Active Awards Portfolio Dashboard

It takes a lot of effort to develop a promising stem cell research idea into an effective treatment that can help patients. CIRM funds a pipeline of projects spanning discovery, translation and clinical stage research. Check out our portfolio of active research awards in our interactive dashboard below. For a detailed list of CIRM-funded clinical trials, visit our Clinical Trials Dashboard.

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Disease

Therapeutic or Technology

Disease	Cell Type	Therapeutic or Technology	Institution	Project Objective
Leukemia, Acute Myeloid (AML)	Cancer Stem Cell	Gene-modified, personalized cell therapy	UCSF	IND
Neurological Disorders	Adult Stem Cell	Gene-modified, personalized cell therapy	UC Davis	IND
B cell cancers, Solid Tumors	Cancer Stem Cell	Biologic	Nammi Therapeutics, Inc.	IND
B cell cancers	Somatic Cell	Gene-modified, donor cell therapy	Angiocrine	Clinical Trial, Phase 3
Immune Disease	Adult Stem Cell	Donor cell therapy	Ossium Health	IND
Parkinson's Disease	iPS Cell	Donor cell therapy	Ryne Bio	IND
Bone or Cartilage Disease, Hearing Loss, Intellectual Disability, Metabolic Disorders, Vision Loss	Somatic Cell	Personalized cell therapy	Immusoft Corporation	Clinical Trial, Phase 1 or Phase 1/2
Spinal Cord Injury	Embryonic Stem Cell, iPS Cell	Gene-modified, personalized cell therapy	BrainXell Therapeutics	Development Candidate, Proof of Concept
Heart failure	iPS Cell	Gene Therapy, cell free	UC Berkeley	Development Candidate, Proof of Concept
Neurological Disorders, Sanfilippo Syndrome/MPS III	Embryonic Stem Cell	Gene-modified, donor cell therapy	Lundquist Institute	Development Candidate, Proof of Concept
Intervertebral disc degeneration	iPS Cell	Donor cell therapy	Cedars-Sinai	Proof of Concept
Tendon/Ligament/Connective Tissue Injury or Disorder	Embryonic Stem Cell	Biologic	Scripps Health	Development Candidate, Proof of Concept
Brain Cancer	Cancer Stem Cell	Small molecule therapy	UCLA	Development Candidate
Autism, Intellectual Disability, Metabolic Disorders	iPS Cell	Gene Therapy, cell free	UCLA	Development Candidate, Proof of Concept
Lung Disease, Fibrosis	Adult Stem Cell	Small molecule therapy	Rubedo Life Sciences Inc.	Development Candidate, Proof of Concept
Duchenne Muscular Dystrophy	Other, Somatic Cell	Gene Therapy, cell free	UC Davis	Proof of Concept
			UC Berkeley
			Greenstone Biosciences
Breast Cancer	Adult Stem Cell	Small molecule therapy	UCLA	Development Candidate, Proof of Concept
			UCLA
Spinal Cord Injury	Embryonic Stem Cell, iPS Cell	Donor cell therapy	Gladstone	Development Candidate, Proof of Concept
			COH
Metabolic Disorders	Adult Stem Cell	Gene-modified, personalized cell therapy	Rampart Bioscience	IND
Osteoarthritis	Somatic Cell	Gene Therapy, cell free	Genascence Corporation	Clinical Trial, Phase 1 or Phase 1/2

California's Stem Cell Agency

California Institute for Regenerative Medicine

Active Awards Portfolio Dashboard

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aa Multiple Diseases (Centers & Resoures)
Aging
– Arthritis
Blood Disorders
– Alpha Thalassemia Major
– Anemia
– Beta Thalassemia
– Bone Marrow Transplant and Viral Infection
– Hemophilia A
– Hyper IgM Syndrome
– IPEX Syndrome
– Leukocyte Adhesion Deficiency
– Severe Combined Immunodeficiency, Adenosine deaminase-deficient (ADA-SCID)
– Severe Combined Immunodeficiency, Artemis deficient (ART-SCID)
– Severe Combined Immunodeficiency, X-linked (X-SCID)
– Sickle Cell Disease
– X-linked Chronic Granulomatous Disease
Bone or Cartilage Disease
– Cartilage defect
– Intervertebral disc degeneration
– Osteoarthritis
– Osteonecrosis
– Osteoporosis, malignant infantile
– Tendon/Ligament/Connective Tissue Injury or Disorder
Cancer
– Blood Cancer
–– Acute Myeloid Leukemia
–– B cell cancers
–– HIV-related Lymphoma
–– Leukemia
–– Leukemia, Acute Myeloid (AML)
–– Multiple Myeloma
– Solid Tumors
–– Brain Cancer
–– Breast Cancer
–– Colon Cancer
–– Lung Cancer
–– Melanoma
–– Ovarian Cancer
–– Pancreatic Cancer
–– Prostate Cancer
–– Sarcoma
–– Skin cancer
Developmental Disorders
Fertility
Genetic Disorder
Hearing Loss
Heart Disease
– Heart disease associated with Duchenne muscular dystrophy
– Heart failure
– Pulmonary Hypertension
–– Hypertension, pulmonary arterial
Immune Disease
– Thymic Disorder, 22q11 Deletion/DiGeorge
Incontinence
Infectious Disease
– COVID-19
– HIV/AIDS
– Zika virus
Kidney Disease
– Kidney Failure
Metabolic Disorders
– Cystinosis
– Danon Disease
– Diabetes
–– Diabetic Wounds
–– Type 1 diabetes
– Intestinal Disease
–– Inflammatory bowel disease
– Liver Disease
– Sanfilippo Syndrome/MPS III
Multiple Indications (Alpha Clinics)
Neurological Disorders
– Alzheimer's Disease
– Amyotrophic Lateral Sclerosis
– Angelman Syndrome
– Autism
– Brain Injury, hypoxic, ischemic
– Canavan Disease
– Dementia
– Epilepsy
– Huntington's Disease
– Intellectual Disability
– Multiple Sclerosis
– Neuropathy
– Parkinson's Disease
– Rett's Syndrome
– Spina Bifida
– Spinal Cord Injury
– Spinal Muscular Atrophy
– Stroke
– Traumatic Brain Injury
Other
Pediatrics
Respiratory Disorders
– Cystic Fibrosis
– Lung Disease, Fibrosis
Skeletal/Smooth Muscle disorders
– Bladder or Urinary Tract Disorder
– Duchenne Muscular Dystrophy
– Muscle Injury
– Muscular Dystrophy
Skin Disease
– Epidermolysis Bullosa
– Wounds, ulcers
Toxicity
Trauma
Vascular Disease
Vision Loss
– Age-related macular degeneration
– Corneal Damage
– Retinitis Pigmentosa

Therapeutic Approach
– Biologic
–– Antibody
–– Convalescent Plasma
–– Exosomes based therapy
–– Gene modification
–– Nucleic acid based therapy
–– Protein/peptide therapy
–– Vaccine
– Gene Therapy (All)
–– Gene Therapy, cell free
–– Gene-modified, donor cell therapy
–– Gene-modified, personalized cell therapy
– Small molecule therapy
– Device
– Donor cell therapy
– Personalized cell therapy
– Other Components
Technology
– Assay development
– Cell Line Generation-Resource
– Diagnostic Test
– Gene editing tools
– Cell delivery or targeting
– Cell imaging & tracking
– Cell processing & handling
– Exploring disease mechanisms
– Exploring stem cell mechanisms
– Immune tolerance/management
– Model system development
– Specific Cell Type Derivation
– Therapeutic target discovery
– Tissue engineering