate regional areal identity and model neurodevelopmental disorder pathology. |
2025 |
bioRxiv |
| Multicenter HFpEF study identifies sex disparity linked with two discrete cardiac proteomic signatures. |
2025 |
bioRxiv |
| MYOD represses gene expression from non-E-box motifs. |
2025 |
Genes Dev |
| Neuroendocrinology and the Genetics of Obesity. |
2025 |
Endocrinology |