Active Awards Portfolio Dashboard

It takes a lot of effort to develop a promising stem cell research idea into an effective treatment that can help patients. CIRM funds a pipeline of projects spanning discovery, translation and clinical stage research. Check out our portfolio of active research awards in our interactive dashboard below. For a detailed list of CIRM-funded clinical trials, visit our Clinical Trials Dashboard.

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Disease

Therapeutic or Technology

Disease	Cell Type	Therapeutic or Technology	Institution	Project Objective
Leukemia, Acute Myeloid (AML)	Embryonic Stem Cell	Donor cell therapy	UCSD	Pre-IND/IDE or Equivalent
Age-related macular degeneration	Adult Stem Cell	Donor cell therapy	Stanford	Pre-IND/IDE or Equivalent
B cell cancers, Leukemia, Leukemia, Acute Myeloid (AML)	Adult Stem Cell	Donor cell therapy	Stanford	Clinical Trial, Phase 1 or Phase 1/2
Kidney Failure	Adult Stem Cell	Donor cell therapy	Medeor Therapeutics	Clinical Trial, Phase 3
Spinal Cord Injury	iPS Cell	Donor cell therapy	Stanford	Development Candidate, Proof of Concept
Huntington's Disease	Embryonic Stem Cell	Donor cell therapy	UC Irvine	IND
Stroke	Embryonic Stem Cell	Donor cell therapy	Stanford	Clinical Trial, Phase 1 or Phase 1/2
Pulmonary Hypertension, Vascular Disease	Adult Stem Cell	Donor cell therapy	Cedars-Sinai	Clinical Trial, Phase 1 or Phase 1/2
Cartilage defect	Embryonic Stem Cell	Donor cell therapy	USC	IND
Sickle Cell Disease	Adult Stem Cell	Donor cell therapy	COH	Clinical Trial, Phase 1 or Phase 1/2
Kidney Failure	Adult Stem Cell	Donor cell therapy	Stanford	Clinical Trial, Phase 1 or Phase 1/2
Spina Bifida	Adult Stem Cell	Donor cell therapy	UC Davis	Clinical Trial, Phase 1 or Phase 1/2
Retinitis Pigmentosa	Other	Donor cell therapy	jCyte	Clinical Trial, Phase 2
Heart failure	Embryonic Stem Cell	Donor cell therapy	Stanford	Clinical Trial, Phase 1 or Phase 1/2
Kidney Failure	Adult Stem Cell	Donor cell therapy	Stanford	Clinical Trial, Phase 1 or Phase 1/2
Heart Disease	iPS Cell	Donor cell therapy	UC Davis	Development Candidate, Proof of Concept
Stroke	iPS Cell	Donor cell therapy	UCLA	Pre-IND/IDE or Equivalent
Inflammatory bowel disease	Adult Stem Cell	Donor cell therapy	Vitabolus, Inc.	Development Candidate, Proof of Concept
Type 1 diabetes	Adult Stem Cell	Donor cell therapy	UCSF	Clinical Trial, Phase 1 or Phase 1/2
Traumatic Brain Injury	iPS Cell	Donor cell therapy	UC Irvine	Development Candidate, Research Insights
Alpha Thalassemia Major	Adult Stem Cell	Donor cell therapy	UCSF	Clinical Trial, Phase 1 or Phase 1/2
Retinitis Pigmentosa	Embryonic Stem Cell	Donor cell therapy	UC Irvine	Pre-IND/IDE or Equivalent
COVID-19	Adult Stem Cell	Donor cell therapy	UCSF	Clinical Trial, Phase 2
Cartilage defect, Osteoarthritis	Embryonic Stem Cell	Donor cell therapy	Scripps Health	Development Candidate, Proof of Concept
Epilepsy	Embryonic Stem Cell	Donor cell therapy	Neurona Therapeutics	Clinical Trial, Phase 1 or Phase 1/2
Type 1 diabetes	Embryonic Stem Cell	Donor cell therapy	ViaCyte	Clinical Trial, Phase 1 or Phase 1/2
Traumatic Brain Injury	Embryonic Stem Cell	Donor cell therapy	UC Irvine	Pre-IND/IDE or Equivalent
COVID-19, Respiratory Disorders	Adult Stem Cell	Donor cell therapy	Celularity Inc	Clinical Trial, Phase 1 or Phase 1/2
Spinal Cord Injury	Embryonic Stem Cell	Donor cell therapy	UCSD	Pre-IND/IDE or Equivalent
Liver Disease	iPS Cell	Diagnostic Test	UCSF	Development Candidate, Proof of Concept
Beta Thalassemia, Sickle Cell Disease	Adult Stem Cell	Diagnostic Test	UCSF	Regulated Lab Test, Ready for Validation
Kidney Failure	Adult Stem Cell	Device	UC Davis	Pre-IND/IDE or Equivalent
COVID-19, Respiratory Disorders	Other, Vital Research Opportunity	Convalescent Plasma	COH	Research Insights
	Embryonic Stem Cell	Cell processing & handling	Stanford	Research Insights
Vascular Disease	Adult Stem Cell	Biologic	UCSD	Pre-IND/IDE or Equivalent
Cartilage defect	Adult Stem Cell	Biologic	The Stone Research Foundation for Sports Medicine and Arthritis	Development Candidate, Proof of Concept
Type 1 diabetes	iPS Cell	Biologic	UCLA	Development Candidate, Proof of Concept
Age-related macular degeneration	Embryonic Stem Cell	Biologic	USC	Pre-IND/IDE or Equivalent
Leukemia, Acute Myeloid (AML)	Cancer Stem Cell	Antibody	Immune-Onc Therapeutics	Clinical Trial, Phase 1 or Phase 1/2
Severe Combined Immunodeficiency, X-linked (X-SCID)	Adult Stem Cell	Antibody	Jasper Therapeutics, Inc.	Clinical Trial, Phase 1 or Phase 1/2
Heart Disease	Adult Stem Cell	Antibody	UCLA	Pre-IND/IDE or Equivalent
B cell cancers, Leukemia	Cancer Stem Cell	Antibody	UCSD	Clinical Trial, Phase 1 or Phase 1/2
			UCLA
			UCSD
			UCLA
			UC Davis
			Scripps
			Cedars-Sinai
			UCSD
			UCLA

California's Stem Cell Agency

California Institute for Regenerative Medicine

Active Awards Portfolio Dashboard

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aa Multiple Diseases (Centers & Resoures)
Aging
Arthritis
Blood Disorders
– Alpha Thalassemia Major
– Anemia
– Beta Thalassemia
– Bone Marrow Transplant and Viral Infection
– Hemophilia A
– Hyper IgM Syndrome
– IPEX Syndrome
– Leukocyte Adhesion Deficiency
– Severe Combined Immunodeficiency, Adenosine deaminase-deficient (ADA-SCID)
– Severe Combined Immunodeficiency, Artemis deficient (ART-SCID)
– Severe Combined Immunodeficiency, X-linked (X-SCID)
– Sickle Cell Disease
– X-linked Chronic Granulomatous Disease
Bone or Cartilage Disease
– Cartilage defect
– Intervertebral disc degeneration
– Osteoarthritis
– Osteonecrosis
– Osteoporosis, malignant infantile
Cancer
– Blood Cancer
–– Acute Myeloid Leukemia
–– B cell cancers
–– HIV-related Lymphoma
–– Leukemia
–– Leukemia, Acute Myeloid (AML)
–– Multiple Myeloma
– Solid Tumors
–– Brain Cancer
–– Breast Cancer
–– Colon Cancer
–– Lung Cancer
–– Melanoma
–– Ovarian Cancer
–– Pancreatic Cancer
–– Prostate Cancer
–– Sarcoma
–– Skin cancer
Developmental Disorders
Fertility
Genetic Disorder
Hearing Loss
Heart Disease
– Heart disease associated with Duchenne muscular dystrophy
– Heart failure
– Pulmonary Hypertension
–– Hypertension, pulmonary arterial
Immune Disease
– Thymic Disorder, 22q11 Deletion/DiGeorge
Incontinence
Infectious Disease
– COVID-19
– HIV/AIDS
– Zika virus
Kidney Disease
– Kidney Failure
Metabolic Disorders
– Cystinosis
– Danon Disease
– Diabetes
–– Diabetic Wounds
–– Type 1 diabetes
– Intestinal Disease
–– Inflammatory bowel disease
– Liver Disease
– Sanfilippo Syndrome/MPS III
Multiple Indications (Alpha Clinics)
Neurological Disorders
– Alzheimer's Disease
– Amyotrophic Lateral Sclerosis
– Angelman Syndrome
– Autism
– Brain Injury, hypoxic, ischemic
– Canavan Disease
– Dementia
– Epilepsy
– Huntington's Disease
– Multiple Sclerosis
– Neuropathy
– Parkinson's Disease
– Rett's Syndrome
– Spina Bifida
– Spinal Cord Injury
– Spinal Muscular Atrophy
– Stroke
– Traumatic Brain Injury
Other
Pediatrics
Respiratory Disorders
– Cystic Fibrosis
– Lung Disease, Fibrosis
Skeletal/Smooth Muscle disorders
– Bladder or Urinary Tract Disorder
– Duchenne Muscular Dystrophy
– Muscle Injury
– Muscular Dystrophy
Skin Disease
– Epidermolysis Bullosa
– Wounds, ulcers
Toxicity
Trauma
Vascular Disease
Vision Loss
– Age-related macular degeneration
– Corneal Damage
– Retinitis Pigmentosa

Therapeutic Approach
– Biologic
–– Antibody
–– Convalescent Plasma
–– Exosomes based therapy
–– Gene modification
–– Nucleic acid based therapy
–– Protein/peptide therapy
–– Vaccine
– Gene Therapy (All)
–– Gene Therapy, cell free
–– Gene-modified, donor cell therapy
–– Gene-modified, personalized cell therapy
– Small molecule therapy
– Device
– Donor cell therapy
– Personalized cell therapy
– Other Components
Technology
– Assay development
– Cell Line Generation-Resource
– Diagnostic Test
– Gene editing tools
– Cell delivery or targeting
– Cell imaging & tracking
– Cell processing & handling
– Exploring disease mechanisms
– Exploring stem cell mechanisms
– Immune tolerance/management
– Model system development
– Specific Cell Type Derivation
– Therapeutic target discovery
– Tissue engineering