| Probing DNA damage in Rett syndrome neurons uncovers a role for MECP2 regulation of PARP1. |
2025 |
Stem Cell Reports |
| Proof of concept for brain organoid-on-a-chip to create multiple domains in forebrain organoids. |
2025 |
RSC Adv |
| Proteasome inhibition enhances oncolytic reovirus therapy in multiple myeloma independently of its direct cytotoxic effects. |
2025 |
J Hematol Oncol |
| Proteome-wide profiling of S-nitrosylated proteins using the SNOTRAP probe and mass spectrometry-based detection. |
2025 |
Nat Protoc |
| Protocol for the isolation and characterization of mouse alveolar bone marrow hematopoietic stem cells. |
2025 |
STAR Protoc |
| Protocol for vibratome sectioning, immunofluorescence, and S-phase labeling of inner ear organoids. |
2025 |
STAR Protoc |
| Protocol to study ductal progenitor-like cells from the adult human pancreas using 3D suspension and methylcellulose-based culture systems. |
2025 |
STAR Protoc |
| PTPN2 Regulates Iron Handling Protein Expression in Inflammatory Bowel Disease Patients and Prevents Iron Deficiency in Mice. |
2025 |
Int J Mol Sci |
| Rapamycin enhances CAR-T control of HIV replication and reservoir elimination in vivo. |
2025 |
J Clin Invest |
| Reversible proliferative arrest induced by rapid depletion of RNase MRP. |
2025 |
Nat Commun |
| Safe immunosuppression-resistant pan-cancer immunotherapeutics by velcro-like density-dependent targeting of tumor-associated carbohydrate antigens. |
2025 |
Cell |
| Size and Structural Control of Mechanoluminescent ZnS:Mn(2+) Nanocrystals for Optogenetic Neuromodulation. |
2025 |
ACS Nano |
| Spatial and Single-Cell Transcriptomics Reveal Keratinocytes as Key Players in Vulvar Lichen Sclerosus Pathogenesis. |
2025 |
J Invest Dermatol |
| Spatially patterned kidney assembloids recapitulate progenitor self-assembly and enable high-fidelity in vivo disease modeling. |
2025 |
Cell Stem Cell |
| Spinal Cord Injury in Real Time: Intra-Operative Ultrasound for Acute Phase Examination in Non-Human Primates. |
2025 |
Brain Sci |
| Structural and functional analysis of cancer-associated missense variants in the retinoblastoma protein pocket domain. |
2025 |
J Biol Chem |
| Suppressing APOE4-induced neural pathologies by targeting the VHL-HIF axis. |
2025 |
Proc Natl Acad Sci U S A |
| Systemic deficits in lipid homeostasis promote aging-associated impairments in B cell progenitor development. |
2025 |
Geroscience |
| The HIV-1 nuclear export complex reveals the role of RNA in CRM1 cargo recognition. |
2025 |
Mol Cell |
| The Proteostasis Network is a Therapeutic Target in Acute Myeloid Leukemia. |
2025 |
Blood |
| The PTPN2 rs1893217 IBD risk allele increases susceptibility to AIEC invasion by a JAK-STAT-CEACAM6 axis. |
2025 |
Gut Microbes |
| The single-molecule accessibility landscape of newly replicated mammalian chromatin. |
2025 |
Cell |
| The UCSC Genome Browser database: 2025 update. |
2025 |
Nucleic Acids Res |
| Therapeutic genetic restoration through allogeneic brain microglia replacement. |
2025 |
Nature |
| Understanding human embryogenesis by building programmable stem cell-based models. |
2025 |
Trends Cell Biol |
| Upregulated FoxO1 promotes arrhythmogenesis in mice with heart failure and preserved ejection fraction. |
2025 |
Nat Commun |
| VGLL1 contributes to both the transcriptome and epigenome of the developing trophoblast compartment. |
2025 |
bioRxiv |
| Visualizing PIEZO1 localization and activity in hiPSC-derived single cells and organoids with HaloTag technology. |
2025 |
Nat Commun |
| Wnt/beta-catenin maintains epithelial IL-33 in the colonic stem and progenitor cell niche and drives its induction in colitis. |
2025 |
Mucosal Immunol |
| Xenophagocytosis blockade enhances interspecies chimerism. |
2025 |
bioRxiv |
| A CD38-directed, single-chain T-cell engager targets leukemia stem cells through IFN-gamma-induced CD38 expression. |
2024 |
Blood |
| A common cis-regulatory variant impacts normal-range and disease-associated human facial shape through regulation of PKDCC during chondrogenesis. |
2024 |
Elife |
| A facilitatory role of astrocytes in axonal regeneration after acute and chronic spinal cord injury. |
2024 |
Exp Neurol |
| A fibroblast-dependent TGF-beta1/sFRP2 noncanonical Wnt signaling axis promotes epithelial metaplasia in idiopathic pulmonary fibrosis. |
2024 |
J Clin Invest |
| A framework for N-of-1 trials of individualized gene-targeted therapies for genetic diseases. |
2024 |
Nat Commun |
| A lymphocyte chemoaffinity axis for lung, non-intestinal mucosae and CNS. |
2024 |
Nature |
| A maternal brain hormone that builds bone. |
2024 |
Nature |
| A novel high-titer, bifunctional lentiviral vector for autologous hematopoietic stem cell gene therapy of sickle cell disease. |
2024 |
Mol Ther Methods Clin Dev |
| A Panoramic View of Cell Population Dynamics in Mammalian Aging. |
2024 |
bioRxiv |
| A scalable and cGMP-compatible autologous organotypic cell therapy for Dystrophic Epidermolysis Bullosa. |
2024 |
Nat Commun |
| A therapy for suppressing canonical and noncanonical SARS-CoV-2 viral entry and an intrinsic intrapulmonary inflammatory response. |
2024 |
Proc Natl Acad Sci U S A |
| Acid-degradable lipid nanoparticles enhance the delivery of mRNA. |
2024 |
Nat Nanotechnol |
| Activation of ductal progenitor-like cells from adult human pancreas requires extracellular matrix protein signaling. |
2024 |
iScience |
| Age-associated imbalance in immune cell regeneration varies across individuals and arises from a distinct subset of stem cells. |
2024 |
Cell Mol Immunol |
| AMPK Drives both Glycolytic and Oxidative Metabolism in Murine and Human T Cells During Graft-versus-host Disease. |
2024 |
Blood Adv |
| An age-progressive platelet differentiation path from hematopoietic stem cells causes exacerbated thrombosis. |
2024 |
Cell |
| An Endothelial Cell Is Not Simply an Endothelial Cell. |
2024 |
Stem Cells Dev |
| An experimental census of retrons for DNA production and genome editing. |
2024 |
bioRxiv |
| An improved method for generating human spinal cord neural stem cells. |
2024 |
Exp Neurol |
| Ancestral Diversity of Skin Reaches Single-Cell Resolution. |
2024 |
J Invest Dermatol |
