Publications by Grantees

CIRM funding supported the following publications. Click on the publication title for a brief summary of the research and for more information:

Title Year Journal
Chemically Defined Production of Tri-Lineage Human iPSC-Derived Cardiac Spheroids. 2023 Curr Protoc
Combination of Distinct Vascular Stem/Progenitor Cells for Neovascularization and Ischemic Rescue. 2023 Arterioscler Thromb Vasc Biol
Comparative analysis between single-cell RNA-seq and single-molecule RNA FISH indicates that the pyrimidine nucleobase idoxuridine (IdU) globally amplifies transcriptional noise. 2023 bioRxiv
Complex urban atmosphere alters alveolar stem cells niche properties and drives lung fibrosis. 2023 Am J Physiol Lung Cell Mol Physiol
Conductive electrospun polymer improves stem cell-derived cardiomyocyte function and maturation. 2023 Biomaterials
Context matters: hPSC-derived microglia thrive in a humanized brain environment in vivo. 2023 Cell Stem Cell
Coordination between ECM and cell-cell adhesion regulates the development of islet aggregation, architecture, and functional maturation. 2023 Elife
Craniofacial developmental biology in the single-cell era. 2023 Development
CryoET reveals organelle phenotypes in huntington disease patient iPSC-derived and mouse primary neurons. 2023 Nat Commun
Dermomyotome-derived endothelial cells migrate to the dorsal aorta to support hematopoietic stem cell emergence. 2023 Elife
Developing a human iPSC-derived three-dimensional myelin spheroid platform for modeling myelin diseases. 2023 iScience
Developing Hypoimmunogenic Human iPSC-Derived Oligodendrocyte Progenitor Cells as an Off-The-Shelf Cell Therapy for Myelin Disorders. 2023 Adv Sci (Weinh)
DNA Methylation Dynamics During Esophageal Epithelial Regeneration Following Repair with Acellular Silk Fibroin Grafts in Rat. 2023 Adv Biol (Weinh)
Efficient manufacturing and engraftment of CCR5 gene-edited HSPCs following busulfan conditioning in nonhuman primates. 2023 Mol Ther Methods Clin Dev
Endocytosis inhibitors block SARS-CoV-2 pseudoparticle infection of mink lung epithelium. 2023 Front Microbiol
Engineered multi-functional, pro-angiogenic collagen-based scaffolds loaded with endothelial cells promote large deep burn wound healing. 2023 Front Pharmacol
Engineering CpG island DNA methylation in pluripotent cells through synthetic CpG-free ssDNA insertion. 2023 Cell Rep Methods
Engineering Immunomodulatory Biomaterials to Drive Skin Wounds toward Regenerative Healing. 2023 Cold Spring Harb Perspect Biol
Enhanced peripheral nerve regeneration by mechano-electrical stimulation. 2023 NPJ Regen Med
Establishing a Disease-in-a-Dish Model to Study SARS-CoV-2 Infection During Prenatal Development. 2023 Curr Protoc
Establishing induced pluripotent stem cell lines from two dominant optic atrophy patients with distinct OPA1 mutations and clinical pathologies. 2023 Front Genet
Estradiol Induces Neutrophil Expansion to Promote TSC-Null Tumor Progression. 2023 Endocrinology
Evaluation of the Elements of Short Hairpin RNAs in Developing shRNA-Containing CAR T Cells. 2023 Cancers (Basel)
FGF18 promotes human lung branching morphogenesis through regulating mesenchymal progenitor cells. 2023 Am J Physiol Lung Cell Mol Physiol
Framework humanization optimizes potency of anti-CD72 nanobody CAR-T cells for B-cell malignancies. 2023 J Immunother Cancer
Future regenerative therapies for corneal disease. 2023 Curr Opin Ophthalmol
Genetic Deletion of the LINC00520 Homolog in Mouse Aggravates Angiotensin II-Induced Hypertension. 2023 Noncoding RNA
GMP-grade human neural progenitors delivered subretinally protect vision in rat model of retinal degeneration and survive in minipigs. 2023 J Transl Med
Graft conditioning with fluticasone propionate reduces graft-versus-host disease upon allogeneic hematopoietic cell transplantation in mice. 2023 EMBO Mol Med
Graft-versus-Host Disease Modulation by Innate T Cells. 2023 Int J Mol Sci
Graphene-based cardiac sensors and actuators. 2023 Front Bioeng Biotechnol
GRHL2 and AP2a coordinate early surface ectoderm lineage commitment during development. 2023 iScience
Hardwiring tissue-specific AAV transduction in mice through engineered receptor expression. 2023 Nat Methods
Hedgehog Signaling in Cortical Development. 2023 Cells
How and Why the Circadian Clock Regulates Proliferation of Adult Epithelial Stem Cells. 2023 Stem Cells
Human enteroids as a tool to study conventional and ultra-high dose rate radiation. 2023 Integr Biol (Camb)
Human iPSC-derived neural progenitor cells secreting GDNF provide protection in rodent models of ALS and retinal degeneration. 2023 Stem Cell Reports
Human Neural Progenitors Expressing GDNF Enhance Retinal Protection in a Rodent Model of Retinal Degeneration. 2023 Stem Cells Transl Med
Human pallial MGE-type GABAergic interneuron cell therapy for chronic focal epilepsy. 2023 Cell Stem Cell
Hydrogel degradation promotes angiogenic and regenerative potential of cell spheroids for wound healing. 2023 Mater Today Bio
Identification of SALL4 Expressing Islet-1+ Cardiovascular Progenitor Cell Clones. 2023 Int J Mol Sci
Implantation of engineered adipocytes that outcompete tumors for resources suppresses cancer progression. 2023 bioRxiv
In utero delivery of mRNA to the heart, diaphragm and muscle with lipid nanoparticles. 2023 Bioact Mater
In vitro formation and extended culture of highly metabolically active and contractile tissues. 2023 PLoS One
In vivo protein turnover rates in varying oxygen tensions nominate MYBBP1A as a mediator of the hyperoxia response. 2023 Sci Adv
Inactive S. aureus Cas9 downregulates alpha-synuclein and reduces mtDNA damage and oxidative stress levels in human stem cell model of Parkinson’s disease. 2023 Sci Rep
Inclusion of 4-1BB Costimulation Enhances Selectivity and Functionality of IL13Ralpha2-Targeted Chimeric Antigen Receptor T Cells. 2023 Cancer Res Commun
Inhibition of HSD17B13 protects against liver fibrosis by inhibition of pyrimidine catabolism in nonalcoholic steatohepatitis. 2023 Proc Natl Acad Sci U S A
Intervertebral disc human nucleus pulposus cells associated with back pain trigger neurite outgrowth in vitro and pain behaviors in rats. 2023 Sci Transl Med
Latent diffusion augmentation enhances deep learning analysis of neuro-morphology in limbal stem cell deficiency. 2023 Front Med (Lausanne)