Active Awards Portfolio Dashboard

It takes a lot of effort to develop a promising stem cell research idea into an effective treatment that can help patients. CIRM funds a pipeline of projects spanning discovery, translation and clinical stage research. Check out our portfolio of active research awards in our interactive dashboard below. For a detailed list of CIRM-funded clinical trials, visit our Clinical Trials Dashboard.

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Disease	Cell Type	Therapeutic or Technology	Institution	Project Objective
Angelman Syndrome, Neurological Disorders, Pediatrics	Adult or Tissue Stem Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	UC Davis	IND
Vision Loss			Blue Gen Therapeutics Foundation
Heart Disease		Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach	Rejuvenate Bio	IND
Neurological Disorders		Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach	Amplo Biotechnology Inc	IND
Neurological Disorders, Spinal Cord Injury	Embryonic Stem Cell	Donor cell therapy, Therapeutic Approach	UCSD	IND
Heart Disease, Heart failure		Antibody, Biologic, Therapeutic Approach	UCLA	IND
Cancer, Sarcoma, Solid Tumors	Adult or Tissue Stem Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	CHLA	IND
Blood Cancer, Cancer, Multiple Myeloma	Adult or Tissue Stem Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	UCSF	IND
Developmental Disorders, Genetic Disorder, Neurological Disorders, Pediatrics		Gene Therapy (All), Gene Therapy, cell free, Nucleic acid based therapy, Therapeutic Approach	Elpida Therapeutics	IND
Heart Disease, Heart failure	Adult or Tissue Stem Cell, Somatic Cell	Biologic, Exosomes based therapy, Therapeutic Approach	Cedars-Sinai	IND
Cancer, Ovarian Cancer, Solid Tumors	Adult or Tissue Stem Cell	Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach	COH	IND
Epilepsy, Intellectual Disability, Neurological Disorders		Gene Therapy (All), Gene Therapy, cell free, Nucleic acid based therapy, Therapeutic Approach	Mahzi Therapeutics	IND
Blood Disorders, Sickle Cell Disease	Adult or Tissue Stem Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	UC Davis	IND
Bone or Cartilage Disease, Cartilage defect	Somatic Cell	Donor cell therapy, Therapeutic Approach	UC Irvine	IND
Cystic Fibrosis, Respiratory Disorders	Adult or Tissue Stem Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	Stanford	IND
Age-related macular degeneration, Vision Loss	Embryonic Stem Cell	Biologic, Therapeutic Approach	USC	IND
Blood Cancer, Cancer, Leukemia, Acute Myeloid (AML)		Small molecule therapy, Therapeutic Approach	Aspera Biomedicines, Inc.	IND
Age-related macular degeneration, Vision Loss	iPS Cell	Personalized cell therapy, Therapeutic Approach	UCLA	IND
Genetic Disorder, Metabolic Disorders	Adult or Tissue Stem Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	Rampart Bioscience	IND
Breast Cancer, Cancer, Melanoma, Solid Tumors	Somatic Cell	Donor cell therapy, Therapeutic Approach	Calidi Biotherapeutics, Inc.	IND
Immune Disease	Adult or Tissue Stem Cell	Donor cell therapy, Therapeutic Approach	Ossium Health, Inc.	IND
Neurological Disorders	Adult or Tissue Stem Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Personalized cell therapy, Therapeutic Approach	UC Davis	IND
Genetic Disorder, Metabolic Disorders, Neurological Disorders, Pediatrics	Somatic Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	Stanford	IND
Blood Cancer, Cancer, Leukemia, Acute Myeloid (AML)	Cancer Stem Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	UCSF	IND
Blood Disorders, X-linked Chronic Granulomatous Disease	Adult or Tissue Stem Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	ImmunoVec	Clinical Trial, Phase 1 or Phase 1/2
Skin Disease, Wounds, ulcers		Small molecule therapy, Therapeutic Approach	UCLA	IND
Bone or Cartilage Disease, Cartilage defect	Embryonic Stem Cell	Donor cell therapy, Therapeutic Approach	USC	IND
Huntington's Disease, Neurological Disorders	Embryonic Stem Cell	Donor cell therapy, Therapeutic Approach	UC Irvine	IND
Neurological Disorders, Traumatic Brain Injury	Embryonic Stem Cell	Biologic, Exosomes based therapy, Therapeutic Approach	UC Irvine	Development Candidate, Proof of Concept, Research Insights

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Displaying 201 – 229 of 229

aa Multiple Diseases (Centers & Resoures)
Age-related macular degeneration
Aging
Alpha Thalassemia Major
Alzheimer's Disease
Amyotrophic Lateral Sclerosis
Anemia
Angelman Syndrome
Arthritis
Autism
Autoimmune Disorder
B cell cancers
Beta Thalassemia
Bladder or Urinary Tract Disorder
Blood Cancer
Blood Disorders
Bone Marrow Transplant and Viral Infection
Bone or Cartilage Disease
Brain Cancer
Brain Injury, hypoxic, ischemic
Breast Cancer
Canavan Disease
Cancer
Cartilage defect
Colon Cancer
Corneal Damage
COVID-19
Cystic Fibrosis
Cystinosis
Danon Disease
Dementia
Developmental Disorders
Diabetes
Diabetic Wounds
Duchenne Muscular Dystrophy
Epidermolysis Bullosa
Epilepsy
Fertility
Genetic Disorder
Hearing Loss
Heart Disease
Heart disease associated with Duchenne muscular dystrophy
Heart failure
Hemophilia A
HIV-related Lymphoma
HIV/AIDS
Huntington's Disease
Hyper IgM Syndrome
Hypertension, pulmonary arterial
Immune Disease
Incontinence
Infectious Disease
Inflammatory bowel disease
Intellectual Disability
Intervertebral disc degeneration
Intestinal Disease
IPEX Syndrome
Kidney Disease
Kidney Failure
Leukemia
Leukemia, Acute Myeloid (AML)
Leukocyte Adhesion Deficiency
Liver Disease
Lung Cancer
Lung Disease, Fibrosis
Lupus, Systemic Lupus Erythematosus (SLE)
Melanoma
Metabolic Disorders
Multiple Myeloma
Multiple Sclerosis
Muscle Injury
Muscular Dystrophy
N/A
Neurological Disorders
Neuropathy
Osteoarthritis
Osteonecrosis
Other
Ovarian Cancer
Pancreatic Cancer
Parkinson's Disease
Pediatrics
Prostate Cancer
Pulmonary Hypertension
Respiratory Disorders
Retinitis Pigmentosa
Rett's Syndrome
Sanfilippo Syndrome/MPS III
Sarcoma
Severe Combined Immunodeficiency, Adenosine deaminase-deficient (ADA-SCID)
Severe Combined Immunodeficiency, Artemis deficient (ART-SCID)
Severe Combined Immunodeficiency, X-linked (X-SCID)
Sickle Cell Disease
Skeletal/Smooth Muscle disorders
Skin cancer
Skin Disease
Solid Tumors
Spina Bifida
Spinal Cord Injury
Spinal Muscular Atrophy
Stroke
Tendon/Ligament/Connective Tissue Injury or Disorder
Thymic Disorder, 22q11 Deletion/DiGeorge
Toxicity
Trauma
Traumatic Brain Injury
Type 1 diabetes
Vascular Disease
Vision Loss
Wounds, ulcers
X-linked Chronic Granulomatous Disease
Zika virus

Antibody
Assay development
Bioinformatics/Computational Tools
Biologic
Cell delivery or targeting
Cell imaging & tracking
Cell Line Generation-Resource
Cell processing & handling
Convalescent Plasma
Device
Diagnostic Test
Donor cell therapy
Exosomes based therapy
Exploring disease mechanisms
Exploring stem cell mechanisms
Exploring therapeutic Mechanism
Gene editing tools
Gene modification
Gene Therapy (All)
Gene Therapy, cell free
Gene-modified, donor cell therapy
Gene-modified, personalized cell therapy
Immune tolerance/management
Model system development
N/A
Nucleic acid based therapy
Other Components
Personalized cell therapy
Protein/peptide therapy
Small molecule therapy
Specific Cell Type Derivation
Technology
Therapeutic Approach
Therapeutic target discovery
Tissue engineering
Vaccine

Active Awards Portfolio Dashboard

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