Active Awards Portfolio Dashboard

It takes a lot of effort to develop a promising stem cell research idea into an effective treatment that can help patients. CIRM funds a pipeline of projects spanning discovery, translation and clinical stage research. Check out our portfolio of active research awards in our interactive dashboard below. For a detailed list of CIRM-funded clinical trials, visit our Clinical Trials Dashboard.

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Disease Cell Type Therapeutic or Technology Institution Stage Project Objective Details
Traumatic Brain Injury Embryonic Stem Cell Exosomes based therapy UC Irvine
Development Candidate, Proof of Concept, Research Insights
HIV/AIDS,
Immune Disease
Adult Stem Cell Gene-modified, personalized cell therapy UCSF
Clinical Trial, Phase 1 or Phase 1/2
Spina Bifida Adult Stem Cell Donor cell therapy UC Davis
Clinical Trial, Phase 1 or Phase 1/2
Sickle Cell Disease Adult Stem Cell Gene-modified, personalized cell therapy Boston Children's Hospital
Clinical Trial, Phase 2
Beta Thalassemia,
Sickle Cell Disease
Adult Stem Cell Diagnostic Test UCSF
Regulated Lab Test, Ready for Validation
Leukemia, Acute Myeloid (AML) Cancer Stem Cell Antibody Immune-Onc Therapeutics
Clinical Trial, Phase 1 or Phase 1/2
Brain Cancer Adult Stem Cell Gene-modified, personalized cell therapy COH
Clinical Trial, Phase 1 or Phase 1/2
Multiple Myeloma Adult Stem Cell Gene-modified, donor cell therapy UCLA
Pre-IND/IDE or Equivalent
Melanoma Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Pre-IND/IDE or Equivalent
Amyotrophic Lateral Sclerosis Adult Stem Cell Gene-modified, donor cell therapy Cedars-Sinai
Clinical Trial, Phase 1 or Phase 1/2
Stroke Embryonic Stem Cell Donor cell therapy Stanford
Clinical Trial, Phase 1 or Phase 1/2
Brain Cancer Adult Stem Cell Gene-modified, personalized cell therapy Stanford
Clinical Trial, Phase 1 or Phase 1/2
Heart failure Embryonic Stem Cell Donor cell therapy Stanford
Clinical Trial, Phase 1 or Phase 1/2
Heart Disease iPS Cell Donor cell therapy UC Davis
Development Candidate, Proof of Concept
Pancreatic Cancer Cancer Stem Cell Small molecule therapy UCSD
Development Candidate, Proof of Concept
Liver Disease iPS Cell Diagnostic Test UCSF
Development Candidate, Proof of Concept
Brain Cancer,
Neurological Disorders
Embryonic Stem Cell Exosomes based therapy UC Irvine
Development Candidate, Proof of Concept
Anemia Adult Stem Cell,
iPS Cell
Small molecule therapy Stanford
Development Candidate, Proof of Concept
Heart failure iPS Cell Exosomes based therapy Stanford
Development Candidate, Proof of Concept
Angelman Syndrome,
Autism
iPS Cell Gene Therapy, cell free UC Davis
Development Candidate, Proof of Concept
Epidermolysis Bullosa iPS Cell Gene-modified, personalized cell therapy Stanford
Development Candidate, Proof of Concept
Ovarian Cancer iPS Cell Gene-modified, donor cell therapy UCSD
Development Candidate, Proof of Concept
Amyotrophic Lateral Sclerosis Adult Stem Cell Donor cell therapy UCSD
Development Candidate, Proof of Concept
Heart Disease iPS Cell Model system development Stanford
Development Candidate, Proof of Concept
Sickle Cell Disease Adult Stem Cell Gene-modified, personalized cell therapy UCSF
Clinical Trial, Phase 1 or Phase 1/2
B cell cancers,
Leukemia,
Leukemia, Acute Myeloid (AML)
Adult Stem Cell Donor cell therapy Stanford
Clinical Trial, Phase 1 or Phase 1/2
Cartilage defect Embryonic Stem Cell Donor cell therapy USC
IND
Blood Cancer Adult Stem Cell Gene-modified, personalized cell therapy UCSD
IND
Muscular Dystrophy Protein/peptide therapy Juvena Therapeutics Inc.
Pre-IND/IDE or Equivalent
Stroke iPS Cell Donor cell therapy UCLA
Pre-IND/IDE or Equivalent
Heart Disease Adult Stem Cell Antibody UCLA
Pre-IND/IDE or Equivalent
IPEX Syndrome Adult Stem Cell Gene-modified, personalized cell therapy ImmunoVec
Pre-IND/IDE or Equivalent
Brain Cancer Somatic Cell Gene-modified, personalized cell therapy UCSF
Pre-IND/IDE or Equivalent
Heart Disease iPS Cell Protein/peptide therapy Regencor, Inc.
Pre-IND/IDE or Equivalent
Metabolic Disorders Somatic Cell Gene-modified, personalized cell therapy Immusoft Corporation
Pre-IND/IDE or Equivalent
Duchenne Muscular Dystrophy Somatic Cell Gene Therapy, cell free MyoGene Bio LLC
Pre-IND/IDE or Equivalent
B cell cancers Somatic Cell Gene-modified, personalized cell therapy UCSF
Pre-IND/IDE or Equivalent
Spinal Cord Injury Adult Stem Cell Donor cell therapy UC Irvine
Pre-IND/IDE or Equivalent
Heart Disease iPS Cell Model system development Organos, Inc.
Tool/Resources/Bottleneck
Heart failure Adult Stem Cell Nucleic acid based therapy Cedars-Sinai
Development Candidate, Proof of Concept
Neurological Disorders iPS Cell Gene Therapy, cell free Navega Therapeutics
Development Candidate, Proof of Concept
Spinal Cord Injury iPS Cell Other Components Stanford
Development Candidate, Proof of Concept
Multiple Myeloma Somatic Cell Gene-modified, personalized cell therapy UCSF
Development Candidate, Proof of Concept
Multiple Sclerosis Adult Stem Cell Small molecule therapy Scripps
Development Candidate, Proof of Concept
Kidney Disease Somatic Cell Gene Therapy, cell free UCSF
Development Candidate, Proof of Concept
Neurological Disorders,
Sanfilippo Syndrome/MPS III
iPS Cell Gene-modified, personalized cell therapy UC Irvine
Development Candidate, Proof of Concept
Huntington's Disease iPS Cell Gene Therapy, cell free UCSD
Development Candidate, Proof of Concept
Cartilage defect Adult Stem Cell Biologic The Stone Research Foundation for Sports Medicine and Arthritis
Development Candidate, Proof of Concept
Cartilage defect,
Osteoarthritis
Embryonic Stem Cell Donor cell therapy Scripps Health
Development Candidate, Proof of Concept
Type 1 diabetes Embryonic Stem Cell,
iPS Cell
Biologic UCLA
Development Candidate, Proof of Concept

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