All CIRM Grants

Institution Researcher name Grant Type Grant Title Award Value
City of Hope Yanhong Shi Early Translational II Developing a therapeutic candidate for Canavan disease using induced pluripotent stem cell $1,835,983
Cedars-Sinai Medical Center Paul Noble Basic Biology V Innate Immune Regulation of Lung Alveolar Stem Cell Renewal in Mouse and Man $624,816
University of California, Los Angeles Samantha Butler Basic Biology V Assessing the mechanism by which the Bone Morphogenetic Proteins direct stem cell fate $545,962
University of California, Santa Cruz Lindsay Hinck Shared Labs Shared Stem Cell Facility $1,721,129
University of Southern California Mark Humayun Disease Team Therapy Development III Phase 1 Safety Assessment of CPCB-RPE1, hESC-derived RPE Cell Coated Parylene Membrane Implants, in Patients with Advanced Dry Age Related Macular Degeneration $17,128,661
University of California, San Francisco Andrew Leavitt Tools and Technologies III Small molecule tools and scale-up technologies to expand human umbilical cord blood stem and progenitor cells for clinical and research use $1,416,600
University of California, San Diego Douglas Galasko Tissue Collection for Disease Modeling Collection of skin biopsies to prepare fibroblasts from patients with Alzheimer's disease and cognitively healthy elderly controls $643,693
University of California, Los Angeles Yi Sun Basic Biology III Studying neurotransmission of normal and diseased human ES cell-derived neurons in vivo $1,382,400
University of California, San Diego Mana Parast New Faculty Physician Scientist Human pluripotent stem cell-based therapeutics for preeclampsia $2,974,750
Stanford University Judith Shizuru Disease Team Therapy Development - Research A monoclonal antibody that depletes blood stem cells and enables chemotherapy free transplants $19,068,382
University of California, San Diego Wei Wang Basic Biology V Systems-level discovery of the regulatory mechanisms directing differentiation of hESC $1,161,000
ViaCyte, Inc. Allan Robins Disease Team Research I Cell Therapy for Diabetes $22,999,933
StemCells, Inc. Alexandra Capela Disease Team Therapy Development - Research Restoration of memory in Alzheimer’s disease: a new paradigm using neural stem cell therapy $8,901,641
University of California, San Francisco Morton Cowan Early Translational III Gene Correction of Autologous Hematopoietic Stem Cells in Artemis Deficient SCID $3,931,662
University of California, Berkeley David Schaffer Shared Labs Human Embryonic Stem Cell Shared Research Laboratory $1,688,129
Buck Institute for Age Research Xianmin Zeng Shared Labs CIRM Shared Research Laboratory for Stem Cells and Aging $3,478,933
San Diego State University Ricardo Zayas New Faculty II The molecular basis underlying adult neurogenesis during regeneration and tissue renewal $1,712,225
Stanford University Gerald Crabtree Basic Biology IV Mechanism and Utility of Direct Neuronal Conversion with a MicroRNA-Chromatin Switch $1,392,426
iPierian, Inc. John Dimos Early Translational II New Drug Discovery for SMA using Patient-derived Induced Pluripotent Stem Cells $2,410,000
University of California, San Diego David Traver New Faculty I Genetic dissection of mesodermal commitment to the hematopoietic fates. $2,150,620
BioTime, Inc. Michael West Early Translational I Addressing the Cell Purity and Identity Bottleneck Through Generation and Expansion of Clonal Human Embryonic Progenitor Cell Lines $4,721,706
University of California, San Diego Karl Willert Shared Labs Enhancing Facilities for Genetic Manipulation and Engineering of Human Embryonic Stem Cells $1,728,080
Salk Institute for Biological Studies Senyon Choe SEED Grant A method to maintain and propagate pluripotent human ES cells $760,042
University of California, Los Angeles Owen Witte Basic Biology IV Trop2 dependent and independent mechanisms of self-renewal in human cancer stem cells $1,254,960
Cedars-Sinai Medical Center Eduardo Marbán Disease Team Research I Autologous cardiac-derived cells for advanced ischemic cardiomyopathy $5,560,232
Samumed, LLC John Hood Disease Team Therapy Planning I Clinical Development of an osteoinductive therapy to prevent osteoporosis-related fractures $99,110
University of California, Los Angeles Martin Martin Tools and Technologies II Pluripotent and Somatic Stem Cell Models to Study Inherited Diarrheal Disorders $1,783,250
University of California, Santa Barbara Dennis Clegg Shared Labs Laboratory for Stem Cell Biology and Engineering $1,638,357
University of California, San Diego Benjamin Yu New Faculty II Regulation of Adult Stem Cell Proliferation by RAS and Cell-Permeable Proteins $28,388
Ludwig Institute for Cancer Research Bing Ren New Faculty II Mechanisms of chromatin dynamics at enhancers during ES cell differentiation $1,726,564
Salk Institute for Biological Studies Fred Gage New Cell Lines Development of Induced Pluripotent Stem Cells for Modeling Human Disease $1,737,720
University of California, Irvine Peter Bryant Training Grant I-1 Stem Cell Research Training Grant $1,935,487
University of California, San Diego Steve Dowdy Tools and Technologies I TAT Cell-Permeable Protein Delivery of siRNAs for Epigenetic Programming of Human Pluripotent and Adult Stem Cells $720,000
University of California, San Diego Mana Parast New Faculty II Molecular Mechanisms of Trophoblast Stem Cell Specification and Self-Renewal $3,077,918
Stanford University John Hennessy Major Facilities Stanford SIM1 Building $43,578,000
University of California, Riverside Michael Pirrung SEED Grant Stem Cell Survival and Differentiation Through Chemical Genetics $522,933
University of California, San Diego Eric Adler Early Translational III Identification of Novel Therapeutics for Danon Disease Using an iPS Model of the Disease $1,701,575
University of California, San Diego Eugene Yeo Basic Biology I RNA Binding Protein-mediated Post-transcriptional Networks Regulating HPSC Pluripotency $1,308,901
University of California, Los Angeles Shuo Lin Basic Biology III Etsrp/ER71 mediated stem cell differentiation into vascular lineage $1,382,400
Palo Alto Institute for Research and Education Husein Hadeiba Transplantation Immunology Application of Tolerogenic Dendritic Cells for Hematopoietic Stem Cell Transplantation $733,061
University of California, San Diego Yang Xu Comprehensive Grant Mechanisms to maintain the self-renewal and genetic stability of human embryonic stem cells $2,467,200
ViaCyte, Inc. Emmanuel Baetge Disease Team Planning Development of a Cell Replacement Therapy Product for Insulin Dependent Diabetes $48,950
University of California, Los Angeles Noriyuki Kasahara SEED Grant Down-Regulation of Alloreactive Immune Responses to hES Cell-Derived Graft Tissues $399,239
Salk Institute for Biological Studies Ronald Evans Basic Biology II Molecular Characterization and Functional Exploration of Nuclear Receptors in hiPSCs $1,712,880
Stanford University Howard Chang New Faculty I Noncoding RNAs in Cell Fate Determination $2,985,894
Sanford-Burnham Medical Research Institute Mark Mercola Comprehensive Grant Chemical Genetic Approach to Production of hESC-derived Cardiomyocytes $2,832,000
Children's Hospital of Los Angeles Barbara Des Rochers Comprehensive Grant Regulated Expansion of Lympho-hematopoietic Stem and Progenitor Cells from Human Embryonic Stem Cells (hESC) $575,994
Stanford University Thomas Wandless SEED Grant Reprogramming Differentiated Human Cells to a Pluripotent State $380,005
University of California, San Diego Ananda Goldrath Basic Biology IV Mechanisms to protect hESC-derived cells from allogenic immune rejection $1,161,000
University of California, Davis Roslyn Isseroff Early Translational II Bone Marrow Mesenchymal Stem Cells to Heal Chronic Diabetic Wounds $4,635,576
Salk Institute for Biological Studies Lei Wang New Faculty I Genetic Encoding Novel Amino Acids in Embryonic Stem Cells for Molecular Understanding of Differentiation to Dopamine Neurons $2,587,742
University of Southern California Martin Pera New Cell Lines New Technology ForThe Derivation of Human Pluripotent Stem Cell Lines For Clinical Use $1,266,134
University of California, San Francisco Linda Giudice Shared Labs Shared Research and Teaching Laboratory: a Non-Federal Human Embryonic Stem Cell Resource for the Bay Area Community $2,144,758
Sanford-Burnham Medical Research Institute Gregg Duester SEED Grant Retinoic Acid-FGF Antagonism during Motor Neuron Differentiation of Human ES Cells $695,229
University of California, San Diego David Traver Basic Biology IV DECIPHERING THE INSTRUCTIONS FOR VERTEBRATE HSC SPECIFICATION AND AMPLIFICATION. $1,363,698
City of Hope John Zaia Disease Team Research I ZIinc Finger Nuclease-Based Stem Cell Therapy for AIDS $14,536,969
Sanford-Burnham Medical Research Institute Stuart Lipton Disease Team Therapy Planning I hESC-derived NPCs Programmed with MEF2C for Cell Transplantation in Parkinson’s Disease $96,448
Stanford University Brian Rutt Tools and Technologies II Development of Single Cell MRI Technology using Genetically-Encoded Iron-Based Reporters $1,833,348
University of California, San Diego Karl Willert Shared Labs Enhancing Facilities for Genetic Manipulation and Engineering of Human Embryonic Stem Cells $1,737,694
University of Southern California Mohammad Pashmforoush New Faculty I Transcriptional Regulation of Cardiac Pacemaker Cell Progenitors $27,949
University of California, San Diego Shyni Varghese New Faculty II A Novel Microenvironment-Mediated Functional Skeletal Muscle from Human Embryonic Stem Cells and their In Vivo Engraftment $2,300,569
University of California, San Francisco Long-cheng Li New Cell Lines Induction of pluripotent stem cells by small RNA-guided transcriptional activation $1,368,461
Scripps Research Institute Peter Schultz Training Grant I-2 Training Grant I $1,021,395
University of California, Irvine Lisa Flanagan Tools and Technologies I Novel Separation of Stem Cell Subpopulations $861,122
University of California, San Francisco Ophir Klein New Faculty II Laying the groundwork for building a tooth: analysis of dental epithelial stem cells $3,075,251
University of California, Berkeley George Breslauer Major Facilities UC Berkeley CIRM Center of Excellence $20,183,500
Sanford-Burnham Medical Research Institute Huei-sheng Chen SEED Grant Development of Neuro-Coupled Human Embryonic Stem Cell-Derived Cardiac Pacemaker Cells. $695,680
University of Southern California Toshio Miki Early Translational III Generation of hepatic cell from placental stem cell for congenital metabolic disorders $1,750,375
Scripps Research Institute Kristin Baldwin Basic Biology III Identifying sources of mutation in human induced pluripotent stem cells by whole genome sequencing $1,705,500
Escape Therapeutics, Inc Basil Hantash Transplantation Immunology Development of an immune tolerant hESC source for allogeneic cell therapy applications $1,453,040
Stanford University Julie Baker Comprehensive Grant Functional Genomic Analysis of Chemically Defined Human Embryonic Stem Cell $2,518,303
University of California, San Diego Lawrence Goldstein Disease Team Planning Human Stem Cell Approaches to Alzheimers Disease Therapies $55,000
University of California, San Francisco Heike Daldrup-Link SEED Grant Labeling of human embryonic stem cells with iron oxide nanoparticles and fluorescent dyes for a non-invasive cell depiction with MR imaging and optical imaging $240,214
iPierian, Inc. Irene Griswold-Prenner Basic Biology II Cellular Reprogramming: Dissecting the Molecular Mechanism and Enhancing Efficiency $1,458,000
University of California, Santa Cruz Bin Chen New Faculty I Molecular mechanisms of neural stem cell differentiation in the developing brain $2,147,592
University of California, Davis Jan Nolta Early Translational I Sustained siRNA production from human MSC to treat Huntingtons Disease and other neurodegenerative disorders $2,615,674
Scripps Research Institute Sheng Ding New Cell Lines Derivation of New ICM-stage hESCs $936,973
Stanford University Kenneth Weinberg SEED Grant Embryonic stem cell-derived thymic epithelial cells $628,793
Sanford-Burnham Medical Research Institute Zhuohua Zhang SEED Grant Modeling Parkinson's Disease Using Human Embryonic Stem Cells $701,060
University of California, Los Angeles Irvin Chen Disease Team Research I HPSC based therapy for HIV disease using RNAi to CCR5. $9,905,604
Cedars-Sinai Medical Center Clive Svendsen Disease Team Therapy Planning I Stem Cells Secreting GDNF for the Treatment of ALS $63,487
University of California, Berkeley David Schaffer Tools and Technologies II Engineering Defined and Scaleable Systems for Dopaminergic Neuron Differentiation of hPSCs $1,340,816
University of California, San Francisco Linda Giudice Shared Labs Shared Research and Teaching Laboratory: a Non-Federal Human Embryonic Stem Cell Resource for the Bay Area Community $3,291,268
Stanford University Michael Longaker New Cell Lines Derivation and analysis of pluripotent stem cell lines with inherited TGF-b mediated disorders from donated IVF embryos and reprogrammed adult skin fibroblasts $1,406,636
Gladstone Institutes Robert Mahley Training Grant I-2 Gladstone CIRM Scholar Program $2,192,073
University of California, San Diego Deborah Spector Basic Biology III Viral-host interactions affecting neural differentiation of human progenitors $1,372,660
ViaCyte, Inc. Evert Kroon Tools and Technologies I Development of the Theracyte Cellular Encapsulation System for Delivery of human ES Cell-derived Pancreatic Islets and Progenitors. $827,072
University of California, San Francisco Emmanuelle Passegue New Faculty II Mechanisms Underlying the Responses of Normal and Cancer Stem Cells to Environmental and Therapeutic Insults $2,124,488
University of California, Davis Larry Vanderhoef Major Facilities UC Davis CIRM Institute $20,082,400
Ludwig Institute for Cancer Research Bing Ren SEED Grant Mapping the transcriptional regulatory elements in the genome of hESC $653,823
University of California, San Francisco Arnold Kriegstein Early Translational III Human ES cell-derived MGE inhibitory interneuron transplantation for spinal cord injury $1,623,251
Stanford University Helen Blau Basic Biology I Molecular Mechanisms of Reprogramming towards Pluripotency $1,408,332
University of California, San Francisco John Murnane Basic Biology III Genomic instability during culturing of human embryonic stem cells $1,070,919
University of California, San Francisco Harold Bernstein Comprehensive Grant Modeling Myocardial Therapy with Human Embryonic Stem Cells $2,134,694
University of California, Los Angeles Irvin Chen Disease Team Planning Stem Cell Therapy for AIDS- Disease Team Planning $51,490
University of California, Los Angeles Zoran Galic SEED Grant Genetic Enhancement of the Immune Response to Melanoma via hESC-derived T cells $616,800
University of California, Davis Eric Kurzrock Basic Biology II Differentiation of Human Embryonic Stem Cells into Urothelium $849,037
University of California, Berkeley Irina Conboy New Faculty I Identification of hESC-mediated molecular mechanism that positively regulates the regenerative capacity of post-natal tissues $2,246,020
University of California, Irvine Frank LaFerla Early Translational I Neural Stem Cells as a Developmental Candidate to Treat Alzheimer Disease $3,599,997
Salk Institute for Biological Studies Garry Van Gerpen Shared Labs Shared viral vector facility for genetic manipulation of human ES cell $1,478,923

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