Active Awards Portfolio Dashboard

It takes a lot of effort to develop a promising stem cell research idea into an effective treatment that can help patients. CIRM funds a pipeline of projects spanning discovery, translation and clinical stage research. Check out our portfolio of active research awards in our interactive dashboard below. For a detailed list of CIRM-funded clinical trials, visit our Clinical Trials Dashboard.

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Disease Cell Type Therapeutic or Technology Institution Stage Project Objective Details
Osteonecrosis Adult Stem Cell Small molecule therapy UC Davis
Clinical Trial, Phase 1 or Phase 1/2
Sickle Cell Disease Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Clinical Trial, Phase 1 or Phase 1/2
Amyotrophic Lateral Sclerosis,
Spinal Cord Injury
Embryonic Stem Cell,
iPS Cell
Cell imaging & tracking UCSD
Research Insights
HIV/AIDS Adult Stem Cell Gene-modified, personalized cell therapy COH
Clinical Trial, Phase 1 or Phase 1/2
HIV-related Lymphoma,
HIV/AIDS
Adult Stem Cell Gene-modified, personalized cell therapy UC Davis
Clinical Trial, Phase 1 or Phase 1/2
Immune Disease,
X-linked Chronic Granulomatous Disease
Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Clinical Trial, Phase 1 or Phase 1/2
Intestinal Disease,
Neurological Disorders
iPS Cell Donor cell therapy CHLA
Pre-IND/IDE or Equivalent
Canavan Disease iPS Cell Gene-modified, personalized cell therapy COH
Pre-IND/IDE or Equivalent
Pulmonary Hypertension,
Vascular Disease
Adult Stem Cell Donor cell therapy Cedars-Sinai
Clinical Trial, Phase 1 or Phase 1/2
Retinitis Pigmentosa Other Donor cell therapy jCyte
Clinical Trial, Phase 2
Kidney Failure Adult Stem Cell Donor cell therapy Stanford
Clinical Trial, Phase 1 or Phase 1/2
Vascular Disease Adult Stem Cell Biologic UCSD
Pre-IND/IDE or Equivalent
Amyotrophic Lateral Sclerosis Adult Stem Cell Gene-modified, donor cell therapy Cedars-Sinai
Clinical Trial, Phase 1 or Phase 1/2
Immune Disease,
Severe Combined Immunodeficiency, X-linked (X-SCID)
Adult Stem Cell Gene-modified, personalized cell therapy St. Jude
Clinical Trial, Phase 1 or Phase 1/2
Alpha Thalassemia Major Adult Stem Cell Donor cell therapy UCSF
Clinical Trial, Phase 1 or Phase 1/2
Leukemia Cancer Stem Cell Gene-modified, personalized cell therapy UCSD
Pre-IND/IDE or Equivalent
Amyotrophic Lateral Sclerosis Adult Stem Cell Personalized cell therapy BrainStorm
Clinical Trial, Phase 3
Blood Cancer Adult Stem Cell Gene-modified, donor cell therapy Angiocrine
Clinical Trial, Phase 1 or Phase 1/2
B cell cancers,
Leukemia
Cancer Stem Cell Antibody UCSD
Clinical Trial, Phase 1 or Phase 1/2
Type 1 diabetes Embryonic Stem Cell Donor cell therapy ViaCyte
Clinical Trial, Phase 1 or Phase 1/2
Brain Cancer Adult Stem Cell Gene-modified, personalized cell therapy COH
Clinical Trial, Phase 1 or Phase 1/2
Blood Cancer,
Bone Marrow Transplant and Viral Infection
Adult Stem Cell Donor cell therapy CHLA
Clinical Trial, Phase 1 or Phase 1/2
Multiple Myeloma Adult Stem Cell Gene-modified, personalized cell therapy Poseida Therapeutics
Clinical Trial, Phase 1 or Phase 1/2
Epidermolysis Bullosa iPS Cell Gene-modified, personalized cell therapy Stanford
Pre-IND/IDE or Equivalent
Leukemia, Acute Myeloid (AML) Cancer Stem Cell Small molecule therapy UCSD
Pre-IND/IDE or Equivalent
Leukemia, Acute Myeloid (AML) Embryonic Stem Cell Donor cell therapy UCSD
Pre-IND/IDE or Equivalent
Hemophilia A Adult Stem Cell Gene modification COH
Development Candidate, Proof of Concept
Kidney Failure Adult Stem Cell Donor cell therapy Medeor Therapeutics
Clinical Trial, Phase 3
Sickle Cell Disease Adult Stem Cell Donor cell therapy COH
Clinical Trial, Phase 1 or Phase 1/2
Severe Combined Immunodeficiency, Artemis deficient (ART-SCID) Adult Stem Cell Gene-modified, personalized cell therapy UCSF
Clinical Trial, Phase 1 or Phase 1/2
B cell cancers,
Leukemia
Adult Stem Cell Gene-modified, personalized cell therapy Stanford
Clinical Trial, Phase 1 or Phase 1/2
Beta Thalassemia Adult Stem Cell Gene-modified, personalized cell therapy Sangamo
Clinical Trial, Phase 1 or Phase 1/2
Immune Disease,
Severe Combined Immunodeficiency, Adenosine deaminase-deficient (ADA-SCID)
Adult Stem Cell Gene-modified, personalized cell therapy Orchard Therapeutics
Clinical Trial, Phase 2
Lung Cancer Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Clinical Trial, Phase 1 or Phase 1/2
Bladder or Urinary Tract Disorder,
Incontinence
iPS Cell Personalized cell therapy Stanford
Pre-IND/IDE or Equivalent
Retinitis Pigmentosa Embryonic Stem Cell Donor cell therapy UC Irvine
Pre-IND/IDE or Equivalent
Parkinson's Disease Adult Stem Cell Gene-modified, donor cell therapy UCSF
IND
Brain Cancer Adult Stem Cell Gene-modified, personalized cell therapy COH
IND
Brain Cancer Adult Stem Cell Gene-modified, personalized cell therapy UCSF
Development Candidate, Proof of Concept
Ovarian Cancer Adult Stem Cell Gene-modified, personalized cell therapy COH
Development Candidate, Proof of Concept
Thymic Disorder, 22q11 Deletion/DiGeorge Embryonic Stem Cell,
iPS Cell
Donor cell therapy Stanford
Development Candidate, Proof of Concept
Heart Disease,
Danon Disease
Adult Stem Cell Gene-modified, personalized cell therapy UCSD
Development Candidate, Proof of Concept
Dementia iPS Cell Donor cell therapy Gladstone
Development Candidate, Proof of Concept
Vision Loss iPS Cell Small molecule therapy UCSD
Development Candidate, Proof of Concept
Liver Disease iPS Cell Gene-modified, donor cell therapy CHLA
Development Candidate, Proof of Concept
Autism iPS Cell Small molecule therapy Scripps
Development Candidate, Proof of Concept
Hearing Loss Adult Stem Cell Protein/peptide therapy Stanford
Development Candidate, Proof of Concept
HIV/AIDS Personalized cell therapy COH
IND
Leukemia, Acute Myeloid (AML) Cancer Stem Cell Gene-modified, personalized cell therapy UCSF
Pre-IND/IDE or Equivalent
Age-related macular degeneration iPS Cell Personalized cell therapy UCLA
Pre-IND/IDE or Equivalent

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