Our Grants

CIRM provides funding across five key areas: Infrastructure, Education, Discovery Research, Translational Research, and Clinical Research. By supporting projects at every stage of development, from initial discovery to clinical trials, CIRM drives progress in regenerative medicine and accelerates innovative therapies to patients.

Check out our portfolio of awards below. Click here to see a list of People We’ve Funded. Click here to see a list of our Funded Institutions.

All CIRM Grants

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Institution Researcher name Grant Type Grant Title Award Value
Gladstone Institutes, J. David Lyandysha (Lana) Viktorovna Zholudeva Quest – Discovery Stage Research Projects Excitatory spinal interneurons from human pluripotent stem cells to treat spinal cord injury $2,942,198
University of California, Los Angeles Prof. Song Li Quest – Discovery Stage Research Projects Vax-CT to promote formation of cancer-specific T memory stem cell for personalized cancer immunotherapy $2,267,714
University of California, Los Angeles Dr. Richard Joseph Pietras Quest – Discovery Stage Research Projects Reversal of dysregulated myelopoiesis in breast cancers and cancer stem cells to boost antitumor immunotherapy $2,327,680
Greenstone Biosciences, Inc. Paul D Pang Quest – Discovery Stage Research Projects Drug Discovery for Duchenne Muscular Dystrophy Using Patient-Derived Human iPSCs $675,000
University of California, Berkeley Mr. Fyodor Urnov Quest – Discovery Stage Research Projects A Treatment for Artemis-deficient Severe Combined Immunodeficiency using Non-Viral CRISPR-driven Safe Harbor Transgenesis in Hematopoietic Stem Cells $1,809,372
University of California, Davis Aijun Wang PhD Quest – Discovery Stage Research Projects In Utero Treatment of Duchenne Muscular Dystrophy with Non-viral Gene Editing $2,035,544
Rubedo Life Sciences Inc. Marco Quarta Quest – Discovery Stage Research Projects Pharmacological regenerative treatment of idiopathic pulmonary fibrosis targeting the senescent niche of lung progenitor cells. $1,450,876
University of California, Los Angeles Dr. Gerald Lipshutz Quest – Discovery Stage Research Projects Gene Therapy for SLC6A8 Creatine Transporter Disorder $2,296,920
University of California, Los Angeles Frank Pajonk Quest – Discovery Stage Research Projects Development of novel small molecules against cancer stem cells in solid cancers $2,340,000
Lundquist Institute for Biomedical Innovation at Harbor – UCLA Medical Center Dr. Michelina Iacovino PhD Quest – Discovery Stage Research Projects A Novel Therapy for Sanfilippo B $2,297,884
Cedars-Sinai Medical Center Dmitriy Sheyn Quest – Discovery Stage Research Projects Microgel encapsulated iPSC-derived notochordal cells to treat intervertebral disc degeneration and low back pain $2,020,166
Scripps Health Dr. Darryl D. D’Lima Quest – Discovery Stage Research Projects Pluripotent Stem Cells for Tendon Tissue Engineering $2,734,163
BrainXell Therapeutics Matthew Goodus Quest – Discovery Stage Research Projects Autologous stem cell-derived interneuron cell therapy for spinal cord injury (SCI) $2,025,000
University of California, Berkeley Kevin E. Healy Quest – Discovery Stage Research Projects Novel Lipid Nanoparticles for Enhancing eNOS Synthesis for Cardioprotection Post Myocardial Infarction $2,060,248
The Scintillon Institute Brian Lawson Quest – Discovery Stage Research Projects An hematopoietic stem-cell-based approach to treat HIV employing CAR T cells and anti-HIV broadly neutralizing antibodies. $1,143,600
Nanotools Bioscience Dr. Alex Savtchenko PhD Quest – Discovery Stage Research Projects Enabling non-genetic activity-driven maturation of iPSC-derived neurons $675,000
University of California, San Diego Dr. Joseph G. Gleeson Quest – Discovery Stage Research Projects Novel antisense therapy to treat genetic forms of neurodevelopmental disease. $1,180,654
University of California, Davis Dr. Kyle D Fink PhD Quest – Discovery Stage Research Projects AAV-dCas9 Epigenetic Editing for CDKL5 Deficiency Disorder $1,413,054
CellFE Biotech Sewoon Han Tool Translational Research Projects Purpose built cell engineering for rapid manufacturing of stem-like cell therapies $934,750
Defined Bioscience, Inc. Steven Douglas Rees Tool Translational Research Projects Development of a low-cost, clinical-grade iPS maintenance medium for enabling stem cell therapy manufacturing $999,848
Stanford University Professor Irving L Weissman MD Tool Translational Research Projects Purification of Human Hematopoietic Stem Cells (HSCs) for Clinical Stem Cell Transplantation $1,347,722
HEALIOS NA, Inc. Dr. Norihiro Tsuneyoshi Tool Translational Research Projects Generation of human universal donor iPS cells $999,989
University of California, Davis Dr Jan A Nolta Tool Translational Research Projects T-Pure: Peripheral Blood Processing Tool for Point of Care CAR-T Manufacturing $1,217,954
Greenstone Biosciences, Inc. Paul D Pang Tool Translational Research Projects Cell Villages and Clinical Trial in a Dish with Pooled iPSC-CMs for Drug Discovery $1,350,000
Organos, Inc. Samuel Wall Tool Translational Research Projects Human iPSC-derived micro-heart muscles for high-throughput cardiac drug discovery $1,119,382
University of California, Davis Aijun Wang PhD Medical Device Translational Research Projects Living Synthetic Vascular Grafts with Renewable Endothelium $3,082,579
Cedars-Sinai Medical Center Yuan Yuan Diagnostic Translational Research Projects A Rapid Clinical Digital Patient-derived Organoid to Guide Breast Cancer Treatment Decision $1,535,375
University of California, Irvine Dr. Michael Demetriou Therapeutic Translational Research Projects GlyTR2 CAR T cell translation: safe pan-cancer killing via velcro-like density-dependent targeting of cancer glycans $4,581,144
University of California, San Francisco Gregory Maness Allen Therapeutic Translational Research Projects FM-IL2 CAR T cells for Pancreatic Cancer $5,644,776
Entos Pharmaceuticals John Lewis Therapeutic Translational Research Projects Lep001 – gene therapy for the treatment of congenital lipodystrophy $4,000,000
Fate Therapeutics, Inc. Martin Hosking Therapeutic Translational Research Projects Development of an off-the-shelf iPSC derived CAR T cell therapy for the treatment of solid tumors $4,000,000
Navega Therapeutics Ana Maria Moreno Therapeutic Translational Research Projects Development of an AAV Epigenetic Gene Therapy for Gain-of-Function SCN9A Disorders and Chronic Pain $3,982,633
University of California, Los Angeles Roger Hollis Therapeutic Translational Research Projects Evaluation of an ex vivo lentiviral gene therapy for the treatment of Angelman syndrome $5,276,765
ReviR Therapeutics Dr Paul R August Therapeutic Translational Research Projects Genetic Therapy Targeting mHTT mRNA and Somatic Expansion to Treat Huntington’s Disease $4,618,687
University of Southern California David D. Tran Therapeutic Translational Research Projects A Novel Gene Therapy to Target Glioblastoma via Custom-Engineered Adenovirus-Associated Viral Vectors $5,927,454
NysnoBio GT Neurology Jennifer Johnston Therapeutic Translational Research Projects Parkin Gene Therapy for Parkinson’s Disease $2,450,510
Maro Bio Akanksha Chhabra Therapeutic Translational Research Projects A novel non-genotoxic antibody conditioning therapeutic to expand access to and safety of HSCT and CD34+ gene therapies $4,043,427
Neurona Therapeutics Dr. Cory R Nicholas Therapeutic Translational Research Projects Development of a universal allogeneic human interneuron cell therapy candidate for the treatment of drug resistant focal epilepsy. $3,828,714
University of California, Los Angeles Dr. Donald B. Kohn Therapeutic Translational Research Projects Hematopoietic Stem Cell Gene Therapy for Alpha Thalassemia $5,028,351
Stanford University Natalia Gomez-Ospina Therapeutic Translational Research Projects Toward a Cure for Gaucher Disease Type 1: Autologous Transplantation of Genome Edited Hematopoietic Stem Cells $4,696,296
University of California, Los Angeles Dr. Lili Yang Therapeutic Translational Research Projects Combating Ovarian Cancer with Stem Cell-Engineered Off-The-Shelf CAR-NKT Cell Therapy $5,601,600
Axent Biosciences Inc. Rocio Sampayo Therapeutic Translational Research Projects A high quality, accessible cell therapy for Parkinson’s Disease produced in a scalable bioreactor system for 3D cell expansion and differentiation $3,999,241
AcuraStem Incorporated Mr. Samuel V. Alworth MS, MBA Therapeutic Translational Research Projects Development of AS-241, an UNC13A Targeting Antisense Oligonucleotide (ASO) Treatment for ALS, for IND-enabling Studies $4,012,325
Ray Therapeutics, INC Paul Bresge Therapeutic Translational Research Projects Optogenetic Therapy for Treatment of Geographic Atrophy $3,998,930
University of California, Los Angeles Dr. Gerald Lipshutz Therapeutic Translational Research Projects Development of a Gene Therapy for Treatment of Guanidinoacetate Methyltransferase Deficiency-Translating In Vivo Proof of Concept to Support a Pre-IND $5,145,825
University of California, San Francisco Sarah Monica Knox Therapeutic Translational Research Projects Neurogenic hydrogel stimulation of stem cells to regenerate radiation-damaged salivary glands $2,312,021
Cedars-Sinai Medical Center Dr. Ahmed Gamal Ibrahim Therapeutic Translational Research Projects Noncoding RNA drug TY1 as a therapeutic candidate for scleroderma and systemic sclerosis $2,590,224
University of California, Los Angeles Zulema Romero Garcia Therapeutic Translational Research Projects Adenine Base Editing for Autologous Hematopoietic Stem Cell Gene Therapy of CD3δ SCID $5,966,928
University of California, San Diego Dr Karen Christman Therapeutic Translational Research Projects Pro-regenerative infusible ECM biomaterial for treating acute myocardial infarction $4,353,438
University of California, Los Angeles Dr. Gerald Lipshutz Therapeutic Translational Research Projects Development of a Gene Therapy for the Treatment of Arginase Deficiency – Translating from Proof of Concept to Support Pre-IND Meeting $5,266,504

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