| FXYD2 marks and regulates maturity of beta cells via ion channel-mediated signal transduction. |
2025 |
Nat Commun |
| Generating allogeneic CAR-NKT cells for off-the-shelf cancer immunotherapy with genetically engineered HSP cells and feeder-free differentiation culture. |
2025 |
Nat Protoc |
| Generation of a set of genetically modified long QT syndrome induced pluripotent stem cell lines carrying knock-in variants rs120074178 (KCNQ1 c.569G > A; p.Arg190Gln) and rs137854600 (SCN5A c.4865G > A; p.Arg1622Gln) and isogenic control lines. |
2025 |
Stem Cell Res |
| Genome editing with programmable base editors in human cells. |
2025 |
Methods Enzymol |
| GFP-on mouse model for interrogation of in vivo gene editing. |
2025 |
Nat Commun |
| Hematopoietic stem cell gene therapy for the treatment of X-linked agammaglobulinemia. |
2025 |
Mol Ther Methods Clin Dev |
| Highly efficient in vivo hematopoietic stem cell transduction using an optimized self-complementary adeno-associated virus. |
2025 |
Mol Ther Methods Clin Dev |
| HIPPIE: A Multimodal Deep Learning Model for Electrophysiological Classification of Neurons. |
2025 |
bioRxiv |
| Histological signatures map anti-fibrotic factors in mouse and human lungs. |
2025 |
Nature |
| Histone chaperones coupled to DNA replication and transcription control divergent chromatin elements to maintain cell fate. |
2025 |
Genes Dev |
| Human embryo implantation in vitro: a standardized framework for basic research and clinical translation. |
2025 |
Fertil Steril |
| Human stem cell-derived GABAergic interneuron development reveals early emergence of subtype diversity and gradual electrochemical maturation. |
2025 |
Neuron |
| Identification and engineering of potent bispecific antibodies that protect against herpes simplex virus recurrent disease. |
2025 |
Cell Rep |
| Identification of CD84 as a potent survival factor in acute myeloid leukemia. |
2025 |
J Clin Invest |
| Identification of novel genetic mutations for the treatment prognostication of canine lymphoma. |
2025 |
NPJ Precis Oncol |
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2025 |
Cell Rep |
| IgG autoantibodies in bullous pemphigoid induce a pathogenic MyD88-dependent pro-inflammatory response in keratinocytes. |
2025 |
Nat Commun |
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2025 |
Cell |
| Implantation of engineered adipocytes suppresses tumor progression in cancer models. |
2025 |
Nat Biotechnol |
| In utero lipid nanoparticle delivery achieves robust editing in hematopoietic stem cells. |
2025 |
bioRxiv |
| In vivo human embryonic spinal cord atlas validates stem cell-derived human dorsal interneurons and reveals ASD spinal signatures. |
2025 |
bioRxiv |
| Inactivation of Histone Chaperone HIRA Unmasks a Link Between Normal Embryonic Development of Melanoblasts and Maintenance of Adult Melanocyte Stem Cells. |
2025 |
Aging Cell |
| Injectable PLGA Microscaffolds with Laser-Induced Enhanced Microporosity for Nucleus Pulposus Cell Delivery. |
2025 |
Small |
| Integrated Longitudinal Transcriptomic and Proteomic Analysis of the Murine Lung Response to Influenza A Virus. |
2025 |
Am J Respir Cell Mol Biol |
| Integrated single-nuclei and spatial transcriptomic profiling of human sacrococcygeal teratomas reveals heterogeneity in cellular composition and X-chromosome inactivation. |
2025 |
bioRxiv |
| Integrated workflow for analysis of immune enriched spatial proteomic data with IMmuneCite. |
2025 |
Sci Rep |
| Intestinal epithelial PTPN2 limits pathobiont colonization by immune-directed antimicrobial responses. |
2025 |
Gut Microbes |
| Intra-amniotic antisense oligonucleotide treatment improves phenotypes in preclinical models of spinal muscular atrophy. |
2025 |
Sci Transl Med |
| Intraputaminal Delivery of Adeno-Associated Virus Serotype 2-Glial Cell Line-Derived Neurotrophic Factor in Mild or Moderate Parkinson’s Disease. |
2025 |
Mov Disord |
| Intravenous and intracranial GD2-CAR T cells for H3K27M(+) diffuse midline gliomas. |
2025 |
Nature |
| Intravenous and oral administration of the synthetic RNA drug, TY1, reverses heart failure with preserved ejection fraction in mice. |
2025 |
Basic Res Cardiol |
| Investigational New Drug-enabling studies to use genetically modified mesenchymal stromal cells in patients with critical limb ischemia. |
2025 |
Stem Cells Transl Med |
| Irradiation- and busulfan-free stem cell transplantation in Fanconi anemia using an anti-CD117 antibody: a phase 1b trial. |
2025 |
Nat Med |
| KIF5A downregulation in spinal muscular atrophy links axonal regeneration defects with ALS. |
2025 |
bioRxiv |
| Large language model agents can use tools to perform clinical calculations. |
2025 |
NPJ Digit Med |
| Lentiviral vectors for hematopoietic stem cell gene therapy restore alpha-globin expression in alpha-thalassemia red blood cells. |
2025 |
Cell Rep Med |
| LGR4 is essential for maintaining beta-cell homeostasis through suppression of RANK. |
2025 |
Mol Metab |
| Limbal epithelial cells detected in stage III limbal stem cell deficiency by multimodal anterior segment imaging. |
2025 |
Am J Ophthalmol |
| Lineage tracing of both quiescent G0 and active Hoxb5+ LT-HSCs that actively contribute to homeostatic mouse hematopoiesis. |
2025 |
Proc Natl Acad Sci U S A |
| Lineage-resolved atlas of the developing human cortex. |
2025 |
Nature |
| Local Growth Hormone Facilitates Aging of the Colon Epithelial Microenvironment. |
2025 |
Aging Cell |
| Long noncoding RNA BCYRN1 promotes cardioprotection by enhancing human and murine regulatory T cell dynamics. |
2025 |
J Clin Invest |
| Long-term preservation of muscle function and structure by repeated administration of cardiosphere-derived cells in mdx mice. |
2025 |
Stem Cell Reports |
| Long-Term Safety and Efficacy of Gene Therapy for Adenosine Deaminase Deficiency. |
2025 |
N Engl J Med |
| Lysosomal proteomics reveals mechanisms of neuronal apoE4-associated lysosomal dysfunction. |
2025 |
bioRxiv |
| Measurement and clinical interpretation of CRISPR off-targets. |
2025 |
Nat Genet |
| MeCP2 regulates telencephalic development in human cerebral organoids. |
2025 |
Cell Rep |
| Meningeal solitary fibrous tumor cell states phenocopy cerebral vascular development and homeostasis. |
2025 |
Neuro Oncol |
| Menthol, a consumer product additive, adversely affects human embryonic stem cells via activation of TRPM8 and TRPA1 channels. |
2025 |
Stem Cells Transl Med |
| Microglia regulate GABAergic neurogenesis in prenatal human brain through IGF1. |
2025 |
Nature |
