All CIRM Grants

Institution Researcher name Grant Type Grant Title Award Value
University of California, San Francisco Jason Pomerantz Basic Biology III Phenotypic Analysis of Human ES Cell-Derived Muscle Stem Cells $1,381,296
BioTime, Inc. Michael West Early Translational I Addressing the Cell Purity and Identity Bottleneck Through Generation and Expansion of Clonal Human Embryonic Progenitor Cell Lines $4,721,706
Buck Institute for Age Research Xianmin Zeng Disease Team Planning Develop a cell replacement therapy for Parkinson's disease using human embryonic stem cells $37,161
Salk Institute for Biological Studies Senyon Choe SEED Grant A method to maintain and propagate pluripotent human ES cells $760,042
University of California, San Francisco Jacquelyn Maher Tissue Collection for Disease Modeling iPSC-derived Hepatocytes as Platforms for Research in Viral Hepatitis and Non-alcoholic Steatohepatitis $814,976
Cedars-Sinai Medical Center Eduardo Marbán Disease Team Research I Autologous cardiac-derived cells for advanced ischemic cardiomyopathy $5,560,232
University of California, Davis Walter Boyd Early Translational III Extracellular Matrix Bioscaffold Augmented with Human Stem Cells for Cardiovascular Repair $4,633,149
University of California, Los Angeles Martin Martin Tools and Technologies II Pluripotent and Somatic Stem Cell Models to Study Inherited Diarrheal Disorders $1,783,250
University of California, Los Angeles William Lowry Basic Biology III Molecular determinants of accurate differentiation from human pluripotent stem cells $677,115
University of California, Santa Barbara Dennis Clegg Shared Labs Laboratory for Stem Cell Biology and Engineering $1,638,357
Buck Institute for Age Research Xianmin Zeng Shared Labs CIRM Shared Research Laboratory for Stem Cells and Aging $2,414,749
Ludwig Institute for Cancer Research Bing Ren New Faculty II Mechanisms of chromatin dynamics at enhancers during ES cell differentiation $1,726,564
Cedars-Sinai Medical Center Dan Gazit Early Translational IV Gene Targeting to Endogenous Stem Cells for Segmental Bone Fracture Healing $5,180,674
Salk Institute for Biological Studies Fred Gage New Cell Lines Development of Induced Pluripotent Stem Cells for Modeling Human Disease $1,737,720
University of California, Los Angeles Antoni Ribas Disease Team Therapy Development - Research Genetic Re-programming of Stem Cells to Fight Cancer $19,875,776
University of California, Irvine Mathew Blurton-Jones Tools and Technologies III Optimizing the differentiation and expansion of microglial progenitors from human pluripotent stem cells for the study and treatment of neurological disease. $1,147,596
Gladstone Institutes Robert Mahley Research Training II CIRM Scholars Program $4,945,955
University of California, San Diego Steve Dowdy Tools and Technologies I TAT Cell-Permeable Protein Delivery of siRNAs for Epigenetic Programming of Human Pluripotent and Adult Stem Cells $720,000
Cedars-Sinai Medical Center Terrence Town Transplantation Immunology Role of HLA in neural stem cell rejection using humanized mice $1,119,385
University of California, San Diego Mana Parast New Faculty II Molecular Mechanisms of Trophoblast Stem Cell Specification and Self-Renewal $3,077,918
Stanford University Xinnan Wang Basic Biology V Misregulated Mitophagy in Parkinsonian Neurodegeneration $1,174,943
University of California, Riverside Michael Pirrung SEED Grant Stem Cell Survival and Differentiation Through Chemical Genetics $522,933
University of California, San Diego Miles Wilkinson Basic Biology IV Role of the NMD RNA Decay Pathway in Maintaining the Stem-Like State $1,360,450
University of California, San Diego Eugene Yeo Basic Biology I RNA Binding Protein-mediated Post-transcriptional Networks Regulating HPSC Pluripotency $1,308,901
Cedars-Sinai Medical Center Shaomei Wang Late Stage Preclinical Projects IND-enabling study of subretinal delivery of human neural progenitor cells for the treatment of retinitis pigmentosa $4,954,514
California State University, San Marcos Bianca Mothe Bridges CIRM Bridges to the Stem Cell Research Training Grant $4,114,712
Palo Alto Institute for Research and Education Husein Hadeiba Transplantation Immunology Application of Tolerogenic Dendritic Cells for Hematopoietic Stem Cell Transplantation $733,061
University of California, Los Angeles Sophie Deng Early Translational II Regeneration of Functional Human Corneal Epithelial Progenitor Cells $697,507
University of California, San Diego Yang Xu Comprehensive Grant Mechanisms to maintain the self-renewal and genetic stability of human embryonic stem cells $2,467,200
Stanford University Gary Steinberg Basic Biology V Paracrine and synaptic mechanisms underlying neural stem cell-mediated stroke recovery $1,178,370
University of California, Los Angeles Noriyuki Kasahara SEED Grant Down-Regulation of Alloreactive Immune Responses to hES Cell-Derived Graft Tissues $399,239
Gladstone Institutes Sheng Ding Basic Biology IV A new paradigm of lineage-specific reprogramming $1,708,560
Salk Institute for Biological Studies Ronald Evans Basic Biology II Molecular Characterization and Functional Exploration of Nuclear Receptors in hiPSCs $1,712,880
Stanford University Albert Wong Disease Team Therapy Planning I Recombinant Bispecific Antibody Targeting Cancer Stem Cells for the Therapy of Glioblastoma $109,750
Stanford University Howard Chang New Faculty I Noncoding RNAs in Cell Fate Determination $2,985,894
University of California, Santa Cruz Bin Chen New Faculty I Molecular mechanisms of neural stem cell differentiation in the developing brain $2,147,592
University of California, Los Angeles James Dunn Tools and Technologies III Skin-derived precursor cells for the treatment of enteric neuromuscular dysfunction $1,818,751
University of California, Davis Jan Nolta Early Translational I Sustained siRNA production from human MSC to treat Huntingtons Disease and other neurodegenerative disorders $2,615,674
University of California, Los Angeles Gene Block Major Facilities UCLA CIRM Institute $19,854,900
Stanford University Thomas Wandless SEED Grant Reprogramming Differentiated Human Cells to a Pluripotent State $380,005
Children's Hospital of Los Angeles Tracy Grikscheit New Faculty Physician Scientist The generation and expansion of tissue-engineered small intestine from human stem/ progenitor cells: a preclinical study of functional translation $3,146,160
University of California, Davis Early Translational II Bone Marrow Mesenchymal Stem Cells to Heal Chronic Diabetic Wounds $4,635,576
University of California, Irvine Peter Bryant Training Grant I-1 Stem Cell Research Training Grant $1,935,487
Salk Institute for Biological Studies Lei Wang New Faculty I Genetic Encoding Novel Amino Acids in Embryonic Stem Cells for Molecular Understanding of Differentiation to Dopamine Neurons $2,587,742
University of California, Los Angeles Yi Sun Basic Biology III Studying neurotransmission of normal and diseased human ES cell-derived neurons in vivo $1,382,400
University of Southern California Martin Pera New Cell Lines New Technology ForThe Derivation of Human Pluripotent Stem Cell Lines For Clinical Use $1,266,134
University of California, Irvine Henry Klassen Disease Team Planning Stem cells for neuroprotection of photoreceptors in retinitis pigmentosa $23,537
Sanford-Burnham Medical Research Institute Gregg Duester SEED Grant Retinoic Acid-FGF Antagonism during Motor Neuron Differentiation of Human ES Cells $695,229
University of California, San Diego Douglas Galasko Tissue Collection for Disease Modeling Collection of skin biopsies to prepare fibroblasts from patients with Alzheimer's disease and cognitively healthy elderly controls $643,693
City of Hope John Zaia Disease Team Research I ZIinc Finger Nuclease-Based Stem Cell Therapy for AIDS $14,536,969
University of California, San Diego Eric Adler Early Translational III Identification of Novel Therapeutics for Danon Disease Using an iPS Model of the Disease $1,701,575
Stanford University Brian Rutt Tools and Technologies II Development of Single Cell MRI Technology using Genetically-Encoded Iron-Based Reporters $1,833,348
University of California, Los Angeles Shuo Lin Basic Biology III Etsrp/ER71 mediated stem cell differentiation into vascular lineage $1,382,400
University of California, San Diego Karl Willert Shared Labs Enhancing Facilities for Genetic Manipulation and Engineering of Human Embryonic Stem Cells $1,737,694
Gladstone Institutes Sheng Ding Shared Labs Center for hESC Research $1,440,164
University of California, San Diego Shyni Varghese New Faculty II A Novel Microenvironment-Mediated Functional Skeletal Muscle from Human Embryonic Stem Cells and their In Vivo Engraftment $2,300,569
University of California, San Diego Alysson Muotri Early Translational IV A drug-screening platform for autism spectrum disorders using human astrocytes $1,656,456
University of California, San Francisco Long-cheng Li New Cell Lines Induction of pluripotent stem cells by small RNA-guided transcriptional activation $1,368,461
University of California, Davis John Laird Disease Team Therapy Development - Research Phase I study of IM Injection of VEGF-Producing MSC for the Treatment of Critical Limb Ischemia $3,728,384
Stanford University Irving Weissman Tools and Technologies III Identification and isolation of transplantable human hematopoietic stem cells from pluripotent cell lines; two steps from primitive hematopoiesis to transplantable definitive cells, and non-toxic conditioning of hosts for hematopoeitic stem cell transplan $1,341,403
University of Southern California Robert Maxson Research Training II CIRM Stem Cell Biology Training Program $6,162,045
University of California, Irvine Lisa Flanagan Tools and Technologies I Novel Separation of Stem Cell Subpopulations $861,122
Scripps Research Institute Sheng Ding New Faculty I Reprogramming of human somatic cells back to pluripotent embryonic stem cells $1,393,876
University of California, San Francisco Ophir Klein New Faculty II Laying the groundwork for building a tooth: analysis of dental epithelial stem cells $3,075,251
University of California, Los Angeles Lili Yang Basic Biology V Differentiation of Human Hematopoietic Stem Cells into iNKT Cells $614,400
Sanford-Burnham Medical Research Institute Huei-sheng Chen SEED Grant Development of Neuro-Coupled Human Embryonic Stem Cell-Derived Cardiac Pacemaker Cells. $695,680
Stanford University Gerald Crabtree Basic Biology IV Mechanism and Utility of Direct Neuronal Conversion with a MicroRNA-Chromatin Switch $1,392,426
Stanford University Julien Sage Basic Biology I The retinoblastoma (RB) gene family in cellular reprogramming $1,357,085
Caladrius Biosciences, Inc. Robert Dillman Clinical Trial Stage Projects Tumor stem cell-targeted immunotherapy for metastatic melanoma –a randomized phase 3 clinical trial. $3,000,000
City College Of San Francisco Carin Zimmerman Bridges Stem Cell Training Enhancement Program $2,704,836
Escape Therapeutics, Inc Basil Hantash Transplantation Immunology Development of an immune tolerant hESC source for allogeneic cell therapy applications $1,453,040
University of California, San Diego Catriona Jamieson SEED Grant Derivation and Characterization of Cancer Stem Cells from Human ES Cells $616,305
Stanford University Julie Baker Comprehensive Grant Functional Genomic Analysis of Chemically Defined Human Embryonic Stem Cell $2,518,303
California Institute of Technology David Tirrell Basic Biology V Engineered matrices for control of lineage commitment in human pancreatic stem cells $526,896
University of California, San Francisco Heike Daldrup-Link SEED Grant Labeling of human embryonic stem cells with iron oxide nanoparticles and fluorescent dyes for a non-invasive cell depiction with MR imaging and optical imaging $240,214
University of California, Los Angeles Owen Witte Basic Biology IV Trop2 dependent and independent mechanisms of self-renewal in human cancer stem cells $1,254,960
iPierian, Inc. Irene Griswold-Prenner Basic Biology II Cellular Reprogramming: Dissecting the Molecular Mechanism and Enhancing Efficiency $1,458,000
Samumed, LLC John Hood Disease Team Therapy Planning I Clinical Development of an osteoinductive therapy to prevent osteoporosis-related fractures $99,110
University of California, Berkeley Irina Conboy New Faculty I Identification of hESC-mediated molecular mechanism that positively regulates the regenerative capacity of post-natal tissues $2,246,020
University of California, Davis J. Leach Tools and Technologies III Multi-modal technology for non-destructive characterization of bioengineered tissues $1,842,792
University of California, Irvine Frank LaFerla Early Translational I Neural Stem Cells as a Developmental Candidate to Treat Alzheimer Disease $3,599,997
University of California, Merced John White Major Facilities Stem Cell Instrumentation Foundry $4,341,321
Stanford University Kenneth Weinberg SEED Grant Embryonic stem cell-derived thymic epithelial cells $628,793
Stanford University Alan Cheng New Faculty Physician Scientist Enhancing hair cell regeneration in mouse and human inner ear $3,091,595
University of California, San Francisco Markus Muschen Early Translational II Dual targeting of tyrosine kinase and BCL6 signaling for leukemia stem cell eradication $2,756,536
Scripps Research Institute Peter Schultz Training Grant I-2 Training Grant I $1,021,395
Stanford University Joanna Wysocka New Faculty I Trithorax and Polycomb methyltransferase complexes in cell fate determination. $2,373,903
Stanford University Michael Clarke Basic Biology III USP16 controls stem cell number: implications for Down Syndrome $1,263,826
Ludwig Institute for Cancer Research Webster Cavenee Disease Team Planning Stem Cell-Mediated Oncocidal Therapy of Primary & Metastatic Brain Tumors $3,867
Sanford-Burnham Medical Research Institute Zhuohua Zhang SEED Grant Modeling Parkinson's Disease Using Human Embryonic Stem Cells $701,060
Cellular Dynamics International Thomas Novak hiPSC Derivation Generation and characterization of high-quality, footprint-free human induced pluripotent stem cell lines from 3,000 donors to investigate multigenic diseases $16,000,000
University of California, Los Angeles Irvin Chen Disease Team Research I HPSC based therapy for HIV disease using RNAi to CCR5. $9,905,604
University of Southern California Toshio Miki Early Translational III Generation of hepatic cell from placental stem cell for congenital metabolic disorders $1,750,375
University of California, Berkeley David Schaffer Tools and Technologies II Engineering Defined and Scaleable Systems for Dopaminergic Neuron Differentiation of hPSCs $1,340,816
Scripps Research Institute Kristin Baldwin Basic Biology III Identifying sources of mutation in human induced pluripotent stem cells by whole genome sequencing $1,705,500
University of California, San Francisco Linda Giudice Shared Labs Shared Research and Teaching Laboratory: a Non-Federal Human Embryonic Stem Cell Resource for the Bay Area Community $3,289,649
University of California, Davis Alice Tarantal Shared Labs Translational Human Embryonic Stem Cell Shared Research Facility $2,000,000
University of California, San Francisco Robert Blelloch New Faculty II Mechanisms of small RNA regulation in early embryonic development $2,790,695
Gladstone Institutes Steven Finkbeiner Early Translational IV Development of Novel Autophagy Inducers to Block the Progression of and Treat Amyotrophic Lateral Sclerosis (ALS) and Other Neurodegenerative Diseases $2,278,080