Active Awards Portfolio Dashboard

It takes a lot of effort to develop a promising stem cell research idea into an effective treatment that can help patients. CIRM funds a pipeline of projects spanning discovery, translation and clinical stage research. Check out our portfolio of active research awards in our interactive dashboard below. For a detailed list of CIRM-funded clinical trials, visit our Clinical Trials Dashboard.

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Disease Cell Typesort descending Therapeutic or Technology Institution Stage Project Objective Details
Kidney Failure Adult Stem Cell Donor cell therapy Stanford
Clinical Trial, Phase 1 or Phase 1/2
Ovarian Cancer Adult Stem Cell Gene-modified, donor cell therapy COH
Pre-IND/IDE or Equivalent
Amyotrophic Lateral Sclerosis Adult Stem Cell Personalized cell therapy BrainStorm
Clinical Trial, Phase 3
Beta Thalassemia Adult Stem Cell Gene-modified, personalized cell therapy Sangamo
Clinical Trial, Phase 1 or Phase 1/2
HIV/AIDS Adult Stem Cell Gene-modified, personalized cell therapy COH
Clinical Trial, Phase 1 or Phase 1/2
Sickle Cell Disease Adult Stem Cell Gene-modified, personalized cell therapy UCSF
IND
Vascular Disease Adult Stem Cell Biologic UCSD
Pre-IND/IDE or Equivalent
Multiple Myeloma Adult Stem Cell Personalized cell therapy UCLA
Pre-IND/IDE or Equivalent
Blood Cancer Adult Stem Cell Gene-modified, donor cell therapy Angiocrine
Clinical Trial, Phase 1 or Phase 1/2
Hemophilia A Adult Stem Cell Gene modification COH
Development Candidate, Proof of Concept
Immune Disease,
Severe Combined Immunodeficiency, Adenosine deaminase-deficient (ADA-SCID)
Adult Stem Cell Gene-modified, personalized cell therapy Orchard Therapeutics
Clinical Trial, Phase 2
Sarcoma Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Clinical Trial, Phase 1 or Phase 1/2
Type 1 diabetes Adult Stem Cell Personalized cell therapy Caladrius Biosciences
Clinical Trial, Phase 2
Lung Cancer Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Clinical Trial, Phase 1 or Phase 1/2
Leukocyte Adhesion Deficiency Adult Stem Cell Gene-modified, personalized cell therapy Rocket Pharmaceuticals, Inc.
Clinical Trial, Phase 1 or Phase 1/2
Amyotrophic Lateral Sclerosis Adult Stem Cell Gene-modified, donor cell therapy Cedars-Sinai
Clinical Trial, Phase 1 or Phase 1/2
Sickle Cell Disease Adult Stem Cell Gene-modified, personalized cell therapy Stanford
IND
Bone or Cartilage Disease Adult Stem Cell Small molecule therapy MAX BioPharma
Pre-IND/IDE or Equivalent
HIV-related Lymphoma,
HIV/AIDS
Adult Stem Cell Gene-modified, personalized cell therapy UC Davis
Clinical Trial, Phase 1 or Phase 1/2
Type 1 diabetes Adult Stem Cell Donor cell therapy UCSF
Clinical Trial, Phase 1 or Phase 1/2
Immune Disease,
Severe Combined Immunodeficiency, X-linked (X-SCID)
Adult Stem Cell Gene-modified, personalized cell therapy St. Jude
Clinical Trial, Phase 1 or Phase 1/2
Sickle Cell Disease Adult Stem Cell Gene-modified, personalized cell therapy UCSF
Pre-IND/IDE or Equivalent
Skeletal/Smooth Muscle disorders Adult Stem Cell Small molecule therapy Stanford
Development Candidate
Immune Disease,
X-linked Chronic Granulomatous Disease
Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Clinical Trial, Phase 1 or Phase 1/2
Cystinosis,
Kidney Failure
Adult Stem Cell Gene-modified, personalized cell therapy UCSD
Clinical Trial, Phase 1 or Phase 1/2
Skeletal/Smooth Muscle disorders Adult Stem Cell Protein/peptide therapy Stanford
Research Insights
Kidney Failure Adult Stem Cell Biologic Humacyte
Clinical Trial, Phase 3
Hearing Loss Adult Stem Cell Protein/peptide therapy Stanford
Development Candidate, Proof of Concept
Blood Disorders,
Leukemia
Adult Stem Cell Exploring stem cell mechanisms UCLA
Development Candidate, Proof of Concept, Research Insights
Brain Cancer,
Breast Cancer
Adult Stem Cell Gene-modified, personalized cell therapy COH
Clinical Trial, Phase 1 or Phase 1/2
Leukemia, Acute Myeloid (AML) Cancer Stem Cell Antibody Forty Seven
Clinical Trial, Phase 1 or Phase 1/2
Leukemia, Acute Myeloid (AML) Cancer Stem Cell Gene-modified, personalized cell therapy UCSF
Pre-IND/IDE or Equivalent
Leukemia, Acute Myeloid (AML) Cancer Stem Cell Antibody UCSD
Development Candidate, Proof of Concept
Leukemia, Acute Myeloid (AML) Cancer Stem Cell Antibody Cellerant Therapeutics
IND
Leukemia, Acute Myeloid (AML) Cancer Stem Cell Small molecule therapy UCSD
Pre-IND/IDE or Equivalent
Colon Cancer Cancer Stem Cell Antibody Forty Seven
Clinical Trial, Phase 1 or Phase 1/2
Cancer Cancer Stem Cell Gene-modified, personalized cell therapy UCSD
Pre-IND/IDE or Equivalent
B cell cancers,
Leukemia
Cancer Stem Cell Antibody UCSD
Clinical Trial, Phase 1 or Phase 1/2
Colon Cancer Cancer Stem Cell Small molecule therapy UCSD
Development Candidate, Proof of Concept
B cell cancers,
Leukemia
Cancer Stem Cell Antibody COH
Development Candidate, Proof of Concept
Liver Disease Directly Reprogrammed Cell Gene modification UCSF
Development Candidate
Muscular Dystrophy Embryonic Stem Cell,
iPS Cell
Personalized cell therapy UCLA
Development Candidate
Age-related macular degeneration Embryonic Stem Cell Biologic USC
Pre-IND/IDE or Equivalent
Traumatic Brain Injury Embryonic Stem Cell Donor cell therapy UC Irvine
Pre-IND/IDE or Equivalent
Spinal Cord Injury Embryonic Stem Cell Donor cell therapy UCSD
Pre-IND/IDE or Equivalent
Other Embryonic Stem Cell,
iPS Cell
Cell processing & handling X-Therma
Proof of Concept, Tool/Resources/Bottleneck
Stroke Embryonic Stem Cell Donor cell therapy Stanford
IND
Huntington's Disease Embryonic Stem Cell Donor cell therapy UC Irvine
IND
Leukemia, Acute Myeloid (AML) Embryonic Stem Cell Donor cell therapy UCSD
Pre-IND/IDE or Equivalent
Amyotrophic Lateral Sclerosis,
Spinal Cord Injury
Embryonic Stem Cell,
iPS Cell
Cell imaging & tracking UCSD
Research Insights

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