All CIRM Grants

Institution Researcher name Grant Type Grant Title Award Value
Children's Hospital of Orange County Philip Schwartz Early Translational III Immune-Matched Neural Stem Cell Transplantation for Pediatric Neurodegenerative Disease $4,272,774
University of California, Irvine Henry Klassen Disease Team Therapy Development - Research Retinal progenitor cells for treatment of retinitis pigmentosa $17,144,825
Stanford University Anne Brunet Basic Biology IV Energy metabolism and aging pathways in human stem cell reprogramming and differentiation $1,414,044
Stanford University Alan Cheng New Faculty Physician Scientist Enhancing hair cell regeneration in mouse and human inner ear $3,091,595
Cellular Dynamics International Thomas Novak hiPSC Derivation Generation and characterization of high-quality, footprint-free human induced pluripotent stem cell lines from 3,000 donors to investigate multigenic diseases $16,000,000
Gladstone Institutes Steven Finkbeiner Early Translational IV Development of Novel Autophagy Inducers to Block the Progression of and Treat Amyotrophic Lateral Sclerosis (ALS) and Other Neurodegenerative Diseases $2,278,080
University of California, Berkeley Lin He New Faculty II The roles of non-coding RNAs in the self-renewal and differentiation of pluripotent stem cells $1,406,823
University of California, Irvine Peter Donovan Research Training II Research Training Program II $6,315,379
Gladstone Institutes Deepak Srivastava Early Translational III Direct Cardiac Reprogramming for Heart Regeneration $6,319,110
University of California, Davis Kyriacos Athanasiou Early Translational III Tissue engineered cartilage from autologous, dermis-isolated, adult, stem (DIAS) cells $1,735,703
California State University, Long Beach Lisa Klig Bridges CIRM Stem Cell Research Biotechnology Training Program $3,513,898
Cedars-Sinai Medical Center Clive Svendsen Disease Team Therapy Development - Research Progenitor Cells Secreting GDNF for the Treatment of ALS $16,961,287
Stanford University Fan Yang Tools and Technologies III Injectable Macroporous Matrices to Enhance Stem Cell Engraftment and Survival $1,452,708
San Jose State University Tzvia Abramson Bridges Stem Cell Internships for Laboratory-based Learning (SCILL) $4,201,707
California State University, Channel Islands Ching-Hua Wang Bridges Curriculum Development and Implementation of Stem Cell Technology and Laboratory Management Emphasis in an Established MS Biotechnology and Bioinformatics Program at (REDACTED) and Co-development of a GE Course on Stem Cel $4,237,241
University of California, Los Angeles Leif Havton Early Translational II Repair of Conus Medullaris/Cauda Equina Injury using Human ES Cell-Derived Motor Neurons $75,628
Stanford University Robert Negrin Transplantation Immunology Regulatory T cell induced tolerance to ESC transplantation $1,382,658
Stanford University Garry Nolan Basic Biology II Kinase signaling analysis of iPS cell reprogramming and differentiation $1,343,100
Salk Institute for Biological Studies Juan Carlos Izpisua Belmonte Early Translational III Direct reprogramming towards vascular progenitors for the treatment of ischemia $2,340,000
University of California, San Diego Shaochen Chen Tools and Technologies III Development of 3D Bioprinting Techniques using Human Embryonic Stem Cells Derived Cardiomyocytes for Cardiac Tissue Engineering $1,368,517
University of California, Los Angeles Carla Koehler Tools and Technologies III A small molecule tool for reducing the malignant potential in reprogramming human iPSCs and ESCs $1,283,900
Stanford University Vittorio Sebastiano Shared Labs Center for Human Embryonic Stem Cell Research and Education $3,434,600
City of Hope Larry Couture Tools and Technologies III Development of a scalable, practical, and transferable GMP-compliant suspension culture-based differentiation process for cardiomyocyte production from human embryonic stem cells. $899,728
Stanford University Irving Weissman Disease Team Research I Development of Therapeutic Antibodies Targeting Human Acute Myeloid Leukemia Stem Cells $18,759,276
University of Southern California Toshio Miki Tools and Technologies III Development of a clinical-grade extracorporeal liver support system using human induced pluripotent stem cell-derived hepatic cells $1,257,372
University of California, San Francisco Daniel Lim Tools and Technologies II Development and preclinical testing of new devices for cell transplantation to the brain. $1,797,426
Stanford University Helen Blau Basic Biology V Mass Cytometry to Delineate the Human Muscle Stem Cell Hierarchy and Dysfunction in Aging $1,175,357
University of California, San Diego Thomas Kipps Disease Team Therapy Development III Therapeutic Eradication of Cancer Stem Cells $4,179,598
ViaCyte, Inc. Howard Foyt Strategic Partnership I Preclinical and clinical testing of a stem cell-based combination product for insulin-dependent diabetes $10,075,070
University of California, San Francisco Andrew Leavitt Tools and Technologies III Small molecule tools and scale-up technologies to expand human umbilical cord blood stem and progenitor cells for clinical and research use $1,416,600
City of Hope Yanhong Shi Early Translational II Developing a therapeutic candidate for Canavan disease using induced pluripotent stem cell $1,835,983
University of Southern California Mark Humayun Disease Team Therapy Development III Phase 1 Safety Assessment of CPCB-RPE1, hESC-derived RPE Cell Coated Parylene Membrane Implants, in Patients with Advanced Dry Age Related Macular Degeneration $17,128,661
University of California, Santa Cruz Lindsay Hinck Shared Labs Shared Stem Cell Facility $1,721,129
San Francisco State University Carmen Domingo Bridges Bridges to Stem Cell Research $4,201,420
Cedars-Sinai Medical Center Paul Noble Basic Biology V Innate Immune Regulation of Lung Alveolar Stem Cell Renewal in Mouse and Man $624,816
University of California, Los Angeles Samantha Butler Basic Biology V Assessing the mechanism by which the Bone Morphogenetic Proteins direct stem cell fate $545,962
University of California, San Diego Douglas Galasko Tissue Collection for Disease Modeling Collection of skin biopsies to prepare fibroblasts from patients with Alzheimer's disease and cognitively healthy elderly controls $643,693
Stanford University Joseph Wu Early Translational III Heart Repair with Human Tissue Engineered Myocardium $4,397,241
Stanford University Judith Shizuru Disease Team Therapy Development - Research A monoclonal antibody that depletes blood stem cells and enables chemotherapy free transplants $19,068,382
University of California, Los Angeles Yi Sun Basic Biology III Studying neurotransmission of normal and diseased human ES cell-derived neurons in vivo $1,382,400
University of California, San Diego Mana Parast New Faculty Physician Scientist Human pluripotent stem cell-based therapeutics for preeclampsia $2,974,750
Sangamo BioSciences, Inc. Fyodor Urnov Strategic Partnership II A Treatment For Beta-thalassemia via High-Efficiency Targeted Genome Editing of Hematopoietic Stem Cells $6,374,150
University of California, San Diego Wei Wang Basic Biology V Systems-level discovery of the regulatory mechanisms directing differentiation of hESC $1,161,000
University of California, Merced Kara McCloskey Basic Biology V Directed Differentiation of Specialized Endothelial Cells $476,052
ViaCyte, Inc. Allan Robins Disease Team Research I Cell Therapy for Diabetes $22,999,933
StemCells, Inc. Alexandra Capela Disease Team Therapy Development - Research Restoration of memory in Alzheimer’s disease: a new paradigm using neural stem cell therapy $8,901,641
University of California, Berkeley David Schaffer Shared Labs Human Embryonic Stem Cell Shared Research Laboratory $1,688,129
University of California, San Francisco Morton Cowan Early Translational III Gene Correction of Autologous Hematopoietic Stem Cells in Artemis Deficient SCID $3,931,662
Buck Institute for Age Research Xianmin Zeng Shared Labs CIRM Shared Research Laboratory for Stem Cells and Aging $3,478,933
San Diego State University Ricardo Zayas New Faculty II The molecular basis underlying adult neurogenesis during regeneration and tissue renewal $1,712,225
University of Southern California Robert Maxson Research Training II CIRM Stem Cell Biology Training Program $6,162,045
University of California, Davis Roslyn Isseroff Early Translational II Bone Marrow Mesenchymal Stem Cells to Heal Chronic Diabetic Wounds $4,635,576
University of California, San Francisco Mark Anderson Basic Biology V Generation of a functional thymus to induce immune tolerance to stem cell derivatives $1,191,000
Salk Institute for Biological Studies Lei Wang New Faculty I Genetic Encoding Novel Amino Acids in Embryonic Stem Cells for Molecular Understanding of Differentiation to Dopamine Neurons $2,587,742
University of Southern California Martin Pera New Cell Lines New Technology ForThe Derivation of Human Pluripotent Stem Cell Lines For Clinical Use $1,266,134
University of California, San Diego Maike Sander Basic Biology IV Deciphering transcriptional control of pancreatic beta-cell maturation in vitro $1,258,560
Sanford-Burnham Medical Research Institute Gregg Duester SEED Grant Retinoic Acid-FGF Antagonism during Motor Neuron Differentiation of Human ES Cells $695,229
California State University, Fullerton Nilay Patel Bridges Stem Cell Training Program - A Bridge to Stem Cell Research $3,050,901
City of Hope John Zaia Disease Team Research I ZIinc Finger Nuclease-Based Stem Cell Therapy for AIDS $14,536,969
University of California, San Diego Lawrence Goldstein Basic Biology V Elucidating pathways from hereditary Alzheimer mutations to pathological tau phenotypes $1,050,300
Stanford University Brian Rutt Tools and Technologies II Development of Single Cell MRI Technology using Genetically-Encoded Iron-Based Reporters $1,833,348
University of California, San Diego Karl Willert Shared Labs Enhancing Facilities for Genetic Manipulation and Engineering of Human Embryonic Stem Cells $1,737,694
Buck Institute for Age Research Deepak Lamba Basic Biology IV 3D Modeling of Retina using Polymer Scaffolds for Understanding Disease Pathogenesis $1,212,553
University of California, San Diego Shyni Varghese New Faculty II A Novel Microenvironment-Mediated Functional Skeletal Muscle from Human Embryonic Stem Cells and their In Vivo Engraftment $2,300,569
University of California, Davis Vicki Wheelock Disease Team Therapy Planning I MSC engineered to produce BDNF for the treatment of Huntington's disease $97,564
University of California, San Francisco Long-cheng Li New Cell Lines Induction of pluripotent stem cells by small RNA-guided transcriptional activation $1,368,461
University of California, San Francisco A. Washington Major Facilities UCSF CIRM Building $34,862,400
University of California, Irvine Lisa Flanagan Tools and Technologies I Novel Separation of Stem Cell Subpopulations $861,122
City of Hope Paul Salvaterra Creativity Awards Creativity Award Program in Stem Cell Biology for California High School Students $271,857
University of California, San Francisco Ophir Klein New Faculty II Laying the groundwork for building a tooth: analysis of dental epithelial stem cells $3,075,251
University of California, San Francisco Susan Fisher Training Grant I-1 Training Grant I $2,868,145
Sanford-Burnham Medical Research Institute Huei-sheng Chen SEED Grant Development of Neuro-Coupled Human Embryonic Stem Cell-Derived Cardiac Pacemaker Cells. $695,680
University of California, Irvine Leslie Thompson Disease Team Planning Huntington's Disease Team $41,953
Escape Therapeutics, Inc Basil Hantash Transplantation Immunology Development of an immune tolerant hESC source for allogeneic cell therapy applications $1,453,040
Stanford University Julie Baker Comprehensive Grant Functional Genomic Analysis of Chemically Defined Human Embryonic Stem Cell $2,518,303
University of California, San Francisco Heike Daldrup-Link SEED Grant Labeling of human embryonic stem cells with iron oxide nanoparticles and fluorescent dyes for a non-invasive cell depiction with MR imaging and optical imaging $240,214
Children's Hospital of Los Angeles Carolyn Lutzko Shared Labs hESC Facility $1,684,648
iPierian, Inc. Irene Griswold-Prenner Basic Biology II Cellular Reprogramming: Dissecting the Molecular Mechanism and Enhancing Efficiency $1,458,000
University of California, San Diego Lawrence Goldstein Early Translational from Disease Team Conversion Stem Cell-Derived Astrocyte Precursor Transplants in Amyotrophic Lateral Sclerosis $3,995,136
University of California, Santa Cruz Bin Chen New Faculty I Molecular mechanisms of neural stem cell differentiation in the developing brain $2,147,592
University of California, Davis Jan Nolta Early Translational I Sustained siRNA production from human MSC to treat Huntingtons Disease and other neurodegenerative disorders $2,615,674
Stanford University Thomas Wandless SEED Grant Reprogramming Differentiated Human Cells to a Pluripotent State $380,005
University of California, San Diego Sylvia Evans Research Training II Interdisciplinary Stem Cell Training Program $7,890,588
Asterias Biotherapeutics Jane Lebkowski Strategic Partnership III Track A A Phase I/IIa Dose Escalation Safety Study of [REDACTED] in Patients with Cervical Sensorimotor Complete Spinal Cord Injury $14,323,318
Sanford-Burnham Medical Research Institute Huei-sheng Chen Basic Biology IV Studying Arrhythmogenic Right Ventricular Dysplasia with patient-specific iPS cells $1,582,606
Sanford-Burnham Medical Research Institute Zhuohua Zhang SEED Grant Modeling Parkinson's Disease Using Human Embryonic Stem Cells $701,060
University of California, Los Angeles Irvin Chen Disease Team Research I HPSC based therapy for HIV disease using RNAi to CCR5. $9,905,604
Palo Alto Institute for Research and Education Thomas Rando Basic Biology V Molecular regulation of stem cell potency $966,510
University of California, Berkeley David Schaffer Tools and Technologies II Engineering Defined and Scaleable Systems for Dopaminergic Neuron Differentiation of hPSCs $1,340,816
University of California, San Francisco Linda Giudice Shared Labs Shared Research and Teaching Laboratory: a Non-Federal Human Embryonic Stem Cell Resource for the Bay Area Community $3,291,268
University of California, San Francisco Jeremy Reiter Basic Biology IV Modeling disease in human embryonic stem cells using new genetic tools $1,387,800
Stanford University Judith Shizuru Disease Team Therapy Planning I A monoclonal antibody that depletes blood stem cells and enables chemotherapy free transplants $90,147
Stanford University Michael Longaker New Cell Lines Derivation and analysis of pluripotent stem cell lines with inherited TGF-b mediated disorders from donated IVF embryos and reprogrammed adult skin fibroblasts $1,406,636
University of Southern California Chrysostomos Nikias Major Facilities Broad CIRM Facility at USC $26,972,500
University of California, San Francisco Ann Zovein New Faculty Physician Scientist Human endothelial reprogramming for hematopoietic stem cell therapy. $2,319,784
ViaCyte, Inc. Evert Kroon Tools and Technologies I Development of the Theracyte Cellular Encapsulation System for Delivery of human ES Cell-derived Pancreatic Islets and Progenitors. $827,072
University of California, San Francisco Emmanuelle Passegue New Faculty II Mechanisms Underlying the Responses of Normal and Cancer Stem Cells to Environmental and Therapeutic Insults $2,124,488
University of California, San Diego Lawrence Goldstein Training Grant I-1 Interdisciplinary Stem Cell Training Program at UCSD $3,459,396
Ludwig Institute for Cancer Research Bing Ren SEED Grant Mapping the transcriptional regulatory elements in the genome of hESC $653,823
Children's Hospital of Los Angeles Donald Kohn Disease Team Planning STEM CELL GENE THERAPY FOR SICKLE CELL DISEASE $12,131

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