Active Awards Portfolio Dashboard

It takes a lot of effort to develop a promising stem cell research idea into an effective treatment that can help patients. CIRM funds a pipeline of projects spanning discovery, translation and clinical stage research. Check out our portfolio of active research awards in our interactive dashboard below. For a detailed list of CIRM-funded clinical trials, visit our Clinical Trials Dashboard.

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Disease Cell Type Therapeutic or Technology Institutionsort ascending Stage Project Objective Details
Traumatic Brain Injury Embryonic Stem Cell Donor cell therapy UC Irvine
Pre-IND/IDE or Equivalent
Traumatic Brain Injury Embryonic Stem Cell Donor cell therapy UC Irvine
Development Candidate
Spinal Cord Injury Adult Stem Cell Donor cell therapy UC Irvine
Development Candidate
Huntington's Disease Embryonic Stem Cell Donor cell therapy UC Irvine
IND
Heart Disease iPS Cell Personalized cell therapy UC Davis
Proof of Concept
HIV-related Lymphoma,
HIV/AIDS
Adult Stem Cell Gene-modified, personalized cell therapy UC Davis
Clinical Trial, Phase 1 or Phase 1/2
Spina Bifida Adult Stem Cell Donor cell therapy UC Davis
IND
Osteonecrosis Adult Stem Cell Small molecule therapy UC Davis
Clinical Trial, Phase 1 or Phase 1/2
Other Embryonic Stem Cell Cell imaging & tracking UC Berkeley
Tool/Resources/Bottleneck
Heart Disease iPS Cell Model system development UC Berkeley
Proof of Concept
Skeletal/Smooth Muscle disorders Adult Stem Cell Small molecule therapy Stanford
Development Candidate
Liver Disease Adult Stem Cell Donor cell therapy Stanford
Development Candidate
Liver Disease Embryonic Stem Cell Donor cell therapy Stanford
Development Candidate, Proof of Concept
Bladder or Urinary Tract Disorder,
Incontinence
iPS Cell Personalized cell therapy Stanford
Pre-IND/IDE or Equivalent
Bladder or Urinary Tract Disorder,
Solid Tumors
Embryonic Stem Cell Donor cell therapy Stanford
Development Candidate, Proof of Concept
Cystic Fibrosis Adult Stem Cell Gene-modified, personalized cell therapy Stanford
Development Candidate
Hearing Loss Adult Stem Cell Protein/peptide therapy Stanford
Development Candidate, Proof of Concept
Kidney Failure Adult Stem Cell Donor cell therapy Stanford
Clinical Trial, Phase 1 or Phase 1/2
Stroke Embryonic Stem Cell Donor cell therapy Stanford
IND
Epidermolysis Bullosa iPS Cell Gene-modified, personalized cell therapy Stanford
Pre-IND/IDE or Equivalent
Age-related macular degeneration Adult Stem Cell Donor cell therapy Stanford
Pre-IND/IDE or Equivalent
IPEX Syndrome,
Immune Disease
Gene Therapy, cell free Stanford
IND
Thymic Disorder, 22q11 Deletion/DiGeorge Embryonic Stem Cell,
iPS Cell
Donor cell therapy Stanford
Development Candidate, Proof of Concept
Immune Disease,
Severe Combined Immunodeficiency, X-linked (X-SCID)
Adult Stem Cell Antibody Stanford
Clinical Trial, Phase 1 or Phase 1/2
Skeletal/Smooth Muscle disorders Adult Stem Cell Protein/peptide therapy Stanford
Research Insights
Kidney Failure Adult Stem Cell Donor cell therapy Stanford
Clinical Trial, Phase 1 or Phase 1/2
B cell cancers,
Leukemia
Adult Stem Cell Gene-modified, personalized cell therapy Stanford
Clinical Trial, Phase 1 or Phase 1/2
Heart Disease Embryonic Stem Cell Donor cell therapy Stanford
IND
Severe Combined Immunodeficiency, X-linked (X-SCID) Adult Stem Cell Antibody Stanford
Clinical Trial, Phase 1 or Phase 1/2
Sickle Cell Disease Adult Stem Cell Gene-modified, personalized cell therapy Stanford
IND
Blood Disorders iPS Cell Model system development Stanford
Research Insights, Tool/Resources/Bottleneck
Heart Disease iPS Cell Donor cell therapy Stanford
Development Candidate, Proof of Concept
Immune Disease,
Severe Combined Immunodeficiency, X-linked (X-SCID)
Adult Stem Cell Gene-modified, personalized cell therapy St. Jude
Clinical Trial, Phase 1 or Phase 1/2
Autism iPS Cell Small molecule therapy Scripps
Development Candidate, Proof of Concept
Beta Thalassemia Adult Stem Cell Gene-modified, personalized cell therapy Sangamo
Clinical Trial, Phase 1 or Phase 1/2
Brain Injury, hypoxic, ischemic Adult Stem Cell Donor cell therapy Sanford-Burnham
Pre-IND/IDE or Equivalent
Stroke Adult Stem Cell Gene-modified, donor cell therapy SanBio, Inc.
Clinical Trial, Phase 2
Type 1 diabetes Embryonic Stem Cell Gene-modified, donor cell therapy Salk
Development Candidate, Proof of Concept
Leukocyte Adhesion Deficiency Adult Stem Cell Gene-modified, personalized cell therapy Rocket Pharmaceuticals, Inc.
Clinical Trial, Phase 1 or Phase 1/2
Multiple Myeloma Adult Stem Cell Gene-modified, personalized cell therapy Poseida Therapeutics
Clinical Trial, Phase 1 or Phase 1/2
Prostate Cancer Adult Stem Cell Gene-modified, personalized cell therapy Poseida Therapeutics
IND
Immune Disease,
Severe Combined Immunodeficiency, Adenosine deaminase-deficient (ADA-SCID)
Adult Stem Cell Gene-modified, personalized cell therapy Orchard Therapeutics
Clinical Trial, Phase 2
Epilepsy Embryonic Stem Cell Donor cell therapy Neurona Therapeutics
Pre-IND/IDE or Equivalent
Kidney Failure Adult Stem Cell Donor cell therapy Medeor Therapeutics
Clinical Trial, Phase 3
Bone or Cartilage Disease Adult Stem Cell Small molecule therapy MAX BioPharma
Pre-IND/IDE or Equivalent
Ovarian Cancer Cancer Stem Cell Nucleic acid based therapy Loma Linda University
Proof of Concept
Spinal Cord Injury Embryonic Stem Cell Donor cell therapy Lineage Cell
Clinical Trial, Phase 1 or Phase 1/2
Retinitis Pigmentosa Adult Stem Cell Donor cell therapy jCyte
Clinical Trial, Phase 2
Retinitis Pigmentosa Donor cell therapy jCyte
Clinical Trial, Phase 2
Kidney Failure Adult Stem Cell Biologic Humacyte
Clinical Trial, Phase 3

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