University of California, Los Angeles

Total Awards: 
151
Award Value: 
$402,375,792
Institution type: 
Not for profit
Short Name: 
UCLA

Awards to the Institution

Program Investigator Award Title Award Value
Disease Team Planning Stanley Carmichael Development of a Stem Cell Therapy to Promote Functional Recovery in Stroke $42,748
Early Translational II Leif Havton Repair of Conus Medullaris/Cauda Equina Injury using Human ES Cell-Derived Motor Neurons $75,628
Inception - Discovery Stage Research Projects Bennett Novitch Organoid Modeling of Human Cortical Microcircuits $208,916
Basic Biology II Douglas Black Programs of alternative splicing regulation by polypyrimidine tract binding protein $1,344,562
Conference Dana Jones 7th CA/HSCI Junior PI Conference: Stem Cells 2.0 $2,500
Disease Team Research I Irvin Chen HPSC based therapy for HIV disease using RNAi to CCR5. $9,905,604
Conference II Song Li The 18th Annual UC System-Wide Bioengineering Symposium $25,000
SEED Grant William Lowry Modeling Human Embryonic Development with Human Embryonic Stem Cells $528,096
Quest - Discovery Stage Research Projects Lili Yang Preclinical Development of An HSC-Engineered Off-The-Shelf iNKT Cell Therapy for Cancer $1,404,000
Tools and Technologies I Hsian-Rong Tseng Microfluidic Platform for Screening Chemically Defined Conditions that Facilitate Clonal Expansion of Human Pluripotent Stem Cells $914,096
Progression Award - Discovery Stage Research Projects Caroline Kuo Evaluation of Gene Therapy Approaches for Autosomal Recessive Hyper IgE Syndrome Due to Mutations in DOCK8 $234,000
Tools and Technologies II Richard Gatti Use of hiPSCs to develop lead compounds for the treatment of genetic diseases $1,833,054
Research Training Grant William Lowry UCLA Training Program in Stem Cell Biology $5,000,000
Research Training II Kenneth Dorshkind UCLA CIRM Research Training Program II $7,790,488
Quest - Discovery Stage Research Projects Caroline Kuo Defining the Optimal Gene Therapy Approach of Human Hematopoietic Stem Cells for the Treatment of Dedicator of Cytokinesis 8 (DOCK8) Deficiency $1,386,232
New Faculty Physician Scientist Reza Ardehali Preclinical evaluation of human embryonic stem cell-derived cardiovascular progenitors in a large animal model $2,930,388
Quest - Discovery Stage Research Projects Gerald Lipshutz Gene Therapy for SLC6A8 Creatine Transporter Disorder $2,296,920
Disease Team Therapy Development III Donald Kohn Clinical Trial of Stem Cell Gene Therapy for Sickle Cell Disease $13,145,465
Therapeutic Translational Research Projects Scott Kitchen Hematopoietic Stem/Progenitor Cell-Based Chimeric Antigen Receptor Gene Therapy for HIV Infection $6,140,723
Shared Labs Scott Waugh CIRM Shared Research Laboratories $2,000,000
Tools and Technologies III Leif Havton Development of a Relevant Pre-Clinical Animal Model as a Tool to Evaluate Human Stem Cell-Derived Replacement Therapies for Motor Neuron Injuries and Degenerative Diseases $1,308,711
Inception - Discovery Stage Research Projects April Pyle Novel Platforms to Enhance In Vivo Delivery of Skeletal Muscle Progenitor Cells from Human Pluripotent Stem Cells $230,400
Basic Biology II Yong Kim Novel Mechanism in Self-Renewal/Differentiation of Human Embryonic Stem Cells $1,259,371
Conference Irvin Chen Stem Cells: A New Avenue of HIV Research and New Approaches to HIV Treatment $24,456
New Cell Lines Zack Jerome Generation of clinical grade human iPS cells $1,341,000
Inception - Discovery Stage Research Projects Alireza Moshaverinia Gingival mesenchymal stem cells as a novel treatment modality for periodontal tissue regeneration $194,483
New Faculty II Antoni Ribas Stem Cells for Immune System Regeneration to Fight Cancer $3,072,000
Therapeutic Translational Research Projects Steven Schwartz Clinical Translation of Autologous Regenerative Cell Therapy for Blindness $5,068,026
Tools and Technologies I Michael Phelps Novel Tools and Technologies for Translational PET Imaging of Cell-based Therapies $914,039
Discovery Research Projects Song Li Biomaterial vaccine to enhance the formation of SARS-CoV-2-specific T memory stem cells $149,916
Tools and Technologies II Martin Martin Pluripotent and Somatic Stem Cell Models to Study Inherited Diarrheal Disorders $1,783,250
Therapeutic Translational Research Projects Irene Llorente Clinical Translation of Allogenic Regenerative Cell Therapy for White Matter Stroke and Vascular Dementia $775,689
Disease Team Therapy Planning I Antoni Ribas Genetic Re-programming of Stem Cells to Fight Cancer $97,785
Quest - Discovery Stage Research Projects Dinesh Rao Novel methods to eliminate cancer stem cells $1,384,347
Tissue Collection for Disease Modeling Brigitte Gomperts Using human induced pluripotent stem cells to improve our understanding of Idiopathic Pulmonary Fibrosis $811,231
Quest - Discovery Stage Research Projects Richard Pietras Reversal of dysregulated myelopoiesis in breast cancers and cancer stem cells to boost antitumor immunotherapy $2,327,680
Disease Team Therapy Development III Dennis Slamon A Phase I dose escalation and expansion clinical trial of the novel first-in-class Polo-like Kinase 4 (PLK4) inhibitor, CFI-400945 in patients with advanced solid tumors $5,683,693
Therapeutic Translational Research Projects Sophie Deng Extracellular Vesicle-Based Therapy for Corneal Scars $5,779,276
Therapeutic Translational Research Projects Anthony Aldave AAV Gene Therapy for Treating Congenital Hereditary Endothelial Dystrophy associated with Biallelic SLC4A11 Mutations $4,338,166
Early Translational II Sophie Deng Regeneration of Functional Human Corneal Epithelial Progenitor Cells $697,507
Clinical Trial Stage Projects Donald Kohn A Phase I/II, Non Randomized, Multicenter, Open-Label Study of G1XCGD (Lentiviral Vector Transduced CD34+ Cells) in Patients With X-Linked Chronic Granulomatous Disease $7,083,364
Inception - Discovery Stage Research Projects Owen Witte Identification of stem cell surface markers as potential therapeutic targets for advanced prostate cancer $209,160
Basic Biology II Benhur Lee The EphrinB2/EphB4 axis in regulating hESC pluripotency and differentiation $1,371,936
Conference Tatiana Segura 2013 Materials Research Society (MRS) Spring Meeting Symposium "Design of Cell Instructive Materials" $4,000
New Cell Lines Amander Clark Generation of Pluripotent Cell Lines from Human Embryos $1,167,416
Quest - Discovery Stage Research Projects April Pyle Identification and Generation of Long Term Repopulating Human Muscle Stem Cells from Human Pluripotent Stem Cells $2,148,519
New Faculty II Brigitte Gomperts Stem Cells in Lung Cancer $2,381,572
Clinical Trial Stage Projects Theodore Nowicki Genetic Modification of Stem Cells and T cells to Activate the Immune System to Target Solid Tumors $4,230,000
Transplantation Immunology Gay Crooks Engineering Thymic Regeneration to Induce Tolerance $1,235,445
Therapeutic Translational Research Projects Vaithilingaraja Arumugaswami COVID-19 Antiviral Therapy to Block Direct Cell Injury and Associated Tissue Damage $349,999
Basic Biology III Gay Crooks Forming the Hematopoietic Niche from Human Pluripotent Stem Cells $1,252,857
Therapeutic Translational Research Projects Arjun Deb Targeting stromal progenitors to prevent the development of heart failure $4,841,428
Disease Team Therapy Planning I Stanley Nelson Combination therapy to Enhance Antisense Mediated Exon Skipping for Duchenne Muscular Dystrophy $68,947
Quest - Discovery Stage Research Projects Xian-Jie Yang Developing gene therapy for dominant optic atrophy using human pluripotent stem cell-derived retinal organoid disease models $1,345,691
Early Translational IV Robert Reiter Clinical Development of an N-cadherin Antibody to Target Cancer Stem Cells $4,075,668
Quest - Discovery Stage Research Projects Song Li Vax-CT to promote formation of cancer-specific T memory stem cell for personalized cancer immunotherapy $2,267,714
Basic Biology V Lili Yang Differentiation of Human Hematopoietic Stem Cells into iNKT Cells $614,400
SEED Grant Hanna Mikkola Improving microenvironments to promote hematopoietic stem cell development from human embryonic stem cells $550,241
Research Leadership John Chute Niche-Focused Research: Discovery & Development of Hematopoietic Regenerative Factors $4,645,297
Conference - Lung Regenerative Medicine Workshop Brigitte Gomperts Stem Cells for Lung Diseases - Overcoming Barriers to Find New Therapies $44,548
Early Translational II Noriyuki Kasahara Stem cell-based carriers for RCR vector delivery to glioblastoma $3,340,625
Conference Martina Wiedau-Pazos California ALS Summit 2011 $13,300
SEED Grant Irvin Chen Genetic modification of the human genome to resist HIV-1 infection and/or disease progression $616,800
Quest - Discovery Stage Research Projects Stanley Carmichael iPS Glial Therapy for White Matter Stroke and Vascular Dementia $2,086,130
Comprehensive Grant Gay Crooks Regulated Expansion of Lympho-hematopoietic Stem and Progenitor Cells from Human Embryonic Stem Cells (hESC) $1,653,416
Clinical Trial Stage Projects Sophie Deng Safety and Feasibility of Cultivated Autologous Limbal Stem Cells for Limbal Stem Cell Deficiency $10,301,486
New Faculty I Dana Jones Characterization of mechanisms regulating de-differentiation and the re-acquisition of stem cell identity $382,773
Discovery Research Projects Lili Yang Battling COVID-19 Using Off-The-Shelf HSC-Engineered iNKT Cells $250,000
Basic Biology III Yi Sun Studying neurotransmission of normal and diseased human ES cell-derived neurons in vivo $1,382,400
Quest - Discovery Stage Research Projects Song Li iPSC Extracellular Vesicles for Diabetes Therapy $1,354,928
Training Grant I-1 Owen Witte CIRM Type I Comprehensive Training Program $3,660,398
Quest - Discovery Stage Research Projects Lili Yang Combating Ovarian Cancer Using Stem Cell-Engineered Off-The-Shelf CAR-iNKT Cells $1,404,000
Early Translational IV Zack Jerome Stem Cell Programming With Chimeric Antigen Receptors to Eradicate HIV Infection $4,925,166
Foundation - Discovery Stage Research Projects Gay Crooks Engineering pluripotent stem cells for universally available, off-the-shelf T cell therapies $1,352,753
Basic Biology V Denis Evseenko Promoting survival and countering hypertrophy of pluripotent stem cell (PSC)-derived chondrocytes $411,330
Alpha Stem Cell Clinics John Adams UCLA-UCI Alpha Stem Cell Clinic (ASCC) Consortium $8,680,000
Therapeutic Translational Research Projects Lili Yang Stem Cell-Based iNKT Cell Therapy for Cancer $6,956,775
Basic Biology I Robb Maclellan Human Cardiovascular Progenitors, their Niches and Control of Self-renewal and Cell Fate $917,667
Quest - Discovery Stage Research Projects April Pyle CRISPR/Cas9 nanoparticle enabled therapy for Duchenne Muscular Dystrophy in muscle stem cells $2,150,400
Early Translational II Sophie Deng Regeneration of Functional Human Corneal Epithelial Progenitor Cells $1,524,947
Patent Assistance Fund Awards Adele Rennie Patent Assistance Fund - UCLA $84,973
SEED Grant Siavash Kurdistani Cellular epigenetic diversity as a blueprint for defining the identity and functional potential of human embryonic stem cells $549,698
Quest - Discovery Stage Research Projects Scott Kitchen Engineering Lifelong Cellular Immunity to HIV $1,701,178
Comprehensive Grant Zack Jerome Human Embryonic Stem Cell Therapeutic Strategies to Target HIV Disease $2,401,903
Therapeutic Translational Research Projects Caroline Kuo Ex Vivo Gene Editing of Human Hematopoietic Stem Cells for the Treatment of X-Linked Hyper-IgM Syndrome $4,896,628
New Faculty I Siavash Kurdistani Epigenetics in cancer stem cell initiation and clinical outcome prediction $3,063,450
Quest - Discovery Stage Research Projects Donald Kohn Hematopoietic Stem Cell Gene Therapy for X-linked Agammaglobulinemia $219,230
Basic Biology III Ali Nsair Characterization and Engineering of the Cardiac Stem Cell Niche $1,127,741
Clinical Trial Stage Projects Donald Kohn Efficacy and safety of cryopreserved autologous CD34+ HSC transduced with EFS lentiviral vector encoding for human ADA gene in ADA-SCID subjects $5,827,000
Disease Team Therapy Development - Research Antoni Ribas Genetic Re-programming of Stem Cells to Fight Cancer $14,144,221
COMPASS Training Grant Tracy Johnson COMPASS: Accelerating Stem Cell Research by Educating and Empowering New Stem Cell Researchers $2,910,000
Early Translational IV Donald Kohn Beta-Globin Gene Correction of Sickle Cell Disease in Hematopoietic Stem Cells $1,651,884
Foundation - Discovery Stage Research Projects Brigitte Gomperts Overcoming barriers for airway stem cell gene therapy for Cystic Fibrosis $1,472,858
Basic Biology V Bennett Novitch In vitro modeling of human motor neuron disease $1,147,114
Tools and Technologies III Hanna Mikkola A suite of engineered human pluripotent stem cell lines to facilitate the generation of hematopoietic stem cells $1,382,400
Conference II Donald Kohn Primary Immune Deficiency Treatment Consortium (PIDTC) Annual Scientific Workshop $29,807
Basic Biology I Luisa Iruela-Arispe Molecular Characterization and Functional Exploration of Hemogenic Endothelium $1,371,477
Clinical Trial Stage Projects Donald Kohn Efficacy and safety of cryopreserved autologous CD34+ HSC transduced with EFS lentiviral vector encoding for human ADA gene in ADA-SCID subjects $10,156,925
Early Translational II Bruno Peault Harnessing native fat-residing stem cells for bone regeneration $5,359,076
Quest - Discovery Stage Research Projects Caroline Kuo Targeted Gene Editing in the Treatment of X-Linked Hyper-IgM Syndrome $1,512,333
SEED Grant Noriyuki Kasahara Down-Regulation of Alloreactive Immune Responses to hES Cell-Derived Graft Tissues $399,239
Conference - The 2018 Alpha Stem Cell Clinic Annual Symposium John Adams Delivery of Stem Cell Therapeutics to Patients $60,000
Comprehensive Grant Guoping Fan Epigenetic gene regulation during the differentiation of human embryonic stem cells: Impact on neural repair $2,412,995
Therapeutic Translational Research Projects Yvonne Chen BCMA/CS1 Bispecific CAR-T Cell Therapy to Prevent Antigen Escape in Multiple Myeloma $3,176,805
New Faculty I Hanna Mikkola Mechanisms of Hematopoietic stem cell Specification and Self-Renewal $2,286,900
Quest - Discovery Stage Research Projects Stanley Carmichael Human-induced pluripotent stem cell-derived glial enriched progenitors to treat white matter stroke and vascular dementia. $250,000
Basic Biology III Kathrin Plath Discovery of mechanisms that control epigenetic states in human reprogramming and pluripotent cells $1,364,598
Late Stage Preclinical Projects Antoni Ribas Skin regeneration and wound healing with a topical BRAF inhibitor $5,005,126
Basic Biology IV Kathrin Plath Understanding the status of the X chromosomes in human ESCs and preimplantation embryos $1,382,400
Foundation - Discovery Stage Research Projects Melissa Spencer Engineering AAV capsids for transduction of neural and muscle stem cells $999,999
Early Translational IV Gerald Lipshutz Gene therapy-corrected autologous hepatocyte-like cells from induced pluripotent stem cells for the treatment of pediatric single enzyme disorders $1,801,629
Foundation - Discovery Stage Research Projects Kathrin Plath Characterization and applications of human blastoids for understanding early human embryogenesis $1,402,137
Basic Biology V Samantha Butler Assessing the mechanism by which the Bone Morphogenetic Proteins direct stem cell fate $515,730
Tools and Technologies III James Dunn Skin-derived precursor cells for the treatment of enteric neuromuscular dysfunction $1,044,423
Inception - Discovery Stage Research Projects Stanley Carmichael iPS-Interneuron Transplantation for Neural Repair after Stroke $229,396
Basic Biology I Bennett Novitch Molecular Characterization of hESC and hIPSC-Derived Spinal Motor Neurons $1,228,278
Quest - Discovery Stage Research Projects John Chute Protein tyrosine phosphatase - sigma inhibitors for hematopoietic regeneration $2,115,735
Disease Team Research I Dennis Slamon Therapeutic Opportunities To Target Tumor Initiating Cells in Solid Tumors $19,979,660
Quest - Discovery Stage Research Projects Gay Crooks Platform Technology for Pluripotent Stem Cell-Derived T cell Immunotherapy $965,636
SEED Grant Zoran Galic Genetic Enhancement of the Immune Response to Melanoma via hESC-derived T cells $616,800
Therapeutic Translational Research Projects Peter Butler Personalized Cell Therapy for Diabetes $1,494,896
Early Translational I Gabriel Travis Development of a Stem Cell-based Transplantation Strategy for Treating Age-related Macular Degeneration $5,487,136
Discovery Research Projects Brigitte Gomperts Identifying a lead compound for COVID19 using high throughput screening with lung stem cell organoids $149,998
New Faculty I Kathrin Plath In vitro reprogramming of mouse and human somatic cells to an embryonic state $2,229,427
Therapeutic Translational Research Projects Lili Yang HSC-Engineered Off-The-Shelf CAR-iNKT Cell Therapy for Multiple Myeloma $5,281,199
Basic Biology III William Lowry Molecular determinants of accurate differentiation from human pluripotent stem cells $677,115
Therapeutic Translational Research Projects Donald Kohn Autologous MPO Knock-Out Hematopoietic Stem and Progenitor Cells for Pulmonary Arterial Hypertension $4,751,297
Basic Biology IV Owen Witte Trop2 dependent and independent mechanisms of self-renewal in human cancer stem cells $1,254,960
Alpha Stem Cell Clinics Network Expansion Noah Federman Expansion of the Alpha Stem Cell and Gene Therapy Clinic at UCLA $8,000,000
Early Translational from Disease Team Conversion Stanley Nelson Combination therapy to Enhance Antisense Mediated Exon Skipping for Duchenne Muscular Dystrophy $1,823,545
Foundation - Discovery Stage Research Projects William Lowry Defining the source of dysfunction in monogenic Intellectual Disability Syndrome neurons $1,500,337
Major Facilities Gene Block UCLA CIRM Institute $19,854,900
Tools and Technologies III Carla Koehler A small molecule tool for reducing the malignant potential in reprogramming human iPSCs and ESCs $1,283,900
Inception - Discovery Stage Research Projects Arjun Deb Targeting progenitors in scar tissue to reduce chronic scar burden $230,400
Basic Biology I Michael Teitell Mitochondrial Metabolism in hESC and hiPSC Differentiation, Reprogramming, and Cancer $1,323,029
Late Stage Preclinical Projects Sophie Deng Regeneration of a Normal Corneal Surface by Limbal Stem Cell Therapy $4,244,211
Disease Team Research I Donald Kohn Stem Cell Gene Therapy for Sickle Cell Disease $8,833,695
Quest - Discovery Stage Research Projects Vaithilingaraja Arumugaswami Immunization strategies to prevent Zika viral congenital eye and brain disease $2,128,867
SEED Grant Michael Teitell Role of Mitochondria in Self-Renewal Versus Differentiation of Human Embryonic Stem Cells $543,274
Clinical Trial Stage Projects Steven Dubinett A phase I trial of intratumoral administration of CCL21-gene modified dendritic cell (DC) combined with intravenous pembrolizumab for advanced NSCLC $10,955,315
Shared Labs Owen Witte CIRM Shared Research Laboratories $1,751,297
Discovery Research Projects Gay Crooks Stem cell-based rapid identification of SARS-CoV-2 T cell epitopes and T cell receptors for therapeutic use $126,692
Tools and Technologies II Stanley Carmichael Development of a Hydrogel Matrix for Stem Cell Growth and Neural Repair after Stroke $1,825,613
Therapeutic Translational Research Projects Cristina Puig Saus CAR-Tnm cell therapy for melanoma targeting TYRP-1 $5,904,462
Basic Biology III Shuo Lin Etsrp/ER71 mediated stem cell differentiation into vascular lineage $1,378,781
Quest - Discovery Stage Research Projects Donald Kohn Hematopoietic Stem Cell Gene Therapy for Alpha Thalassemia $1,177,739
New Faculty Physician Scientist Ali Nsair Human Induced Pluripotent Stem Cell-Derived Cardiovascular Progenitor Cells for Cardiac Cell Therapy. $2,316,894
Quest - Discovery Stage Research Projects Frank Pajonk Development of novel small molecules against cancer stem cells in solid cancers $2,340,000
Early Translational from Disease Team Conversion Irvin Chen Development of a humanized mouse model for testing anti-HIV HSPC gene therapy strategies in HIV-1 infected mice. $1,505,000
Late Stage Preclinical Projects Steven Schwartz Clinical Translation of Autologous Regenerative Pluripotent Stem Cell Therapy for Blindness $6,000,000
Disease Team Planning Irvin Chen Stem Cell Therapy for AIDS- Disease Team Planning $51,490
Total:
$402,375,793.00
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