Publications by Grantees

CIRM funding supported the following publications. Click on the publication title for a brief summary of the research and for more information:

Title Year Journal
Non-genetic neuromodulation with graphene optoelectronic actuators for disease models, stem cell maturation, and biohybrid robotics. 2025 Nat Commun
Nuclear receptor 4A1 is critical for neutrophil-dependent pulmonary immunity to Klebsiella pneumoniae infection. 2025 Front Immunol
On the Feasibility of SERS-Based Monitoring of Drug Loading Efficiency in Exosomes for Targeted Delivery. 2025 Biosensors (Basel)
Opposing roles of p38alpha-mediated phosphorylation and PRMT1-mediated arginine methylation in driving TDP-43 proteinopathy. 2025 Cell Rep
Oral Bioavailability of a Noncoding RNA Drug, TY1, That Acts on Macrophages. 2025 J Extracell Biol
Overcoming ovarian cancer resistance and evasion to CAR-T cell therapy by harnessing allogeneic CAR-NKT cells. 2025 Med
p53 enhances DNA repair and suppresses cytoplasmic chromatin fragments and inflammation in senescent cells. 2025 Nat Commun
p95HER2, a truncated form of the HER2 oncoprotein, drives an immunosuppressive program in HER2(+) breast cancer that limits trastuzumab deruxtecan efficacy. 2025 Nat Cancer
Paracrine effect of human stem cell-derived progenitor cells on remodeling of the vagina. 2025 NPJ Regen Med
Pervasive and programmed nucleosome distortion patterns on single mammalian chromatin fibers. 2025 bioRxiv
PHLDA2 promotes breast cancer metastasis by co-opting a developmental program for placental vascular remodeling. 2025 bioRxiv
Phosphorylation of HP1/Swi6 relieves competition with Suv39/Clr4 on nucleosomes and enables H3K9 trimethyl spreading. 2025 Nucleic Acids Res
Postoperative adhesions are abrogated by a sustained-release anti-JUN therapeutic in preclinical models. 2025 Sci Transl Med
Probing DNA damage in Rett syndrome neurons uncovers a role for MECP2 regulation of PARP1. 2025 Stem Cell Reports
Process of radical resection for advanced buccal cancer and the ‘sandwich’ technique for craniomaxillofacial defect repair using an anterolateral thigh chimeric myocutaneous flap. 2025 J Craniomaxillofac Surg
Proof of concept for brain organoid-on-a-chip to create multiple domains in forebrain organoids. 2025 RSC Adv
Proteasome inhibition enhances oncolytic reovirus therapy in multiple myeloma independently of its direct cytotoxic effects. 2025 J Hematol Oncol
Proteome-wide profiling of S-nitrosylated proteins using the SNOTRAP probe and mass spectrometry-based detection. 2025 Nat Protoc
Protocol for deep-learning-driven cell type label transfer in single-cell RNA sequencing data. 2025 STAR Protoc
Protocol for live-cell calcium imaging of human lung microvascular endothelial vessel-on-a-chip model. 2025 STAR Protoc
Protocol for the isolation and characterization of mouse alveolar bone marrow hematopoietic stem cells. 2025 STAR Protoc
Protocol for vibratome sectioning, immunofluorescence, and S-phase labeling of inner ear organoids. 2025 STAR Protoc
Protocol to study ductal progenitor-like cells from the adult human pancreas using 3D suspension and methylcellulose-based culture systems. 2025 STAR Protoc
PSCS: Unified Sharing of Single-Cell Omics Data, Analyses, and Results. 2025 J Proteome Res
PTPN2 Regulates Iron Handling Protein Expression in Inflammatory Bowel Disease Patients and Prevents Iron Deficiency in Mice. 2025 Int J Mol Sci
Rapamycin enhances CAR-T control of HIV replication and reservoir elimination in vivo. 2025 J Clin Invest
Regulatory roles of three-dimensional structures of chromatin domains. 2025 Genome Biol
Reversible proliferative arrest induced by rapid depletion of RNase MRP. 2025 Nat Commun
Safe immunosuppression-resistant pan-cancer immunotherapeutics by velcro-like density-dependent targeting of tumor-associated carbohydrate antigens. 2025 Cell
Safety and tolerability of RPESC-RPE transplantation in patients with dry age-related macular degeneration: Low-dose clinical outcomes. 2025 Cell Stem Cell
Self-Organizing Neural Networks in Organoids Reveal Principles of Forebrain Circuit Assembly. 2025 bioRxiv
Single-Cell Proteomics Reveals Specific Cellular Subtypes in Cardiomyocytes Derived From Human iPSCs and Adult Hearts. 2025 Mol Cell Proteomics
Size and Structural Control of Mechanoluminescent ZnS:Mn(2+) Nanocrystals for Optogenetic Neuromodulation. 2025 ACS Nano
Smed-pou4-2 regulates mechanosensory neuron regeneration and function in planarians. 2025 bioRxiv
Smed-pou4-2 regulates mechanosensory neuron regeneration and function in planarians. 2025 Elife
Smooth muscle cell Piezo1 depletion results in impaired contractile properties in murine small bowel. 2025 Commun Biol
Spatial and Single-Cell Transcriptomics Reveal Keratinocytes as Key Players in Vulvar Lichen Sclerosus Pathogenesis. 2025 J Invest Dermatol
Spatially patterned kidney assembloids recapitulate progenitor self-assembly and enable high-fidelity in vivo disease modeling. 2025 Cell Stem Cell
Spinal Cord Injury in Real Time: Intra-Operative Ultrasound for Acute Phase Examination in Non-Human Primates. 2025 Brain Sci
Stem cell research in space: Advancing regenerative medicine beyond Earth. 2025 Cell Stem Cell
Structural and functional analysis of cancer-associated missense variants in the retinoblastoma protein pocket domain. 2025 J Biol Chem
Suppressing APOE4-induced neural pathologies by targeting the VHL-HIF axis. 2025 Proc Natl Acad Sci U S A
Surface modification of extracellular vesicles with polyoxazolines to enhance their plasma stability and tumor accumulation. 2025 Biomaterials
Systemic deficits in lipid homeostasis promote aging-associated impairments in B cell progenitor development. 2025 Geroscience
T(H)17 cells converted into exT(H)17 cells sustain rheumatoid-like IL-17-independent inflammatory arthritis. 2025 Sci Immunol
Targeting CyclinD1-CDK6 to Mitigate Senescence-Driven Inflammation and Age-Associated Functional Decline. 2025 bioRxiv
The HIV-1 nuclear export complex reveals the role of RNA in CRM1 cargo recognition. 2025 Mol Cell
The Nrf2 Activator CDDO-Imidazole Suppresses Inflammation-Induced Red Blood Cell Alloimmunization. 2025 Antioxidants (Basel)
The nuclear periphery confers repression on H3K9me2-marked genes and transposons to shape cell fate. 2025 Nat Cell Biol
The Proteostasis Network is a Therapeutic Target in Acute Myeloid Leukemia. 2025 Blood