University of California, Los Angeles

Total Awards: 
110
Award Value: 
$287,652,615
Institution type: 
Not for profit
Short Name: 
UCLA

Awards to the Institution

Program Investigator Award Title Award Value
SEED Grant Irvin Chen Genetic modification of the human genome to resist HIV-1 infection and/or disease progression $616,800
Training Grant I-1 Owen Witte CIRM Type I Comprehensive Training Program $3,660,398
Research Leadership John Chute Niche-Focused Research: Discovery & Development of Hematopoietic Regenerative Factors $5,174,715
Conference Dana Jones 7th CA/HSCI Junior PI Conference: Stem Cells 2.0 $2,500
Tools and Technologies I Hsian-Rong Tseng Microfluidic Platform for Screening Chemically Defined Conditions that Facilitate Clonal Expansion of Human Pluripotent Stem Cells $914,096
Disease Team Therapy Development III Donald Kohn Clinical Trial of Stem Cell Gene Therapy for Sickle Cell Disease $13,145,465
Early Translational II Bruno Peault Harnessing native fat-residing stem cells for bone regeneration $5,359,076
Conference - The 2018 Alpha Stem Cell Clinic Annual Symposium John Adams Delivery of Stem Cell Therapeutics to Patients $60,000
Basic Biology III Kathrin Plath Discovery of mechanisms that control epigenetic states in human reprogramming and pluripotent cells $1,364,598
Tools and Technologies III Hanna Mikkola A suite of engineered human pluripotent stem cell lines to facilitate the generation of hematopoietic stem cells $1,382,400
Inception - Discovery Stage Research Projects Owen Witte Identification of stem cell surface markers as potential therapeutic targets for advanced prostate cancer $209,160
New Faculty II Brigitte Gomperts Stem Cells in Lung Cancer $2,381,572
Early Translational IV Robert Reiter Clinical Development of an N-cadherin Antibody to Target Cancer Stem Cells $4,075,668
Quest - Discovery Stage Research Projects Vaithilingaraja Arumugaswami Immunization strategies to prevent Zika viral congenital eye and brain disease $2,128,867
Tools and Technologies II Stanley Carmichael Development of a Hydrogel Matrix for Stem Cell Growth and Neural Repair after Stroke $1,825,613
Disease Team Planning Irvin Chen Stem Cell Therapy for AIDS- Disease Team Planning $51,490
Basic Biology I Michael Teitell Mitochondrial Metabolism in hESC and hiPSC Differentiation, Reprogramming, and Cancer $1,323,029
SEED Grant Siavash Kurdistani Cellular epigenetic diversity as a blueprint for defining the identity and functional potential of human embryonic stem cells $549,698
Disease Team Therapy Development - Research Antoni Ribas Genetic Re-programming of Stem Cells to Fight Cancer $19,875,776
Therapeutic Translational Research Projects Lili Yang Stem Cell-Based iNKT Cell Therapy for Cancer $6,956,775
Conference Irvin Chen Stem Cells: A New Avenue of HIV Research and New Approaches to HIV Treatment $24,456
Tools and Technologies I Michael Phelps Novel Tools and Technologies for Translational PET Imaging of Cell-based Therapies $914,039
Disease Team Therapy Development III Dennis Slamon A Phase I dose escalation and expansion clinical trial of the novel first-in-class Polo-like Kinase 4 (PLK4) inhibitor, CFI-400945 in patients with advanced solid tumors $5,683,693
Disease Team Research I Dennis Slamon Therapeutic Opportunities To Target Tumor Initiating Cells in Solid Tumors $19,979,660
Therapeutic Translational Research Projects Peter Butler Personalized Cell Therapy for Diabetes $4,230,186
Basic Biology III William Lowry Molecular determinants of accurate differentiation from human pluripotent stem cells $677,115
Tools and Technologies III James Dunn Skin-derived precursor cells for the treatment of enteric neuromuscular dysfunction $1,044,423
Conference - Lung Regenerative Medicine Workshop Brigitte Gomperts Stem Cells for Lung Diseases - Overcoming Barriers to Find New Therapies $44,548
Comprehensive Grant Gay Crooks Regulated Expansion of Lympho-hematopoietic Stem and Progenitor Cells from Human Embryonic Stem Cells (hESC) $1,653,416
Early Translational IV Zack Jerome Stem Cell Programming With Chimeric Antigen Receptors to Eradicate HIV Infection $4,925,166
Basic Biology II Douglas Black Programs of alternative splicing regulation by polypyrimidine tract binding protein $1,344,562
Conference II Song Li The 18th Annual UC System-Wide Bioengineering Symposium $25,000
Tools and Technologies II Richard Gatti Use of hiPSCs to develop lead compounds for the treatment of genetic diseases $1,833,054
Disease Team Planning Stanley Carmichael Development of a Stem Cell Therapy to Promote Functional Recovery in Stroke $42,748
SEED Grant Noriyuki Kasahara Down-Regulation of Alloreactive Immune Responses to hES Cell-Derived Graft Tissues $399,239
Basic Biology IV Kathrin Plath Understanding the status of the X chromosomes in human ESCs and preimplantation embryos $1,382,400
Conference II Donald Kohn Primary Immune Deficiency Treatment Consortium (PIDTC) Annual Scientific Workshop $29,807
Conference Tatiana Segura 2013 Materials Research Society (MRS) Spring Meeting Symposium "Design of Cell Instructive Materials" $4,000
Transplantation Immunology Gay Crooks Engineering Thymic Regeneration to Induce Tolerance $1,235,445
Basic Biology V Lili Yang Differentiation of Human Hematopoietic Stem Cells into iNKT Cells $614,400
Disease Team Research I Donald Kohn Stem Cell Gene Therapy for Sickle Cell Disease $8,833,695
Clinical Trial Stage Projects Steven Dubinett A phase I trial of intratumoral administration of CCL21-gene modified dendritic cell (DC) combined with intravenous pembrolizumab for advanced NSCLC $11,815,315
Basic Biology III Shuo Lin Etsrp/ER71 mediated stem cell differentiation into vascular lineage $1,378,781
Tools and Technologies III Carla Koehler A small molecule tool for reducing the malignant potential in reprogramming human iPSCs and ESCs $1,283,900
Quest - Discovery Stage Research Projects April Pyle CRISPR/Cas9 nanoparticle enabled therapy for Duchenne Muscular Dystrophy in muscle stem cells $2,150,400
Comprehensive Grant Zack Jerome Human Embryonic Stem Cell Therapeutic Strategies to Target HIV Disease $2,401,903
Early Translational IV Donald Kohn Beta-Globin Gene Correction of Sickle Cell Disease in Hematopoietic Stem Cells $1,652,076
Basic Biology II Yong Kim Novel Mechanism in Self-Renewal/Differentiation of Human Embryonic Stem Cells $1,259,371
Inception - Discovery Stage Research Projects Alireza Moshaverinia Gingival mesenchymal stem cells as a novel treatment modality for periodontal tissue regeneration $194,483
Tools and Technologies II Martin Martin Pluripotent and Somatic Stem Cell Models to Study Inherited Diarrheal Disorders $1,783,250
Shared Labs Scott Waugh CIRM Shared Research Laboratories $2,000,000
SEED Grant Zoran Galic Genetic Enhancement of the Immune Response to Melanoma via hESC-derived T cells $616,800
Basic Biology IV Owen Witte Trop2 dependent and independent mechanisms of self-renewal in human cancer stem cells $1,254,960
Inception - Discovery Stage Research Projects Stanley Carmichael iPS-Interneuron Transplantation for Neural Repair after Stroke $229,396
Conference Martina Wiedau-Pazos California ALS Summit 2011 $13,300
New Faculty I Dana Jones Characterization of mechanisms regulating de-differentiation and the re-acquisition of stem cell identity $382,773
Basic Biology V Denis Evseenko Promoting survival and countering hypertrophy of pluripotent stem cell (PSC)-derived chondrocytes $411,330
Disease Team Research I Irvin Chen HPSC based therapy for HIV disease using RNAi to CCR5. $9,905,604
Quest - Discovery Stage Research Projects Lili Yang Preclinical Development of An HSC-Engineered Off-The-Shelf iNKT Cell Therapy for Cancer $1,404,000
Research Training II Kenneth Dorshkind UCLA CIRM Research Training Program II $7,790,488
Early Translational II Leif Havton Repair of Conus Medullaris/Cauda Equina Injury using Human ES Cell-Derived Motor Neurons $75,628
Clinical Trial Stage Projects Donald Kohn Efficacy and safety of cryopreserved autologous CD34+ HSC transduced with EFS lentiviral vector encoding for human ADA gene in ADA-SCID subjects $10,056,424
Comprehensive Grant Guoping Fan Epigenetic gene regulation during the differentiation of human embryonic stem cells: Impact on neural repair $2,412,995
Early Translational IV Gerald Lipshutz Gene therapy-corrected autologous hepatocyte-like cells from induced pluripotent stem cells for the treatment of pediatric single enzyme disorders $1,801,629
Basic Biology II Benhur Lee The EphrinB2/EphB4 axis in regulating hESC pluripotency and differentiation $1,371,936
Quest - Discovery Stage Research Projects April Pyle Identification and Generation of Long Term Repopulating Human Muscle Stem Cells from Human Pluripotent Stem Cells $2,184,000
Basic Biology III Gay Crooks Forming the Hematopoietic Niche from Human Pluripotent Stem Cells $1,252,857
Early Translational II Sophie Deng Regeneration of Functional Human Corneal Epithelial Progenitor Cells $697,507
SEED Grant Michael Teitell Role of Mitochondria in Self-Renewal Versus Differentiation of Human Embryonic Stem Cells $543,274
New Faculty Physician Scientist Ali Nsair Human Induced Pluripotent Stem Cell-Derived Cardiovascular Progenitor Cells for Cardiac Cell Therapy. $2,316,894
Inception - Discovery Stage Research Projects Arjun Deb Targeting progenitors in scar tissue to reduce chronic scar burden $230,400
Patent Assistance Fund Awards Adele Rennie Patent Assistance Fund - UCLA $84,973
New Faculty I Siavash Kurdistani Epigenetics in cancer stem cell initiation and clinical outcome prediction $3,063,450
Basic Biology V Bennett Novitch In vitro modeling of human motor neuron disease $1,148,758
Basic Biology I Robb Maclellan Human Cardiovascular Progenitors, their Niches and Control of Self-renewal and Cell Fate $917,667
New Cell Lines Zack Jerome Generation of clinical grade human iPS cells $1,341,000
Disease Team Therapy Planning I Antoni Ribas Genetic Re-programming of Stem Cells to Fight Cancer $97,785
Tools and Technologies III Leif Havton Development of a Relevant Pre-Clinical Animal Model as a Tool to Evaluate Human Stem Cell-Derived Replacement Therapies for Motor Neuron Injuries and Degenerative Diseases $1,308,711
Quest - Discovery Stage Research Projects John Chute Protein tyrosine phosphatase - sigma inhibitors for hematopoietic regeneration $2,116,708
Early Translational I Gabriel Travis Development of a Stem Cell-based Transplantation Strategy for Treating Age-related Macular Degeneration $5,487,136
Early Translational from Disease Team Conversion Stanley Nelson Combination therapy to Enhance Antisense Mediated Exon Skipping for Duchenne Muscular Dystrophy $1,823,545
Early Translational II Noriyuki Kasahara Stem cell-based carriers for RCR vector delivery to glioblastoma $3,340,625
Quest - Discovery Stage Research Projects Stanley Carmichael iPS Glial Therapy for White Matter Stroke and Vascular Dementia $2,096,095
Basic Biology III Yi Sun Studying neurotransmission of normal and diseased human ES cell-derived neurons in vivo $1,382,400
SEED Grant Hanna Mikkola Improving microenvironments to promote hematopoietic stem cell development from human embryonic stem cells $550,241
SEED Grant William Lowry Modeling Human Embryonic Development with Human Embryonic Stem Cells $528,096
New Faculty Physician Scientist Reza Ardehali Preclinical evaluation of human embryonic stem cell-derived cardiovascular progenitors in a large animal model $2,930,388
Inception - Discovery Stage Research Projects Bennett Novitch Organoid Modeling of Human Cortical Microcircuits $209,160
Quest - Discovery Stage Research Projects Caroline Kuo Targeted Gene Editing in the Treatment of X-Linked Hyper-IgM Syndrome $1,512,333
New Faculty I Hanna Mikkola Mechanisms of Hematopoietic stem cell Specification and Self-Renewal $2,286,900
Basic Biology V Samantha Butler Assessing the mechanism by which the Bone Morphogenetic Proteins direct stem cell fate $515,730
Basic Biology I Luisa Iruela-Arispe Molecular Characterization and Functional Exploration of Hemogenic Endothelium $1,371,477
New Cell Lines Amander Clark Generation of Pluripotent Cell Lines from Human Embryos $1,168,501
Disease Team Therapy Planning I Stanley Nelson Combination therapy to Enhance Antisense Mediated Exon Skipping for Duchenne Muscular Dystrophy $68,947
Clinical Trial Stage Projects Donald Kohn A Phase I/II, Non Randomized, Multicenter, Open-Label Study of G1XCGD (Lentiviral Vector Transduced CD34+ Cells) in Patients With X-Linked Chronic Granulomatous Disease $7,083,364
Late Stage Preclinical Projects Sophie Deng Regeneration of a Normal Corneal Surface by Limbal Stem Cell Therapy $4,244,211
Shared Labs Owen Witte CIRM Shared Research Laboratories $1,751,297
Early Translational from Disease Team Conversion Irvin Chen Development of a humanized mouse model for testing anti-HIV HSPC gene therapy strategies in HIV-1 infected mice. $1,505,000
Early Translational II Sophie Deng Regeneration of Functional Human Corneal Epithelial Progenitor Cells $1,524,947
Quest - Discovery Stage Research Projects Scott Kitchen Engineering Lifelong Cellular Immunity to HIV $1,701,178
Basic Biology III Ali Nsair Characterization and Engineering of the Cardiac Stem Cell Niche $1,127,741
Alpha Stem Cell Clinics John Adams UCLA-UCI Alpha Stem Cell Clinic (ASCC) Consortium $8,000,000
Inception - Discovery Stage Research Projects April Pyle Novel Platforms to Enhance In Vivo Delivery of Skeletal Muscle Progenitor Cells from Human Pluripotent Stem Cells $230,400
New Faculty II Antoni Ribas Stem Cells for Immune System Regeneration to Fight Cancer $3,072,000
Tissue Collection for Disease Modeling Brigitte Gomperts Using human induced pluripotent stem cells to improve our understanding of Idiopathic Pulmonary Fibrosis $811,231
Quest - Discovery Stage Research Projects Gay Crooks Platform Technology for Pluripotent Stem Cell-Derived T cell Immunotherapy $965,636
New Faculty I Kathrin Plath In vitro reprogramming of mouse and human somatic cells to an embryonic state $2,229,427
Major Facilities Gene Block UCLA CIRM Institute $19,854,900
Basic Biology I Bennett Novitch Molecular Characterization of hESC and hIPSC-Derived Spinal Motor Neurons $1,229,922
Total:
$287,532,302.00
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