Active Awards Portfolio Dashboard

It takes a lot of effort to develop a promising stem cell research idea into an effective treatment that can help patients. CIRM funds a pipeline of projects spanning discovery, translation and clinical stage research. Check out our portfolio of active research awards in our interactive dashboard below. For a detailed list of CIRM-funded clinical trials, visit our Clinical Trials Dashboard.

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Disease Cell Type Therapeutic or Technology Institution Stage Project Objective Details
Immune Disease,
Severe Combined Immunodeficiency, X-linked (X-SCID)
Adult Stem Cell Antibody Stanford
Clinical Trial, Phase 1 or Phase 1/2
Melanoma,
Skin cancer
Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Clinical Trial, Phase 1 or Phase 1/2
Osteonecrosis Adult Stem Cell Small molecule therapy UC Davis
Clinical Trial, Phase 1 or Phase 1/2
Heart Disease Embryonic Stem Cell Donor cell therapy Stanford
IND
Intestinal Disease Adult Stem Cell Personalized cell therapy CHLA
Development Candidate, Proof of Concept
Blood Disorders Embryonic Stem Cell Donor cell therapy UCSF
Research Insights
Sickle Cell Disease Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Clinical Trial, Phase 1 or Phase 1/2
Age-related macular degeneration Embryonic Stem Cell Donor cell therapy USC
Clinical Trial, Phase 1 or Phase 1/2
Blood Disorders iPS Cell Model system development Stanford
Research Insights, Tool/Resources/Bottleneck
Amyotrophic Lateral Sclerosis,
Spinal Cord Injury
Embryonic Stem Cell,
iPS Cell
Cell imaging & tracking UCSD
Research Insights
Spinal Cord Injury Embryonic Stem Cell Donor cell therapy Asterias
Clinical Trial, Phase 1 or Phase 1/2
HIV/AIDS Adult Stem Cell Gene-modified, personalized cell therapy COH
Clinical Trial, Phase 1 or Phase 1/2
Other Embryonic Stem Cell Cell imaging & tracking UC Berkeley
Tool/Resources/Bottleneck
Heart Disease,
Neurological Disorders
Embryonic Stem Cell,
iPS Cell
Tissue engineering Gladstone
Proof of Concept, Research Insights
Liver Disease iPS Cell Cell processing & handling USC
Tool/Resources/Bottleneck
Blood Disorders Embryonic Stem Cell Specific Cell Type Derivation UCLA
Tool/Resources/Bottleneck
Bone or Cartilage Disease Adult Stem Cell Tissue engineering Stanford
Proof of Concept, Research Insights
HIV-related Lymphoma,
HIV/AIDS
Adult Stem Cell Gene-modified, personalized cell therapy UC Davis
Clinical Trial, Phase 1 or Phase 1/2
Immune Disease,
X-linked Chronic Granulomatous Disease
Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Clinical Trial, Phase 1 or Phase 1/2
Blood Disorders Adult Stem Cell Exploring stem cell mechanisms UCLA
Development Candidate, Proof of Concept, Research Insights
Intestinal Disease,
Neurological Disorders
iPS Cell Donor cell therapy CHLA
Pre-IND/IDE or Equivalent
Metabolic Disorders,
Neurological Disorders
Adult Stem Cell Gene-modified, personalized cell therapy UC Davis
Pre-IND/IDE or Equivalent
Brain Cancer Cancer Stem Cell Vaccine Stanford
Pre-IND/IDE or Equivalent
Canavan Disease iPS Cell Gene-modified, personalized cell therapy COH
Pre-IND/IDE or Equivalent
Multiple Myeloma Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Pre-IND/IDE or Equivalent
Vision Loss iPS Cell Cell processing & handling UCSD
Tool/Resources/Bottleneck
Cystinosis Adult Stem Cell Gene-modified, personalized cell therapy UCSD
IND
Kidney Failure Adult Stem Cell Biologic Humacyte
Clinical Trial, Phase 3
Bone or Cartilage Disease Embryonic Stem Cell Donor cell therapy USC
Pre-IND/IDE or Equivalent
Sickle Cell Disease Adult Stem Cell Gene-modified, personalized cell therapy CHORI
Pre-IND/IDE or Equivalent
Pulmonary Hypertension,
Vascular Disease
Adult Stem Cell Donor cell therapy Cedars-Sinai
Clinical Trial, Phase 1 or Phase 1/2
Colon Cancer Cancer Stem Cell Antibody Forty Seven
Clinical Trial, Phase 1 or Phase 1/2
Blood Disorders,
Immune Disease
Adult Stem Cell Gene-modified, personalized cell therapy Stanford
Development Candidate
Liver Disease Adult Stem Cell Donor cell therapy Stanford
Development Candidate
Huntington's Disease Embryonic Stem Cell Gene-modified, donor cell therapy UC Irvine
Development Candidate, Proof of Concept
Blood Cancer,
Ovarian Cancer
Embryonic Stem Cell,
iPS Cell
Donor cell therapy UCSD
Development Candidate
Diabetes Embryonic Stem Cell Donor cell therapy UCSF
Development Candidate, Proof of Concept
Cystic Fibrosis Adult Stem Cell Gene-modified, personalized cell therapy Stanford
Development Candidate
Neurological Disorders,
Zika virus
iPS Cell Small molecule therapy UCSD
Development Candidate
Corneal Damage Adult Stem Cell Personalized cell therapy UCLA
IND
Retinitis Pigmentosa Adult Stem Cell Donor cell therapy jCyte
Clinical Trial, Phase 2
Kidney Failure Adult Stem Cell Donor cell therapy Stanford
Clinical Trial, Phase 1 or Phase 1/2
Vascular Disease Adult Stem Cell Biologic UCSD
Pre-IND/IDE or Equivalent
Heart Disease iPS Cell Assay development Stanford
Tool/Resources/Bottleneck
Type 1 diabetes Adult Stem Cell Personalized cell therapy Caladrius Biosciences
Clinical Trial, Phase 2
Amyotrophic Lateral Sclerosis Adult Stem Cell Gene-modified, donor cell therapy Cedars-Sinai
Clinical Trial, Phase 1 or Phase 1/2
Immune Disease,
Severe Combined Immunodeficiency, X-linked (X-SCID)
Adult Stem Cell Gene-modified, personalized cell therapy St. Jude
Clinical Trial, Phase 1 or Phase 1/2
Skeletal/Smooth Muscle disorders Adult Stem Cell Protein/peptide therapy Stanford
Research Insights
B cell cancers,
Leukemia
Cancer Stem Cell Antibody COH
Development Candidate, Proof of Concept
Liver Disease Directly Reprogrammed Cell Gene modification UCSF
Development Candidate

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