All CIRM Grants

Institution Researcher name Grant Type Grant Title Award Value
University of California, Los Angeles Dennis Slamon Disease Team Therapy Development III A Phase I dose escalation and expansion clinical trial of the novel first-in-class Polo-like Kinase 4 (PLK4) inhibitor, CFI-400945 in patients with advanced solid tumors $5,683,693
University of California, San Diego Thomas Kipps Disease Team Therapy Development III Therapeutic Eradication of Cancer Stem Cells with UC-961 (Cirmtuzumab) $4,179,598
Stanford University Irving Weissman Disease Team Therapy Development III Clinical Investigation of a Humanized Anti-CD47 Antibody in Targeting Cancer Stem Cells in Hematologic Malignancies and Solid Tumors $6,505,568
University of California, Los Angeles Donald Kohn Disease Team Therapy Development III Clinical Trial of Stem Cell Gene Therapy for Sickle Cell Disease $13,145,465
University of California, Davis Peter Belafsky Disease Team Therapy Development III Tissue Engineered Recellularized Laryngotracheal Implants $3,181,162
University of Southern California Mark Humayun Disease Team Therapy Development III Phase 1 Safety Assessment of CPCB-RPE1, hESC-derived RPE Cell Coated Parylene Membrane Implants, in Patients with Advanced Dry Age Related Macular Degeneration $16,339,827
Gladstone Institutes, J. David Deepak Srivastava Conference Keystone Symposia, "Stem Cells and Reprogramming" $50,000
University of California, Davis Mark Yarborough Conference Stem Cell Research for Neurological Disorders: A Case Study in Ethical and Policy Issues in ALS Research $1,020
University of California, San Francisco Jeffrey Rosenfeld Conference California ALS Research Summit 2014 $8,563
Alliance Forum Foundation George Hara Conference 2013 World Alliance Forum in San Francisco $3,500
University of California, Los Angeles Dana Jones Conference 7th CA/HSCI Junior PI Conference: Stem Cells 2.0 $2,500
Sanford Consortium for Regenerative Medicine Edward Holmes Conference The Sanford Consortium for Regenerative Medicine's Scientific Symposium and the Regen Med Partnering Forum at Stem Cell Meeting on the Mesa VIII $35,000
University of California, San Francisco Regis Kelly Conference The Science of Staying Younger Longer $6,500
University of California, Davis Alice Tarantal Conference 12th Annual Gene Therapy Symposium for Heart, Lung, and Blood Diseases $8,000
Scripps Research Institute Jeanne Loring Conference World Stem Cell Summit $30,000
University of California, Los Angeles Donald Kohn Early Translational IV Beta-Globin Gene Correction of Sickle Cell Disease in Hematopoietic Stem Cells $1,651,884
Salk Institute for Biological Studies Inder Verma Early Translational IV Development of a cell and gene based therapy for hemophilia $2,298,634
Human BioMolecular Research Institute John Cashman Early Translational IV Improving Existing Drugs for Long QT Syndrome type 3 (LQT3) by hiPSC Disease-in-Dish Model $6,361,369
University of California, Los Angeles Gerald Lipshutz Early Translational IV Gene therapy-corrected autologous hepatocyte-like cells from induced pluripotent stem cells for the treatment of pediatric single enzyme disorders $1,801,629
Cedars-Sinai Medical Center Dan Gazit Early Translational IV Gene Targeting to Endogenous Stem Cells for Segmental Bone Fracture Healing $5,121,514
University of California, San Diego Alysson Muotri Early Translational IV A drug-screening platform for autism spectrum disorders using human astrocytes $1,656,456
Gladstone Institutes, J. David Steven Finkbeiner Early Translational IV Development of Novel Autophagy Inducers to Block the Progression of and Treat Amyotrophic Lateral Sclerosis (ALS) and Other Neurodegenerative Diseases $2,049,053
Numerate, Inc. John Griffin Early Translational IV Use of human iPSC-derived neurons from Huntington’s Disease patients to develop novel, disease-modifying small molecule structural corrector drug candidates targeting the unique, neurotoxic conformation of mutant huntingtin $520,015
Sanford Burnham Prebys Medical Discovery Institute Stuart Lipton Early Translational IV Programming Human ESC-derived Neural Stem Cells with MEF2C for Transplantation in Stroke $1,020,815
The Scintillon Institute Stuart Lipton Early Translational IV Programming Human ESC-derived Neural Stem Cells with MEF2C for Transplantation in Stroke $1,103,185
Stanford University Michele Calos Early Translational IV Engineered iPSC for therapy of limb girdle muscular dystrophy type 2B $1,876,253
University of California, Los Angeles Robert Reiter Early Translational IV Clinical Development of an N-cadherin Antibody to Target Cancer Stem Cells $4,075,668
University of California, Los Angeles Zack Jerome Early Translational IV Stem Cell Programming With Chimeric Antigen Receptors to Eradicate HIV Infection $4,925,166
University of California, Irvine Magdalene Seiler Early Translational IV Restoring vision by sheet transplants of retinal progenitors and retinal pigment epithelium (RPE) derived from human embryonic stem cells (hESCs) $3,998,948
Stanford University Julien Sage Conference 3rd International RB conference $10,000
OCTANe Foundation for Innovation Matthew Jenusaitis Conference Orange County Summit on Regenerative Medicine (OCSRM) $2,500
University of California, San Francisco Peter Stock Conference IPITA 2013 - 14th World Congress of the International Pancreas and Islet transplant Association $10,000
University of California, San Diego Joan Heller Brown Conference International Society for Heart Research (ISHR) XX1 World Congress $10,000
Cedars-Sinai Medical Center Barry Stripp Research Leadership Epithelial progenitors and the stromal niche as therapeutic targets in lung disease $4,841,830
Stanford University Hiromitsu Nakauchi Research Leadership Generation of functional cells and organs from iPSCs $5,426,810
University of California, San Diego Eric Ahrens Research Leadership Molecular Imaging for Stem Cell Science and Clinical Application $5,920,899
Sangamo BioSciences, Inc. Fyodor Urnov Strategic Partnership II A Treatment For Beta-thalassemia via High-Efficiency Targeted Genome Editing of Hematopoietic Stem Cells $2,760,540
University of California, San Diego John Ravits Conference Cell Therapy for amyotrophic Lateral Sclerosis (ALS) -Testing the Limits: What should we use as preclinical standards of clinical trials? $7,193
University of California, Santa Cruz Camilla Forsberg Conference UCSC Frontiers of Stem Cells and Aging Symposium $24,405
University of California, San Diego Shu Chien Conference The 14th UC Systemwide Bioengineering Symposium $5,000
University of California, Los Angeles Brigitte Gomperts Tissue Collection for Disease Modeling Using human induced pluripotent stem cells to improve our understanding of Idiopathic Pulmonary Fibrosis $811,231
Stanford University Joseph Wu Tissue Collection for Disease Modeling Tissue Collection for Accelerating iPSC Research in Cardiovascular Diseases $1,291,832
University of California, San Diego Kang Zhang Tissue Collection for Disease Modeling Generation of fibroblast cell lines in patients with common blinding eye diseases $1,034,425
University of California, San Diego Joseph Gleeson Tissue Collection for Disease Modeling CIRM Tissue Collection for Neurodevelopmental Disabilities $830,426
University of California, San Francisco Jacquelyn Maher Tissue Collection for Disease Modeling iPSC-derived Hepatocytes as Platforms for Research in Viral Hepatitis and Non-alcoholic Steatohepatitis $791,680
University of California, San Diego James Brewer Tissue Collection for Disease Modeling Collection of skin biopsies to prepare fibroblasts from patients with Alzheimer's disease and cognitively healthy elderly controls $643,693
Cellular Dynamics International Thomas Novak hiPSC Derivation Generation and characterization of high-quality, footprint-free human induced pluripotent stem cell lines from 3,000 donors to investigate multigenic diseases $16,000,000
FUJIFILM Cellular Dynamics Deborah Requesens hPSC Repository The CIRM Human Pluripotent Stem Cell Biorepository – A Resource for Safe Storage and Distribution of High Quality iPSCs $9,942,175
Stanford University Joachim Hallmayer Tissue Collection for Disease Modeling Induced pluripotent stem cells from children with autism spectrum disorders $530,265
University of California, Los Angeles Tatiana Segura Conference 2013 Materials Research Society (MRS) Spring Meeting Symposium "Design of Cell Instructive Materials" $4,000
City of Hope, Beckman Research Institute Fouad Kandeel Conference 2013 Rachmiel Diabetes and Obesity Levine Symposium - Advances in Diabetes Research $27,750
University of California, Davis Emanual Maverakis New Faculty Physician Scientist Tunable hydrogels for therapeutic delivery of multipotent stem cells. $2,771,903
University of California, Los Angeles Ali Nsair New Faculty Physician Scientist Human Induced Pluripotent Stem Cell-Derived Cardiovascular Progenitor Cells for Cardiac Cell Therapy. $2,316,894
Children's Hospital of Los Angeles Tracy Grikscheit New Faculty Physician Scientist The generation and expansion of tissue-engineered small intestine from human stem/ progenitor cells: a preclinical study of functional translation $3,146,160
Stanford University Alan Cheng New Faculty Physician Scientist Enhancing hair cell regeneration in mouse and human inner ear $3,088,525
University of California, San Diego Mana Parast New Faculty Physician Scientist Human pluripotent stem cell-based therapeutics for preeclampsia $2,974,750
University of California, San Francisco Ophir Klein New Faculty Physician Scientist Stem cell therapy for inflammatory bowel disease $3,019,013
University of California, San Francisco Jason Pomerantz New Faculty Physician Scientist Characterization of Human Skeletal Muscle Stem Cells for Clinical Application $2,959,014
University of California, San Francisco Ann Zovein New Faculty Physician Scientist Human endothelial reprogramming for hematopoietic stem cell therapy. $2,197,683
Stanford University Michelle Monje New Faculty Physician Scientist White matter neuroregeneration after chemotherapy: stem cell therapy for “chemobrain” $2,800,526
University of California, San Francisco Tippi MacKenzie New Faculty Physician Scientist In Utero Embryonic Stem Cell Transplantation to Treat Congenital Anomalies $2,661,742
Cedars-Sinai Medical Center Robert Baloh New Faculty Physician Scientist Human iPSC modeling and therapeutics for degenerative peripheral nerve disease $3,031,737
University of California, Los Angeles Reza Ardehali New Faculty Physician Scientist Preclinical evaluation of human embryonic stem cell-derived cardiovascular progenitors in a large animal model $2,930,388
Children's Neurobiological Solutions (CNS) Foundation Alex Richmond Conference The Best Next Steps: Setting a Path for Advancing Pediatric Neurology $10,000
ViaCyte, Inc. Howard Foyt Strategic Partnership I Preclinical and clinical testing of a stem cell-based combination product for insulin-dependent diabetes $9,475,070
Vitalant Research Institute Shibani Pati Conference Cell Therapies in Trauma and Critical Care: Barriers in Translation from Pre-clinical to Clinical Development $18,440
Cedars-Sinai Medical Center Clive Svendsen Conference California ALS Summit 2012 $6,825
Gladstone Institutes, J. David Deepak Srivastava Conference ISSCR - Roddenberry International Symposium on Cellular reprogramming $43,000
Research for Cure Marilyn Smith Conference Working 2 Walk Science & Advocacy Symposium $22,113
University of California, San Francisco Ophir Klein Conference Stem Cells Craniofacial Development and Disease $4,500
Sanford Consortium for Regenerative Medicine Lawrence Goldstein Conference The Sanford Consortium for Regenerative Medicine Symposium and the investor and Partnering Forum at Stem Cells on the Mesa $44,000
University of California, Davis Alice Tarantal Conference 11th Annual Gene Therapy Symposium for Heart, Lung, and Blood Diseases $16,850
University of California, San Francisco Jeremy Reiter Basic Biology IV Modeling disease in human embryonic stem cells using new genetic tools $1,387,800
Sanford Burnham Prebys Medical Discovery Institute Huei-sheng Chen Basic Biology IV Studying Arrhythmogenic Right Ventricular Dysplasia with patient-specific iPS cells $1,579,250
Stanford University Alexander Dunn Basic Biology IV Role of mechanical signaling in stem cell self-renewal and differentiation $1,062,998
Stanford University Howard Chang Basic Biology IV Long noncoding RNAs for pluripotency and cell fate commitment $1,386,627
University of California, San Diego George Sen Basic Biology IV Regulation of Epidermal Self-Renewal and Differentiation by Histone and DNA Demethylases. $1,080,000
Gladstone Institutes, J. David Steven Finkbeiner Basic Biology IV Common molecular mechanisms in neurodegenerative diseases using patient based iPSC neurons $1,395,184
University of California, Los Angeles Kathrin Plath Basic Biology IV Understanding the status of the X chromosomes in human ESCs and preimplantation embryos $1,382,400
Gladstone Institutes, J. David Benoit Bruneau Basic Biology IV Epigenetic regulation of human cardiac differentiation $1,568,148
Gladstone Institutes, J. David Sheng Ding Basic Biology IV A new paradigm of lineage-specific reprogramming $1,568,395
University of California, San Diego Miles Wilkinson Basic Biology IV Role of the NMD RNA Decay Pathway in Maintaining the Stem-Like State $1,360,450
University of California, Los Angeles Owen Witte Basic Biology IV Trop2 dependent and independent mechanisms of self-renewal in human cancer stem cells $1,254,960
Stanford University Gerald Crabtree Basic Biology IV Mechanism and Utility of Direct Neuronal Conversion with a MicroRNA-Chromatin Switch $1,392,150
University of California, San Diego David Traver Basic Biology IV DECIPHERING THE INSTRUCTIONS FOR VERTEBRATE HSC SPECIFICATION AND AMPLIFICATION. $1,363,698
University of California, San Diego Ananda Goldrath Basic Biology IV Mechanisms to protect hESC-derived cells from allogenic immune rejection $1,160,997
Stanford University Michelle Monje Basic Biology IV Stem Cell Mechanisms Governing Discrete Waves of Gliogenesis in the Childhood Brain $1,264,248
Stanford University Roel Nusse Basic Biology IV Asymmetric stem cell division oriented by a local self-renewing signal $1,039,058
University of California, San Diego Eugene Yeo Basic Biology IV Stem cell models to analyze the role of mutated C9ORF72 in neurodegeneration $1,260,360
Cedars-Sinai Medical Center Eduardo Marbán Basic Biology IV Mechanism of heart regeneration by cardiosphere-derived cells $1,367,604
University of California, San Francisco Barbara Panning Basic Biology IV Investigation of the role of O-GlcNAcylation in SOX2 function during reprogramming $1,260,037
University of California, Berkeley Robert Tjian Basic Biology IV Transcriptional regulation of pluripotency in human embryonic stem cells $1,220,968
Stanford University Anne Brunet Basic Biology IV Energy metabolism and aging pathways in human stem cell reprogramming and differentiation $1,414,044
Stanford University Michael Cleary Basic Biology IV Prostaglandin pathway regulation of self-renwal in hematopoietic and leukemia stem cells $1,244,455
University of California, Davis Deborah Lieu Basic Biology IV Induction of Pluripotent Stem Cell-Derived Pacemaking Cells $1,333,689
University of California, San Francisco Miguel Ramalho-Santos Basic Biology IV Genetic dissection of human cellular reprogramming to pluripotency $1,184,883
City of Hope, Beckman Research Institute Yanhong Shi Basic Biology IV Modeling Alexander disease using patient-specific induced pluripotent stem cells $1,366,656
Buck Institute for Age Research Deepak Lamba Basic Biology IV 3D Modeling of Retina using Polymer Scaffolds for Understanding Disease Pathogenesis $1,212,553
University of California, San Diego Maike Sander Basic Biology IV Deciphering transcriptional control of pancreatic beta-cell maturation in vitro $1,258,560
Stanford University Judith Shizuru Disease Team Therapy Development - Research A monoclonal antibody that depletes blood stem cells and enables chemotherapy free transplants $18,990,683

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