Publications by Grantees

CIRM funding supported the following publications. Click on the publication title for a brief summary of the research and for more information:

Title Year Journal
Stereochemical Control of Splice Modulation in FD-895 Analogues. 2023 J Med Chem
Strength of CAR signaling determines T cell versus ILC differentiation from pluripotent stem cells. 2023 Cell Rep
Subfunctionalized expression drives evolutionary retention of ribosomal protein paralogs Rps27 and Rps27l in vertebrates. 2023 Elife
Sustained postconfluent culture of human mammary epithelial cells enriches for luminal and c-Kit+ subtypes. 2023 Breast Cancer Res
Systems-level analyses dissociate genetic regulators of reactive oxygen species and energy production. 2023 bioRxiv
T-allo10 Infusion after αβ depleted-HSCT in Children and Young Adults with Hematologic Malignancies: Improved Immune Reconstitution in the Absence of Severe GvHD 2023 Transplantation and Cellular Therapy
Targeted Proteomic Profiling Revealed Roles of Small GTPases during Osteogenic Differentiation. 2023 Anal Chem
Targeting the ADPKD methylome using nanoparticle-mediated combination therapy. 2023 APL Bioeng
Thalamocortical circuits in generalized epilepsy: Pathophysiologic mechanisms and therapeutic targets. 2023 Neurobiol Dis
The sinoatrial node extracellular matrix promotes pacemaker phenotype and protects automaticity in engineered heart tissues from cyclic strain. 2023 Cell Rep
Therapeutic blood-brain barrier modulation and stroke treatment by a bioengineered FZD(4)-selective WNT surrogate in mice. 2023 Nat Commun
Theta Frequency Electromagnetic Stimulation Enhances Functional Recovery After Stroke. 2023 Transl Stroke Res
Transcriptional reprogramming restores UBE3A brain-wide and rescues behavioral phenotypes in an Angelman syndrome mouse model. 2023 Mol Ther
Transcriptomic Effects on the Mouse Heart Following 30 Days on the International Space Station. 2023 Biomolecules
Transplanted human neural stem cells rescue phenotypes in zQ175 Huntington’s disease mice and innervate the striatum. 2023 Mol Ther
TRF2 rescues telomere attrition and prolongs cell survival in Duchenne muscular dystrophy cardiomyocytes derived from human iPSCs. 2023 Proc Natl Acad Sci U S A
Tumor inflammation-associated neurotoxicity. 2023 Nat Med
Understanding cell fate acquisition in stem-cell-derived pancreatic islets using single-cell multiome-inferred regulomes. 2023 Dev Cell
Understanding Fibroblast Heterogeneity in Form and Function. 2023 Biomedicines
Vascularized liver-on-a-chip model to investigate nicotine-induced dysfunction. 2023 Biomicrofluidics
Wnt activation as a potential therapeutic approach to treat partial limbal stem cell deficiency. 2023 Sci Rep
A conserved YAP/Notch/REST network controls the neuroendocrine cell fate in the lungs. 2022 Nat Commun
A randomized placebo-controlled phase 3 study of mesenchymal stem cells induced to secrete high levels of neurotrophic factors in amyotrophic lateral sclerosis. 2022 Muscle Nerve
A reference human induced pluripotent stem cell line for large-scale collaborative studies. 2022 Cell Stem Cell
A scalable organoid model of human autosomal dominant polycystic kidney disease for disease mechanism and drug discovery. 2022 Cell Stem Cell
Absence of microglia promotes diverse pathologies and early lethality in Alzheimer’s disease mice. 2022 Cell Rep
Adapting Physiology in Functional Human Islet Organogenesis. 2022 Front Cell Dev Biol
Adult Expression of Tbr2 Is Required for the Maintenance but Not Survival of Intrinsically Photosensitive Retinal Ganglion Cells. 2022 Front Cell Neurosci
Advancing preclinical models of psychiatric disorders with human brain organoid cultures. 2022 Mol Psychiatry
Altered adult neurogenesis and gliogenesis in patients with mesial temporal lobe epilepsy. 2022 Nat Neurosci
An Ex Vivo 3D Tumor Microenvironment-Mimicry Culture to Study TAM Modulation of Cancer Immunotherapy. 2022 Cells
An NKX-COUP-TFII morphogenetic code directs mucosal endothelial addressin expression. 2022 Nat Commun
Anti-GD2 synergizes with CD47 blockade to mediate tumor eradication. 2022 Nat Med
Antibody screening data of human midgestation liver cells with a focus on hematopoietic, liver sinusoidal endothelial, and hepatoblast cell-populations. 2022 BMC Res Notes
Autophagy inducer rapamycin treatment reduces IFN-I-mediated Inflammation and improves anti-HIV-1 T cell response in vivo. 2022 JCI Insight
Biallelic pathogenic variants in COX11 are associated with an infantile-onset mitochondrial encephalopathy. 2022 Hum Mutat
Biomarkers of in vivo limbal stem cell function. 2022 Ocul Surf
Brain organoids, consciousness, ethics and moral status. 2022 Semin Cell Dev Biol
c-JUN inhibits mTORC2 and glucose uptake to promote self-renewal and obesity. 2022 iScience
Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation. 2022 Cell
CDK12 is hyperactivated and a synthetic-lethal target in BRAF-mutated melanoma. 2022 Nat Commun
Cell Morphology as an In Vivo Parameter for the Diagnosis of Limbal Stem Cell Deficiency. 2022 Cornea
Cloud-controlled microscopy enables remote project-based biology education in underserved Latinx communities. 2022 Heliyon
Collateral Arteriogenesis Involves a Sympathetic Denervation That Is Associated With Abnormal alpha-Adrenergic Signaling and a Transient Loss of Vascular Tone. 2022 Front Cardiovasc Med
Comment on: Long-Term Outcome After Superficial Keratectomy of the Abnormal Epithelium for Partial Limbal Stem Cell Deficiency. 2022 Am J Ophthalmol
COVID-19 vaccination elicits an evolving, cross-reactive antibody response to epitopes conserved with endemic coronavirus spike proteins. 2022 Cell Rep
Cross-species comparisons reveal resistance of human skeletal stem cells to inhibition by non-steroidal anti-inflammatory drugs. 2022 Front Endocrinol (Lausanne)
Cytokeratin 13 Is a New Biomarker for the Diagnosis of Limbal Stem Cell Deficiency. 2022 Cornea
Decellularized Adipose Matrices Can Alleviate Radiation-Induced Skin Fibrosis. 2022 Adv Wound Care (New Rochelle)
Development of off-the-shelf hematopoietic stem cell-engineered invariant natural killer T cells for COVID-19 therapeutic intervention. 2022 Stem Cell Res Ther