Our Grants

CIRM provides funding across five key areas: Infrastructure, Education, Discovery Research, Translational Research, and Clinical Research. By supporting projects at every stage of development, from initial discovery to clinical trials, CIRM drives progress in regenerative medicine and accelerates innovative therapies to patients.

Check out our portfolio of awards below. Click here to see a list of People We’ve Funded. Click here to see a list of our Funded Institutions.

All CIRM Grants

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Institution Researcher name Grant Type Grant Title Award Value
Cedars-Sinai Medical Center Cedars-Sinai Medical Center Wafa Tawackoli Research Training Grant CIRM Training Program in Translational Regenerative Medicine $5,373,075
Boston Children’s Hospital David Williams Cure Sickle Cell Initiative Clinical Trial Stage Projects Phase 2 Study of Hematopoietic Stem Cell Gene Transfer Inducing Fetal Hemoglobin in Sickle Cell Disease $8,333,581
University of California, San Francisco Mark C. Walters M.D. Cure Sickle Cell Initiative Clinical Trial Stage Projects Transplantation of CRISPR-CAS9 Corrected Hematopoietic Stem Cells (CRISPR_SCD001) in Patients with Severe Sickle Cell Disease $8,389,407
University of California, Irvine Daniela A. Bota Alpha Stem Cell Clinics Network Expansion A hub and spoke community model to equitably deliver regenerative medicine therapies to diverse populations across four California counties $8,000,000
University of Southern California Thomas Buchanan Alpha Stem Cell Clinics Network Expansion Alpha Clinic Network Expansion for Cell and Gene Therapies $7,999,983
University of California, Los Angeles Dr. Noah Carvajal Federman Alpha Stem Cell Clinics Network Expansion Expansion of the Alpha Stem Cell and Gene Therapy Clinic at UCLA $8,000,000
University of California, San Diego Dr. Catriona Jamieson Alpha Stem Cell Clinics Network Expansion UC San Diego Health CIRM Alpha Stem Cell Clinic $8,000,000
University of California, Davis Dr Mehrdad Abedi Alpha Stem Cell Clinics Network Expansion Alpha Stem Cell Clinic for Northern and Central California $7,999,997
City of Hope, Beckman Research Institute Dr. Leo D Wang Alpha Stem Cell Clinics Network Expansion The City of Hope Alpha Clinic: A roadmap for improving access to regenerative medicine therapies for all Californians $8,000,000
Cedars-Sinai Medical Center Dr. Michael I Lewis Alpha Stem Cell Clinics Network Expansion A comprehensive stem cell and gene therapy clinic to advance new therapies for a diverse patient population in California $7,957,966
University of California, San Francisco Mark C. Walters M.D. Alpha Stem Cell Clinics Network Expansion University of California, San Francisco (UCSF) Alpha Stem Cell Clinic (ASCC) $7,994,347
Stanford University Dr. Matthew H Porteus Alpha Stem Cell Clinics Network Expansion The Stanford Alpha Stem Cell Clinic $6,920,810
Generation STEAM Silvana DelPiccolo Conference – Manage The SPARK Annual Meeting Manage the 2025 Annual SPARK Conference $114,000
University of California, Irvine Dr. Aileen J Anderson Quest – Discovery Stage Research Projects Therapeutic targeting of Glioblastoma Stem Cell survival and self-renewal signaling $2,250,144
University of California, San Francisco Claire Clelland Quest – Discovery Stage Research Projects Developing a universal CRISPR gene therapy approach to treat C9orf72 ALS $2,740,592
Children’s Hospital of Los Angeles Dr Biraj Mahato Quest – Discovery Stage Research Projects Chemically engineered photoreceptors for vision restoration in retinal degeneration associated blindness. $1,711,000
University of California, Los Angeles Dr. Koki Morizono Quest – Discovery Stage Research Projects B cell receptor-mediated lentiviral expression of anti-HIV antibody $2,751,504
City of Hope, Beckman Research Institute Dr. Christine E. Brown Quest – Discovery Stage Research Projects Development of a Trifunctional Self-Renewing Memory CAR T Cell Therapy to Overcome the Heterogeneity and Suppressive Microenvironment of Glioblastoma $2,700,810
University of California, San Francisco Faranak Fattahi Quest – Discovery Stage Research Projects Drug discovery for Charcot Marie Tooth Disease using hPSC-derived Schwann cells $2,471,664
University of California, San Francisco Dr. Qizhi Tang PhD Quest – Discovery Stage Research Projects Genome editing of human Tregs to enable combinational tolerogenic therapy with T cell-targeted biologics for T1D $2,485,549
University of California, San Diego Dr. Neil Carson Chi Quest – Discovery Stage Research Projects Modulating cardiac myosin heavy chain isoform expression for treating cardiomyopathies $2,772,000
Palo Alto Veterans Institute for Research Dr Jian Luo Quest – Discovery Stage Research Projects Human induced pluripotent stem cells-derived glial enriched progenitors for the treatment of mild traumatic brain injury $2,255,189
Savanna Biotherapeutics, Inc. Dr. Sunil Gandhi Ph.D Quest – Discovery Stage Research Projects Gene-corrected human microglia for the treatment of adult onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP) $1,417,948
Palo Alto Veterans Institute for Research Irene Lorenzo Llorente Quest – Discovery Stage Research Projects Inhibitory interneurons derived from human induced pluripotent stem cells to treat stroke $2,140,122
University of Southern California Dr. Justin K Ichida Quest – Discovery Stage Research Projects Development of a VAV2 antisense oligonucleotide (ASO) treatment for ALS $2,072,560
University of California, San Francisco Faranak Fattahi Quest – Discovery Stage Research Projects Drug discovery for gastrointestinal motility disorders using hPSC-derived enteric ganglioids $1,954,367
Cedars-Sinai Medical Center Dr. Ritchie Ho Quest – Discovery Stage Research Projects C9orf72 repeat expansion-tuned allelic suppression by CRISPRi as an ALS therapy $2,274,768
Adverum Biotechnologies Inc. Cameron Keast Baker Quest – Discovery Stage Research Projects Development of an Optogenetic Vision Restoration Gene Therapy Using an Engineered Form of Melanopsin $1,150,820
University of California, Davis Ricardo Anibal Maselli MD Quest – Discovery Stage Research Projects Treatment of Myasthenic Syndrome due to Choline Acetyltransferase Deficiency Using AAV9-mediated Gene Therapy $1,500,000
Stanford University Dr. Robert Negrin MD Quest – Discovery Stage Research Projects Orthogonal IL2 Receptor Transduced Regulatory T Cells for Clinical Application $1,920,652
University of California, San Francisco Michael Wilson Quest – Discovery Stage Research Projects A First-in-Class Treatment for Progressive Multifocal Leukoencephalopathy Via Multimodal Immune System Engineering $2,182,396
Cedars-Sinai Medical Center Dr. Ke Liao Quest – Discovery Stage Research Projects RNA-based therapeutics to augment regulatory T cells: a novel approach to treat myocarditis $2,264,509
Stanford University Dr. Michael F Clarke Quest – Discovery Stage Research Projects Developing a breast cancer stem cell drug $2,053,727
University of Southern California Dr Linda Sher M.D. Quest – Discovery Stage Research Projects Assessing the Functional, Immunologic and Microbiologic Characteristics of Human Livers Created in Chimeric Pigs $2,736,590
University of California, Irvine Jianhua Yu Quest – Discovery Stage Research Projects Reprogramming Somatic Cells into iPSCs Engineered with an Anti-PSCA CAR to Develop Allogeneic Off-the-Shelf Cell Therapy to Treat Pancreatic Cancer $1,509,000
Gladstone Institutes, J. David Lyandisha Zholudeva Quest – Discovery Stage Research Projects Excitatory spinal interneurons from human pluripotent stem cells to treat spinal cord injury $2,942,198
University of California, Los Angeles Prof. Song Li Quest – Discovery Stage Research Projects Vax-CT to promote formation of cancer-specific T memory stem cell for personalized cancer immunotherapy $2,267,714
University of California, Los Angeles Dr. Richard Joseph Pietras Quest – Discovery Stage Research Projects Reversal of dysregulated myelopoiesis in breast cancers and cancer stem cells to boost antitumor immunotherapy $2,327,680
University of California, Berkeley Mr. Fyodor Urnov Quest – Discovery Stage Research Projects A Treatment for Artemis-deficient Severe Combined Immunodeficiency using Non-Viral CRISPR-driven Safe Harbor Transgenesis in Hematopoietic Stem Cells $1,809,372
University of California, Davis Aijun Wang PhD Quest – Discovery Stage Research Projects In Utero Treatment of Duchenne Muscular Dystrophy with Non-viral Gene Editing $2,035,544
Rubedo Life Sciences Inc. Marco Quarta Quest – Discovery Stage Research Projects Pharmacological regenerative treatment of idiopathic pulmonary fibrosis targeting the senescent niche of lung progenitor cells. $1,450,876
University of California, Los Angeles Dr. Gerald Lipshutz Quest – Discovery Stage Research Projects Gene Therapy for SLC6A8 Creatine Transporter Disorder $2,296,920
University of California, Los Angeles Frank Pajonk Quest – Discovery Stage Research Projects Development of novel small molecules against cancer stem cells in solid cancers $2,340,000
Cedars-Sinai Medical Center Dmitriy Sheyn Quest – Discovery Stage Research Projects Microgel encapsulated iPSC-derived notochordal cells to treat intervertebral disc degeneration and low back pain $2,020,166
Scripps Health Dr. Darryl D. D’Lima Quest – Discovery Stage Research Projects Pluripotent Stem Cells for Tendon Tissue Engineering $2,734,163
Lundquist Institute for Biomedical Innovation at Harbor – UCLA Medical Center Dr. Michelina Iacovino PhD Quest – Discovery Stage Research Projects A Novel Therapy for Sanfilippo B $2,297,884
BrainXell Therapeutics, Inc. Matthew Goodus Quest – Discovery Stage Research Projects Autologous stem cell-derived interneuron cell therapy for spinal cord injury (SCI) $2,025,000
University of California, Berkeley Kevin E. Healy Quest – Discovery Stage Research Projects Novel Lipid Nanoparticles for Enhancing eNOS Synthesis for Cardioprotection Post Myocardial Infarction $2,060,248
CellFE Biotech Sewoon Han Tool Translational Research Projects Purpose built cell engineering for rapid manufacturing of stem-like cell therapies $934,750
Stanford University Professor Irving L Weissman MD Tool Translational Research Projects Purification of Human Hematopoietic Stem Cells (HSCs) for Clinical Stem Cell Transplantation $1,347,722
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