All CIRM Grants

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Institution Researcher name Grant Type Grant Title Award Value
Cytonus Therapeutics, Inc. Dr. Edward Filardo Quest – Discovery Stage Research Projects Development of a novel stem-cell based carrier for intravenous delivery of oncolytic viruses $899,342
Salk Institute for Biological Studies Ronald Mark Evans Quest – Discovery Stage Research Projects Extending Immune-Evasive Human Islet-Like Organoids (HILOs) Survival and Function as a Cure for T1D $1,523,285
Stanford University Ansuman Satpathy Quest – Discovery Stage Research Projects Preclinical development of an exhaustion-resistant CAR-T stem cell for cancer immunotherapy $1,420,200
Stanford University Dr. Bertha Chen Quest – Discovery Stage Research Projects iPSC-derived smooth muscle cell progenitor conditioned medium for treatment of pelvic organ prolapse $1,420,200
University of California, San Francisco Brian Feeley Quest – Discovery Stage Research Projects Matrix Assisted Cell Transplantation of Promyogenic Fibroadipogenic Progenitor (FAP) Stem Cells $1,179,478
University of California, Los Angeles Prof. Song Li Quest – Discovery Stage Research Projects iPSC Extracellular Vesicles for Diabetes Therapy $1,354,928
Scripps Health Dr. Darryl D. D’Lima Quest – Discovery Stage Research Projects Meniscal Repair and Regeneration $1,361,775
The Stone Research Foundation for Sports Medicine and Arthritis Dr. Kevin Stone Quest – Discovery Stage Research Projects A Novel Therapy for Articular Cartilage Autologous Cellular Repair by Paste Grafting $1,180,309
University of California, San Diego Gene Wei-Ming Yeo Quest – Discovery Stage Research Projects RNA-directed therapy for Huntington’s disease $1,253,110
University of California, Irvine Dr. Mathew Mark Blurton-Jones Quest – Discovery Stage Research Projects Transplantation of genetically corrected iPSC-microglia for the treatment of Sanfilippo Syndrome (MPSIIIA) $1,083,379
University of California, San Francisco Dr. Julie Deane Saba Quest – Discovery Stage Research Projects Providing a cure for sphingosine phosphate lyase insufficiency syndrome (SPLIS) through adeno-associated viral mediated SGPL1 gene therapy $1,463,400
Scripps Research Institute Luke L Lairson Quest – Discovery Stage Research Projects Improving the efficacy and tolerability of clinically validated remyelination-inducing molecules using developable combinations of approved drugs $1,554,126
University of California, San Francisco Dr Julia Carnevale Quest – Discovery Stage Research Projects Generating deeper and more durable BCMA CAR T cell responses in Multiple Myeloma through non-viral knockin/knockout multiplexed genome engineering $1,463,368
Stanford University Dr. Sarah C Heilshorn Quest – Discovery Stage Research Projects Injectable, autologous iPSC-based therapy for spinal cord injury $789,000
Navega Therapeutics Ana Maria Moreno Quest – Discovery Stage Research Projects Optimization of a gene therapy for inherited erythromelalgia in iPSC-derived neurons $1,157,313
Cedars-Sinai Medical Center Dr Eduardo Marban Quest – Discovery Stage Research Projects New noncoding RNA chemical entity for heart failure with preserved ejection fraction. $1,397,412
Stanford University Dr. Stanley Qi Quest – Discovery Stage Research Projects A novel hybrid CRISPR tool for gene network perturbation and hiPSC engineering $704,661
University of California, San Diego Ziwei Huang Quest – Discovery Stage Research Projects Development of a new therapeutic for directing target specific stem cell migration and treatment $1,129,512
University of California, San Diego Dan S Kaufman Quest – Discovery Stage Research Projects Human iPSC-derived chimeric antigen receptor expressing macrophages for improved cancer treatment. $1,256,332
Stanford University Dr. Marius Wernig MD, PhD Quest – Discovery Stage Research Projects A universally applicable skin sheet for Dystrophic Epidermolysis Bullosa via next-generation gene editing, iPS cell technology and tissue engineering $1,229,040
University of California, Davis Dr. David J Segal PhD Quest – Discovery Stage Research Projects AAV9-Cas13 gene therapy for Angelman syndrome $1,364,903
Stanford University Dr. Phillip Chung-Ming Yang Quest – Discovery Stage Research Projects Hypoxia-specific Production of Exosomes from iPSC-derivatives for Myocardial Repair $1,418,023
Stanford University Kathleen M Sakamoto Quest – Discovery Stage Research Projects Small Molecules to inhibit Nemo-like Kinase for Treatment of Diamond Blackfan Anemia $847,923
University of California, Irvine Munjal M Acharya Quest – Discovery Stage Research Projects Stem cell-derived extracellular vesicles to reverse radiation-induced brain injury $1,064,724
University of California, San Francisco Dr Marisa Medina Quest – Discovery Stage Research Projects iPSCs as a screening tool to predict risk of nonalcoholic fatty liver disease $813,000
University of California, San Diego Dr. Tannishtha Reya Quest – Discovery Stage Research Projects Targeting Critical Regulators of Cancer Stem Cells $1,148,264
University of California, Davis Dr. Deborah K Lieu Quest – Discovery Stage Research Projects Building a hiPSC-based biopacemaker $1,260,827
City of Hope, Beckman Research Institute Professor Yanhong Shi Quest – Discovery Stage Research Projects Combating COVID-19 using human PSC-derived NK cells $249,998
University of California, San Diego Tariq M Rana Quest – Discovery Stage Research Projects Development of COVID-19 Antiviral Therapy Using Human iPSC-Derived Lung Organoids $250,000
University of California, Los Angeles Dr. Thomas Carmichael M.D., Ph.D. Quest – Discovery Stage Research Projects Human-induced pluripotent stem cell-derived glial enriched progenitors to treat white matter stroke and vascular dementia. $250,000
University of California, Irvine Robert F. Hunt Quest – Discovery Stage Research Projects Optimization of a human interneuron cell therapy for traumatic brain injury $240,000
University of Southern California Dr. Justin K Ichida Quest – Discovery Stage Research Projects Development of a SYF2 antisense oligonucleotide (ASO) treatment for ALS $222,300
University of California, Irvine Dr. Mathew Mark Blurton-Jones Quest – Discovery Stage Research Projects Transplantation of Pluripotent Stem Cell Derived Microglia for the Treatment of Adult-onset Leukoencephalopathy (HDLS/ALSP) $214,668
Vitabolus, Inc. Aline Betancourt Quest – Discovery Stage Research Projects The First Orally Delivered Cell Therapy for the Treatment of Inflammatory Bowel Disease $249,000
Lundquist Institute for Biomedical Innovation at Harbor – UCLA Medical Center Dr Eiji Yoshihara PhD Quest – Discovery Stage Research Projects Dual angiogenic and immunomodulating nanotechnology for subcutaneous stem cell derived islet transplantation for the treatment of diabetes $250,000
University of California, Los Angeles Dr. Donald B. Kohn Quest – Discovery Stage Research Projects Hematopoietic Stem Cell Gene Therapy for X-linked Agammaglobulinemia $219,230
University of California, San Diego Dan S Kaufman Quest – Discovery Stage Research Projects Human iPSC-derived chimeric antigen receptor-expressing macrophages for cancer treatment $222,200
Stanford University Alan G Cheng Quest – Discovery Stage Research Projects Modulation of the Wnt pathway to restore inner ear function $1,389,416
University of California, San Diego Prof James S Hagood Quest – Discovery Stage Research Projects Mesenchymal stem cell extracellular vesicles as therapy for pulmonary fibrosis $0
University of Southern California Dr. Neil Segil Quest – Discovery Stage Research Projects A screen for drugs to protect against chemotherapy-induced hearing loss, using sensory hair cells derived by direct lineage reprogramming from hiPSCs $741,574
Salk Institute for Biological Studies Ronald Mark Evans Quest – Discovery Stage Research Projects Therapeutic immune tolerant human islet-like organoids (HILOs) for Type 1 Diabetes $1,637,209
Gladstone Institutes, J. David Li Gan Quest – Discovery Stage Research Projects Develop iPSC-derived microglia to treat progranulin-deficient Frontotemporal Dementia $1,547,157
University of California, Los Angeles Dr. Lili Yang Quest – Discovery Stage Research Projects Preclinical Development of An HSC-Engineered Off-The-Shelf iNKT Cell Therapy for Cancer $1,404,000
University of California, San Diego Dr. Eric D. Adler MD Quest – Discovery Stage Research Projects Genetically Modified Hematopoietic Stem Cells for the Treatment of Danon Disease $1,393,200
Stanford University Dr. Katja Weinacht Quest – Discovery Stage Research Projects Regenerative Thymic Tissues as Curative Cell Therapy for Patients with 22q11 Deletion Syndrome $1,251,720
City of Hope, Beckman Research Institute Dr Saul J Priceman Quest – Discovery Stage Research Projects Chimeric Antigen Receptor-Engineered Stem/Memory T Cells for the Treatment of Recurrent Ovarian Cancer $1,351,174
Stanford University Dr. Philip Arden Beachy PhD Quest – Discovery Stage Research Projects Pluripotent stem cell-derived bladder epithelial progenitors for definitive cell replacement therapy of bladder cancer $1,265,436
Scripps Research Institute Stuart A Lipton Quest – Discovery Stage Research Projects Drug Development for Autism Spectrum Disorder Using Human Patient iPSCs $1,827,576
University of California, San Francisco Dr. Hideho Okada Quest – Discovery Stage Research Projects Non-viral reprogramming of the endogenous TCRα locus to direct stem memory T cells against shared neoantigens in malignant gliomas $900,000
Children’s Hospital of Los Angeles Dr. Mark R Frey Quest – Discovery Stage Research Projects Universal Pluripotent Liver Failure Therapy (UPLiFT) $1,297,512
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