University of California, Los Angeles

Total Awards: 
70
Approved funds: 
$208,332,072
Institution type: 
Not for profit

Awards to the Institution

Funding
Early Translational IV: Robert Reiter Clinical Development of an N-cadherin Antibody to Target Cancer Stem Cells $4,075,668
New Faculty I: Siavash Kurdistani Epigenetics in cancer stem cell initiation and clinical outcome prediction $3,238,450
Tools and Technologies II: Richard Gatti Use of hiPSCs to develop lead compounds for the treatment of genetic diseases $1,833,054
Basic Biology V: Thomas Otis In vitro modeling of human motor neuron disease $1,148,758
Disease Team Therapy Development - Research: Antoni Ribas Genetic Re-programming of Stem Cells to Fight Cancer $19,999,563
Basic Biology V: Samantha Butler Assessing the mechanism by which the Bone Morphogenetic Proteins direct stem cell fate $598,367
Basic Biology IV: Kathrin Plath Understanding the status of the X chromosomes in human ESCs and preimplantation embryos $1,382,400
Early Translational II: Sophie Deng Regeneration of Functional Human Corneal Epithelial Progenitor Cells $1,654,058
Basic Biology II: Douglas Black Programs of alternative splicing regulation by polypyrimidine tract binding protein $1,350,994
Basic Biology II: Yong Kim Novel Mechanism in Self-Renewal/Differentiation of Human Embryonic Stem Cells $1,259,371
Basic Biology II: Benhur Lee The EphrinB2/EphB4 axis in regulating hESC pluripotency and differentiation $1,371,936
Early Translational I: Gabriel Travis Development of a Stem Cell-based Transplantation Strategy for Treating Age-related Macular Degeneration $5,503,069
Early Translational II: Noriyuki Kasahara Stem cell-based carriers for RCR vector delivery to glioblastoma $3,370,607
Early Translational II: Bruno Peault Harnessing native fat-residing stem cells for bone regeneration $5,391,560
Basic Biology IV: Owen Witte Trop2 dependent and independent mechanisms of self-renewal in human cancer stem cells $1,382,400
Comprehensive Grant: Gay Crooks Regulated Expansion of Lympho-hematopoietic Stem and Progenitor Cells from Human Embryonic Stem Cells (hESC) $2,551,088
Comprehensive Grant: Zack Jerome Human Embryonic Stem Cell Therapeutic Strategies to Target HIV Disease $2,516,831
Comprehensive Grant: Guoping Fan Epigenetic gene regulation during the differentiation of human embryonic stem cells: Impact on neural repair $2,516,613
New Faculty I: Dana Jones Characterization of mechanisms regulating de-differentiation and the re-acquisition of stem cell identity $2,675,234
New Faculty I: Hanna Mikkola Mechanisms of Hematopoietic stem cell Specification and Self-Renewal $2,286,900
New Faculty I: Kathrin Plath In vitro reprogramming of mouse and human somatic cells to an embryonic state $2,229,427
Disease Team Planning: Irvin Chen Stem Cell Therapy for AIDS- Disease Team Planning $52,500
SEED Grant: Michael Teitell Role of Mitochondria in Self-Renewal Versus Differentiation of Human Embryonic Stem Cells $635,024
Tools and Technologies II: Stanley Carmichael Development of a Hydrogel Matrix for Stem Cell Growth and Neural Repair after Stroke $1,825,613
New Faculty Physician Scientist: Ali Nsair Human Induced Pluripotent Stem Cell-Derived Cardiovascular Progenitor Cells for Cardiac Cell Therapy. $3,179,315
Disease Team Planning: Stanley Carmichael Development of a Stem Cell Therapy to Promote Functional Recovery in Stroke $44,792
SEED Grant: William Lowry Modeling Human Embryonic Development with Human Embryonic Stem Cells $571,575
New Faculty Physician Scientist: Reza Ardehali Preclinical evaluation of human embryonic stem cell-derived cardiovascular progenitors $3,105,388
New Faculty II: Antoni Ribas Stem Cells for Immune System Regeneration to Fight Cancer $3,247,000
Tools and Technologies II: Martin Martin Pluripotent and Somatic Stem Cell Models to Study Inherited Diarrheal Disorders $1,783,250
Tissue Collection for Disease Modeling: Brigitte Gomperts Using human induced pluripotent stem cells to improve our understanding of Idiopathic Pulmonary Fibrosis $934,515
New Faculty II: Brigitte Gomperts Stem Cells in Lung Cancer $2,556,572
Basic Biology III: Gay Crooks Forming the Hematopoietic Niche from Human Pluripotent Stem Cells $1,375,983
Basic Biology III: Yi Sun Studying neurotransmission of normal and diseased human ES cell-derived neurons in vivo $1,382,400
Early Translational IV: Zack Jerome Stem Cell Programming With Chimeric Antigen Receptors to Eradicate HIV Infection $5,303,375
Basic Biology III: Ali Nsair Characterization and Engineering of the Cardiac Stem Cell Niche $1,181,306
Early Translational IV: Donald Kohn Beta-Globin Gene Correction of Sickle Cell Disease in Hematopoietic Stem Cells $1,815,308
Disease Team Research I: Dennis Slamon THERAPEUTIC OPPORTUNITIES TO TARGET TUMOR INITIATING CELLS IN SOLID TUMORS $19,979,660
Basic Biology III: Kathrin Plath Discovery of mechanisms that control epigenetic states in human reprogramming and pluripotent cells $1,364,598
Early Translational IV: Gerald Lipshutz Gene therapy-corrected autologous hepatocyte-like cells from induced pluripotent stem cells for the treatment of pediatric single enzyme disorders $1,801,629
Disease Team Research I: Donald Kohn Stem Cell Gene Therapy for Sickle Cell Disease $9,212,365
Basic Biology III: William Lowry Molecular determinants of accurate differentiation from human pluripotent stem cells $1,354,230
Early Translational from Disease Team Conversion: Stanley Nelson Combination therapy to Enhance Antisense Mediated Exon Skipping for Duchenne Muscular Dystrophy $0
Disease Team Research I: Irvin Chen HPSC based therapy for HIV disease using RNAi to CCR5. $9,905,604
Shared Labs: Owen Witte CIRM Shared Research Laboratories $3,751,297
Basic Biology III: Shuo Lin Etsrp/ER71 mediated stem cell differentiation into vascular lineage $1,382,400
Early Translational from Disease Team Conversion: Irvin Chen HPSC based therapy for HIV disease using RNAi to CCR5. $1,505,000
New Cell Lines: Zack Jerome Generation of clinical grade human iPS cells $1,382,400
Tools and Technologies I: Hsian-Rong Tseng Microfluidic Platform for Screening Chemically Defined Conditions that Facilitate Clonal Expansion of Human Pluripotent Stem Cells $914,096
Research Training II: Kenneth Dorshkind CIRM Research Training Program II $7,982,293
Disease Team Therapy Development III: Donald Kohn Clinical Trial of Stem Cell Gene Therapy for Sickle Cell Disease $13,935,441
New Cell Lines: Amander Clark Generation of Pluripotent Cell Lines from Human Embryos $1,177,648
Tools and Technologies I: Michael Phelps Novel Tools and Technologies for Translational PET Imaging of Cell-based Therapies $914,096
Disease Team Therapy Planning I: Antoni Ribas Genetic Re-programming of Stem Cells to Fight Cancer $110,000
Disease Team Therapy Development III: Dennis Slamon A Phase I dose escalation and expansion clinical trial in patients with advanced solid tumors $6,924,317
SEED Grant: Irvin Chen Genetic modification of the human genome to resist HIV-1 infection and/or disease progression $642,652
Transplantation Immunology: Gay Crooks Engineering Thymic Regeneration to Induce Tolerance $1,357,398
Disease Team Therapy Planning I: Stanley Nelson Combination therapy to Enhance Antisense Mediated Exon Skipping for Duchenne Muscular Dystrophy $86,414
Basic Biology V: Lili Yang Differentiation of Human Hematopoietic Stem Cells into iNKT Cells $614,400
Basic Biology I: Robb Maclellan Human Cardiovascular Progenitors, their Niches and Control of Self-renewal and Cell Fate $1,378,076
SEED Grant: Siavash Kurdistani Cellular epigenetic diversity as a blueprint for defining the identity and functional potential of human embryonic stem cells $641,047
Training Grant I-1: Owen Witte CIRM Type I Comprehensive Training Program $3,750,000
Basic Biology V: Denis Evseenko Promoting survival and countering hypertrophy of pluripotent stem cell (PSC)-derived chondrocytes $1,146,468
Basic Biology I: Luisa Iruela-Arispe Molecular Characterization and Functional Exploration of Hemogenic Endothelium $1,371,477
SEED Grant: Noriyuki Kasahara Down-Regulation of Alloreactive Immune Responses to hES Cell-Derived Graft Tissues $469,219
Basic Biology I: Bennett Novitch Molecular Characterization of hESC and hIPSC-Derived Spinal Motor Neurons $1,363,262
SEED Grant: Zoran Galic Genetic Enhancement of the Immune Response to Melanoma via hESC-derived T cells $642,501
Major Facilities: Gene Block No Title $19,854,900
Basic Biology I: Michael Teitell Mitochondrial Metabolism in hESC and hiPSC Differentiation, Reprogramming, and Cancer $1,323,029
SEED Grant: Hanna Mikkola Improving microenvironments to promote hematopoietic stem cell development from human embryonic stem cells $577,037
Total:
$216,145,218.00
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© 2013 California Institute for Regenerative Medicine