Active Awards Portfolio Dashboard

It takes a lot of effort to develop a promising stem cell research idea into an effective treatment that can help patients. CIRM funds a pipeline of projects spanning discovery, translation and clinical stage research. Check out our portfolio of active research awards in our interactive dashboard below. For a detailed list of CIRM-funded clinical trials, visit our Clinical Trials Dashboard.

Disease | Cell Type | Therapeutic or Technology | Institution | Stage | Project Objective | Details |
---|---|---|---|---|---|---|
Neurological Disorders | iPS Cell | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | UC Davis | ![]() |
Development Candidate, Proof of Concept | |
Vision Loss | Somatic Cell | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | Adverum Biotechnologies | ![]() |
Development Candidate, Proof of Concept | |
Blood Cancer, Cancer, Leukemia, Acute Myeloid (AML) | Adult or Tissue Stem Cell, Somatic Cell | Gene Therapy (All), Gene-modified, donor cell therapy, Immune tolerance/management, Technology, Therapeutic Approach | Stanford | ![]() |
Development Candidate | |
Infectious Disease, Neurological Disorders | iPS Cell | Gene editing tools, Gene Therapy (All), Gene-modified, donor cell therapy, Immune tolerance/management, Technology, Therapeutic Approach | UCSF | ![]() |
Development Candidate, Proof of Concept | |
Breast Cancer, Cancer, Solid Tumors | Cancer Stem Cell | Small molecule therapy, Therapeutic Approach | Stanford | ![]() |
Development Candidate | |
Heart Disease | Adult or Tissue Stem Cell | Gene Therapy (All), Gene Therapy, cell free, Nucleic acid based therapy, Therapeutic Approach | Cedars-Sinai | ![]() |
Development Candidate, Proof of Concept | |
Liver Disease, Metabolic Disorders | Embryonic Stem Cell | Donor cell therapy, Therapeutic Approach | USC | ![]() |
Development Candidate, Proof of Concept | |
Cancer, Prostate Cancer, Solid Tumors | iPS Cell | Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach | COH | ![]() |
Development Candidate, Proof of Concept | |
Neurological Disorders, Spinal Cord Injury | Embryonic Stem Cell, iPS Cell | Donor cell therapy, Therapeutic Approach | Gladstone | ![]() |
Development Candidate, Proof of Concept | |
Cancer, Melanoma, Solid Tumors | Adult or Tissue Stem Cell | Biologic, Small molecule therapy, Therapeutic Approach, Vaccine | UCLA | ![]() |
Proof of Concept | |
Breast Cancer, Cancer, Solid Tumors | Adult or Tissue Stem Cell, Cancer Stem Cell | Small molecule therapy, Therapeutic Approach | UCLA | ![]() |
Development Candidate, Proof of Concept | |
Duchenne Muscular Dystrophy, Genetic Disorder, Skeletal/Smooth Muscle disorders | iPS Cell | Model system development, Technology | Greenstone Biosciences | ![]() |
Tool/Resources/Bottleneck | |
Blood Disorders, Severe Combined Immunodeficiency, Artemis deficient (ART-SCID) | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UC Berkeley | ![]() |
Development Candidate | |
Duchenne Muscular Dystrophy, Skeletal/Smooth Muscle disorders | Other, Somatic Cell | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | UC Davis | ![]() |
Proof of Concept | |
Lung Disease, Fibrosis, Respiratory Disorders | Adult or Tissue Stem Cell | Small molecule therapy, Therapeutic Approach | Rubedo Life Sciences Inc. | ![]() |
Development Candidate, Proof of Concept | |
Autism, Intellectual Disability, Metabolic Disorders, Neurological Disorders | iPS Cell | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | UCLA | ![]() |
Development Candidate, Proof of Concept | |
Brain Cancer, Cancer, Solid Tumors | Cancer Stem Cell | Small molecule therapy, Therapeutic Approach | UCLA | ![]() |
Development Candidate | |
Bone or Cartilage Disease, Tendon/Ligament/Connective Tissue Injury or Disorder | Embryonic Stem Cell | Donor cell therapy, Other Components, Therapeutic Approach | Scripps Health | ![]() |
Development Candidate, Proof of Concept | |
Bone or Cartilage Disease, Intervertebral disc degeneration | iPS Cell | Donor cell therapy, Other Components, Therapeutic Approach | Cedars-Sinai | ![]() |
Development Candidate, Proof of Concept | |
Metabolic Disorders, Neurological Disorders, Sanfilippo Syndrome/MPS III | Embryonic Stem Cell | Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach | Lundquist Institute | ![]() |
Development Candidate, Proof of Concept | |
Heart Disease, Heart failure | iPS Cell | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | UC Berkeley | ![]() |
Development Candidate, Proof of Concept | |
Neurological Disorders, Spinal Cord Injury | Embryonic Stem Cell, iPS Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | BrainXell Therapeutics | ![]() |
Development Candidate, Proof of Concept | |
Autism, Neurological Disorders | iPS Cell | Donor cell therapy, Therapeutic Approach | UCSD | ![]() |
Development Candidate, Proof of Concept | |
Heart Disease, Heart failure | iPS Cell | Gene Therapy (All), Gene Therapy, cell free, Nucleic acid based therapy, Therapeutic Approach | Gladstone | ![]() |
Development Candidate, Proof of Concept | |
HIV/AIDS, Infectious Disease | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | Scintillon Inst | ![]() |
Development Candidate, Proof of Concept | |
Cancer, Solid Tumors | Somatic Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UC Irvine | ![]() |
Development Candidate | |
Cancer, Ovarian Cancer, Solid Tumors | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach | UCLA | ![]() |
Development Candidate | |
Diabetes, Metabolic Disorders, Type 1 diabetes | Embryonic Stem Cell, iPS Cell | Cell imaging & tracking, Donor cell therapy, Technology, Therapeutic Approach | Minutia, Inc. | ![]() |
Development Candidate, Proof of Concept | |
iPS Cell | Model system development, Specific Cell Type Derivation, Technology | Nanotools Bioscience | ![]() |
Proof of Concept | ||
Vision Loss | Embryonic Stem Cell, iPS Cell | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | UCLA | ![]() |
Development Candidate, Proof of Concept | |
Autism, Epilepsy, Neurological Disorders, Other | iPS Cell | Gene Therapy (All), Gene Therapy, cell free, Nucleic acid based therapy, Therapeutic Approach | UCSD | ![]() |
Development Candidate, Proof of Concept | |
Alzheimer's Disease, Neurological Disorders, Parkinson's Disease | iPS Cell | Small molecule therapy, Therapeutic Approach | Scripps Research | ![]() |
Development Candidate, Proof of Concept | |
Blood Cancer, Cancer, Leukemia | Cancer Stem Cell | Small molecule therapy, Therapeutic Approach | UCLA | ![]() |
Development Candidate | |
Cancer, Pancreatic Cancer, Solid Tumors | Cancer Stem Cell | Antibody, Biologic, Therapeutic Approach | UCSD | ![]() |
Development Candidate | |
Intestinal Disease, Metabolic Disorders | iPS Cell | Exploring disease mechanisms, Model system development, Technology | Cedars-Sinai | ![]() |
Proof of Concept, Tool/Resources/Bottleneck | |
Blood Disorders | Adult or Tissue Stem Cell | Small molecule therapy, Therapeutic Approach | Scripps Research | ![]() |
Development Candidate, Proof of Concept | |
Epilepsy, Neurological Disorders, Other | iPS Cell | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | UC Davis | ![]() |
Development Candidate, Proof of Concept | |
Blood Disorders | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UCLA | ![]() |
Development Candidate, Proof of Concept | |
Alpha Thalassemia Major, Blood Disorders | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UCLA | ![]() |
Development Candidate | |
Blood Disorders | Adult or Tissue Stem Cell | Antibody, Biologic, Therapeutic Approach | Stanford | ![]() |
Development Candidate | |
Heart Disease, Heart failure | Somatic Cell | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | Tenaya Therapeutics, Inc. | ![]() |
Development Candidate | |
Cancer, Other, Skin Disease, Wounds, ulcers | Adult or Tissue Stem Cell | Biologic, Protein/peptide therapy, Therapeutic Approach | Intact Therapeutics, Inc. | ![]() |
Development Candidate, Proof of Concept | |
Breast Cancer, Cancer, Solid Tumors | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach | Cytonus Therapeutics, Inc. | ![]() |
Development Candidate, Proof of Concept | |
Cancer, Sarcoma, Solid Tumors | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | Stanford | ![]() |
Development Candidate, Proof of Concept | |
Skeletal/Smooth Muscle disorders | Embryonic Stem Cell, iPS Cell | Biologic, Exosomes based therapy, Therapeutic Approach | Stanford | ![]() |
Development Candidate, Proof of Concept | |
Muscle Injury, Skeletal/Smooth Muscle disorders | Adult or Tissue Stem Cell | Other Components, Personalized cell therapy, Therapeutic Approach | UCSF | ![]() |
Development Candidate, Proof of Concept | |
Bone or Cartilage Disease, Cartilage defect, Osteoarthritis | Embryonic Stem Cell | Donor cell therapy, Other Components, Therapeutic Approach | Scripps Health | ![]() |
Development Candidate, Proof of Concept | |
Bone or Cartilage Disease, Cartilage defect | Adult or Tissue Stem Cell | Other Components, Personalized cell therapy, Therapeutic Approach | The Stone Research Foundation for Sports Medicine and Arthritis | ![]() |
Development Candidate, Proof of Concept | |
Kidney Disease | Somatic Cell | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | UCSF | ![]() |
Development Candidate, Proof of Concept | |
Neurological Disorders, Spinal Cord Injury | iPS Cell | Other Components, Personalized cell therapy, Therapeutic Approach | Stanford | ![]() |
Development Candidate, Proof of Concept |