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Gene Therapy for Osteoarthritis Shows Positive Results in Early Trial May 19, 2025
Here’s a shocking statistic: in 2020, 7.6% of the world’s population was living with the most common form of arthritis – osteoarthritis (OA). That amounts to 595 million people globally and 32.5 million adults in the U.S. That’s a lot of people with painful knees, hips, and other joints. Although pain medication can help with […]
20 Years of CIRM: The evolution of a CIRM-funded therapy for macular degeneration May 12, 2025
In celebration of CIRM’s 20th anniversary, we are reflecting on some of the early projects we supported that have since advanced to clinical trials. One such trial for a form of blindness originated with a 2007 SEED grant to David Hinton, MD, of the University of Southern California (USC) and later with a 2008 Disease […]
New gene therapy aims to restore function in early-onset Parkinson’s April 25, 2025
Nearly one million people in the U.S. are living with Parkinson’s disease, which causes progressive symptoms including tremors, stiffness, and gait and balance issues. Although there are medications to treat symptoms, the disease has no cure. To date, the California Institute for Regenerative Medicine (CIRM) has invested more than $109 million in helping research for […]