All CIRM Grants

Institution Researcher name Grant Type Grant Title Award Value
The J. David Gladstone Institutes Deepak Srivastava Early Translational III Direct Cardiac Reprogramming for Heart Regeneration $6,319,110
University of California, San Diego Christian Metallo Basic Biology V Metabolic regulation of cardiac differentiation and maturation $1,124,834
Asterias Biotherapeutics Jane Lebkowski Strategic Partnership III Track A A Phase I/IIa Dose Escalation Safety Study of [REDACTED] in Patients with Cervical Sensorimotor Complete Spinal Cord Injury $14,323,318
University of California, San Francisco Ann Zovein New Faculty Physician Scientist Human endothelial reprogramming for hematopoietic stem cell therapy. $2,319,784
Numerate, Inc. John Griffin Early Translational IV Use of human iPSC-derived neurons from Huntington’s Disease patients to develop novel, disease-modifying small molecule structural corrector drug candidates targeting the unique, neurotoxic conformation of mutant huntingtin $520,015
University of California, Berkeley Xavier Darzacq Research Leadership 14 Single Molecule Biophysics and Biology of Cellular Identity $4,631,091
The Salk Institute for Biological Studies Ronald Evans Basic Biology V Metabolically-driven epigenetic changes in iPSC reprogramming $1,491,900
University of California, Berkeley David Schaffer Tools and Technologies III Engineered Biomaterials for Scalable Manufacturing and High Viability Implantation of hPSC-Derived Cells to Treat Neurodegenerative Disease $1,239,276
University of California, Davis Walter Boyd Early Translational III Extracellular Matrix Bioscaffold Augmented with Human Stem Cells for Cardiovascular Repair $4,633,149
University of California, Davis John Laird Disease Team Therapy Development - Research Phase I study of IM Injection of VEGF-Producing MSC for the Treatment of Critical Limb Ischemia $12,113,602
University of Southern California Toshio Miki Early Translational III Generation of hepatic cell from placental stem cell for congenital metabolic disorders $1,750,375
University of California, Davis Vicki Wheelock Disease Team Therapy Development - Research MSC engineered to produce BDNF for the treatment of Huntington's disease $17,857,797
The Salk Institute for Biological Studies Inder Verma Early Translational IV Development of a cell and gene based therapy for hemophilia $2,298,634
University of California, San Diego Kang Zhang Tissue Collection for Disease Modeling Generation of fibroblast cell lines in patients with common blinding eye diseases $1,034,425
University of California, Los Angeles Owen Witte Shared Labs CIRM Shared Research Laboratories $1,751,297
Sanford-Burnham Medical Research Institute Evan Snyder Shared Labs Collaborative Laboratory for Human Embryonic Stem Cell Research $1,805,884
University of California, San Diego Lawrence Goldstein Basic Biology V Elucidating pathways from hereditary Alzheimer mutations to pathological tau phenotypes $1,050,300
University of California, Davis Nancy Lane Disease Team Therapy Development - Research Treatment of osteoporosis with endogenous Mesenchymal stem cells $19,999,867
University of California, Los Angeles Donald Kohn Early Translational IV Beta-Globin Gene Correction of Sickle Cell Disease in Hematopoietic Stem Cells $1,652,076
Calimmune, Inc. Geoff Symonds Disease Team Research I GENE-MODIFIED HEMATOPOIETIC STEM/PROGENITOR CELL BASED THERAPY FOR HIV DISEASE $8,278,722
University of California, San Diego Miles Wilkinson Basic Biology V New Regulators of Spermatogonial Stem Cells: RHOX Homeobox Transcription Factors $560,160
University of California, Los Angeles Gerald Lipshutz Early Translational IV Gene therapy-corrected autologous hepatocyte-like cells from induced pluripotent stem cells for the treatment of pediatric single enzyme disorders $1,801,629
Stanford University Michele Calos Tools and Technologies II Site-specific integration of Lmx1a, FoxA2, & Otx2 to optimize dopaminergic differentiation $1,592,897
Stanford University Sarah Heilshorn Tools and Technologies III Injectable Hydrogels for the Delivery, Maturation, and Engraftment of Clinically Relevant Numbers of Human Induced Pluripotent Stem Cell-Derived Neural Progenitors to the Central Nervous System $1,452,708
University of California, San Diego Alysson Muotri Early Translational IV A drug-screening platform for autism spectrum disorders using human astrocytes $1,656,456
Stanford University Alexander Dunn Basic Biology IV Role of mechanical signaling in stem cell self-renewal and differentiation $1,064,224
University of California, San Francisco Arnold Kriegstein Early Translational III Human ES cell-derived MGE inhibitory interneuron transplantation for spinal cord injury $1,623,251
Cedars-Sinai Medical Center Clive Svendsen Disease Team Therapy Development - Research Progenitor Cells Secreting GDNF for the Treatment of ALS $16,961,287
Stanford University Fan Yang Tools and Technologies III Injectable Macroporous Matrices to Enhance Stem Cell Engraftment and Survival $1,452,708
Capricor, Inc Rachel Smith Disease Team Therapy Development - Research Allogeneic Cardiac-Derived Stem Cells for Patients Following a Myocardial Infarction $19,782,136
Stanford University Alfred Lane Disease Team Research I iPS Cell-Based Treatment of Dominant Dystrophic Epidermolysis Bullosa $11,039,208
Stanford University Joseph Wu Tools and Technologies III Advanced animal model for predictive preclinical testing of engineered cardiac autografts and allografts $1,713,456
University of California, San Diego Shaochen Chen Tools and Technologies III Development of 3D Bioprinting Techniques using Human Embryonic Stem Cells Derived Cardiomyocytes for Cardiac Tissue Engineering $1,368,517
University of Southern California Mark Humayun Disease Team Therapy Development III Phase 1 Safety Assessment of CPCB-RPE1, hESC-derived RPE Cell Coated Parylene Membrane Implants, in Patients with Advanced Dry Age Related Macular Degeneration $17,128,661
Stanford University Joseph Wu Tissue Collection for Disease Modeling Tissue Collection for Accelerating iPSC Research in Cardiovascular Diseases $1,291,834
University of California, Irvine Henry Klassen Disease Team Therapy Development - Research Retinal progenitor cells for treatment of retinitis pigmentosa $17,144,825
University of California, San Francisco Morton Cowan Early Translational III Gene Correction of Autologous Hematopoietic Stem Cells in Artemis Deficient SCID $3,931,662
University of California, San Diego Deborah Spector Basic Biology III Viral-host interactions affecting neural differentiation of human progenitors $1,372,660
University of California, San Francisco Jacquelyn Maher Tissue Collection for Disease Modeling iPSC-derived Hepatocytes as Platforms for Research in Viral Hepatitis and Non-alcoholic Steatohepatitis $814,976
University of California, Los Angeles Irvin Chen Early Translational from Disease Team Conversion HPSC based therapy for HIV disease using RNAi to CCR5. $1,505,000
Sangamo BioSciences, Inc. Fyodor Urnov Strategic Partnership II A Treatment For Beta-thalassemia via High-Efficiency Targeted Genome Editing of Hematopoietic Stem Cells $6,374,150
University of California, Irvine Magdalene Seiler Early Translational IV Restoring vision by sheet transplants of retinal progenitors and retinal pigment epithelium (RPE) derived from human embryonic stem cells (hESCs) $3,998,948
University of California, San Diego Lawrence Goldstein Early Translational from Disease Team Conversion Stem Cell-Derived Astrocyte Precursor Transplants in Amyotrophic Lateral Sclerosis $3,995,136
University of California, San Diego Shyni Varghese New Faculty II A Novel Microenvironment-Mediated Functional Skeletal Muscle from Human Embryonic Stem Cells and their In Vivo Engraftment $2,300,569
University of California, San Diego Yang Xu Early Translational III Human ES cell based therapy of heart failure without allogenic immune rejection $1,857,600
University of California, Davis Deborah Lieu Basic Biology IV Induction of Pluripotent Stem Cell-Derived Pacemaking Cells $1,333,800
University of Southern California Robert Maxson Research Training II CIRM Stem Cell Biology Training Program $6,162,045
University of California, Berkeley Ellen Robey Research Training II Interdisciplinary Training in Stem Cell Biology, Engineering and Medicine $6,901,914
University of California, Berkeley Steven Conolly Tools and Technologies II Magnetic Particle Imaging: A Novel Ultra-sensitive Imaging Scanner for Tracking Stem Cells In Vivo $1,311,596
Stanford University Anthony Oro Tools and Technologies III A Chromatin Context Tool for Predicting iPS Lineage Predisposition and Tissue Graftability $1,403,822
The J. David Gladstone Institutes Benoit Bruneau Basic Biology IV Epigenetic regulation of human cardiac differentiation $1,708,560
Stanford University Michelle Monje Basic Biology IV Stem Cell Mechanisms Governing Discrete Waves of Gliogenesis in the Childhood Brain $1,264,248
University of California, San Diego Lawrence Goldstein Early Translational III Identifying Drugs for Alzheimer's Disease with Human Neurons Made From Human IPS cells $1,774,420
The Parkinson's Institute R. Jeremy Nichols Basic Biology III Understanding the role of LRRK2 in iPSC cell models of Parkinson's Disease $1,482,822
University of California, Berkeley Song Li Basic Biology III Induced Pluripotent Stem Cells for Tissue Regeneration $1,209,148
Scripps Research Institute Jeanne Loring Shared Labs Center for hESC Research $3,725,070
University of California, Irvine Lisa Flanagan Basic Biology V Molecular basis of plasma membrane characteristics reflecting stem cell fate potential $994,108
University of California, Los Angeles Kathrin Plath Basic Biology III Discovery of mechanisms that control epigenetic states in human reprogramming and pluripotent cells $1,364,598
University of California, Santa Barbara Peter Coffey Research Leadership 2 Development of Cellular Therapies for Retinal Disease $4,850,116
University of California, San Diego Mana Parast New Faculty Physician Scientist Human pluripotent stem cell-based therapeutics for preeclampsia $2,974,750
University of California, Los Angeles Samantha Butler Basic Biology V Assessing the mechanism by which the Bone Morphogenetic Proteins direct stem cell fate $545,962
Stanford University Joseph Wu Early Translational III Heart Repair with Human Tissue Engineered Myocardium $4,397,241
California State University, Long Beach Lisa Klig Bridges CIRM Stem Cell Research Biotechnology Training Program $3,513,898
University of California, Los Angeles Leif Havton Early Translational II Repair of Conus Medullaris/Cauda Equina Injury using Human ES Cell-Derived Motor Neurons $75,628
University of California, Irvine Craig Walsh Early Translational III Multiple Sclerosis therapy: Human Pluripotent Stem Cell-Derived Neural Progenitor Cells $4,590,219
University of California, Santa Cruz David Haussler Research Training II CIRM Training Program in Systems Biology of Stem cells $4,591,616
Stanford University Michelle Monje New Faculty Physician Scientist White matter neuroregeneration after chemotherapy: stem cell therapy for “chemobrain” $2,800,536
California State University, Sacramento Jane Bruner Bridges Strengthening the Pipeline of Masters-level Scientific and Laboratory Personnel in Stem Cell Research $3,113,348
Stanford University Helen Blau Early Translational III Local Delivery of Rejuvenated Old Muscle Stem Cells to Increase Strength in Aged Patients $1,825,920
Stanford University Michele Calos Early Translational IV Engineered iPSC for therapy of limb girdle muscular dystrophy type 2B $1,876,253
Stanford University Theo Palmer Research Training II CIRM Training Program $7,475,333
University of California, Los Angeles John Chute Research Leadership 14 Niche-Focused Research: Discovery & Development of Hematopoietic Regenerative Factors $5,174,715
University of California, Berkeley David Schaffer Shared Labs Human Embryonic Stem Cell Shared Research Laboratory $1,688,129
Cedars-Sinai Medical Center Robert Baloh New Faculty Physician Scientist Human iPSC modeling and therapeutics for degenerative peripheral nerve disease $3,031,737
University of California, Los Angeles Robert Reiter Early Translational IV Clinical Development of an N-cadherin Antibody to Target Cancer Stem Cells $4,075,668
University of California, Los Angeles Antoni Ribas Disease Team Therapy Development - Research Genetic Re-programming of Stem Cells to Fight Cancer $19,875,776
University of California, Los Angeles Donald Kohn Disease Team Therapy Development III Clinical Trial of Stem Cell Gene Therapy for Sickle Cell Disease $13,145,465
Scripps Research Institute Peter Schultz Early Translational II Cartilage Regeneration by the Chondrogenic Small Molecule PRO1 during Osteoarthritis $6,047,249
University of California, Los Angeles Zack Jerome Early Translational IV Stem Cell Programming With Chimeric Antigen Receptors to Eradicate HIV Infection $4,925,166
University of California, Davis Peter Belafsky Disease Team Therapy Development III Tissue Engineered Recellularized Laryngotracheal Implants $4,439,921
University of California, Santa Barbara Dennis Clegg Shared Labs Laboratory for Stem Cell Biology and Engineering $1,638,357
Stanford University Joachim Hallmayer Tissue Collection for Disease Modeling Induced pluripotent stem cells from children with autism spectrum disorders $530,265
University of California, Los Angeles Brigitte Gomperts Tissue Collection for Disease Modeling Using human induced pluripotent stem cells to improve our understanding of Idiopathic Pulmonary Fibrosis $811,231
Stanford University Roel Nusse Basic Biology IV Asymmetric stem cell division oriented by a local self-renewing signal $1,039,058
University of California, Berkeley David Schaffer Tools and Technologies II Engineering Defined and Scaleable Systems for Dopaminergic Neuron Differentiation of hPSCs $1,340,816
University of California, Berkeley Michael Rape Basic Biology III Ubiquitin-dependent control of hESC self-renewal and expansion $1,224,805
Cedars-Sinai Medical Center Barry Stripp Research Leadership 12 Epithelial progenitors and the stromal niche as therapeutic targets in lung disease $4,841,830
University of California, San Diego Wei Wang Basic Biology V Systems-level discovery of the regulatory mechanisms directing differentiation of hESC $1,161,000
University of California, Irvine leif Havton Early Translational II Repair of Conus Medullaris/Cauda Equina Injury using Human ES Cell-Derived Motor Neurons $1,538,467
University of California, Santa Barbara Dennis Clegg Research Training II Training Program in Stem Cell Biology and Engineering $2,448,823
California Polytechnic State University, San Luis Obispo Trevor Cardinal Bridges Masters of Science Specialization in Stem Cell Technology $3,542,859
California Institute of Technology David Tirrell Basic Biology V Engineered matrices for control of lineage commitment in human pancreatic stem cells $526,896
Children's Hospital of Los Angeles Tracy Grikscheit New Faculty Physician Scientist The generation and expansion of tissue-engineered small intestine from human stem/ progenitor cells: a preclinical study of functional translation $3,146,160
University of Southern California Robert Maxson Training Grant I-1 CIRM Stem Cell Biology Training Grant $2,332,431
Coriell Institute for Medical Research Dorit Berlin hPSC Repository The CIRM Human Pluripotent Stem Cell Biorepository – A Resource for Safe Storage and Distribution of High Quality iPSCs $9,942,175
University of California, Los Angeles William Lowry Basic Biology III Molecular determinants of accurate differentiation from human pluripotent stem cells $677,115
University of Southern California Qilong Ying Tools and Technologies III Embryonic stem cell-based generation of small animal models for assessing human cellular therapies $1,334,160
University of California, San Diego Maike Sander Basic Biology V Defining links between chromatin state and developmental competence $1,050,300
University of California, Berkeley Lin He New Faculty II The roles of non-coding RNAs in the self-renewal and differentiation of pluripotent stem cells $1,406,823
University of California, San Diego Shyni Varghese Tools and Technologies III Technologies to improve in vivo function of transplanted stem cells $1,393,200

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