Hypoimmune Stem Cell–Derived Islets: A Next-Generation Cell Therapy Toward a Functional Cure for Type 1 Diabetes

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• Post published:October 6, 2026
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Regenerating the Acutely Infarcted Heart with iPSC-Ventricular Cardiomyocytes.

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• Post published:October 6, 2026
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Microglia replacement therapy for CSF1R-related Leukoencephalopathy

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• Post published:October 6, 2026
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Autologous iPSC-derived progenitor smooth muscle cells for treatment of urinary incontinence

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• Post published:October 6, 2026
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Dissecting cell-specific genetic and molecular drivers of amyotrophic lateral sclerosis for therapeutic insights

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• Post published:October 6, 2026
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Transplantation of human forebrain assembloids as a platform for therapeutic screening in neurodevelopmental disorders

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• Post published:October 6, 2026
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Advancing Therapeutic Discovery Through Multimodal Analyses of Genetic and Cellular Mechanisms in Neuropsychiatric Disorders

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• Post published:October 6, 2026
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Tracing the metabolic basis of neurological disorders

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Modeling the genetic basis of psychopathology in schizophrenia and autism

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Research Objective We propose to apply scalable platforms for the characterization of CNVs and genes coupled with detailed characterizations of neurodevelopment of the 4 major CNV loci in model systems…

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Multi-gene modulation to rescue CNS-associated microdeletion syndromes

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• Post published:October 6, 2026
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Research Objective Chromosomal microdeletion syndromes result in severe neuropsychiatric syndromes and lack therapy. This proposal will define critical genomic regions needed to generate new tools for functional rescue. Impact This…

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