Active Awards Portfolio Dashboard
It takes a lot of effort to develop a promising stem cell research idea into an effective treatment that can help patients. CIRM funds a pipeline of projects spanning discovery, translation and clinical stage research. Check out our portfolio of active research awards in our interactive dashboard below. For a detailed list of CIRM-funded clinical trials, visit our Clinical Trials Dashboard.
| Disease | Cell Type | Therapeutic or Technology | Institution | Stage | Project Objective | Details |
|---|---|---|---|---|---|---|
| Cancer, Solid Tumors | Adult or Tissue Stem Cell | Personalized cell therapy, Therapeutic Approach | BioEclipse Therapeutics INC. |  |
Clinical Trial, Phase 1 or Phase 1/2 | |
| B cell cancers, Blood Cancer, Cancer, Leukemia, Leukemia, Acute Myeloid (AML) | Adult or Tissue Stem Cell | Donor cell therapy, Therapeutic Approach | Stanford | |
Clinical Trial, Phase 1 or Phase 1/2 | |
| Brain Cancer, Cancer, Solid Tumors | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | Stanford | |
Clinical Trial, Phase 1 or Phase 1/2 | |
| Amyotrophic Lateral Sclerosis, Neurological Disorders | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach | Cedars-Sinai | |
Clinical Trial, Phase 1 or Phase 1/2 | |
| Neurological Disorders, Stroke | Embryonic Stem Cell | Donor cell therapy, Therapeutic Approach | Stanford | |
Clinical Trial, Phase 1 or Phase 1/2 | |
| Brain Cancer, Cancer, Solid Tumors | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | COH | |
Clinical Trial, Phase 1 or Phase 1/2 | |
| HIV/AIDS, Immune Disease, Infectious Disease | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UCSF | |
Clinical Trial, Phase 1 or Phase 1/2 | |
| Neurological Disorders, Parkinson's Disease | Vital Research Opportunity | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | Brain Neurotherapy Bio | |
Clinical Trial, Phase 1 or Phase 1/2 | |
| Corneal Damage, Vision Loss | Adult or Tissue Stem Cell | Personalized cell therapy, Therapeutic Approach | UCLA | |
Clinical Trial, Phase 1 or Phase 1/2 | |
| Brain Cancer, Breast Cancer, Cancer, Solid Tumors | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | COH | |
Clinical Trial, Phase 1 or Phase 1/2 | |
| Retinitis Pigmentosa, Vision Loss | Adult or Tissue Stem Cell | Donor cell therapy, Therapeutic Approach | Cedars-Sinai | |
Clinical Trial, Phase 1 or Phase 1/2 | |
| Cystinosis, Kidney Disease, Kidney Failure, Metabolic Disorders | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UCSD | |
Clinical Trial, Phase 1 or Phase 1/2 | |
| Diabetes, Metabolic Disorders, Type 1 diabetes | Adult or Tissue Stem Cell | Donor cell therapy, Therapeutic Approach | UCSF | |
Clinical Trial, Phase 1 or Phase 1/2 | |
| Blood Disorders, Severe Combined Immunodeficiency, X-linked (X-SCID) | Adult or Tissue Stem Cell | Antibody, Biologic, Therapeutic Approach | Jasper Therapeutics, Inc. | |
Clinical Trial, Phase 1 or Phase 1/2 | |
| Kidney Disease, Kidney Failure | Adult or Tissue Stem Cell | Donor cell therapy, Therapeutic Approach | Stanford | |
Clinical Trial, Phase 1 or Phase 1/2 | |
| Kidney Disease, Kidney Failure | Adult or Tissue Stem Cell | Donor cell therapy, Therapeutic Approach | Medeor Acquisition Corp. |  |
Clinical Trial, Phase 3 | |
| Cancer, Lung Cancer, Solid Tumors | Adult or Tissue Stem Cell | Antibody, Biologic, Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UCLA | |
Clinical Trial, Phase 1 or Phase 1/2 | |
| Blood Disorders, Bone Marrow Transplant and Viral Infection | Adult or Tissue Stem Cell | Donor cell therapy, Therapeutic Approach | CHLA | |
Clinical Trial, Phase 1 or Phase 1/2 | |
| Retinitis Pigmentosa, Vision Loss | Other | Donor cell therapy, Therapeutic Approach | jCyte |  |
Clinical Trial, Phase 2 | |
| Kidney Disease, Kidney Failure | Adult or Tissue Stem Cell | Donor cell therapy, Therapeutic Approach | Stanford | |
Clinical Trial, Phase 1 or Phase 1/2 | |
| Blood Disorders, Genetic Disorder, Immune Disease, Pediatrics, Severe Combined Immunodeficiency, Adenosine deaminase-deficient (ADA-SCID) | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UCLA | |
Clinical Trial, Phase 2 | |
| Blood Cancer, Cancer, HIV-related Lymphoma, HIV/AIDS, Infectious Disease | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UC Davis | |
Clinical Trial, Phase 1 or Phase 1/2 | |
| Blood Disorders, Immune Disease, Pediatrics, X-linked Chronic Granulomatous Disease | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UCLA | |
Clinical Trial, Phase 1 or Phase 1/2 | |
| Neurological Disorders | Gene Therapy (All), Gene Therapy, cell free, Nucleic acid based therapy, Therapeutic Approach | Cure Rare Disease |  |
IND | ||
| Heart Disease | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | Rejuvenate Bio | |
IND | ||
| Angelman Syndrome, Neurological Disorders, Pediatrics | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UC Davis | |
IND | |
| Neurological Disorders, Spinal Cord Injury | Embryonic Stem Cell | Donor cell therapy, Therapeutic Approach | UCSD | |
IND | |
| Neurological Disorders | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | Amplo Biotechnology Inc | |
IND | ||
| Cancer, Sarcoma, Solid Tumors | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | CHLA | |
IND | |
| Heart Disease, Heart failure | Antibody, Biologic, Therapeutic Approach | UCLA | |
IND | ||
| Blood Cancer, Cancer, Multiple Myeloma | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UCSF | |
IND | |
| Developmental Disorders, Genetic Disorder, Neurological Disorders, Pediatrics | Gene Therapy (All), Gene Therapy, cell free, Nucleic acid based therapy, Therapeutic Approach | Elpida Therapeutics | |
IND | ||
| Heart Disease, Heart failure | Adult or Tissue Stem Cell, Somatic Cell | Biologic, Exosomes based therapy, Therapeutic Approach | Cedars-Sinai | |
IND | |
| Cancer, Ovarian Cancer, Solid Tumors | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach | COH | |
IND | |
| Epilepsy, Intellectual Disability, Neurological Disorders | Gene Therapy (All), Gene Therapy, cell free, Nucleic acid based therapy, Therapeutic Approach | Mahzi Therapeutics | |
IND | ||
| Blood Disorders, Sickle Cell Disease | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UC Davis | |
IND | |
| Age-related macular degeneration, Vision Loss | Embryonic Stem Cell | Biologic, Therapeutic Approach | USC | |
IND | |
| Bone or Cartilage Disease, Cartilage defect | Somatic Cell | Donor cell therapy, Therapeutic Approach | UC Irvine | |
IND | |
| Cystic Fibrosis, Respiratory Disorders | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | Stanford | |
IND | |
| Blood Cancer, Cancer, Leukemia, Acute Myeloid (AML) | Small molecule therapy, Therapeutic Approach | Aspera Biomedicines, Inc. | |
IND | ||
| Age-related macular degeneration, Vision Loss | iPS Cell | Personalized cell therapy, Therapeutic Approach | UCLA | |
IND | |
| Genetic Disorder, Metabolic Disorders | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | Rampart Bioscience | |
IND | |
| Breast Cancer, Cancer, Melanoma, Solid Tumors | Somatic Cell | Donor cell therapy, Therapeutic Approach | Calidi Biotherapeutics, Inc. | |
IND | |
| Immune Disease | Adult or Tissue Stem Cell | Donor cell therapy, Therapeutic Approach | Ossium Health, Inc. | |
IND | |
| Neurological Disorders | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Personalized cell therapy, Therapeutic Approach | UC Davis | |
IND | |
| Blood Cancer, Cancer, Leukemia, Acute Myeloid (AML) | Cancer Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UCSF | |
IND | |
| Genetic Disorder, Metabolic Disorders, Neurological Disorders, Pediatrics | Somatic Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | Stanford | |
IND | |
| Blood Disorders, X-linked Chronic Granulomatous Disease | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | ImmunoVec | |
Clinical Trial, Phase 1 or Phase 1/2 | |
| Bone or Cartilage Disease, Cartilage defect | Embryonic Stem Cell | Donor cell therapy, Therapeutic Approach | USC | |
IND | |
| Skin Disease, Wounds, ulcers | Small molecule therapy, Therapeutic Approach | UCLA | |
IND |
