All CIRM Grants

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Institution Researcher name Grant Type Grant Title Award Value
University of Southern California Dr. Neil Segil Quest – Discovery Stage Research Projects A screen for drugs to protect against chemotherapy-induced hearing loss, using sensory hair cells derived by direct lineage reprogramming from hiPSCs $741,574
Salk Institute for Biological Studies Ronald Mark Evans Quest – Discovery Stage Research Projects Therapeutic immune tolerant human islet-like organoids (HILOs) for Type 1 Diabetes $1,637,209
Gladstone Institutes, J. David Li Gan Quest – Discovery Stage Research Projects Develop iPSC-derived microglia to treat progranulin-deficient Frontotemporal Dementia $1,547,157
University of California, Los Angeles Dr. Lili Yang Quest – Discovery Stage Research Projects Preclinical Development of An HSC-Engineered Off-The-Shelf iNKT Cell Therapy for Cancer $1,404,000
University of California, San Diego Dr. Eric D. Adler MD Quest – Discovery Stage Research Projects Genetically Modified Hematopoietic Stem Cells for the Treatment of Danon Disease $1,393,200
Stanford University Dr. Katja Weinacht Quest – Discovery Stage Research Projects Regenerative Thymic Tissues as Curative Cell Therapy for Patients with 22q11 Deletion Syndrome $1,251,720
City of Hope, Beckman Research Institute Dr Saul J Priceman Quest – Discovery Stage Research Projects Chimeric Antigen Receptor-Engineered Stem/Memory T Cells for the Treatment of Recurrent Ovarian Cancer $1,351,174
Stanford University Dr. Philip Arden Beachy PhD Quest – Discovery Stage Research Projects Pluripotent stem cell-derived bladder epithelial progenitors for definitive cell replacement therapy of bladder cancer $1,265,436
Scripps Research Institute Stuart A Lipton Quest – Discovery Stage Research Projects Drug Development for Autism Spectrum Disorder Using Human Patient iPSCs $1,827,576
University of California, San Francisco Dr. Hideho Okada Quest – Discovery Stage Research Projects Non-viral reprogramming of the endogenous TCRα locus to direct stem memory T cells against shared neoantigens in malignant gliomas $900,000
Children’s Hospital of Los Angeles Dr. Mark R Frey Quest – Discovery Stage Research Projects Universal Pluripotent Liver Failure Therapy (UPLiFT) $1,297,512
University of California, San Diego Dr. Jonathan H Lin Quest – Discovery Stage Research Projects Small Molecule Proteostasis Regulators to Treat Photoreceptor Diseases $1,153,937
University of California, Irvine Dr. Aileen J Anderson Quest – Discovery Stage Research Projects Generation and in vitro profiling of neural stem cell lines to predict in vivo efficacy for chronic cervical spinal cord injury. $1,575,613
University of California, San Francisco Dr. Shuvo Roy Quest – Discovery Stage Research Projects Silicon Nanopore Membrane encapsulated enriched-Beta Clusters for Type 1 Diabetes treatment $1,113,000
University of California, Los Angeles Dr. Scott G Kitchen Quest – Discovery Stage Research Projects Engineering Lifelong Cellular Immunity to HIV $1,701,178
University of California, San Diego Dr. Tannishtha Reya Quest – Discovery Stage Research Projects Targeting Cancer Stem Cells in Hematologic Malignancies $1,960,560
University of California, Los Angeles Dr. Thomas Carmichael M.D., Ph.D. Quest – Discovery Stage Research Projects iPS Glial Therapy for White Matter Stroke and Vascular Dementia $2,086,130
University of California, Los Angeles Dr. April Pyle Ph.D. Quest – Discovery Stage Research Projects Identification and Generation of Long Term Repopulating Human Muscle Stem Cells from Human Pluripotent Stem Cells $2,148,519
Stanford University Dr. Kyle M Loh Quest – Discovery Stage Research Projects Towards hepatocyte cell replacement therapy: developing a renewable source of human hepatocytes from pluripotent stem cells $1,968,456
University of California, San Diego Mark H Tuszynski Quest – Discovery Stage Research Projects Neural Stem Cell Relays for Severe Spinal Cord Injury $1,638,900
Stanford University Dr. Helen M Blau Quest – Discovery Stage Research Projects Stimulating endogenous muscle stem cells to counter muscle atrophy $2,198,687
ViaCyte, Inc. Dr. Alan D. Agulnick Quest – Discovery Stage Research Projects Preclinical development of an immune evasive islet cell replacement therapy for type 1 diabetes $1,470,987
University of California, San Diego Dr Yang Xu Quest – Discovery Stage Research Projects Development of immune invisible beta cells as a cell therapy for type 1 diabetes through genetic modification of hESCs $1,924,791
Neurona Therapeutics Dr. Cory R Nicholas Quest – Discovery Stage Research Projects Development of a Cellular Therapeutic for Treatment of Epilepsy $1,616,536
City of Hope, Beckman Research Institute Dr. Saswati Chatterjee Quest – Discovery Stage Research Projects Genome Editing of Sinusoidal Endothelial Stem Cells for Permanent Correction of Hemophilia A $2,182,193
University of California, Irvine Dr. Brian J. Cummings Quest – Discovery Stage Research Projects Identification and characterization of the optimal human neural stem cell line (hNSC) for the treatment of traumatic brain injury (TBI) 2.0. $1,671,213
University of California, Los Angeles Dr. Vaithilingaraja Arumugaswami PhD Quest – Discovery Stage Research Projects Immunization strategies to prevent Zika viral congenital eye and brain disease $2,128,867
Rumi Scientific CA Ali H. Brivanlou Quest – Discovery Stage Research Projects Discovery of therapeutics for Huntington’s Disease $1,399,800
University of California, Los Angeles UCLA Gay M Crooks Quest – Discovery Stage Research Projects Platform Technology for Pluripotent Stem Cell-Derived T cell Immunotherapy $965,636
X-Therma Inc. Dr. Xiaoxi Wei Quest – Discovery Stage Research Projects Non-Toxic, Highly-Effective Bioinspired Cryoprotectants for On-Demand Stem Cell Therapies $887,883
University of California, Los Angeles Dr. Caroline Y. Kuo Quest – Discovery Stage Research Projects Targeted Gene Editing in the Treatment of X-Linked Hyper-IgM Syndrome $1,512,333
University of California, Davis Dr. Deborah K Lieu Quest – Discovery Stage Research Projects Microenvironment for hiPSC-derived pacemaking cardiomyocytes $2,042,438
Stanford University Dr. Mark Mercola Quest – Discovery Stage Research Projects Multipotent Cardiovascular Progenitor Regeneration of the Myocardium after MI $1,809,234
University of California, San Diego Professor Yuan Chen Quest – Discovery Stage Research Projects A Novel Approach to Eradicate Cancer Stem Cells $279,977
City of Hope, Beckman Research Institute Professor Yuan Chen Quest – Discovery Stage Research Projects A Novel Approach to Eradicate Cancer Stem Cells $1,539,935
University of California, Berkeley 5106433559 Kevin E. Healy Quest – Discovery Stage Research Projects Human Cardiac Chip for Assessment of Proarrhythmic Risk $899,581
University of California, San Francisco Dr. Holger F Willenbring Quest – Discovery Stage Research Projects Preclinical development of AAV vector-mediated in vivo hepatic reprogramming of myofibroblasts as a therapy for liver fibrosis $1,638,389
Scaled Biolabs Inc. Dr Justin Cooper-White Quest – Discovery Stage Research Projects A tool for rapid development of clinical-grade protocols for dopaminergic neuronal differentiation of Parkinson’s Disease patient-derived iPSCs $657,528
City of Hope, Beckman Research Institute Markus Müschen Quest – Discovery Stage Research Projects Lgr5-mediated self-renewal in B cell selection and leukemia-initiation $2,183,223
University of California, San Diego Professor Alysson R Muotri Quest – Discovery Stage Research Projects A treatment for Zika virus infection and neuroprotection efficacy $1,924,524
Stanford University Dr. Matthew H Porteus Quest – Discovery Stage Research Projects Genome Editing to Correct Cystic Fibrosis Mutations in Airway Stem Cells $1,968,456
University of California, San Francisco Dr. Julie B Sneddon Quest – Discovery Stage Research Projects Designing a cellular niche for transplantation of human embryonic stem cell-derived beta cells $2,006,076
University of California, Los Angeles Dr. John P Chute Quest – Discovery Stage Research Projects Protein tyrosine phosphatase – sigma inhibitors for hematopoietic regeneration $2,115,735
University of California, San Diego Dan S Kaufman Quest – Discovery Stage Research Projects Targeted off-the-shelf immunotherapy to treat refractory cancers $1,936,936
Parkinson’s Institute Dr. Birgitt Schuele Quest – Discovery Stage Research Projects CRISPR/dCas9 mutant targeting SNCA promoter for downregulation of alpha-synuclein expression as a novel therapeutic approach for Parkinson’s disease $1,288,415
Gladstone Institutes, J. David Dr. Deepak Srivastava Quest – Discovery Stage Research Projects Direct Cardiac Reprogramming for Regenerative Medicine $2,392,157
University of California, Irvine Leslie M Thompson Quest – Discovery Stage Research Projects hNSC-mediated delivery of ApiCCT1 as a candidate therapeutic for Huntington’s disease $1,650,263
Stanford University Dr. Roel Nusse Quest – Discovery Stage Research Projects Preclinical development of human hepatocyte progenitor cells for cell therapy $1,651,211
University of California, San Francisco Dr. Tejal Ashwin Desai Quest – Discovery Stage Research Projects Thin Film Encapsulation Devices for Human Stem Cell derived Insulin Producing Cells $1,092,063
Stanford University Dr. Rosa Bacchetta Quest – Discovery Stage Research Projects GENE EDITING FOR FOXP3 IN HUMAN HSC $984,228
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