Funding Opportunities for Infrastructure Projects


The mission of California Institute for Regenerative Medicine (CIRM) is to accelerate world class science to deliver transformative regenerative medicine treatments in an equitable manner to a diverse California and world. In December 2021, CIRM released its Strategic Plan for 2022-2027. The Strategic Plan describes CIRM’s Infrastructure Programs which are designed to address the challenges that currently hinder progress in the regenerative medicine field.

INFR 6: Shared Resources Laboratories for Stem Cell-Based Modeling

The Shared Resources Laboratories (SRL) for Stem Cell-Based Modeling program intends to accelerate regenerative medicine research by creating a network of SRLs that 1) broaden access to stem cell-based models across CA, 2) advance standards and reproducibility of stem cell-based models, 3) increase access to educational opportunities in stem cell-based techniques, and 4) develop sustainable stem cell core infrastructure.

The program intends to fund two different types of SRLs that will be solicited through two separate requests for applications (RFAs): 1) Establishing (E)-SRLs to provide local access to stem cell-based models, training, specialized equipment, and educational opportunities in geographic areas/locations where access to models is limited; and 2) Enhancing / Expanding (E/E)-SRLs to enable leading experts in stem cell-based modeling to share their models and expertise locally and broadly across California. CIRM expects SRLs to become self-sustaining by the end of the award period.

Please see the INFR 6.1 RFA for full details:

Please see the INFR 6.2 RFA for full details:

Watch a video recording of our INFR6 Shared Resources Laboratories for Stem Cell-Based Modeling webinar from June 27, 2023. The slide deck is available here and a webinar Q&A document is available here.

The applications for Shared Resource Laboratories are closed.

INFR 8: CIRM Community Care Centers of Excellence (CCCEs)

The objective of this funding opportunity is to establish geographically diverse and culturally responsive centers of excellence to (1) support access to FDA-authorized clinical trials involving cell, gene, and/or approved regenerative medicine treatments, (2) make these treatments broadly available to California patients, and (3) provide workforce career development opportunities. The CCCEs will work in partnership with the Clinical Infrastructure Network and other CIRM programs to expand equitable access to communities and populations that would otherwise have more limited opportunities in the absence of these centers.

Please see the INFR 8 RFA for full details:

Applications for Community Care Centers of Excellence are available in the grants management portal. Applications are due by 2 PM on August 15, 2024.

CCCEs Informational Webinars
The CIRM Patient Access team, on May 15, 2024, and July 2, 2024, hosted informational webinars that reviewed CIRM’s Clinical Infrastructure Network, eligibility requirements, and review process and included a Q&A session. 

To Submit an Application:

  1. Go to the Grants Management Portal ( and log in with your existing CIRM Username and Password. If you do not have a Username, Click on the “New User” link and follow the instructions to create a CIRM Username and password.
  2. After logging in, Click on the Menu tab. Select the tab labeled “Open Programs“. Under the section labeled “RFAs and Programs Open for Applications“, click on the applicable link to “Start an INFR Application“.
  3. Complete each section of the Application by clicking on the appropriate link and following the posted instructions. Proposal templates can be located and submitted under the “Uploads” section.
  4. To submit your Application, click on the “Done with Application” button. The “Done with Application” button will be enabled when all of the mandatory sections have been completed. Please note that once this has been selected, you will no longer be able to make changes to your Application.
  5. To confirm submission of your Application, select the tab labeled “Your Applications” and check the table under the section labeled “Your Submitted Applications“. You will see your Application number and project title listed once the submission process has been completed.

For more information on the programs and buildings we’ve funded, check out our Program and Building Infrastructure Page.