| A Method to Enrich Functional Human Paneth Cells in Induced Pluripotent Stem Cell-Derived Intestinal Organoids. |
2026 |
Cell Mol Gastroenterol Hepatol |
| A modular platform for automated organoid culture and longitudinal imaging. |
2026 |
Sci Rep |
| A Porcine Model of Intervertebral Disc Injury Recapitulates Human Discogenic Pain Via Notochordal Cell Loss and Pain-Inducing Nucleus Pulposus Cell Emergence. |
2026 |
JOR Spine |
| A region-delineated snRNA-seq atlas of mouse spinal cord across lifespan resolves the interaction of normative aging programs with SOD1-G93A ALS. |
2026 |
bioRxiv |
| A review exploring the translational perspective of artificial intelligence in drug discovery and formulation development. |
2026 |
Ann Pharm Fr |
| A single-cell multiomic analysis identifies molecular and gene-regulatory mechanisms dysregulated in developing Down syndrome neocortex. |
2026 |
Science |
| Aberrant Protein S-Nitrosylation Mimics the Effect of Rare Genetic Mutations in Neurodegenerative Diseases. |
2026 |
J Neurochem |
| Allogeneic CD70-Targeted Chimeric Antigen Receptor T-Cell Therapy for Advanced Renal Cell Carcinoma: Results From the Phase I TRAVERSE Trial. |
2026 |
J Clin Oncol |
| Antimicrobial proteins regulating neuroinflammation. |
2026 |
Ann Med |
| Biological pacemaker induced by focal cardiac transduction with AAV-TBX18. |
2026 |
Mol Ther |
| Brinzolamide microsponge-loaded in situ gel for sustained ocular delivery: design, characterization and in vivo evaluation. |
2026 |
Naunyn Schmiedebergs Arch Pharmacol |
| C1q-CD44 interactions regulate microglial phagocytosis, proliferation, and migration. |
2026 |
J Neuroinflammation |
| Cell-autonomous control of CAR signaling and receptor shedding via ADAM17-mediated proteolysis. |
2026 |
Cell |
| Clinical Outcomes of Lentiviral Vector Gene Therapy for Sickle Cell Disease. |
2026 |
Blood Adv |
| Comprehensive Ocular Characteristics in Cystinosis after Hematopoietic Stem-Cell Gene Therapy Over 24 Months. |
2026 |
Am J Ophthalmol |
| Concordant transcriptional and morphological remodeling revealed by in vivo Perturb-CLEAR. |
2026 |
bioRxiv |
| CRISPR/Cas strategies to enhance CAR T-cell function and persistence via metabolic reprogramming. |
2026 |
Trends Biotechnol |
| Cystinosin regulates Na(+)/H(+) exchanger 3 trafficking and function in kidney proximal tubular cells. |
2026 |
EMBO Rep |
| Development and validation of a potency assay matrix for optimized and consistent manufacture of clinical mesenchymal stem/stromal cells. |
2026 |
Front Immunol |
| Dissecting gene regulatory networks governing human cortical cell fate. |
2026 |
Nature |
| Dynamic Reorganization of Developmental to Adult Genome Topology Controls the Initiation and Stabilization of the Human Muscle Stem Cell State. |
2026 |
bioRxiv |
| Engineered mucus-tethering bispecific nanobodies enhance mucosal immunity against respiratory pathogens. |
2026 |
Nat Nanotechnol |
| Epigenetic and Transcriptional Programs Define Osteosarcoma Subtypes and Establish Targetable Vulnerabilities. |
2026 |
Cancer Discov |
| Feasibility and safety of cellular therapy for in-utero repair of myelomeningocele (CuRe Trial): a first-in-human, phase 1, single-arm study. |
2026 |
Lancet |
| Functional validation of the novel KIF5A p.R17Q VUS reveals defective axonal transport in iPSC-motoneurons from a SPG10 patient. |
2026 |
Front Genet |
| Genome-scale functional mapping of the mammalian whole brain with in vivo Perturb-seq. |
2026 |
bioRxiv |
| Hematopoietic Stem-Cell Gene Therapy for Cystinosis. |
2026 |
N Engl J Med |
| Human cardiac organoids for disease modeling and drug discovery. |
2026 |
Trends Mol Med |
| In vivo multiomic Perturb-seq with enhanced nuclear gRNA capture. |
2026 |
bioRxiv |
| Injectable Thermoresponsive Microgels Encapsulate and Precondition Nucleus Pulposus Cells for Intervertebral Disc Regeneration. |
2026 |
ACS Appl Bio Mater |
| Integrin Alpha 4 Inhibition Prolongs the Survival of NSG Mice Engrafted with CD19-Negative Post-CART19 Relapsed B-ALL. |
2026 |
Exp Hematol |
| Lesion-remote astrocytes govern microglia-mediated white matter repair. |
2026 |
Nature |
| Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site-Specific Integration of CFTR and Mutation-Agnostic Disease Rescue |
2026 |
Advanced Functional Materials |
| Mapping the dialogue: Decoding alveolar stem-niche interactions. |
2026 |
Proc Natl Acad Sci U S A |
| Neural stem cell delivery of oncolytic CRAd-S-pk7 immunotherapy for stage 3 ovarian cancer: Dose-regimen studies. |
2026 |
Mol Ther Oncol |
| On the interpretation of astrocytic calcium signalling with graphene oxide electrodes. |
2026 |
Nat Nanotechnol |
| Oxidative stress-regulatory role of miR-10b-5p in the diabetic human cornea revealed through integrated multi-omics analysis. |
2026 |
Diabetologia |
| Probing neuropsychiatric disorders through in vivo CRISPR screening. |
2026 |
Curr Opin Genet Dev |
| Protocol for inducing dorsal spinal sensory interneurons from mouse embryonic stem cell-derived neuromesodermal progenitors. |
2026 |
STAR Protoc |
| RABEP1 regulates neutrophil migration via endosomal recycling and actin polymerization. |
2026 |
J Leukoc Biol |
| Reconstructing human corticogenesis: Insights from cerebral organoids into neurodevelopment and disease modeling. |
2026 |
Dev Cell |
| Redirection of sphingolipid metabolism drives cytoskeletal defects in SPLIS and reveals ROCK inhibition as therapy. |
2026 |
J Clin Invest |
| Restoration of the immune system with base editing and non-genotoxic conditioning in a Rag2 point-mutant mouse model. |
2026 |
Mol Ther |
| Single-Cell Analysis Reveals Peripheral Helper T Cells in Rheumatoid Arthritis-Related Interstitial Lung Disease. |
2026 |
Arthritis Rheumatol |
| Single-Cell Proteomics Reveals Novel Cell Phenotypes in Marfan Mouse Aneurysm. |
2026 |
Mol Cell Proteomics |
| Single-cell transcriptomics-informed induced pluripotent stem cells differentiation to tenogenic lineage. |
2026 |
Elife |
| Surviving the Nucleus Pulposus Desert: Next-Generation Strategies for Intervertebral Disc Cell Therapy. |
2026 |
JOR Spine |
| Syndecan-1 Promotes Alveolar Type 2 Epithelial Cell Senescence during Lung Fibrosis. |
2026 |
bioRxiv |
| Virus-like particles based on plant viruses and bacteriophages: emerging strategies for the delivery of nucleic acid therapeutics. |
2026 |
Chem Sci |
| Wnt signaling as a regulator of memory T cells: implications for CAR-T cell therapy. |
2026 |
Front Immunol |
