| Suppressing APOE4-induced neural pathologies by targeting the VHL-HIF axis. |
2025 |
Proc Natl Acad Sci U S A |
| Systemic deficits in lipid homeostasis promote aging-associated impairments in B cell progenitor development. |
2025 |
Geroscience |
| T(H)17 cells converted into exT(H)17 cells sustain rheumatoid-like IL-17-independent inflammatory arthritis. |
2025 |
Sci Immunol |
| Targeting CyclinD1-CDK6 to Mitigate Senescence-Driven Inflammation and Age-Associated Functional Decline. |
2025 |
bioRxiv |
| The HIV-1 nuclear export complex reveals the role of RNA in CRM1 cargo recognition. |
2025 |
Mol Cell |
| The Nrf2 Activator CDDO-Imidazole Suppresses Inflammation-Induced Red Blood Cell Alloimmunization. |
2025 |
Antioxidants (Basel) |
| The Proteostasis Network is a Therapeutic Target in Acute Myeloid Leukemia. |
2025 |
Blood |
| The PTPN2 rs1893217 IBD risk allele increases susceptibility to AIEC invasion by a JAK-STAT-CEACAM6 axis. |
2025 |
Gut Microbes |
| The Role of Supraoptic Hypothalamic Arginine Vasopressin Neurons in Aging-Associated Water Balance and Thermoregulatory Deficits. |
2025 |
bioRxiv |
| The single-molecule accessibility landscape of newly replicated mammalian chromatin. |
2025 |
Cell |
| The transcriptional and cellular landscape of cognitive resilience to Alzheimer’s disease. |
2025 |
Front Mol Neurosci |
| The UCSC Genome Browser database: 2025 update. |
2025 |
Nucleic Acids Res |
| Therapeutic genetic restoration through allogeneic brain microglia replacement. |
2025 |
Nature |
| Towards universal modeling of transcript isoform expression levels. |
2025 |
bioRxiv |
| Understanding human embryogenesis by building programmable stem cell-based models. |
2025 |
Trends Cell Biol |
| Upregulated FoxO1 promotes arrhythmogenesis in mice with heart failure and preserved ejection fraction. |
2025 |
Nat Commun |
| VGLL1 contributes to both the transcriptome and epigenome of the developing trophoblast compartment. |
2025 |
bioRxiv |
| VGLL1 contributes to both the transcriptome and epigenome of the developing trophoblast compartment. |
2025 |
Proc Natl Acad Sci U S A |
| Visualizing PIEZO1 localization and activity in hiPSC-derived single cells and organoids with HaloTag technology. |
2025 |
Nat Commun |
| What a pain in the back: etiology, diagnosis and future treatment directions for discogenic low back pain. |
2025 |
Bone Res |
| Wnt/beta-catenin maintains epithelial IL-33 in the colonic stem and progenitor cell niche and drives its induction in colitis. |
2025 |
Mucosal Immunol |
| Xenophagocytosis blockade enhances interspecies chimerism. |
2025 |
bioRxiv |
| A CD38-directed, single-chain T-cell engager targets leukemia stem cells through IFN-gamma-induced CD38 expression. |
2024 |
Blood |
| A common cis-regulatory variant impacts normal-range and disease-associated human facial shape through regulation of PKDCC during chondrogenesis. |
2024 |
Elife |
| A facilitatory role of astrocytes in axonal regeneration after acute and chronic spinal cord injury. |
2024 |
Exp Neurol |
| A fibroblast-dependent TGF-beta1/sFRP2 noncanonical Wnt signaling axis promotes epithelial metaplasia in idiopathic pulmonary fibrosis. |
2024 |
J Clin Invest |
| A framework for N-of-1 trials of individualized gene-targeted therapies for genetic diseases. |
2024 |
Nat Commun |
| A lymphocyte chemoaffinity axis for lung, non-intestinal mucosae and CNS. |
2024 |
Nature |
| A maternal brain hormone that builds bone. |
2024 |
Nature |
| A novel high-titer, bifunctional lentiviral vector for autologous hematopoietic stem cell gene therapy of sickle cell disease. |
2024 |
Mol Ther Methods Clin Dev |
| A novel micropeptide, Slitharin, exerts cardioprotective effects in myocardial infarction. |
2024 |
Proteomics Clin Appl |
| A Panoramic View of Cell Population Dynamics in Mammalian Aging. |
2024 |
bioRxiv |
| A personalized medicine approach to optimize care for a pediatric cystic fibrosis patient with atypical clinical symptoms. |
2024 |
Pediatr Pulmonol |
| A scalable and cGMP-compatible autologous organotypic cell therapy for Dystrophic Epidermolysis Bullosa. |
2024 |
Nat Commun |
| A therapy for suppressing canonical and noncanonical SARS-CoV-2 viral entry and an intrinsic intrapulmonary inflammatory response. |
2024 |
Proc Natl Acad Sci U S A |
| Acid-degradable lipid nanoparticles enhance the delivery of mRNA. |
2024 |
Nat Nanotechnol |
| Activation of ductal progenitor-like cells from adult human pancreas requires extracellular matrix protein signaling. |
2024 |
iScience |
| Age-associated imbalance in immune cell regeneration varies across individuals and arises from a distinct subset of stem cells. |
2024 |
Cell Mol Immunol |
| AMPK Drives both Glycolytic and Oxidative Metabolism in Murine and Human T Cells During Graft-versus-host Disease. |
2024 |
Blood Adv |
| An age-progressive platelet differentiation path from hematopoietic stem cells causes exacerbated thrombosis. |
2024 |
Cell |
| An Endothelial Cell Is Not Simply an Endothelial Cell. |
2024 |
Stem Cells Dev |
| An experimental census of retrons for DNA production and genome editing. |
2024 |
bioRxiv |
| An improved method for generating human spinal cord neural stem cells. |
2024 |
Exp Neurol |
| Ancestral Diversity of Skin Reaches Single-Cell Resolution. |
2024 |
J Invest Dermatol |
| Antigen-Specific T Cell Receptor Discovery for Treating Progressive Multifocal Leukoencephalopathy. |
2024 |
bioRxiv |
| Antisense oligonucleotide therapy in an individual with KIF1A-associated neurological disorder. |
2024 |
Nat Med |
| Antiviral cellular therapy for enhancing T-cell reconstitution before or after hematopoietic stem cell transplantation (ACES): a two-arm, open label phase II interventional trial of pediatric patients with risk factor assessment. |
2024 |
Nat Commun |
| Atypical KCNQ1/Kv7 channel function in a neonatal diabetes patient: Hypersecretion preceded the failure of pancreatic beta-cells. |
2024 |
iScience |
| BCR::ABL1 kinase N-lobe mutants confer moderate to high degrees of resistance to asciminib. |
2024 |
Blood |
| Biological Pacemakers: Present and Future. |
2024 |
Circ Res |
