All CIRM Grants

Institution Researcher name Grant Type Grant Title Award Value
Gladstone Institutes Warner Greene Early Translational I Maximizing the Safety of Induced Pluripotent Stem Cells as an Infusion Therapy: Limiting the Mutagenic Threat of Retroelement Retrotransposition during iPSC Generation, Expansion and Differentiation $1,324,011
University of Southern California Wange Lu Basic Biology I Defining the molecular mechanisms of somatic cell reprogramming $1,365,580
Gladstone Institutes Sheng Ding Shared Labs Center for hESC Research $1,440,164
Stanford University Gerald Crabtree Basic Biology IV Mechanism and Utility of Direct Neuronal Conversion with a MicroRNA-Chromatin Switch $1,392,426
University of California, San Diego Alysson Muotri Early Translational IV A drug-screening platform for autism spectrum disorders using human astrocytes $1,656,456
City College Of San Francisco Carin Zimmerman Bridges Stem Cell Training Enhancement Program $2,732,437
University of California, Berkeley Steven Conolly Tools and Technologies II Magnetic Particle Imaging: A Novel Ultra-sensitive Imaging Scanner for Tracking Stem Cells In Vivo $1,311,596
University of California, San Francisco Holger Willenbring SEED Grant Induction of pluripotency in fibroblasts by fusion with enucleated human embryonic stem cell syncytia $329,245
University of California, Santa Cruz Lindsay Hinck Shared Labs Shared Stem Cell Facility $1,721,129
University of California, Irvine Aileen Anderson Basic Biology II Role of the microenvironment in human iPS and NSC fate and tumorigenesis $1,256,194
Scripps Research Institute Sheng Ding New Faculty I Reprogramming of human somatic cells back to pluripotent embryonic stem cells $1,393,876
University of California, Los Angeles Owen Witte Basic Biology IV Trop2 dependent and independent mechanisms of self-renewal in human cancer stem cells $1,254,960
University of California, Los Angeles Lili Yang Basic Biology V Differentiation of Human Hematopoietic Stem Cells into iNKT Cells $614,400
Samumed, LLC John Hood Disease Team Therapy Planning I Clinical Development of an osteoinductive therapy to prevent osteoporosis-related fractures $99,110
University of California, San Diego Karl Willert Tools and Technologies II Homologous recombination in human pluripotent stem cells using adeno-associated virus. $1,659,043
Stanford University Aaron Hsueh SEED Grant Patient-specific cells with nuclear transfer $629,653
University of California, Los Angeles Hsian-Rong Tseng Tools and Technologies I Microfluidic Platform for Screening Chemically Defined Conditions that Facilitate Clonal Expansion of Human Pluripotent Stem Cells $914,096
University of California, Irvine Leslie Thompson Early Translational II A hESc-based Development Candidate for Huntington's Disease $4,045,253
University of California, San Diego Binhai Zheng Basic Biology III Generation and characterization of corticospinal neurons from human embryonic stem cells $1,355,063
California Institute of Technology David Tirrell Basic Biology V Engineered matrices for control of lineage commitment in human pancreatic stem cells $526,896
University of California, Irvine Peter Bryant Training Grant I-1 Stem Cell Research Training Grant $1,935,487
University of Southern California Qilong Ying SEED Grant Self-renewal of human embryonic stem cells $621,421
University of California, Irvine Orhan NALCIOGLU Tools and Technologies I A Multimodality Molecular Imaging Systen (MRSPECT) for in Vivo Stem Cell Tracking $719,798
City of Hope Karen Aboody Disease Team Research I Stem Cell-mediated Therapy for High-grade Glioma: Toward Phase I-II Clinical Trials $18,015,429
University of Southern California Paula Cannon Tools and Technologies III Site-specific gene editing in hematopoietic stem cells as an anti-HIV therapy $1,499,400
University of California, San Francisco Andrew Leavitt Comprehensive Grant Understanding hESC-based Hematopoiesis for Therapeutic Benefit $2,460,822
University of California, Los Angeles Gene Block Major Facilities UCLA CIRM Institute $19,854,900
University of California, San Diego Eric Adler Early Translational III Identification of Novel Therapeutics for Danon Disease Using an iPS Model of the Disease $1,701,575
Children's Hospital of Los Angeles Tracy Grikscheit New Faculty Physician Scientist The generation and expansion of tissue-engineered small intestine from human stem/ progenitor cells: a preclinical study of functional translation $3,146,160
Scripps Research Institute Kristin Baldwin Basic Biology III Identifying sources of mutation in human induced pluripotent stem cells by whole genome sequencing $1,705,500
University of California, Irvine Vincent Procaccio SEED Grant Mitochondrial Dysfunction in Embryonic Stem Cells $245,582
University of California, Berkeley Ellen Robey Transplantation Immunology Human Immune System Mouse models as preclinical platforms for stem cell derived grafts $1,005,605
University of California, Los Angeles Amander Clark New Cell Lines Generation of Pluripotent Cell Lines from Human Embryos $1,168,501
Stanford University Renee Reijo Pera Comprehensive Grant Human oocyte development for genetic, pharmacological and reprogramming applications $2,298,411
Ludwig Institute for Cancer Research Webster Cavenee Disease Team Planning Stem Cell-Mediated Oncocidal Therapy of Primary & Metastatic Brain Tumors $3,867
University of California, Davis Nancy Lane Disease Team Therapy Development - Research Treatment of osteoporosis with endogenous Mesenchymal stem cells $19,999,867
Cellular Dynamics International Thomas Novak hiPSC Derivation Generation and characterization of high-quality, footprint-free human induced pluripotent stem cell lines from 3,000 donors to investigate multigenic diseases $16,000,000
Sanford-Burnham Medical Research Institute Mark Mercola Research Training II Type III CIRM Stem Cell Research Training Program $2,856,693
University of California, Merced Jennifer Manilay New Faculty I Enhancing Survival of Embryonic Stem Cell-Derived Grafts by Induction of Immunological Tolerance $1,576,404
University of California, Los Angeles Irvin Chen SEED Grant Genetic modification of the human genome to resist HIV-1 infection and/or disease progression $616,800
Jackson Laboratory West Pali Kaur Early Translational I Mouse Models for Stem Cell Therapeutic Development $3,759,134
University of California, Los Angeles Luisa Iruela-Arispe Basic Biology I Molecular Characterization and Functional Exploration of Hemogenic Endothelium $1,371,477
University of California, Davis Alice Tarantal Shared Labs Translational Human Embryonic Stem Cell Shared Research Facility $2,000,000
University of California, San Diego Ananda Goldrath Basic Biology IV Mechanisms to protect hESC-derived cells from allogenic immune rejection $1,161,000
Gladstone Institutes Steven Finkbeiner Early Translational IV Development of Novel Autophagy Inducers to Block the Progression of and Treat Amyotrophic Lateral Sclerosis (ALS) and Other Neurodegenerative Diseases $2,278,080
Humboldt State University Jacob Varkey Bridges CIRM Bridges to Stem Cell Research Certificate Program $3,335,098
Stanford University Theo Palmer Tools and Technologies II Development of small molecule screens for autism using patient-derived iPS cells $1,797,606
University of California, San Francisco Didier Stainier SEED Grant Endodermal differentiation of human ES cells $611,027
Children's Hospital of Los Angeles David Warburton Shared Labs hESC Facility $1,750,259
University of California, Irvine Marian Waterman Basic Biology II TCF-3: A Wnt Pathway Effector and Nanog Regulator in Pluripotent Stem Cell Self-Renewal $1,259,879
University of California, Riverside Douglas Ethell New Faculty I ES-Derived Cells for the Treatment of Alzheimer's Disease $621,639
University of California, San Diego David Traver Basic Biology IV DECIPHERING THE INSTRUCTIONS FOR VERTEBRATE HSC SPECIFICATION AND AMPLIFICATION. $1,363,698
University of California, Los Angeles Denis Evseenko Basic Biology V Promoting survival and countering hypertrophy of pluripotent stem cell (PSC)-derived chondrocytes $1,146,468
Sanford-Burnham Medical Research Institute Stuart Lipton Disease Team Therapy Planning I hESC-derived NPCs Programmed with MEF2C for Cell Transplantation in Parkinson’s Disease $96,448
University of California, Santa Barbara Peter Coffey Research Leadership Development of Cellular Therapies for Retinal Disease $4,850,116
University of Southern California Peter Laird SEED Grant Screening for Oncogenic Epigenetic Alterations in Human ES Cells $647,431
Fluidigm Corporation Marc Unger Tools and Technologies I Scaleup of Versatile, Fully Automated, Microfluidic Cell Culture System $749,518
University of California, San Diego Alysson Muotri Early Translational II Developing a drug-screening system for Autism Spectrum Disorders using human neurons $1,376,198
City of Hope Larry Couture Tools and Technologies III Development of a scalable, practical, and transferable GMP-compliant suspension culture-based differentiation process for cardiomyocyte production from human embryonic stem cells. $899,728
University of California, Irvine Lisa Flanagan Basic Biology V Molecular basis of plasma membrane characteristics reflecting stem cell fate potential $994,108
Scripps Research Institute Peter Schultz Training Grant I-2 Training Grant I $1,021,395
Stanford University Michael Clarke Basic Biology III USP16 controls stem cell number: implications for Down Syndrome $1,263,826
Stanford University Susan McConnell SEED Grant Optimization of guidance response in human embryonic stem cell derived midbrain dopaminergic neurons in development and disease $607,363
University of California, Los Angeles Michael Phelps Tools and Technologies I Novel Tools and Technologies for Translational PET Imaging of Cell-based Therapies $914,039
Stanford University Gary Steinberg Disease Team Research I Embryonic-Derived Neural Stem Cells for Treatment of Motor Sequelae following Sub-cortical Stroke $18,026,648
University of Southern California Qilong Ying Tools and Technologies III Embryonic stem cell-based generation of small animal models for assessing human cellular therapies $1,334,160
University of California, Irvine Douglas Wallace Comprehensive Grant The Dangers of Mitochondrial DNA Heteroplasmy in Stem Cells Created by Therapeutic Cloning $1,790,133
University of California, Merced John White Major Facilities Stem Cell Instrumentation Foundry $4,341,321
University of Southern California Toshio Miki Early Translational III Generation of hepatic cell from placental stem cell for congenital metabolic disorders $1,750,375
Stanford University Alan Cheng New Faculty Physician Scientist Enhancing hair cell regeneration in mouse and human inner ear $3,091,595
University of California, San Francisco John Murnane Basic Biology III Genomic instability during culturing of human embryonic stem cells $1,070,919
University of California, Davis A. Reddi SEED Grant hESCs for Articular Cartilage Regeneration $301,703
Stanford University Judith Shizuru Transplantation Immunology Purified allogeneic hematopoietic stem cells as a platform for tolerance induction $1,233,275
Gladstone Institutes Bruce Conklin New Cell Lines Induced Pluripotent Stem Cells for Cardiovascular Diagnostics $1,708,560
Gladstone Institutes Deepak Srivastava Comprehensive Grant microRNA Regulation of Cardiomyocyte Differentiation from Human Embryonic Stem Cells $2,994,719
Children's Hospital of Oakland Research Institute Mark Walters Disease Team Planning CIRM Disease Team Planning Award $16,939
University of California, Davis Vicki Wheelock Disease Team Therapy Development - Research MSC engineered to produce BDNF for the treatment of Huntington's disease $17,857,797
Coriell Institute for Medical Research Dorit Berlin hPSC Repository The CIRM Human Pluripotent Stem Cell Biorepository – A Resource for Safe Storage and Distribution of High Quality iPSCs $9,942,175
University of California, Davis Frederick Meyers Research Training II Stem Cell Training Program $5,822,412
University of California, Los Angeles Hanna Mikkola New Faculty I Mechanisms of Hematopoietic stem cell Specification and Self-Renewal $2,286,900
University of California, San Francisco Robert Blelloch SEED Grant MicroRNA Regulation of Human Embryonic Stem Cell Self-Renewal and Differentiation $605,886
Parkinson's Institute J. William Langston Early Translational I Using patient-specific iPSC derived dopaminergic neurons to overcome a major bottleneck in Parkinson's disease research and drug discovery $3,698,646
University of California, Los Angeles Bennett Novitch Basic Biology I Molecular Characterization of hESC and hIPSC-Derived Spinal Motor Neurons $1,229,922
University of California, Los Angeles Scott Waugh Shared Labs CIRM Shared Research Laboratories $2,000,000
Stanford University Roel Nusse Basic Biology IV Asymmetric stem cell division oriented by a local self-renewing signal $1,039,058
University of California, Los Angeles Stanley Nelson Early Translational from Disease Team Conversion Combination therapy to Enhance Antisense Mediated Exon Skipping for Duchenne Muscular Dystrophy $1,823,545
Pasadena City College Pamela Eversole-Cire Bridges Bridges to Stem Cell Research $3,823,076
University of California, Los Angeles Richard Gatti Tools and Technologies II Use of hiPSCs to develop lead compounds for the treatment of genetic diseases $1,833,054
University of California, Davis Ebenezer Yamoah SEED Grant Hair Cells and Spiral Ganglion Neuron Differentiation from Human Embryonic Stem Cells $458,071
University of California, Riverside Prudence Talbot Shared Labs A Stem Cell Core Facility for Studying Human Embryonic Stem Cell Differentiation $1,679,818
University of California, San Diego Dong-Er Zhang Basic Biology II RUNX1 in maintenance, expansion, and differentiation of therapeutic pluripotent stem cells $1,371,540
Salk Institute for Biological Studies Dana Jones New Faculty I Characterization of mechanisms regulating de-differentiation and the re-acquisition of stem cell identity $2,134,100
Stanford University Michelle Monje Basic Biology IV Stem Cell Mechanisms Governing Discrete Waves of Gliogenesis in the Childhood Brain $1,264,248
Cedars-Sinai Medical Center Paul Noble Basic Biology V Innate Immune Regulation of Lung Alveolar Stem Cell Renewal in Mouse and Man $624,816
Cedars-Sinai Medical Center Clive Svendsen Disease Team Therapy Planning I Stem Cells Secreting GDNF for the Treatment of ALS $63,487
University of California, San Diego Eugene Yeo Basic Biology III Neural and general splicing factors control self-renewal, neural survival and differentiation $1,287,619
University of California, Irvine Thomas Lane SEED Grant Human Embryonic Stem Cells and Remyelination in a Viral Model of Demyelination $368,081
Gamma Medica-Ideas, Inc. Douglas Wagenaar Tools and Technologies I A Novel SPECT Microscopy System for 3D Imaging of Single Stem Cells In Vivo $800,065
City of Hope David DiGiusto Early Translational II Development of RNA-based approaches to stem cell gene therapy for HIV $3,097,160
University of Southern California Toshio Miki Tools and Technologies III Development of a clinical-grade extracorporeal liver support system using human induced pluripotent stem cell-derived hepatic cells $1,257,372

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