University of California, Los Angeles

Total Awards: 
116
Award Value: 
$306,189,769
Institution type: 
Not for profit
Short Name: 
UCLA

Awards to the Institution

Program Investigator Award Title Award Value
Clinical Trial Stage Projects Sophie Deng Safety and Feasibility of Cultivated Autologous Limbal Stem Cells for Limbal Stem Cell Deficiency $10,301,486
New Faculty I Dana Jones Characterization of mechanisms regulating de-differentiation and the re-acquisition of stem cell identity $382,773
Basic Biology III Yi Sun Studying neurotransmission of normal and diseased human ES cell-derived neurons in vivo $1,382,400
Training Grant I-1 Owen Witte CIRM Type I Comprehensive Training Program $3,660,398
Early Translational IV Zack Jerome Stem Cell Programming With Chimeric Antigen Receptors to Eradicate HIV Infection $4,925,166
Basic Biology V Denis Evseenko Promoting survival and countering hypertrophy of pluripotent stem cell (PSC)-derived chondrocytes $411,330
SEED Grant Hanna Mikkola Improving microenvironments to promote hematopoietic stem cell development from human embryonic stem cells $550,241
Research Leadership John Chute Niche-Focused Research: Discovery & Development of Hematopoietic Regenerative Factors $4,645,297
Conference - Lung Regenerative Medicine Workshop Brigitte Gomperts Stem Cells for Lung Diseases - Overcoming Barriers to Find New Therapies $44,548
Early Translational II Noriyuki Kasahara Stem cell-based carriers for RCR vector delivery to glioblastoma $3,340,625
Conference Martina Wiedau-Pazos California ALS Summit 2011 $13,300
SEED Grant Irvin Chen Genetic modification of the human genome to resist HIV-1 infection and/or disease progression $616,800
Quest - Discovery Stage Research Projects Stanley Carmichael iPS Glial Therapy for White Matter Stroke and Vascular Dementia $2,096,095
Comprehensive Grant Gay Crooks Regulated Expansion of Lympho-hematopoietic Stem and Progenitor Cells from Human Embryonic Stem Cells (hESC) $1,653,416
Therapeutic Translational Research Projects Caroline Kuo Ex Vivo Gene Editing of Human Hematopoietic Stem Cells for the Treatment of X-Linked Hyper-IgM Syndrome $4,896,628
New Faculty I Siavash Kurdistani Epigenetics in cancer stem cell initiation and clinical outcome prediction $3,063,450
Basic Biology III Ali Nsair Characterization and Engineering of the Cardiac Stem Cell Niche $1,127,741
Disease Team Therapy Development - Research Antoni Ribas Genetic Re-programming of Stem Cells to Fight Cancer $14,144,221
Early Translational IV Donald Kohn Beta-Globin Gene Correction of Sickle Cell Disease in Hematopoietic Stem Cells $1,652,076
Basic Biology V Bennett Novitch In vitro modeling of human motor neuron disease $1,148,758
Alpha Stem Cell Clinics John Adams UCLA-UCI Alpha Stem Cell Clinic (ASCC) Consortium $8,000,000
Therapeutic Translational Research Projects Lili Yang Stem Cell-Based iNKT Cell Therapy for Cancer $6,956,775
Basic Biology I Robb Maclellan Human Cardiovascular Progenitors, their Niches and Control of Self-renewal and Cell Fate $917,667
Quest - Discovery Stage Research Projects April Pyle CRISPR/Cas9 nanoparticle enabled therapy for Duchenne Muscular Dystrophy in muscle stem cells $2,150,400
Early Translational II Sophie Deng Regeneration of Functional Human Corneal Epithelial Progenitor Cells $1,524,947
Patent Assistance Fund Awards Adele Rennie Patent Assistance Fund - UCLA $84,973
SEED Grant Siavash Kurdistani Cellular epigenetic diversity as a blueprint for defining the identity and functional potential of human embryonic stem cells $549,698
Quest - Discovery Stage Research Projects Scott Kitchen Engineering Lifelong Cellular Immunity to HIV $1,701,178
Comprehensive Grant Zack Jerome Human Embryonic Stem Cell Therapeutic Strategies to Target HIV Disease $2,401,903
Therapeutic Translational Research Projects Yvonne Chen BCMA/CS1 Bispecific CAR-T Cell Therapy to Prevent Antigen Escape in Multiple Myeloma $3,176,805
New Faculty I Hanna Mikkola Mechanisms of Hematopoietic stem cell Specification and Self-Renewal $2,286,900
Basic Biology III Kathrin Plath Discovery of mechanisms that control epigenetic states in human reprogramming and pluripotent cells $1,364,598
Basic Biology IV Kathrin Plath Understanding the status of the X chromosomes in human ESCs and preimplantation embryos $1,382,400
Early Translational IV Gerald Lipshutz Gene therapy-corrected autologous hepatocyte-like cells from induced pluripotent stem cells for the treatment of pediatric single enzyme disorders $1,801,629
Basic Biology V Samantha Butler Assessing the mechanism by which the Bone Morphogenetic Proteins direct stem cell fate $515,730
Tools and Technologies III Hanna Mikkola A suite of engineered human pluripotent stem cell lines to facilitate the generation of hematopoietic stem cells $1,382,400
Conference II Donald Kohn Primary Immune Deficiency Treatment Consortium (PIDTC) Annual Scientific Workshop $29,807
Basic Biology I Luisa Iruela-Arispe Molecular Characterization and Functional Exploration of Hemogenic Endothelium $1,371,477
Clinical Trial Stage Projects Donald Kohn Efficacy and safety of cryopreserved autologous CD34+ HSC transduced with EFS lentiviral vector encoding for human ADA gene in ADA-SCID subjects $10,156,925
Early Translational II Bruno Peault Harnessing native fat-residing stem cells for bone regeneration $5,359,076
Quest - Discovery Stage Research Projects Caroline Kuo Targeted Gene Editing in the Treatment of X-Linked Hyper-IgM Syndrome $1,512,333
SEED Grant Noriyuki Kasahara Down-Regulation of Alloreactive Immune Responses to hES Cell-Derived Graft Tissues $399,239
Conference - The 2018 Alpha Stem Cell Clinic Annual Symposium John Adams Delivery of Stem Cell Therapeutics to Patients $60,000
Comprehensive Grant Guoping Fan Epigenetic gene regulation during the differentiation of human embryonic stem cells: Impact on neural repair $2,412,995
Early Translational I Gabriel Travis Development of a Stem Cell-based Transplantation Strategy for Treating Age-related Macular Degeneration $5,487,136
Discovery Research Projects Brigitte Gomperts Identifying a lead compound for COVID19 using high throughput screening with lung stem cell organoids $149,998
New Faculty I Kathrin Plath In vitro reprogramming of mouse and human somatic cells to an embryonic state $2,229,427
Basic Biology III William Lowry Molecular determinants of accurate differentiation from human pluripotent stem cells $677,115
Basic Biology IV Owen Witte Trop2 dependent and independent mechanisms of self-renewal in human cancer stem cells $1,254,960
Early Translational from Disease Team Conversion Stanley Nelson Combination therapy to Enhance Antisense Mediated Exon Skipping for Duchenne Muscular Dystrophy $1,823,545
Major Facilities Gene Block UCLA CIRM Institute $19,854,900
Tools and Technologies III James Dunn Skin-derived precursor cells for the treatment of enteric neuromuscular dysfunction $1,044,423
Inception - Discovery Stage Research Projects Stanley Carmichael iPS-Interneuron Transplantation for Neural Repair after Stroke $229,396
Basic Biology I Bennett Novitch Molecular Characterization of hESC and hIPSC-Derived Spinal Motor Neurons $1,229,922
Quest - Discovery Stage Research Projects John Chute Protein tyrosine phosphatase - sigma inhibitors for hematopoietic regeneration $2,116,708
Disease Team Research I Dennis Slamon Therapeutic Opportunities To Target Tumor Initiating Cells in Solid Tumors $19,979,660
Quest - Discovery Stage Research Projects Gay Crooks Platform Technology for Pluripotent Stem Cell-Derived T cell Immunotherapy $965,636
SEED Grant Zoran Galic Genetic Enhancement of the Immune Response to Melanoma via hESC-derived T cells $616,800
Therapeutic Translational Research Projects Peter Butler Personalized Cell Therapy for Diabetes $1,494,896
Shared Labs Owen Witte CIRM Shared Research Laboratories $1,751,297
Discovery Research Projects Gay Crooks Stem cell-based rapid identification of SARS-CoV-2 T cell epitopes and T cell receptors for therapeutic use $126,692
Tools and Technologies II Stanley Carmichael Development of a Hydrogel Matrix for Stem Cell Growth and Neural Repair after Stroke $1,825,613
Basic Biology III Shuo Lin Etsrp/ER71 mediated stem cell differentiation into vascular lineage $1,378,781
New Faculty Physician Scientist Ali Nsair Human Induced Pluripotent Stem Cell-Derived Cardiovascular Progenitor Cells for Cardiac Cell Therapy. $2,316,894
Early Translational from Disease Team Conversion Irvin Chen Development of a humanized mouse model for testing anti-HIV HSPC gene therapy strategies in HIV-1 infected mice. $1,505,000
Disease Team Planning Irvin Chen Stem Cell Therapy for AIDS- Disease Team Planning $51,490
Tools and Technologies III Carla Koehler A small molecule tool for reducing the malignant potential in reprogramming human iPSCs and ESCs $1,283,900
Inception - Discovery Stage Research Projects Arjun Deb Targeting progenitors in scar tissue to reduce chronic scar burden $230,400
Basic Biology I Michael Teitell Mitochondrial Metabolism in hESC and hiPSC Differentiation, Reprogramming, and Cancer $1,323,029
Late Stage Preclinical Projects Sophie Deng Regeneration of a Normal Corneal Surface by Limbal Stem Cell Therapy $4,244,211
Disease Team Research I Donald Kohn Stem Cell Gene Therapy for Sickle Cell Disease $8,833,695
Quest - Discovery Stage Research Projects Vaithilingaraja Arumugaswami Immunization strategies to prevent Zika viral congenital eye and brain disease $2,128,867
SEED Grant Michael Teitell Role of Mitochondria in Self-Renewal Versus Differentiation of Human Embryonic Stem Cells $543,274
Clinical Trial Stage Projects Steven Dubinett A phase I trial of intratumoral administration of CCL21-gene modified dendritic cell (DC) combined with intravenous pembrolizumab for advanced NSCLC $10,955,315
Quest - Discovery Stage Research Projects Lili Yang Preclinical Development of An HSC-Engineered Off-The-Shelf iNKT Cell Therapy for Cancer $1,404,000
Tools and Technologies I Hsian-Rong Tseng Microfluidic Platform for Screening Chemically Defined Conditions that Facilitate Clonal Expansion of Human Pluripotent Stem Cells $914,096
Tools and Technologies II Richard Gatti Use of hiPSCs to develop lead compounds for the treatment of genetic diseases $1,833,054
Research Training II Kenneth Dorshkind UCLA CIRM Research Training Program II $7,790,488
New Faculty Physician Scientist Reza Ardehali Preclinical evaluation of human embryonic stem cell-derived cardiovascular progenitors in a large animal model $2,930,388
Disease Team Therapy Development III Donald Kohn Clinical Trial of Stem Cell Gene Therapy for Sickle Cell Disease $13,145,465
Disease Team Planning Stanley Carmichael Development of a Stem Cell Therapy to Promote Functional Recovery in Stroke $42,748
Early Translational II Leif Havton Repair of Conus Medullaris/Cauda Equina Injury using Human ES Cell-Derived Motor Neurons $75,628
Inception - Discovery Stage Research Projects Bennett Novitch Organoid Modeling of Human Cortical Microcircuits $208,916
Basic Biology II Douglas Black Programs of alternative splicing regulation by polypyrimidine tract binding protein $1,344,562
Conference Dana Jones 7th CA/HSCI Junior PI Conference: Stem Cells 2.0 $2,500
Disease Team Research I Irvin Chen HPSC based therapy for HIV disease using RNAi to CCR5. $9,905,604
Conference II Song Li The 18th Annual UC System-Wide Bioengineering Symposium $25,000
SEED Grant William Lowry Modeling Human Embryonic Development with Human Embryonic Stem Cells $528,096
Therapeutic Translational Research Projects Steven Schwartz Clinical Translation of Autologous Regenerative Cell Therapy for Blindness $5,068,026
Tools and Technologies I Michael Phelps Novel Tools and Technologies for Translational PET Imaging of Cell-based Therapies $914,039
Tools and Technologies II Martin Martin Pluripotent and Somatic Stem Cell Models to Study Inherited Diarrheal Disorders $1,783,250
Disease Team Therapy Planning I Antoni Ribas Genetic Re-programming of Stem Cells to Fight Cancer $97,785
Tissue Collection for Disease Modeling Brigitte Gomperts Using human induced pluripotent stem cells to improve our understanding of Idiopathic Pulmonary Fibrosis $811,231
Disease Team Therapy Development III Dennis Slamon A Phase I dose escalation and expansion clinical trial of the novel first-in-class Polo-like Kinase 4 (PLK4) inhibitor, CFI-400945 in patients with advanced solid tumors $5,683,693
Shared Labs Scott Waugh CIRM Shared Research Laboratories $2,000,000
Tools and Technologies III Leif Havton Development of a Relevant Pre-Clinical Animal Model as a Tool to Evaluate Human Stem Cell-Derived Replacement Therapies for Motor Neuron Injuries and Degenerative Diseases $1,308,711
Inception - Discovery Stage Research Projects April Pyle Novel Platforms to Enhance In Vivo Delivery of Skeletal Muscle Progenitor Cells from Human Pluripotent Stem Cells $230,400
Basic Biology II Yong Kim Novel Mechanism in Self-Renewal/Differentiation of Human Embryonic Stem Cells $1,259,371
Conference Irvin Chen Stem Cells: A New Avenue of HIV Research and New Approaches to HIV Treatment $24,456
New Cell Lines Zack Jerome Generation of clinical grade human iPS cells $1,341,000
Inception - Discovery Stage Research Projects Alireza Moshaverinia Gingival mesenchymal stem cells as a novel treatment modality for periodontal tissue regeneration $194,483
New Faculty II Antoni Ribas Stem Cells for Immune System Regeneration to Fight Cancer $3,072,000
Clinical Trial Stage Projects Theodore Nowicki Genetic Modification of Stem Cells and T cells to Activate the Immune System to Target Solid Tumors $4,693,839
Transplantation Immunology Gay Crooks Engineering Thymic Regeneration to Induce Tolerance $1,235,445
Basic Biology III Gay Crooks Forming the Hematopoietic Niche from Human Pluripotent Stem Cells $1,252,857
Disease Team Therapy Planning I Stanley Nelson Combination therapy to Enhance Antisense Mediated Exon Skipping for Duchenne Muscular Dystrophy $68,947
Early Translational IV Robert Reiter Clinical Development of an N-cadherin Antibody to Target Cancer Stem Cells $4,075,668
Basic Biology V Lili Yang Differentiation of Human Hematopoietic Stem Cells into iNKT Cells $614,400
Early Translational II Sophie Deng Regeneration of Functional Human Corneal Epithelial Progenitor Cells $697,507
Clinical Trial Stage Projects Donald Kohn A Phase I/II, Non Randomized, Multicenter, Open-Label Study of G1XCGD (Lentiviral Vector Transduced CD34+ Cells) in Patients With X-Linked Chronic Granulomatous Disease $7,083,364
Inception - Discovery Stage Research Projects Owen Witte Identification of stem cell surface markers as potential therapeutic targets for advanced prostate cancer $209,160
Basic Biology II Benhur Lee The EphrinB2/EphB4 axis in regulating hESC pluripotency and differentiation $1,371,936
Conference Tatiana Segura 2013 Materials Research Society (MRS) Spring Meeting Symposium "Design of Cell Instructive Materials" $4,000
New Cell Lines Amander Clark Generation of Pluripotent Cell Lines from Human Embryos $1,168,501
Quest - Discovery Stage Research Projects April Pyle Identification and Generation of Long Term Repopulating Human Muscle Stem Cells from Human Pluripotent Stem Cells $2,184,000
New Faculty II Brigitte Gomperts Stem Cells in Lung Cancer $2,381,572
Total:
$306,189,770.00
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