Active Awards Portfolio Dashboard

It takes a lot of effort to develop a promising stem cell research idea into an effective treatment that can help patients. CIRM funds a pipeline of projects spanning discovery, translation and clinical stage research. Check out our portfolio of active research awards in our interactive dashboard below. For a detailed list of CIRM-funded clinical trials, visit our Clinical Trials Dashboard.

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Disease Cell Type Therapeutic or Technology Institution Stage Project Objective Details
Immune Disease,
Severe Combined Immunodeficiency, X-linked (X-SCID)
Adult Stem Cell Gene-modified, personalized cell therapy St. Jude
Clinical Trial, Phase 1 or Phase 1/2
Skeletal/Smooth Muscle disorders Adult Stem Cell Protein/peptide therapy Stanford
Research Insights
B cell cancers,
Leukemia
Cancer Stem Cell Antibody COH
Development Candidate, Proof of Concept
Liver Disease Directly Reprogrammed Cell Gene modification UCSF
Development Candidate
Heart Disease iPS Cell Model system development UC Berkeley
Proof of Concept
Colon Cancer Cancer Stem Cell Small molecule therapy COH
Development Candidate, Proof of Concept
Heart Disease iPS Cell Donor cell therapy Stanford
Development Candidate, Proof of Concept
Heart Disease iPS Cell Personalized cell therapy UC Davis
Proof of Concept
Blood Disorders Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Development Candidate, Proof of Concept
Other Embryonic Stem Cell,
iPS Cell
Cell processing & handling X-Therma
Proof of Concept, Tool/Resources/Bottleneck
Cancer Embryonic Stem Cell Specific Cell Type Derivation UCLA
Tool/Resources/Bottleneck
Huntington's Disease Embryonic Stem Cell Small molecule therapy Rumi Scientific CA
Development Candidate
Neurological Disorders,
Zika virus
Adult Stem Cell,
iPS Cell
Vaccine UCLA
Development Candidate
Traumatic Brain Injury Embryonic Stem Cell Donor cell therapy UC Irvine
Development Candidate
Stroke Embryonic Stem Cell Donor cell therapy Stanford
IND
Leukemia, Acute Myeloid (AML) Cancer Stem Cell Antibody Cellerant Therapeutics
IND
Stroke Adult Stem Cell Gene-modified, donor cell therapy SanBio, Inc.
Clinical Trial, Phase 2
Alpha Thalassemia Major Adult Stem Cell Donor cell therapy UCSF
Clinical Trial, Phase 1 or Phase 1/2
Cancer Cancer Stem Cell Gene-modified, personalized cell therapy UCSD
Pre-IND/IDE or Equivalent
Amyotrophic Lateral Sclerosis Adult Stem Cell Personalized cell therapy BrainStorm
Clinical Trial, Phase 3
Blood Cancer Adult Stem Cell Gene-modified, donor cell therapy Angiocrine
Clinical Trial, Phase 1 or Phase 1/2
B cell cancers,
Leukemia
Cancer Stem Cell Antibody UCSD
Clinical Trial, Phase 1 or Phase 1/2
Sickle Cell Disease Adult Stem Cell Gene-modified, personalized cell therapy Stanford
IND
Type 1 diabetes Embryonic Stem Cell Donor cell therapy ViaCyte
Clinical Trial, Phase 1 or Phase 1/2
Kidney Failure Adult Stem Cell Biologic Humacyte
Clinical Trial, Phase 3
Leukemia, Acute Myeloid (AML) Cancer Stem Cell Antibody Forty Seven
Clinical Trial, Phase 1 or Phase 1/2
Brain Cancer Adult Stem Cell Gene-modified, personalized cell therapy COH
Clinical Trial, Phase 1 or Phase 1/2
Arthritis,
Osteoarthritis
Adult Stem Cell Small molecule therapy Calibr
Clinical Trial, Phase 1 or Phase 1/2
Blood Cancer,
Bone Marrow Transplant and Viral Infection
Adult Stem Cell Donor cell therapy CHLA
Clinical Trial, Phase 1 or Phase 1/2
Multiple Myeloma Adult Stem Cell Gene-modified, personalized cell therapy Poseida Therapeutics
Clinical Trial, Phase 1 or Phase 1/2
Epidermolysis Bullosa iPS Cell Gene-modified, personalized cell therapy Stanford
Pre-IND/IDE or Equivalent
Leukemia, Acute Myeloid (AML) Cancer Stem Cell Small molecule therapy UCSD
Pre-IND/IDE or Equivalent
Leukemia, Acute Myeloid (AML) Embryonic Stem Cell Donor cell therapy UCSD
Pre-IND/IDE or Equivalent
Respiratory Disorders Directly Reprogrammed Cell Model system development UCSF
Research Insights
Ovarian Cancer Cancer Stem Cell Nucleic acid based therapy Loma Linda University
Proof of Concept
Vascular Disease iPS Cell Donor cell therapy PAVIR
Proof of Concept, Research Insights
Bone or Cartilage Disease iPS Cell Donor cell therapy Cedars-Sinai
Proof of Concept, Research Insights
Parkinson's Disease iPS Cell Small molecule therapy Zenobia Therapeutics
Proof of Concept, Research Insights
Bone or Cartilage Disease Adult Stem Cell Donor cell therapy UCLA
Proof of Concept
Age-related macular degeneration iPS Cell Exploring disease mechanisms UCSD
Research Insights
Hemophilia A Adult Stem Cell Gene modification COH
Development Candidate, Proof of Concept
Epilepsy Embryonic Stem Cell Donor cell therapy Neurona Therapeutics
Development Candidate
Type 1 diabetes Embryonic Stem Cell Gene-modified, donor cell therapy UCSD
Development Candidate, Proof of Concept
Type 1 diabetes Embryonic Stem Cell Gene-modified, donor cell therapy ViaCyte
Development Candidate
Skeletal/Smooth Muscle disorders Adult Stem Cell Small molecule therapy Stanford
Development Candidate
Spinal Cord Injury Embryonic Stem Cell Donor cell therapy UCSD
Development Candidate
Liver Disease Embryonic Stem Cell Donor cell therapy Stanford
Development Candidate, Proof of Concept
Muscular Dystrophy Embryonic Stem Cell,
iPS Cell
Personalized cell therapy UCLA
Development Candidate
Stroke iPS Cell Donor cell therapy UCLA
Development Candidate
Leukemia, Acute Myeloid (AML) Cancer Stem Cell Antibody UCSD
Development Candidate, Proof of Concept

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