Active Awards Portfolio Dashboard

It takes a lot of effort to develop a promising stem cell research idea into an effective treatment that can help patients. CIRM funds a pipeline of projects spanning discovery, translation and clinical stage research. Check out our portfolio of active research awards in our interactive dashboard below. For a detailed list of CIRM-funded clinical trials, visit our Clinical Trials Dashboard.

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Disease Cell Typesort descending Therapeutic or Technology Institution Stage Project Objective Details
Multiple Myeloma Adult Stem Cell Personalized cell therapy UCLA
Pre-IND/IDE or Equivalent
Osteonecrosis Adult Stem Cell Small molecule therapy UC Davis
Clinical Trial, Phase 1 or Phase 1/2
COVID-19 Adult Stem Cell Vaccine UCLA
Development Candidate, Proof of Concept
Blood Disorders Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Development Candidate, Proof of Concept
Severe Combined Immunodeficiency, Artemis deficient (ART-SCID) Adult Stem Cell Gene-modified, personalized cell therapy UCSF
Clinical Trial, Phase 1 or Phase 1/2
Sickle Cell Disease Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Clinical Trial, Phase 1 or Phase 1/2
COVID-19 Adult Stem Cell Small molecule therapy UCLA
Pre-IND/IDE or Equivalent
Alpha Thalassemia Major Adult Stem Cell Donor cell therapy UCSF
Clinical Trial, Phase 1 or Phase 1/2
B cell cancers,
Leukemia
Adult Stem Cell Gene-modified, personalized cell therapy Stanford
Clinical Trial, Phase 1 or Phase 1/2
Type 1 diabetes Adult Stem Cell Donor cell therapy UCSF
Clinical Trial, Phase 1 or Phase 1/2
COVID-19,
Respiratory Disorders
Adult Stem Cell Donor cell therapy Celularity Inc
Clinical Trial, Phase 1 or Phase 1/2
Inflammatory bowel disease Adult Stem Cell Donor cell therapy Vitabolus, Inc.
Development Candidate, Proof of Concept
Beta Thalassemia Adult Stem Cell Gene-modified, personalized cell therapy Sangamo
Clinical Trial, Phase 1 or Phase 1/2
Cystinosis,
Kidney Failure
Adult Stem Cell Gene-modified, personalized cell therapy UCSD
Clinical Trial, Phase 1 or Phase 1/2
Sickle Cell Disease Adult Stem Cell Gene-modified, personalized cell therapy UCSF
Pre-IND/IDE or Equivalent
Amyotrophic Lateral Sclerosis Adult Stem Cell Personalized cell therapy BrainStorm
Clinical Trial, Phase 3
Immune Disease,
Severe Combined Immunodeficiency, Adenosine deaminase-deficient (ADA-SCID)
Adult Stem Cell Gene-modified, personalized cell therapy Orchard Therapeutics
Clinical Trial, Phase 2
Brain Cancer,
Breast Cancer
Adult Stem Cell Gene-modified, personalized cell therapy COH
Clinical Trial, Phase 1 or Phase 1/2
HIV/AIDS Adult Stem Cell Gene-modified, personalized cell therapy COH
Clinical Trial, Phase 1 or Phase 1/2
Blood Cancer Adult Stem Cell Gene-modified, donor cell therapy Angiocrine
Clinical Trial, Phase 1 or Phase 1/2
Lung Cancer Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Clinical Trial, Phase 1 or Phase 1/2
Hearing Loss Adult Stem Cell Protein/peptide therapy Stanford
Development Candidate, Proof of Concept
HIV-related Lymphoma,
HIV/AIDS
Adult Stem Cell Gene-modified, personalized cell therapy UC Davis
Clinical Trial, Phase 1 or Phase 1/2
Leukemia, Acute Myeloid (AML) Cancer Stem Cell Gene-modified, personalized cell therapy UCSF
Pre-IND/IDE or Equivalent
Leukemia, Acute Myeloid (AML) Cancer Stem Cell Small molecule therapy UCSD
Pre-IND/IDE or Equivalent
Colon Cancer Cancer Stem Cell Small molecule therapy UCSD
Development Candidate, Proof of Concept
Cancer Cancer Stem Cell Gene-modified, personalized cell therapy UCSD
Pre-IND/IDE or Equivalent
B cell cancers,
Leukemia
Cancer Stem Cell Antibody UCSD
Clinical Trial, Phase 1 or Phase 1/2
Traumatic Brain Injury Embryonic Stem Cell Donor cell therapy UC Irvine
Pre-IND/IDE or Equivalent
Epilepsy Embryonic Stem Cell Donor cell therapy Neurona Therapeutics
Research Insights
Type 1 diabetes Embryonic Stem Cell Donor cell therapy ViaCyte
Clinical Trial, Phase 1 or Phase 1/2
Retinitis Pigmentosa Embryonic Stem Cell Donor cell therapy UC Irvine
Pre-IND/IDE or Equivalent
Spinal Cord Injury Embryonic Stem Cell Donor cell therapy UCSD
Pre-IND/IDE or Equivalent
Traumatic Brain Injury Embryonic Stem Cell Exosomes based therapy UC Irvine
Development Candidate, Proof of Concept, Research Insights
Spinal Cord Injury Embryonic Stem Cell Therapeutic Approach UCSD
Development Candidate, Research Insights
Huntington's Disease Embryonic Stem Cell Donor cell therapy UC Irvine
IND
Leukemia, Acute Myeloid (AML) Embryonic Stem Cell Donor cell therapy UCSD
Pre-IND/IDE or Equivalent
Stroke Embryonic Stem Cell Donor cell therapy Stanford
IND
Epilepsy Embryonic Stem Cell Donor cell therapy Neurona Therapeutics
Pre-IND/IDE or Equivalent
Type 1 diabetes Embryonic Stem Cell Gene-modified, donor cell therapy Lundquist Institute
Development Candidate, Proof of Concept
Amyotrophic Lateral Sclerosis,
Spinal Cord Injury
Embryonic Stem Cell,
iPS Cell
Cell imaging & tracking UCSD
Research Insights
Spinal Cord Injury Embryonic Stem Cell Donor cell therapy Lineage Cell
Clinical Trial, Phase 1 or Phase 1/2
Neurological Disorders Embryonic Stem Cell Donor cell therapy UC Irvine
Development Candidate, Proof of Concept
Bladder or Urinary Tract Disorder,
Solid Tumors
Embryonic Stem Cell Donor cell therapy Stanford
Development Candidate, Proof of Concept
Embryonic Stem Cell Cell processing & handling Stanford
Research Insights
Age-related macular degeneration Embryonic Stem Cell Biologic USC
Pre-IND/IDE or Equivalent
Stroke iPS Cell Donor cell therapy UCLA
Development Candidate, Proof of Concept
Intestinal Disease,
Neurological Disorders
iPS Cell Donor cell therapy CHLA
Pre-IND/IDE or Equivalent
COVID-19 iPS Cell Small molecule therapy UCSD
Development Candidate, Proof of Concept
Age-related macular degeneration iPS Cell Personalized cell therapy UCLA
Pre-IND/IDE or Equivalent

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