All CIRM Grants

Institution Researcher name Grant Type Grant Title Award Value
University of California, Irvine Brian Cummings Therapeutic Translational Research Projects An optimized human neural stem cell line (hNSC) for the treatment of traumatic brain injury (TBI) $4,804,737
University of California, San Diego Mark Tuszynski Therapeutic Translational Research Projects Human Embryonic Stem Cell-Derived Neural Stem Cells for Severe Spinal Cord Injury (SCI) $6,235,897
Sanford Burnham Prebys Medical Discovery Institute Evan Snyder Therapeutic Translational Research Projects Human Neural Stem Cells (hNSCs) for neuroprotection in perinatal hypoxic-ischemic brain injury (HII)-Pre-IND-enabling Studies $4,963,684
City of Hope, Beckman Research Institute Saul Priceman Clinical Trial Stage Projects A Phase I Study of Chimeric Antigen Receptor Engineered Stem/Memory T Cells for the Treatment of HER2-Positive Brain Metastases $9,015,149
University of Southern California Mark Humayun Therapeutic Translational Research Projects PRPE-SF, polarized hESC-derived RPE Soluble Factors, as a Therapy for Early Stage Dry Age-related Macular Degeneration $3,733,556
University of California, Davis Mehrdad Abedi Conference - The 2020 Alpha Stem Cell Clinic Annual Symposium CIRM - Leading the New Era of Living Medicines $60,000
University of California, San Diego Stephanie Cherqui Clinical Trial Stage Projects Phase 1/2 study for autologous human CD34+ hematopoietic stem cells ex vivo transduced with pCCL-CTNS lentiviral vector for treatment of Cystinosis. $11,999,944
University of California, San Francisco Peter Stock Clinical Trial Stage Projects Pancreatic Islets and Parathyroid Gland Co-transplantation for Treatment of Diabetes in the Intra-Muscular Site: PARADIGM $11,083,012
Aspen Neuroscience Jeanne Loring Progression Award - Discovery Stage Research Projects Autologous therapy for Parkinson's disease: single cell RNAseq for in depth characterization of transplanted cells $201,150
University of California, San Francisco Mark Walters Late Stage Preclinical Projects Curing Sickle cell Disease with CRISPR-Cas9 genome editing $2,242,805
University of California, Los Angeles Theodore Nowicki Clinical Trial Stage Projects Genetic Modification of Stem Cells and T cells to Activate the Immune System to Target Solid Tumors $4,693,839
Rocket Pharmaceuticals, Inc. Kinnari Patel Clinical Trial Stage Projects LADICell $6,567,085
Cal State Univ, San Marcos Bianca Mothe Conference - Manage The Bridges Annual Meeting 2020 and 2021 Bridges Annual Meeting $320,000
Ankasa Regenerative Therapeutics Ying Zhu Late Stage Preclinical Projects IND-enabling development of ART352-L, an endogenous stem cell reactivation therapy to enhance bone healing in the elderly $3,994,246
Stanford University Judith Shizuru Clinical Trial Stage Projects A monoclonal antibody that depletes blood stem cells and enables chemotherapy free transplants $3,715,031
University of California, Irvine Leslie Thompson Late Stage Preclinical Projects An hESC-derived hNSC Therapeutic for Huntington’s Disease $5,635,393
Stanford University Everett Meyer Clinical Trial Stage Projects Induction of Tolerance by Combinatorial Therapy w/ Donor Stem Cells and Expanded Recipient Treg cells in HLA-mismatched Kidney Transplant Recipients $11,955,585
Angiocrine Bioscience, Inc. Edward Kavalerchik Clinical Trial Stage Projects AB-205-001 Phase 1b Trial and Related Activities to Support Clinical Development of AB-205 $6,192,579
University of California, Davis Diana Farmer Late Stage Preclinical Projects Placental Mesenchymal Stem Cell Augmentation of Fetal Myelomeningocele Repair $5,666,077
Pathways to Stem Cell Science Victoria Fox Conference - Manage The SPARK Annual Meeting 2019 SPARK Annual Meeting $49,915
University of California, San Diego Jonathan Lin Quest - Discovery Stage Research Projects Small Molecule Proteostasis Regulators to Treat Photoreceptor Diseases $1,160,648
Children's Hospital of Los Angeles Tracy Grikscheit Quest - Discovery Stage Research Projects Universal Pluripotent Liver Failure Therapy (UPLiFT) $1,297,512
Scripps Research Institute Stuart Lipton Quest - Discovery Stage Research Projects Drug Development for Autism Spectrum Disorder Using Human Patient iPSCs $1,827,576
Stanford University Philip Beachy Quest - Discovery Stage Research Projects Pluripotent stem cell-derived bladder epithelial progenitors for definitive cell replacement therapy of bladder cancer $1,265,436
University of Southern California Neil Segil Quest - Discovery Stage Research Projects A screen for drugs to protect against chemotherapy-induced hearing loss, using sensory hair cells derived by direct lineage reprogramming from hiPSCs $741,574
Stanford University Alan Cheng Quest - Discovery Stage Research Projects Modulation of the Wnt pathway to restore inner ear function $1,394,870
City of Hope, Beckman Research Institute Xiuli Wang Late Stage Preclinical Projects CMV-specific T cells expressing anti-HIV CAR and CMV vaccine boost as immunotherapy for HIV/AIDS $3,812,797
University of California, San Francisco Karin Gaensler Therapeutic Translational Research Projects Developing engineered autologous leukemia vaccines to target residual leukemic stem cells $4,171,728
University of California, Los Angeles Steven Schwartz Therapeutic Translational Research Projects Clinical Translation of Autologous Regenerative Cell Therapy for Blindness $5,068,026
Stanford University Theodore Leng Therapeutic Translational Research Projects NeuBright, a purified allogeneic cell therapy product for treatment of Dry Age-related Macular Degeneration $4,235,758
University of California, San Francisco Mark Walters Conference - The 2019 Alpha Stem Cell Clinic Annual Symposium 2019 Alpha Stem Cell Clinic Symposium - Mending Stem Cells: The Past, Present & Future Regenerative Medicine” $60,000
Stanford University Vittorio Sebastiano Quest - Discovery Stage Research Projects Regenerative Thymic Tissues as Curative Cell Therapy for Patients with 22q11 Deletion Syndrome $1,251,720
University of California, San Diego Eric Adler Quest - Discovery Stage Research Projects Genetically Modified Hematopoietic Stem Cells for the Treatment of Danon Disease $1,393,200
University of California, Los Angeles Lili Yang Quest - Discovery Stage Research Projects Preclinical Development of An HSC-Engineered Off-The-Shelf iNKT Cell Therapy for Cancer $1,404,000
Gladstone Institutes, J. David Li Gan Quest - Discovery Stage Research Projects Develop iPSC-derived microglia to treat progranulin-deficient Frontotemporal Dementia $1,547,157
Salk Institute for Biological Studies Ronald Evans Quest - Discovery Stage Research Projects Therapeutic immune tolerant human islet-like organoids (HILOs) for Type 1 Diabetes $1,637,209
Poseida Therapeutics, Inc. Devon Shedlock Late Stage Preclinical Projects Late-Stage Preclinical Study of CAR-T Memory Stem Cells Targeting PSMA (P-PSMA-101) for the Treatment of Castrate-Resistant Metastatic Prostate Cancer $3,992,090
University of California, San Francisco Hideho Okada Quest - Discovery Stage Research Projects Non-viral reprogramming of the endogenous TCRα locus to direct stem memory T cells against shared neoantigens in malignant gliomas $900,000
City of Hope, Beckman Research Institute Saul Priceman Quest - Discovery Stage Research Projects Chimeric Antigen Receptor-Engineered Stem/Memory T Cells for the Treatment of Recurrent Ovarian Cancer $1,381,104
University of California, San Francisco Krystof Bankiewicz Late Stage Preclinical Projects MRI Guided Delivery of Neural Progenitor Cells Secreting GDNF for the Treatment of Parkinson's disease $5,811,340
City of Hope, Beckman Research Institute John Zaia Late Stage Preclinical Projects Ex Vivo Gene Engineering of Blood Stem Cells for Enhanced Chemotherapy Efficacy in Glioblastoma Patients $3,684,259
University of California, Los Angeles Steven Dubinett Clinical Trial Stage Projects A phase I trial of intratumoral administration of CCL21-gene modified dendritic cell (DC) combined with intravenous pembrolizumab for advanced NSCLC $11,815,315
MAX BioPharma, Inc. Farhad Parhami Therapeutic Translational Research Projects Therapeutic development of Oxy200, an oxysterol with bone anabolic and anti-resorptive properties for intervention in osteoporosis $1,689,855
Stanford University Bertha Chen Therapeutic Translational Research Projects Autologous iPSC-derived smooth muscle cell therapy for treatment of urinary incontinence $5,977,155
University of California, Irvine Magdalene Seiler Therapeutic Translational Research Projects Morphological and functional integration of stem cell derived retina organoid sheets into degenerating retina models $4,769,039
Children's Hospital of Oakland Research Institute Henry Erlich Diagnostic Translational Research Projects Development of a Noninvasive Prenatal Test for Beta-Hemoglobinopathies for Earlier Stem Cell Therapeutic Interventions $1,721,606
University of California, San Francisco Morton Cowan Clinical Trial Stage Projects Gene Transfer for Artemis-Deficient Severe Combined Immunodeficiency Using a Lentiviral Vector to Transduce Autologous CD34 Hematopoietic Stem Cells $12,000,000
Stanford University Crystal Mackall Clinical Trial Stage Projects Phase 1 Study of CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells in Adults with Recurrent or Refractory B Cell Malignancies $11,034,982
Sangamo BioSciences, Inc. Weston Miller Clinical Trial Stage Projects A Phase 1/2 Study to Assess the Safety, Tolerability, and Efficacy of ST-400 Autologous HSPC Transplant in Transfusion-dependent β-Thalassemia $8,000,000
City of Hope, Beckman Research Institute Joseph Rosenthal Clinical Trial Stage Projects Treatment of sickle cell disease by induction of mixed chimerism and immune tolerance using CD4+ T-depleted haploidentical blood stem cell transplant $5,742,180
Fate Therapeutics, Inc. Bob Valamehr Late Stage Preclinical Projects IND enabling development of FT516: A Natural Killer Cell Immunotherapy for Cancer Derived from a Human Inducible Pluripotent Stem Cell $4,000,000
Medeor Therapeutics, Inc. Karen Smith Clinical Trial Stage Projects Cellular Immunotherapy for Induction of Immune Tolerance in HLA Matched Living Donor Kidney Transplant Recipients $18,763,585
University of California, Irvine Leslie Thompson Conference II Stem Cells for Huntington’s Disease (HD) International (SC4HDI) Conference $31,727
Keystone Symposia on Molecular and Cellular Biology Thale Jarvis Conference II iPSCs: A Decade of Progress and Beyond $35,000
University of California, San Francisco David Rowitch Conference II “Myelin Through the Ages: Evolution, Development, Degeneration and Disease” - 2018 Gordon Research Conference (GRC) and Gordon Research Seminar (GRS) $10,000
International Society for Stem Cell Research Glori Rosenson Conference II ISSCR 2019 Nucleus Forum $24,000
International Society for Stem Cell Research Cathy Vijeh Conference II ISSCR 2019 $50,000
Stanford University Joseph Wu Conference II 2018 Stanford Drug Discovery and Stem Cell Technology Conference $15,000
University of California, Riverside Xiaoping Hu Conference II 19th Annual UC System-wide Bioengineering Symposium $14,536
University of California, Los Angeles John Adams Conference - The 2018 Alpha Stem Cell Clinic Annual Symposium Delivery of Stem Cell Therapeutics to Patients $60,000
University of California, Irvine Aileen Anderson Quest - Discovery Stage Research Projects Generation and in vitro profiling of neural stem cell lines to predict in vivo efficacy for chronic cervical spinal cord injury. $1,575,613
City of Hope, Beckman Research Institute Saswati Chatterjee Quest - Discovery Stage Research Projects Genome Editing of Sinusoidal Endothelial Stem Cells for Permanent Correction of Hemophilia A $2,182,193
Neurona Therapeutics Cory Nicholas Quest - Discovery Stage Research Projects Development of a Cellular Therapeutic for Treatment of Epilepsy $1,616,536
University of California, San Diego Yang Xu Quest - Discovery Stage Research Projects Development of immune invisible beta cells as a cell therapy for type 1 diabetes through genetic modification of hESCs $1,960,560
ViaCyte, Inc. Alan Agulnick Quest - Discovery Stage Research Projects Preclinical development of an immune evasive islet cell replacement therapy for type 1 diabetes $1,470,987
Stanford University Helen Blau Quest - Discovery Stage Research Projects Stimulating endogenous muscle stem cells to counter muscle atrophy $2,198,687
University of California, San Diego Mark Tuszynski Quest - Discovery Stage Research Projects Neural Stem Cell Relays for Severe Spinal Cord Injury $1,905,173
Stanford University Kyle Loh Quest - Discovery Stage Research Projects Towards hepatocyte cell replacement therapy: developing a renewable source of human hepatocytes from pluripotent stem cells $1,968,456
University of California, Los Angeles April Pyle Quest - Discovery Stage Research Projects Identification and Generation of Long Term Repopulating Human Muscle Stem Cells from Human Pluripotent Stem Cells $2,184,000
University of California, Los Angeles Stanley Carmichael Quest - Discovery Stage Research Projects iPS Glial Therapy for White Matter Stroke and Vascular Dementia $2,096,095
University of California, San Diego Tannishtha Reya Quest - Discovery Stage Research Projects Targeting Cancer Stem Cells in Hematologic Malignancies $1,960,560
University of California, Los Angeles Scott Kitchen Quest - Discovery Stage Research Projects Engineering Lifelong Cellular Immunity to HIV $1,701,178
University of California, San Francisco Shuvo Roy Quest - Discovery Stage Research Projects Silicon Nanopore Membrane encapsulated enriched-Beta Clusters for Type 1 Diabetes treatment $1,113,000
Cedars-Sinai Medical Center Dmitriy Sheyn Inception - Discovery Stage Research Projects IVD rejuvenation using iPSC-derived notochordal cells $241,992
Zenobia Therapeutics Vicki Nienaber Inception - Discovery Stage Research Projects A new phenotypic screening platform that identifies biologically-relevant targets and lead compounds for the treatment of Parkinson’s disease $112,500
University of California, Los Angeles Alireza Moshaverinia Inception - Discovery Stage Research Projects Gingival mesenchymal stem cells as a novel treatment modality for periodontal tissue regeneration $194,483
University of California, San Diego Karl Wahlin Inception - Discovery Stage Research Projects An IPSC cell based model of macular degeneration for drug discovery. $232,200
Stanford University Anthony Oro Therapeutic Translational Research Projects DEBCT: Genetically Corrected, Induced Pluripotent Cell-Derived Epithelial Sheets for Definitive Treatment of Dystrophic Epidermolysis Bullosa $5,107,353
University of California, San Diego Catriona Jamieson Therapeutic Translational Research Projects A Splicing Modulator Targeting Cancer Stem Cells in Acute Myeloid Leukemia $2,511,767
University of California, San Diego Dan Kaufman Therapeutic Translational Research Projects Human Embryonic Stem Cell-Derived Natural Killer Cells for Cancer Treatment $4,698,821
University of California, San Francisco Semil Choksi Inception - Discovery Stage Research Projects Generation of human airway stem cells by direct transcriptional reprogramming for disease modeling and regeneration $238,408
Stanford University Guillem Pratx Inception - Discovery Stage Research Projects Novel metabolic labeling method for tracking stem cells to irradiated salivary glands using PET $229,350
University of California, Davis Alyssa Panitch Inception - Discovery Stage Research Projects Development of treatments to improve healing of ischemic wounds $235,099
University of California, San Diego Gerald Morris Inception - Discovery Stage Research Projects Identification of antigenic neo-epitopes from in vitro reprogrammed human tissue precursors for regenerative therapy $193,500
Stanford University Hiromitsu Nakauchi Inception - Discovery Stage Research Projects Optimizing self-renewal signaling kinetics to stabilize ex vivo hematopoietic stem cell expansion $210,906
Human BioMolecular Research Institute John Cashman Inception - Discovery Stage Research Projects Human Pancreatic Cancer Stem Cells: Developing a Novel Drug for Cancer Eradication $303,785
Loma Linda University Julia Unternaehrer-Hamm Inception - Discovery Stage Research Projects Targeting cancer stem cells with nanoparticle RNAi delivery to prevent recurrence and metastasis of ovarian cancer $172,870
University of California, Davis Alice Tarantal Inception - Discovery Stage Research Projects Enhanced Branching Morphogenesis and Pluripotent Cell Lineage Differentiation for Pediatric Regenerative Therapies $235,800
Palo Alto Veterans Institute for Research Ngan Huang Inception - Discovery Stage Research Projects iPSC-Derived Smooth Muscle Progenitors for Treatment of Abdominal Aortic Aneurysm $172,621
Loma Linda University David Baylink Inception - Discovery Stage Research Projects Bone Marrow Targeting of Hematopoietic Stem Cells Engineered to Overexpress 25-OH-VD3 1-α-hydroxylase for Acute Myeloid Leukemia Therapy $178,967
Poseida Therapeutics, Inc. Matthew Spear Clinical Trial Stage Projects Clinical Study of T stem cell memory (Tscm)-based CAR-T cells in Patients with Multiple Myeloma $19,813,407
University of California, Davis Gerhard Bauer Conference - Manage The SPARK Annual Meeting The 2018 SPARK Annual Meeting $39,559
Cal State Univ, San Marcos Bianca Mothe Conference - Manage The Bridges Annual Meeting 2018 and 2019 Bridges Annual Meeting $305,622
Calibr Kristen Johnson Clinical Trial Stage Projects Evaluation of the Safety and Tolerability of KA34 in a Phase 1, Double-Blind, Dose Escalation Trial in Patients with Knee Osteoarthritis $8,447,523
Children's Hospital of Los Angeles Michael Pulsipher Clinical Trial Stage Projects Antiviral Cellular Therapy for Enhancing T-cell Reconstitution Before or After Hematopoietic Stem Cell Transplantation (ACES) $4,825,587
RUNX1 Research Program Timothy Babich Conference II Living with and Curing RUNX1 FPD/AML Forum $9,500
Alliance Forum Foundation George Hara Conference II 2017 World Alliance Forum in San Francisco (WAFSF) "Healthcare Game Changers" $5,000
Stanford University Matthew Porteus Late Stage Preclinical Projects Genome Editing of Autologous Hematopoietic Stem Cells to Treat Sickle Cell Disease $4,849,363
Nohla Therapeutics Inc Colleen Delaney Clinical Trial Stage Projects A Phase 2 Open-Label, Multi-Center, Randomized, Controlled, Optimal Dose-Finding Study of DCC-UCB in Adults Receiving High Dose Chemotherapy for AML $4,310,000
ViaCyte, Inc. Howard Foyt Clinical Trial Stage Projects Clinical trial of directly vascularized islet cell replacement therapy for high-risk type 1 diabetes $19,752,463

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