Active Awards Portfolio Dashboard

It takes a lot of effort to develop a promising stem cell research idea into an effective treatment that can help patients. CIRM funds a pipeline of projects spanning discovery, translation and clinical stage research. Check out our portfolio of active research awards in our interactive dashboard below. For a detailed list of CIRM-funded clinical trials, visit our Clinical Trials Dashboard.

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Disease Cell Typesort descending Therapeutic or Technology Institution Stage Project Objective Details
Skeletal/Smooth Muscle disorders Adult Stem Cell Protein/peptide therapy Stanford
Research Insights
Corneal Damage Adult Stem Cell Personalized cell therapy UCLA
Clinical Trial, Phase 1 or Phase 1/2
Amyotrophic Lateral Sclerosis Adult Stem Cell Personalized cell therapy BrainStorm
Clinical Trial, Phase 3
Bone or Cartilage Disease Adult Stem Cell Donor cell therapy UCLA
Proof of Concept
Severe Combined Immunodeficiency, Artemis deficient (ART-SCID) Adult Stem Cell Gene-modified, personalized cell therapy UCSF
Clinical Trial, Phase 1 or Phase 1/2
Osteonecrosis Adult Stem Cell Small molecule therapy UC Davis
Clinical Trial, Phase 1 or Phase 1/2
Cancer Adult Stem Cell Gene-modified, donor cell therapy UCLA
Development Candidate, Proof of Concept
Kidney Failure Adult Stem Cell Biologic Humacyte
Clinical Trial, Phase 3
Kidney Failure Adult Stem Cell Donor cell therapy Stanford
Clinical Trial, Phase 1 or Phase 1/2
Blood Cancer Adult Stem Cell Gene-modified, donor cell therapy Angiocrine
Clinical Trial, Phase 1 or Phase 1/2
B cell cancers,
Leukemia
Adult Stem Cell Gene-modified, personalized cell therapy Stanford
Clinical Trial, Phase 1 or Phase 1/2
Severe Combined Immunodeficiency, X-linked (X-SCID) Adult Stem Cell Antibody Stanford
Clinical Trial, Phase 1 or Phase 1/2
Hyper IgM Syndrome,
Immune Disease
Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Pre-IND/IDE or Equivalent
Hemophilia A Adult Stem Cell Gene modification COH
Development Candidate, Proof of Concept
Beta Thalassemia Adult Stem Cell Gene-modified, personalized cell therapy Sangamo
Clinical Trial, Phase 1 or Phase 1/2
Intestinal Disease Adult Stem Cell Personalized cell therapy CHLA
Development Candidate, Proof of Concept
Sickle Cell Disease Adult Stem Cell Gene-modified, personalized cell therapy CHORI
Pre-IND/IDE or Equivalent
Intervertebral disc degeneration Adult Stem Cell Personalized cell therapy Ankasa
IND
Ovarian Cancer Adult Stem Cell Gene-modified, donor cell therapy COH
Pre-IND/IDE or Equivalent
Sickle Cell Disease Adult Stem Cell Gene-modified, personalized cell therapy Stanford
IND
Immune Disease,
Severe Combined Immunodeficiency, Adenosine deaminase-deficient (ADA-SCID)
Adult Stem Cell Gene-modified, personalized cell therapy Orchard Therapeutics
Clinical Trial, Phase 2
Sickle Cell Disease Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Clinical Trial, Phase 1 or Phase 1/2
Pulmonary Hypertension,
Vascular Disease
Adult Stem Cell Donor cell therapy Cedars-Sinai
Clinical Trial, Phase 1 or Phase 1/2
Sickle Cell Disease Adult Stem Cell Gene-modified, personalized cell therapy UCSF
IND
Multiple Myeloma Adult Stem Cell Personalized cell therapy UCLA
Pre-IND/IDE or Equivalent
Lung Cancer Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Clinical Trial, Phase 1 or Phase 1/2
Sarcoma Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Clinical Trial, Phase 1 or Phase 1/2
Leukemia, Acute Myeloid (AML) Cancer Stem Cell Antibody Forty Seven
Clinical Trial, Phase 1 or Phase 1/2
Leukemia, Acute Myeloid (AML) Cancer Stem Cell Antibody UCSD
Development Candidate, Proof of Concept
Leukemia, Acute Myeloid (AML) Cancer Stem Cell Gene-modified, personalized cell therapy UCSF
Pre-IND/IDE or Equivalent
Leukemia, Acute Myeloid (AML) Cancer Stem Cell Antibody Cellerant Therapeutics
IND
Leukemia, Acute Myeloid (AML) Cancer Stem Cell Small molecule therapy UCSD
Pre-IND/IDE or Equivalent
Cancer Cancer Stem Cell Gene-modified, personalized cell therapy UCSD
Pre-IND/IDE or Equivalent
Ovarian Cancer Cancer Stem Cell Nucleic acid based therapy Loma Linda University
Proof of Concept
B cell cancers,
Leukemia
Cancer Stem Cell Antibody COH
Development Candidate, Proof of Concept
B cell cancers,
Leukemia
Cancer Stem Cell Antibody UCSD
Clinical Trial, Phase 1 or Phase 1/2
Colon Cancer Cancer Stem Cell Small molecule therapy COH
Development Candidate, Proof of Concept
Colon Cancer Cancer Stem Cell Antibody Forty Seven
Clinical Trial, Phase 1 or Phase 1/2
Respiratory Disorders Directly Reprogrammed Cell Model system development UCSF
Research Insights
Liver Disease Directly Reprogrammed Cell Gene modification UCSF
Development Candidate
Epilepsy Embryonic Stem Cell Donor cell therapy Neurona Therapeutics
Pre-IND/IDE or Equivalent
Amyotrophic Lateral Sclerosis,
Spinal Cord Injury
Embryonic Stem Cell,
iPS Cell
Cell imaging & tracking UCSD
Research Insights
Liver Disease Embryonic Stem Cell Donor cell therapy Stanford
Development Candidate, Proof of Concept
Spinal Cord Injury Embryonic Stem Cell Donor cell therapy Lineage Cell
Clinical Trial, Phase 1 or Phase 1/2
Bladder or Urinary Tract Disorder,
Solid Tumors
Embryonic Stem Cell Donor cell therapy Stanford
Development Candidate, Proof of Concept
Huntington's Disease Embryonic Stem Cell Gene-modified, donor cell therapy UC Irvine
Development Candidate, Proof of Concept
Other Embryonic Stem Cell,
iPS Cell
Cell processing & handling X-Therma
Proof of Concept, Tool/Resources/Bottleneck
Muscular Dystrophy Embryonic Stem Cell,
iPS Cell
Personalized cell therapy UCLA
Development Candidate
Retinitis Pigmentosa Embryonic Stem Cell Donor cell therapy UC Irvine
Pre-IND/IDE or Equivalent
Cancer Embryonic Stem Cell Specific Cell Type Derivation UCLA
Tool/Resources/Bottleneck

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