Active Awards Portfolio Dashboard
It takes a lot of effort to develop a promising stem cell research idea into an effective treatment that can help patients. CIRM funds a pipeline of projects spanning discovery, translation and clinical stage research. Check out our portfolio of active research awards in our interactive dashboard below. For a detailed list of CIRM-funded clinical trials, visit our Clinical Trials Dashboard.
| Disease | Cell Type | Therapeutic or Technology | Institution | Stage | Project Objective | Details |
|---|---|---|---|---|---|---|
| Angelman Syndrome, Neurological Disorders, Pediatrics | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UCLA |  |
Pre-IND/IDE or Equivalent | |
| Huntington's Disease, Neurological Disorders | Small molecule therapy, Therapeutic Approach | ReviR Therapeutics | |
Pre-IND/IDE or Equivalent | ||
| Brain Cancer, Cancer, Solid Tumors | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | USC | |
Pre-IND/IDE or Equivalent | ||
| Neurological Disorders, Parkinson's Disease | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | NysnoBio GT Neurology | |
Pre-IND/IDE or Equivalent | ||
| Blood Cancer, Blood Disorders, Cancer, Immune Disease | Antibody, Biologic, Therapeutic Approach | Maro Bio | |
Pre-IND/IDE or Equivalent | ||
| Epilepsy, Neurological Disorders | Embryonic Stem Cell | Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach | Neurona Therapeutics | |
Pre-IND/IDE or Equivalent | |
| Alpha Thalassemia Major, Anemia, Blood Disorders | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UCLA | |
Pre-IND/IDE or Equivalent | |
| Blood Disorders, Bone or Cartilage Disease, Metabolic Disorders | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | Stanford | |
Pre-IND/IDE or Equivalent | |
| Cancer, Ovarian Cancer, Solid Tumors | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach | UCLA | |
Pre-IND/IDE or Equivalent | |
| Neurological Disorders, Parkinson's Disease | Embryonic Stem Cell | Cell processing & handling, Donor cell therapy, Technology, Therapeutic Approach | Axent Biosciences Inc. | |
Pre-IND/IDE or Equivalent | |
| Amyotrophic Lateral Sclerosis, Neurological Disorders | Gene Therapy (All), Gene Therapy, cell free, Nucleic acid based therapy, Therapeutic Approach | AcuraStem Incorporated | |
Pre-IND/IDE or Equivalent | ||
| Metabolic Disorders | Gene Therapy (All), Gene Therapy, cell free, Nucleic acid based therapy, Therapeutic Approach | UCLA | |
Pre-IND/IDE or Equivalent | ||
| Other | Adult or Tissue Stem Cell | Small molecule therapy, Therapeutic Approach | UCSF | |
Pre-IND/IDE or Equivalent | |
| Age-related macular degeneration, Vision Loss | Somatic Cell | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | Ray Therapeutics, INC | |
Pre-IND/IDE or Equivalent | |
| Bone or Cartilage Disease, Immune Disease, Skin Disease, Tendon/Ligament/Connective Tissue Injury or Disorder | Biologic, Gene Therapy (All), Gene Therapy, cell free, Nucleic acid based therapy, Therapeutic Approach | Cedars-Sinai | |
Pre-IND/IDE or Equivalent | ||
| Blood Disorders | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UCLA | |
Pre-IND/IDE or Equivalent | |
| Heart Disease | Adult or Tissue Stem Cell | Biologic, Therapeutic Approach | UCSD | |
Pre-IND/IDE or Equivalent | |
| Metabolic Disorders | Gene Therapy (All), Gene Therapy, cell free, Nucleic acid based therapy, Therapeutic Approach | UCLA | |
Pre-IND/IDE or Equivalent | ||
| Danon Disease, Genetic Disorder, Metabolic Disorders | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UCSD | |
Pre-IND/IDE or Equivalent | |
| Blood Disorders, Genetic Disorder | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UCLA | |
Pre-IND/IDE or Equivalent | |
| Blood Cancer, Cancer, Multiple Myeloma | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach | COH | |
Pre-IND/IDE or Equivalent | |
| Corneal Damage, Vision Loss | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | UCLA | |
Pre-IND/IDE or Equivalent | ||
| Neurological Disorders, Parkinson's Disease | iPS Cell | Personalized cell therapy, Therapeutic Approach | BrainXell Therapeutics | |
Pre-IND/IDE or Equivalent | |
| Blood Disorders | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | ImmunoVec | |
Pre-IND/IDE or Equivalent | |
| HIV/AIDS, Infectious Disease | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UCLA | |
Pre-IND/IDE or Equivalent | |
| Corneal Damage, Vision Loss | Adult or Tissue Stem Cell | Biologic, Exosomes based therapy, Therapeutic Approach | UCLA | |
Pre-IND/IDE or Equivalent | |
| Lung Disease, Fibrosis, Respiratory Disorders | Gene Therapy (All), Gene Therapy, cell free, Nucleic acid based therapy, Therapeutic Approach | Rejuvenation Technologies, Inc. | |
Pre-IND/IDE or Equivalent | ||
| Cancer, Lung Cancer, Solid Tumors | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | USC | |
Pre-IND/IDE or Equivalent | |
| Diabetes, Metabolic Disorders | Personalized cell therapy, Therapeutic Approach | Stanford | |
Pre-IND/IDE or Equivalent | ||
| Breast Cancer, Cancer, Solid Tumors | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach | UC Irvine | |
Pre-IND/IDE or Equivalent | |
| B cell cancers, Blood Cancer, Cancer | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UC Davis | |
Pre-IND/IDE or Equivalent | ||
| Genetic Disorder, Neurological Disorders, Other, Pediatrics | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UCSD | |
Pre-IND/IDE or Equivalent | |
| Cancer, Prostate Cancer, Solid Tumors | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | USC | |
Pre-IND/IDE or Equivalent | ||
| Heart Disease, Hypertension, pulmonary arterial, Pulmonary Hypertension | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UCLA | |
Pre-IND/IDE or Equivalent | |
| Neurological Disorders, Spinal Cord Injury | Adult or Tissue Stem Cell | Donor cell therapy, Therapeutic Approach | UC Irvine | |
Pre-IND/IDE or Equivalent | |
| Duchenne Muscular Dystrophy, Skeletal/Smooth Muscle disorders | Somatic Cell | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | MyoGene Bio LLC | |
Pre-IND/IDE or Equivalent | |
| Genetic Disorder, Metabolic Disorders | Somatic Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | Immusoft Corporation | |
Pre-IND/IDE or Equivalent | |
| Blood Disorders, IPEX Syndrome | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | ImmunoVec | |
Pre-IND/IDE or Equivalent | |
| Neurological Disorders, Stroke | iPS Cell | Donor cell therapy, Therapeutic Approach | PAVIR | |
Pre-IND/IDE or Equivalent | |
| Cancer, Melanoma, Solid Tumors | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UCLA | |
Pre-IND/IDE or Equivalent | |
| Blood Cancer, Cancer, Multiple Myeloma | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach | UCLA | |
Pre-IND/IDE or Equivalent | |
| Brain Injury, hypoxic, ischemic, Neurological Disorders, Pediatrics | Adult or Tissue Stem Cell | Donor cell therapy, Therapeutic Approach | Sanford-Burnham | |
Pre-IND/IDE or Equivalent | |
| Neurological Disorders, Traumatic Brain Injury | Embryonic Stem Cell | Donor cell therapy, Therapeutic Approach | UC Irvine | |
Pre-IND/IDE or Equivalent | |
| Blood Disorders, Hyper IgM Syndrome, Immune Disease | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UCLA | |
Pre-IND/IDE or Equivalent | |
| Age-related macular degeneration, Vision Loss | Adult or Tissue Stem Cell | Donor cell therapy, Therapeutic Approach | Stanford | |
Pre-IND/IDE or Equivalent | |
| Bladder or Urinary Tract Disorder, Incontinence, Skeletal/Smooth Muscle disorders | iPS Cell | Personalized cell therapy, Therapeutic Approach | Stanford | |
Pre-IND/IDE or Equivalent | |
| Intestinal Disease, Metabolic Disorders, Neurological Disorders, Pediatrics | iPS Cell | Donor cell therapy, Therapeutic Approach | CHLA | |
Pre-IND/IDE or Equivalent | |
| Blood Disorders, Severe Combined Immunodeficiency, Artemis deficient (ART-SCID) | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UCSF |  |
Clinical Trial, Phase 3 | |
| Epilepsy, Neurological Disorders | Embryonic Stem Cell | Donor cell therapy, Therapeutic Approach | Neurona Therapeutics |  |
Clinical Trial, Phase 1 or Phase 1/2 | |
| Retinitis Pigmentosa, Vision Loss | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | Ray Therapeutics, INC | |
Clinical Trial, Phase 1 or Phase 1/2 |
