Active Awards Portfolio Dashboard

It takes a lot of effort to develop a promising stem cell research idea into an effective treatment that can help patients. CIRM funds a pipeline of projects spanning discovery, translation and clinical stage research. Check out our portfolio of active research awards in our interactive dashboard below. For a detailed list of CIRM-funded clinical trials, visit our Clinical Trials Dashboard.

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Disease Cell Type Therapeutic or Technology Institution Stage Project Objective Details
Immune Disease,
Severe Combined Immunodeficiency, X-linked (X-SCID)
Adult Stem Cell Antibody Stanford
Clinical Trial, Phase 1 or Phase 1/2
Osteonecrosis Adult Stem Cell Small molecule therapy UC Davis
Clinical Trial, Phase 1 or Phase 1/2
Intestinal Disease Adult Stem Cell Personalized cell therapy CHLA
Development Candidate, Proof of Concept
Sickle Cell Disease Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Clinical Trial, Phase 1 or Phase 1/2
Blood Disorders iPS Cell Model system development Stanford
Research Insights, Tool/Resources/Bottleneck
Amyotrophic Lateral Sclerosis,
Spinal Cord Injury
Embryonic Stem Cell,
iPS Cell
Cell imaging & tracking UCSD
Research Insights
Spinal Cord Injury Embryonic Stem Cell Donor cell therapy Lineage Cell
Clinical Trial, Phase 1 or Phase 1/2
HIV/AIDS Adult Stem Cell Gene-modified, personalized cell therapy COH
Clinical Trial, Phase 1 or Phase 1/2
Other Embryonic Stem Cell Cell imaging & tracking UC Berkeley
Tool/Resources/Bottleneck
Heart Disease,
Neurological Disorders
Embryonic Stem Cell,
iPS Cell
Tissue engineering Gladstone
Proof of Concept, Research Insights
HIV-related Lymphoma,
HIV/AIDS
Adult Stem Cell Gene-modified, personalized cell therapy UC Davis
Clinical Trial, Phase 1 or Phase 1/2
Immune Disease,
X-linked Chronic Granulomatous Disease
Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Clinical Trial, Phase 1 or Phase 1/2
Blood Disorders,
Leukemia
Adult Stem Cell Exploring stem cell mechanisms UCLA
Development Candidate, Proof of Concept, Research Insights
Intestinal Disease,
Neurological Disorders
iPS Cell Donor cell therapy CHLA
Pre-IND/IDE or Equivalent
Canavan Disease iPS Cell Gene-modified, personalized cell therapy COH
Pre-IND/IDE or Equivalent
Multiple Myeloma Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Pre-IND/IDE or Equivalent
Kidney Failure Adult Stem Cell Biologic Humacyte
Clinical Trial, Phase 3
Bone or Cartilage Disease Embryonic Stem Cell Donor cell therapy USC
Pre-IND/IDE or Equivalent
Sickle Cell Disease Adult Stem Cell Gene-modified, personalized cell therapy CHORI
Pre-IND/IDE or Equivalent
Pulmonary Hypertension,
Vascular Disease
Adult Stem Cell Donor cell therapy Cedars-Sinai
Clinical Trial, Phase 1 or Phase 1/2
Colon Cancer Cancer Stem Cell Antibody Forty Seven
Clinical Trial, Phase 1 or Phase 1/2
Liver Disease Adult Stem Cell Donor cell therapy Stanford
Development Candidate
Corneal Damage Adult Stem Cell Personalized cell therapy UCLA
IND
Retinitis Pigmentosa Other Donor cell therapy jCyte
Clinical Trial, Phase 2
Kidney Failure Adult Stem Cell Donor cell therapy Stanford
Clinical Trial, Phase 1 or Phase 1/2
Vascular Disease Adult Stem Cell Biologic UCSD
Pre-IND/IDE or Equivalent
Type 1 diabetes Adult Stem Cell Personalized cell therapy Caladrius Biosciences
Clinical Trial, Phase 2
Amyotrophic Lateral Sclerosis Adult Stem Cell Gene-modified, donor cell therapy Cedars-Sinai
Clinical Trial, Phase 1 or Phase 1/2
Immune Disease,
Severe Combined Immunodeficiency, X-linked (X-SCID)
Adult Stem Cell Gene-modified, personalized cell therapy St. Jude
Clinical Trial, Phase 1 or Phase 1/2
Skeletal/Smooth Muscle disorders Adult Stem Cell Protein/peptide therapy Stanford
Research Insights
B cell cancers,
Leukemia
Cancer Stem Cell Antibody COH
Development Candidate, Proof of Concept
Liver Disease Directly Reprogrammed Cell Gene modification UCSF
Development Candidate
Heart Disease iPS Cell Model system development UC Berkeley
Proof of Concept
Colon Cancer Cancer Stem Cell Small molecule therapy COH
Development Candidate, Proof of Concept
Heart Disease iPS Cell Donor cell therapy Stanford
Development Candidate, Proof of Concept
Heart Disease iPS Cell Personalized cell therapy UC Davis
Proof of Concept
Hyper IgM Syndrome Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Development Candidate, Proof of Concept
Other Embryonic Stem Cell,
iPS Cell
Cell processing & handling X-Therma
Proof of Concept, Tool/Resources/Bottleneck
Neurological Disorders,
Zika virus
Adult Stem Cell,
iPS Cell
Vaccine UCLA
Development Candidate
Traumatic Brain Injury Embryonic Stem Cell Donor cell therapy UC Irvine
Development Candidate
Stroke Embryonic Stem Cell Donor cell therapy Stanford
IND
Leukemia, Acute Myeloid (AML) Cancer Stem Cell Antibody Cellerant Therapeutics
IND
Stroke Adult Stem Cell Gene-modified, donor cell therapy SanBio, Inc.
Clinical Trial, Phase 2
Alpha Thalassemia Major Adult Stem Cell Donor cell therapy UCSF
Clinical Trial, Phase 1 or Phase 1/2
Cancer Cancer Stem Cell Gene-modified, personalized cell therapy UCSD
Pre-IND/IDE or Equivalent
Amyotrophic Lateral Sclerosis Adult Stem Cell Personalized cell therapy BrainStorm
Clinical Trial, Phase 3
Blood Cancer Adult Stem Cell Gene-modified, donor cell therapy Angiocrine
Clinical Trial, Phase 1 or Phase 1/2
B cell cancers,
Leukemia
Cancer Stem Cell Antibody UCSD
Clinical Trial, Phase 1 or Phase 1/2
Sickle Cell Disease Adult Stem Cell Gene-modified, personalized cell therapy Stanford
IND
Type 1 diabetes Embryonic Stem Cell Donor cell therapy ViaCyte
Clinical Trial, Phase 1 or Phase 1/2

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