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Institution Researcher name Grant Type Grant Title Award Value
Minutia, Inc. Katy Digovich Quest – Discovery Stage Research Projects Bioengineering human stem cell-derived beta cell organoids to monitor cell health in real time and improve therapeutic outcomes in patients $1,198,550
Nanotools Bioscience Dr. Alex Savtchenko PhD Quest – Discovery Stage Research Projects Enabling non-genetic activity-driven maturation of iPSC-derived neurons $675,000
University of California, Los Angeles Dr. Xian-Jie Yang Quest – Discovery Stage Research Projects Developing gene therapy for dominant optic atrophy using human pluripotent stem cell-derived retinal organoid disease models $1,345,691
University of California, San Diego Dr. Joseph G. Gleeson Quest – Discovery Stage Research Projects Novel antisense therapy to treat genetic forms of neurodevelopmental disease. $1,180,654
Scripps Research Institute Stuart A Lipton Quest – Discovery Stage Research Projects Drug Development of Inhibitors of Inflammation Using Human iPSC-Derived Microglia (hiMG) $1,658,123
University of California, Los Angeles Dr Dinesh S Rao Quest – Discovery Stage Research Projects Novel methods to eliminate cancer stem cells $1,384,347
University of California, San Diego Dr. Michael Karin Quest – Discovery Stage Research Projects Targeting pancreatic cancer stem cells with DDR1 antibodies. $1,425,600
Cedars-Sinai Medical Center Dr. Robert Barrett Quest – Discovery Stage Research Projects A new precision medicine based iPSC-derived model to study personalized intestinal fibrosis treatments in pediatric patients with Crohn’s disease $776,340
Scripps Research Institute Dr Michael J Bollong Quest – Discovery Stage Research Projects Therapeutics to overcome the differentiation roadblock in Myelodysplastic Syndrome (MDS) $1,244,160
University of California, Davis Dr. Kyle D Fink PhD Quest – Discovery Stage Research Projects AAV-dCas9 Epigenetic Editing for CDKL5 Deficiency Disorder $1,429,378
University of California, Los Angeles Dr. Caroline Y. Kuo Quest – Discovery Stage Research Projects Defining the Optimal Gene Therapy Approach of Human Hematopoietic Stem Cells for the Treatment of Dedicator of Cytokinesis 8 (DOCK8) Deficiency $1,386,232
University of California, Los Angeles Dr. Donald B Kohn MD Quest – Discovery Stage Research Projects Hematopoietic Stem Cell Gene Therapy for Alpha Thalassemia $1,177,739
Stanford University Dr. Judith A Shizuru Quest – Discovery Stage Research Projects Targeted Immunotherapy-Based Blood Stem Cell Transplantation $1,341,910
Tenaya Therapeutics, Inc. Timothy Hoey Quest – Discovery Stage Research Projects Cardiac Reprogramming Gene Therapy for Post-Myocardial Infarction Heart Failure $1,017,000
Intact Therapeutics, Inc. Jeffrey Linhardt Quest – Discovery Stage Research Projects Modulation of oral epithelium stem cells by RSpo1 for the prevention and treatment of oral mucositis $942,050
Cytonus Therapeutics, Inc. Edward Filardo Quest – Discovery Stage Research Projects Development of a novel stem-cell based carrier for intravenous delivery of oncolytic viruses $899,342
Salk Institute for Biological Studies Ronald Mark Evans Quest – Discovery Stage Research Projects Extending Immune-Evasive Human Islet-Like Organoids (HILOs) Survival and Function as a Cure for T1D $1,523,285
Stanford University Ansuman Satpathy Quest – Discovery Stage Research Projects Preclinical development of an exhaustion-resistant CAR-T stem cell for cancer immunotherapy $1,420,200
Stanford University Dr. Bertha Chen Quest – Discovery Stage Research Projects iPSC-derived smooth muscle cell progenitor conditioned medium for treatment of pelvic organ prolapse $1,420,200
University of California, San Francisco Brian Feeley Quest – Discovery Stage Research Projects Matrix Assisted Cell Transplantation of Promyogenic Fibroadipogenic Progenitor (FAP) Stem Cells $1,179,478
University of California, Los Angeles Prof. Song Li Quest – Discovery Stage Research Projects iPSC Extracellular Vesicles for Diabetes Therapy $1,354,928
Scripps Health Dr. Darryl D. D’Lima Quest – Discovery Stage Research Projects Meniscal Repair and Regeneration $1,361,775
The Stone Research Foundation for Sports Medicine and Arthritis Dr. Kevin Stone Quest – Discovery Stage Research Projects A Novel Therapy for Articular Cartilage Autologous Cellular Repair by Paste Grafting $1,180,309
University of California, San Diego Gene Wei-Ming Yeo Quest – Discovery Stage Research Projects RNA-directed therapy for Huntington’s disease $1,253,110
University of California, Irvine Dr. Mathew Mark Blurton-Jones Quest – Discovery Stage Research Projects Transplantation of genetically corrected iPSC-microglia for the treatment of Sanfilippo Syndrome (MPSIIIA) $1,083,379
University of California, San Francisco Dr. Julie Deane Saba Quest – Discovery Stage Research Projects Providing a cure for sphingosine phosphate lyase insufficiency syndrome (SPLIS) through adeno-associated viral mediated SGPL1 gene therapy $1,463,400
Scripps Research Institute Luke L Lairson Quest – Discovery Stage Research Projects Improving the efficacy and tolerability of clinically validated remyelination-inducing molecules using developable combinations of approved drugs $1,554,126
University of California, San Francisco Dr Julia Carnevale Quest – Discovery Stage Research Projects Generating deeper and more durable BCMA CAR T cell responses in Multiple Myeloma through non-viral knockin/knockout multiplexed genome engineering $1,463,368
Stanford University DR. Sarah C Heilshorn Quest – Discovery Stage Research Projects Injectable, autologous iPSC-based therapy for spinal cord injury $789,000
Navega Therapeutics Ana Maria Moreno Quest – Discovery Stage Research Projects Optimization of a gene therapy for inherited erythromelalgia in iPSC-derived neurons $1,157,313
Cedars-Sinai Medical Center Dr Eduardo Marban Quest – Discovery Stage Research Projects New noncoding RNA chemical entity for heart failure with preserved ejection fraction. $1,397,412
Stanford University Dr. Stanley Qi Quest – Discovery Stage Research Projects A novel hybrid CRISPR tool for gene network perturbation and hiPSC engineering $704,661
University of California, San Diego Ziwei Huang Quest – Discovery Stage Research Projects Development of a new therapeutic for directing target specific stem cell migration and treatment $1,129,512
University of California, San Diego Dan S Kaufman Quest – Discovery Stage Research Projects Human iPSC-derived chimeric antigen receptor expressing macrophages for improved cancer treatment. $1,256,332
Stanford University Dr. Marius Wernig MD, PhD Quest – Discovery Stage Research Projects A universally applicable skin sheet for Dystrophic Epidermolysis Bullosa via next-generation gene editing, iPS cell technology and tissue engineering $1,229,040
University of California, Davis Dr. David J Segal PhD Quest – Discovery Stage Research Projects AAV9-Cas13 gene therapy for Angelman syndrome $1,364,903
Stanford University Dr. Phillip Chung-Ming Yang Quest – Discovery Stage Research Projects Hypoxia-specific Production of Exosomes from iPSC-derivatives for Myocardial Repair $1,418,023
Stanford University Kathleen M Sakamoto Quest – Discovery Stage Research Projects Small Molecules to inhibit Nemo-like Kinase for Treatment of Diamond Blackfan Anemia $848,098
University of California, Irvine Munjal M Acharya Quest – Discovery Stage Research Projects Stem cell-derived extracellular vesicles to reverse radiation-induced brain injury $1,064,724
University of California, San Francisco Dr Marisa Medina Quest – Discovery Stage Research Projects iPSCs as a screening tool to predict risk of nonalcoholic fatty liver disease $813,000
University of California, San Diego Dr. Tannishtha Reya Quest – Discovery Stage Research Projects Targeting Critical Regulators of Cancer Stem Cells $1,148,264
University of California, Davis Dr. Deborah K Lieu Quest – Discovery Stage Research Projects Building a hiPSC-based biopacemaker $1,260,827
City of Hope, Beckman Research Institute Professor Yanhong Shi Quest – Discovery Stage Research Projects Combating COVID-19 using human PSC-derived NK cells $249,998
University of California, San Diego Tariq M Rana Quest – Discovery Stage Research Projects Development of COVID-19 Antiviral Therapy Using Human iPSC-Derived Lung Organoids $250,000
University of California, Los Angeles Dr. Thomas Carmichael M.D., Ph.D. Quest – Discovery Stage Research Projects Human-induced pluripotent stem cell-derived glial enriched progenitors to treat white matter stroke and vascular dementia. $250,000
University of California, Irvine Robert F. Hunt Quest – Discovery Stage Research Projects Optimization of a human interneuron cell therapy for traumatic brain injury $250,000
University of Southern California Dr. Justin K Ichida Quest – Discovery Stage Research Projects Development of a SYF2 antisense oligonucleotide (ASO) treatment for ALS $222,300
University of California, Irvine Dr. Mathew Mark Blurton-Jones Quest – Discovery Stage Research Projects Transplantation of Pluripotent Stem Cell Derived Microglia for the Treatment of Adult-onset Leukoencephalopathy (HDLS/ALSP) $214,668
Vitabolus, Inc. Aline Betancourt Quest – Discovery Stage Research Projects The First Orally Delivered Cell Therapy for the Treatment of Inflammatory Bowel Disease $249,000
Lundquist Institute for Biomedical Innovation at Harbor – UCLA Medical Center Eiji Yoshihara PhD Quest – Discovery Stage Research Projects Dual angiogenic and immunomodulating nanotechnology for subcutaneous stem cell derived islet transplantation for the treatment of diabetes $250,000
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