All CIRM Grants

Institution Researcher name Grant Type Grant Title Award Value
University of California, Los Angeles Benhur Lee Basic Biology II The EphrinB2/EphB4 axis in regulating hESC pluripotency and differentiation $1,371,936
Scripps Health Darryl D'Lima Preclinical Development Awards Embryonic Stem Cell-Derived Chondroprogenitor Cells to Repair Osteochondral Defects $7,660,211
City of Hope Jiing-Kuan Yee Basic Biology III Use of human iPS cells to study spinal muscular atrophy $1,268,868
University of California, Irvine Leslie Thompson Disease Team Planning Huntington's Disease Team $41,953
Scripps Research Institute Kristin Baldwin New Faculty I Generating pluripotent cell lines from neurons. $2,786,560
Sanford-Burnham Medical Research Institute Robert Wechsler-Reya Research Leadership The role of neural stem cells in cerebellar development, regeneration and tumorigenesis $5,226,050
Numerate, Inc. John Griffin Early Translational IV Use of human iPSC-derived neurons from Huntington’s Disease patients to develop novel, disease-modifying small molecule structural corrector drug candidates targeting the unique, neurotoxic conformation of mutant huntingtin $520,015
Buck Institute for Age Research Xianmin Zeng Shared Labs CIRM Shared Research Laboratory for Stem Cells and Aging $3,478,933
Salk Institute for Biological Studies Samuel Pfaff SEED Grant Gene regulatory mechanisms that control spinal neuron differentiation from hES cells. $704,543
Children's Hospital of Orange County Philip Schwartz Early Translational III Immune-Matched Neural Stem Cell Transplantation for Pediatric Neurodegenerative Disease $4,272,774
Scripps Research Institute Peter Schultz Early Translational II Cartilage Regeneration by the Chondrogenic Small Molecule PRO1 during Osteoarthritis $6,047,249
Geron Corporation Jane Lebkowski Targeted Clinical Development Evaluation of Safety and Preliminary Efficacy of Escalating Doses of GRNOPC1 in Subacute Spinal Cord Injury $6,405,771
University of California, Riverside Prudence Talbot Shared Labs A Stem Cell Core Facility for Studying Human Embryonic Stem Cell Differentiation $1,976,931
Fluidigm Corporation Marc Unger Tools and Technologies II Development and Application of Versatile, Automated, Microfluidic Cell Culture System $1,939,236
Sangamo BioSciences, Inc. Fyodor Urnov Strategic Partnership II A Treatment For Beta-thalassemia via High-Efficiency Targeted Genome Editing of Hematopoietic Stem Cells $2,760,540
Stanford University Helen Blau Tools and Technologies I Regulation of Stem Cell Fate in Bioengineered Arrays of Hydrogel Microwells $949,608
University of California, San Diego Shu Chien SEED Grant Combinatorial Platform for Optimizing Microenvironments to Control hESC Fate $577,148
Capricor, Inc Rachel Smith Disease Team Therapy Development - Research Allogeneic Cardiac-Derived Stem Cells for Patients Following a Myocardial Infarction $19,782,136
ViaCyte, Inc. Allan Robins Disease Team Research I Cell Therapy for Diabetes $22,999,933
Children's Hospital of Los Angeles David Warburton Research Training II Stem Cell Training Grant $5,020,920
City of Hope John Zaia Strategic Partnership III Track A A Phase I, Open-Label Study to Assess the Safety, Feasibility and Engraftment of Zinc Finger Nucleases (ZFN) CCR5 Modified Autologous CD34+ Hematopoietic Stem/Progenitor Cells with Escalating Doses of Busulfan in HIV-1 (R5) Infected Subjects with Suboptim $5,583,438
Stanford University Helen Blau Basic Biology V Mass Cytometry to Delineate the Human Muscle Stem Cell Hierarchy and Dysfunction in Aging $1,175,357
University of California, Davis Kit Lam Tools and Technologies I Discovery of adhesion ligands for pluripotent human stem cells $834,003
University of California, Los Angeles Brigitte Gomperts New Faculty II Stem Cells in Lung Cancer $2,381,572
University of California, Berkeley Robert Tjian Basic Biology IV Transcriptional regulation of pluripotency in human embryonic stem cells $1,220,968
San Diego State University Ricardo Zayas New Faculty II The molecular basis underlying adult neurogenesis during regeneration and tissue renewal $1,712,225
Gladstone Institutes Robert Farese New Cell Lines Establishment of Frontotemporal Dementia Patient-Specific Induced Pluripotent Stem (iPS) Cell Lines with Defined Genetic Mutations $1,696,424
San Jose State University Tzvia Abramson Bridges Stem Cell Internships for Laboratory-based Learning (SCILL) $4,189,957
University of California, Los Angeles John Adams Alpha Stem Cell Clinics Alpha Stem Cell Clinic (ASCC) Consortium $8,000,000
Palo Alto Institute for Research and Education Thomas Rando Basic Biology V Molecular regulation of stem cell potency $966,510
University of California, San Diego Martin Marsala Transplantation Immunology Induction of immune tolerance after spinal grafting of human ES-derived neural precursors $1,387,800
Stanford University Paul Utz Creativity Awards [REDACTED] Program: Stem Cell & Developmental Biology Research Internships $348,037
University of California, San Francisco Samuel Pleasure Comprehensive Grant Human stem cell derived oligodendrocytes for treatment of stroke and MS $2,459,235
University of California, Irvine Grant MacGregor SEED Grant Production of Oocytes from Human ES Cells $385,466
University of California, Davis Nancy Lane Disease Team Therapy Planning I Increasing the endogenous mesenchymal stem cells to the bone surface to treat osteoporosis $107,750
Stanford University Susan McConnell Basic Biology I Identification and characterization of human ES-derived DA neuronal subtypes $1,404,853
Stanford University Sarah Heilshorn Tools and Technologies III Injectable Hydrogels for the Delivery, Maturation, and Engraftment of Clinically Relevant Numbers of Human Induced Pluripotent Stem Cell-Derived Neural Progenitors to the Central Nervous System $1,347,767
University of Southern California Chrysostomos Nikias Major Facilities Broad CIRM Facility at USC $26,972,500
Gladstone Institutes Sheng Ding New Faculty I Reprogramming of human somatic cells back to pluripotent embryonic stem cells $1,320,101
University of California, San Francisco Ann Zovein New Faculty Physician Scientist Human endothelial reprogramming for hematopoietic stem cell therapy. $2,319,784
Scripps Research Institute Jeanne Loring Early Translational I Ensuring the safety of cell therapy: a quality control pipeline for cell purification and validation $5,830,771
Gladstone Institutes Fen-Biao Gao SEED Grant MicroRNAs in Human Stem Cell Differentiation and Mental Disorders $748,800
California Institute of Technology Paul Patterson Training Grant I-2 Training in Stem Cell Biology at CIT $1,817,214
Stanford University Aaron Hsueh Basic Biology II Maturation of Human Oocytes for SCNT and Embryonic Stem Cell Derivation $1,309,018
Stanford University Matthew Porteus Preclinical Development Awards Pre-clinical development of gene correction therapy of hematopoietic stem cells for SCID-X1 $874,877
University of California, Berkeley Song Li Basic Biology III Induced Pluripotent Stem Cells for Tissue Regeneration $1,209,148
Children's Hospital of Los Angeles Donald Kohn Disease Team Planning STEM CELL GENE THERAPY FOR SICKLE CELL DISEASE $12,131
Stanford University Michele Calos Tools and Technologies II Site-specific integration of Lmx1a, FoxA2, & Otx2 to optimize dopaminergic differentiation $1,592,897
Sanford-Burnham Medical Research Institute Stuart Lipton Early Translational IV Programming Human ESC-derived Neural Stem Cells with MEF2C for Transplantation in Stroke $1,020,815
Scripps Research Institute Jeanne Loring Shared Labs Center for hESC Research $3,725,070
University of California, Los Angeles Michael Teitell SEED Grant Role of Mitochondria in Self-Renewal Versus Differentiation of Human Embryonic Stem Cells $543,274
University of California, San Diego Yang Xu Early Translational III Human ES cell based therapy of heart failure without allogenic immune rejection $1,857,600
iPierian, Inc. John Dimos Early Translational II New Drug Discovery for SMA using Patient-derived Induced Pluripotent Stem Cells $2,410,000
City of Hope Michael Barish Research Training II Research Training Program in Stem Cell Biology $2,500,143
Scripps Research Institute Jeanne Loring Shared Labs Collaborative Laboratory for Human Embryonic Stem Cell Research $1,361,825
TriFoil Imaging, Inc. Joann Zhang Tools and Technologies II Tri-resolution Visualization System for Stem Cells and Tissue Regeneration Monitoring $1,456,989
University of California, San Diego Thomas Kipps Disease Team Therapy Development III Therapeutic Eradication of Cancer Stem Cells $4,179,598
VistaGen Therapeutics, Inc. Kristina Bonham Tools and Technologies I Development of an hES Cell-Based Assay System for Hepatocyte Differentiation Studies and Predictive Toxicology Drug Screening $971,558
Salk Institute for Biological Studies Senyon Choe SEED Grant A method to maintain and propagate pluripotent human ES cells $760,042
University of California, Irvine Henry Klassen Disease Team Therapy Development - Research Retinal progenitor cells for treatment of retinitis pigmentosa $17,144,825
Cedars-Sinai Medical Center Eduardo Marbán Disease Team Research I Autologous cardiac-derived cells for advanced ischemic cardiomyopathy $5,560,232
University of California, Los Angeles Kenneth Dorshkind Research Training II CIRM Research Training Program II $7,790,488
University of California, Berkeley Xavier Darzacq Research Leadership Single Molecule Biophysics and Biology of Cellular Identity $4,255,167
Salk Institute for Biological Studies Ronald Evans Basic Biology V Metabolically-driven epigenetic changes in iPSC reprogramming $1,491,900
Scripps Research Institute Carlos Barbas Tools and Technologies I Development of a novel technology for precise, efficient, and safe genetic modification of stem cells $1,138,548
Ludwig Institute for Cancer Research Bing Ren New Faculty II Mechanisms of chromatin dynamics at enhancers during ES cell differentiation $1,726,564
Stanford University Anne Brunet Basic Biology IV Energy metabolism and aging pathways in human stem cell reprogramming and differentiation $1,414,044
Sanford-Burnham Medical Research Institute Stuart Lipton Comprehensive Grant MEF2C-Directed Neurogenesis From Human Embryonic Stem Cells $2,832,000
Salk Institute for Biological Studies Fred Gage New Cell Lines Development of Induced Pluripotent Stem Cells for Modeling Human Disease $1,737,720
Berkeley City College Barbara Des Rochers Bridges Specialty in Stem Cell Biology $2,558,105
City of Hope John Zaia Alpha Stem Cell Clinics The Innovation-Alpha Clinic for Cellular Therapies (I-ACT) – A Program for the Development and Delivery of Innovative Cell-based Treatments and Cures for Life-threatening Diseases. $8,000,000
University of California, Merced Kara McCloskey Basic Biology V Directed Differentiation of Specialized Endothelial Cells $476,052
University of California, Davis William Murphy Transplantation Immunology Donor natural killer (NK) cells as “veto” cells to promote donor-specific tolerance $1,257,601
Children's Hospital of Oakland Research Institute Vasanthy Narayanaswami Creativity Awards [REDACTED] Summer Stem Cell Research Internship Program for High School Students $151,046
University of California, Los Angeles Zack Jerome Comprehensive Grant Human Embryonic Stem Cell Therapeutic Strategies to Target HIV Disease $2,401,903
University of California, Riverside Michael Pirrung SEED Grant Stem Cell Survival and Differentiation Through Chemical Genetics $522,933
University of California, Davis Martin Birchall Disease Team Therapy Planning I Airways for Children $19,800
University of California, San Diego Eugene Yeo Basic Biology I RNA Binding Protein-mediated Post-transcriptional Networks Regulating HPSC Pluripotency $1,308,901
University of California, Irvine Mathew Blurton-Jones Tools and Technologies III Optimizing the differentiation and expansion of microglial progenitors from human pluripotent stem cells for the study and treatment of neurological disease. $1,147,596
University of California, San Francisco Jeffrey Bluestone Disease Team Planning A CIRM Disease Team for the Treatment and Cure of Diabetes $55,000
Western University of Health Sciences Douglas Ethell New Faculty I ES-Derived Cells for the Treatment of Alzheimer's Disease $1,401,642
Stanford University Michelle Monje New Faculty Physician Scientist White matter neuroregeneration after chemotherapy: stem cell therapy for “chemobrain” $2,800,536
ViaCyte, Inc. Olivia Kelly Early Translational I Methods for detection and elimination of residual human embryonic stem cells in a differentiated cell product $5,405,397
University of California, Los Angeles Noriyuki Kasahara SEED Grant Down-Regulation of Alloreactive Immune Responses to hES Cell-Derived Graft Tissues $399,239
University of California, Santa Cruz David Haussler Training Grant I-3 Training Program in Systems Biology of Stem Cells $1,133,701
Salk Institute for Biological Studies Ronald Evans Basic Biology II Molecular Characterization and Functional Exploration of Nuclear Receptors in hiPSCs $1,712,880
Cedars-Sinai Medical Center Shaomei Wang Late Stage Preclinical Projects IND-enabling study of subretinal delivery of human neural progenitor cells for the treatment of retinitis pigmentosa $4,954,514
University of California, Los Angeles Ali Nsair Basic Biology III Characterization and Engineering of the Cardiac Stem Cell Niche $1,127,741
Sanford-Burnham Medical Research Institute Mark Mercola Disease Team Planning "Stem Cell Therapies for Heart Failure" $44,450
City of Hope Michael Barish Disease Team Planning Genetically-modified neural stem cells for treatment of high-grade glioma $55,000
University of California, Los Angeles Stanley Carmichael Tools and Technologies II Development of a Hydrogel Matrix for Stem Cell Growth and Neural Repair after Stroke $1,825,613
Stanford University Michele Calos Early Translational IV Engineered iPSC for therapy of limb girdle muscular dystrophy type 2B $1,876,253
University of California, Davis Alice Tarantal Shared Labs Translational Human Embryonic Stem Cell Shared Research Facility $1,728,111
Stanford University Thomas Wandless SEED Grant Reprogramming Differentiated Human Cells to a Pluripotent State $380,005
University of California, San Francisco Holger Willenbring Early Translational III Generation of safe and therapeutically effective human induced hepatocyte-like cells $1,544,170
University of California, Davis Early Translational II Bone Marrow Mesenchymal Stem Cells to Heal Chronic Diabetic Wounds $4,635,576
University of California, Santa Barbara Dennis Clegg Research Training II Training Program in Stem Cell Biology and Engineering $2,448,823
Gladstone Institutes Deepak Srivastava Shared Labs CIRM Shared Human Embryonic Stem Cell Core Laboratory $842,672
Stanford University Irving Weissman Tools and Technologies II Antibody tools to deplete or isolate teratogenic, cardiac, and blood stem cells from hESCs $1,463,814
Stanford University Irving Weissman Disease Team Therapy Development III Clinical Investigation of a Humanized Anti-CD47 Antibody in Targeting Cancer Stem Cells in Hematologic Malignancies and Solid Tumors $11,650,152