Publications by Grantees

CIRM funding supported the following publications. Click on the publication title for a brief summary of the research and for more information:

Title Year Journal
Strength of CAR signaling determines T cell versus ILC differentiation from pluripotent stem cells. 2023 Cell Rep
Subfunctionalized expression drives evolutionary retention of ribosomal protein paralogs Rps27 and Rps27l in vertebrates. 2023 Elife
Sustained postconfluent culture of human mammary epithelial cells enriches for luminal and c-Kit+ subtypes. 2023 Breast Cancer Res
Systemic Delivery of Extracellular Vesicles Attenuates Atrial Fibrillation in Heart Failure With Preserved Ejection Fraction. 2023 JACC Clin Electrophysiol
Systems-level analyses dissociate genetic regulators of reactive oxygen species and energy production. 2023 bioRxiv
T-allo10 Infusion after αβ depleted-HSCT in Children and Young Adults with Hematologic Malignancies: Improved Immune Reconstitution in the Absence of Severe GvHD 2023 Transplantation and Cellular Therapy
Targeted Proteomic Profiling Revealed Roles of Small GTPases during Osteogenic Differentiation. 2023 Anal Chem
Targeting Endothelial HIF2alpha/ARNT Expression for Ischemic Heart Disease Therapy. 2023 Biology (Basel)
Targeting the ADPKD methylome using nanoparticle-mediated combination therapy. 2023 APL Bioeng
TDO2-augmented fibroblasts secrete EVs enriched in immunomodulatory Y-derived small RNA. 2023 J Extracell Biol
Tetracycline-Inducible and Reversible Stable Gene Expression in Human iPSC-Derived Neural Progenitors and in the Postnatal Mouse Brain. 2023 Curr Protoc
Thalamocortical circuits in generalized epilepsy: Pathophysiologic mechanisms and therapeutic targets. 2023 Neurobiol Dis
The breadth of the neutralizing antibody response to original SARS-CoV-2 infection is linked to the presence of Long COVID symptoms. 2023 J Med Virol
The hunt for novel AAV capsids with improved cardiac tropism. 2023 Mol Ther Methods Clin Dev
The sinoatrial node extracellular matrix promotes pacemaker phenotype and protects automaticity in engineered heart tissues from cyclic strain. 2023 Cell Rep
The tour-de-force for reducing cardiovascular disease risk in diabetic patients. 2023 Int J Cardiol
Therapeutic blood-brain barrier modulation and stroke treatment by a bioengineered FZD(4)-selective WNT surrogate in mice. 2023 Nat Commun
Theta Frequency Electromagnetic Stimulation Enhances Functional Recovery After Stroke. 2023 Transl Stroke Res
Transcriptional reprogramming restores UBE3A brain-wide and rescues behavioral phenotypes in an Angelman syndrome mouse model. 2023 Mol Ther
Transcriptomic Effects on the Mouse Heart Following 30 Days on the International Space Station. 2023 Biomolecules
Transplanted human neural stem cells rescue phenotypes in zQ175 Huntington’s disease mice and innervate the striatum. 2023 Mol Ther
TRF2 rescues telomere attrition and prolongs cell survival in Duchenne muscular dystrophy cardiomyocytes derived from human iPSCs. 2023 Proc Natl Acad Sci U S A
Tumor inflammation-associated neurotoxicity. 2023 Nat Med
Understanding cell fate acquisition in stem-cell-derived pancreatic islets using single-cell multiome-inferred regulomes. 2023 Dev Cell
Understanding Fibroblast Heterogeneity in Form and Function. 2023 Biomedicines
Vascularized liver-on-a-chip model to investigate nicotine-induced dysfunction. 2023 Biomicrofluidics
WIP1 is a novel specific target for growth hormone action. 2023 iScience
Wnt activation as a potential therapeutic approach to treat partial limbal stem cell deficiency. 2023 Sci Rep
A conserved YAP/Notch/REST network controls the neuroendocrine cell fate in the lungs. 2022 Nat Commun
A myocardial infarct border-zone-on-a-chip demonstrates distinct regulation of cardiac tissue function by an oxygen gradient. 2022 Sci Adv
A randomized placebo-controlled phase 3 study of mesenchymal stem cells induced to secrete high levels of neurotrophic factors in amyotrophic lateral sclerosis. 2022 Muscle Nerve
A reference human induced pluripotent stem cell line for large-scale collaborative studies. 2022 Cell Stem Cell
A scalable organoid model of human autosomal dominant polycystic kidney disease for disease mechanism and drug discovery. 2022 Cell Stem Cell
Absence of microglia promotes diverse pathologies and early lethality in Alzheimer’s disease mice. 2022 Cell Rep
Adapting Physiology in Functional Human Islet Organogenesis. 2022 Front Cell Dev Biol
Adult Expression of Tbr2 Is Required for the Maintenance but Not Survival of Intrinsically Photosensitive Retinal Ganglion Cells. 2022 Front Cell Neurosci
Advancing preclinical models of psychiatric disorders with human brain organoid cultures. 2022 Mol Psychiatry
Altered adult neurogenesis and gliogenesis in patients with mesial temporal lobe epilepsy. 2022 Nat Neurosci
An Ex Vivo 3D Tumor Microenvironment-Mimicry Culture to Study TAM Modulation of Cancer Immunotherapy. 2022 Cells
An NKX-COUP-TFII morphogenetic code directs mucosal endothelial addressin expression. 2022 Nat Commun
Anti-GD2 synergizes with CD47 blockade to mediate tumor eradication. 2022 Nat Med
Antibody screening data of human midgestation liver cells with a focus on hematopoietic, liver sinusoidal endothelial, and hepatoblast cell-populations. 2022 BMC Res Notes
Author Correction: Germline mutations in mitochondrial complex I reveal genetic and targetable vulnerability in IDH1-mutant acute myeloid leukaemia. 2022 Nat Commun
Autophagy inducer rapamycin treatment reduces IFN-I-mediated Inflammation and improves anti-HIV-1 T cell response in vivo. 2022 JCI Insight
Biallelic pathogenic variants in COX11 are associated with an infantile-onset mitochondrial encephalopathy. 2022 Hum Mutat
Biodistribution of unmodified cardiosphere-derived cell extracellular vesicles using single RNA tracing. 2022 J Extracell Vesicles
Biomarkers of in vivo limbal stem cell function. 2022 Ocul Surf
Brain organoids, consciousness, ethics and moral status. 2022 Semin Cell Dev Biol
c-JUN inhibits mTORC2 and glucose uptake to promote self-renewal and obesity. 2022 iScience
Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation. 2022 Cell