Use of stem cells in human disease modeling has reached a broader scientific audience of underserved, marginalized communities. Researchers/scholars have comprehensive training in iPSC generation, genetic modification, and differentiation techniques to model human diseases successfully. The core fills a gap for the scientific community, particularly those studying underserved populations where access to resources, training, expertise, and services for hPSCs is limited and distance and transportation costs are deterrents to stem cell research participation. The patient population, particularly those who lack equitable medical services, will benefit from the support of regenerative or modeling tools of human diseases that may have delayed diagnosis and that often lack treatments.