University of California Los Angeles

Cells derived from embryonic stem cells, iPS cells appear immature

A trend over the past few years has been comparing embryonic stem cells, adult stem cells and reprogrammed adult cells (also known as iPS cells) to each other and to other cell types. The goal is to understand what the cells are, exactly, and and how they differ from each other. Eventually this information could help researchers learn which type of cell will be most effective for developing therapies, understanding diseases or drug screening.

Heart cells divide again?

One perplexing question in regenerative medicine is why the human heart muscle cells are unable to divide and multiply their numbers. If they could, maybe they'd be able to produce new heart cells to replace those lost after a heart attack. Newts and salamanders can do it, why can't we?

Origin of lung mucus glands found, insights for cystic fibrosis, asthma

Last week's big news at CIRM was the election of Jonathan Thomas as the new governing board chair, as we announced late Wednesday night. He will be replacing Robert Klein, who has served the agency since its inception in 2004. Not that anyone can replace Klein, exactly, but Thomas seems eager to step in and start leading the agency.

California/Scottish collaboration to heal bones

The good folks at the Scottish Stem Cell Network have pointed out an interesting relationship between CIRM and Scotland. We don't have a formal funding relationship with Scotland (you can read about our collaborative funding agreements here) but we do have a researcher with a foot in both countries.

New disease-specific embryonic stem cell lines from Michigan

Stem cell scientists at the University of Michigan and in Detroit have created two embryonic stem cell lines that contain disease-causing mutations: Hemophilia B, a hereditary condition in which the blood does not clot properly and Charcot-Marie-Tooth disease, an inherited disorder leading to degeneration of muscles in the foot, lower leg and hand.

Stem cell therapy treats HIV, basis for two CIRM disease teams

There's a lot of buzz today over a paper in the journal Blood declaring a man who has come to be known as the "Berlin patient" cured of HIV.

Protein Linked to Normal Prostate Stem Cells and to Cancer

When I was the editor of a national magazine for physicians, I told my writers to do any story they found on prostate issues, with our overwhelming male audience then, I knew those stories would get high readership scores. My readers back then would have loved today's news out of UCLA. The team there, led by CIRM grantee Owen Witte, found that the inhibition of a certain protein slowed the growth of an aggressive form of prostate cancer in animal models.

HIV/AIDS video for World AIDS Day

World AIDS Day seems like a good time to revisit a video we made this year featuring CIRM board member Jeff Sheehy, who is a long-time advocate for HIV/AIDS research:

15 registered stem cell lines and counting

Guest blogger Geoff Lomax
Senior Officer to the Standards Working Group

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