Active Awards Portfolio Dashboard

It takes a lot of effort to develop a promising stem cell research idea into an effective treatment that can help patients. CIRM funds a pipeline of projects spanning discovery, translation and clinical stage research. Check out our portfolio of active research awards in our interactive dashboard below. For a detailed list of CIRM-funded clinical trials, visit our Clinical Trials Dashboard.

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Disease Cell Type Therapeutic or Technologysort descending Institution Stage Project Objective Details
Brain Cancer,
Neurological Disorders
Embryonic Stem Cell Exosomes based therapy UC Irvine
Development Candidate, Proof of Concept
Traumatic Brain Injury Embryonic Stem Cell Exosomes based therapy UC Irvine
Development Candidate, Proof of Concept, Research Insights
Heart failure iPS Cell Exosomes based therapy Stanford
Development Candidate, Proof of Concept
Hemophilia A Adult Stem Cell Gene modification COH
Development Candidate, Proof of Concept
IPEX Syndrome,
Immune Disease
Vital Research Opportunity Gene Therapy, cell free Stanford
IND
Parkinson's Disease Vital Research Opportunity Gene Therapy, cell free Brain Neurotherapy Bio
Clinical Trial, Phase 1 or Phase 1/2
Angelman Syndrome,
Autism
iPS Cell Gene Therapy, cell free UC Davis
Development Candidate, Proof of Concept
Duchenne Muscular Dystrophy Somatic Cell Gene Therapy, cell free MyoGene Bio LLC
Pre-IND/IDE or Equivalent
Amyotrophic Lateral Sclerosis Adult Stem Cell Gene-modified, donor cell therapy Cedars-Sinai
Clinical Trial, Phase 1 or Phase 1/2
Liver Disease iPS Cell Gene-modified, donor cell therapy CHLA
Development Candidate, Proof of Concept
Amyotrophic Lateral Sclerosis Adult Stem Cell Gene-modified, donor cell therapy Cedars-Sinai
Clinical Trial, Phase 1 or Phase 1/2
COVID-19 Adult Stem Cell Gene-modified, donor cell therapy UCLA
Development Candidate, Proof of Concept
COVID-19 Embryonic Stem Cell,
iPS Cell
Gene-modified, donor cell therapy COH
Proof of Concept
Spinal Cord Injury Embryonic Stem Cell Gene-modified, donor cell therapy UCSD
Development Candidate, Research Insights
Ovarian Cancer Adult Stem Cell Gene-modified, donor cell therapy COH
Pre-IND/IDE or Equivalent
Blood Cancer Adult Stem Cell Gene-modified, donor cell therapy Angiocrine
Clinical Trial, Phase 1 or Phase 1/2
Parkinson's Disease Adult Stem Cell Gene-modified, donor cell therapy UCSF
IND
Ovarian Cancer iPS Cell Gene-modified, donor cell therapy UCSD
Development Candidate, Proof of Concept
Ovarian Cancer iPS Cell Gene-modified, donor cell therapy UCSD
Development Candidate, Proof of Concept
Multiple Myeloma Adult Stem Cell Gene-modified, donor cell therapy UCLA
Pre-IND/IDE or Equivalent
Type 1 diabetes Embryonic Stem Cell Gene-modified, donor cell therapy Lundquist Institute
Development Candidate, Proof of Concept
Blood Disorders,
Immune Disease
Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Proof of Concept
Canavan Disease iPS Cell Gene-modified, personalized cell therapy COH
Pre-IND/IDE or Equivalent
Brain Cancer Adult Stem Cell Gene-modified, personalized cell therapy Stanford
Clinical Trial, Phase 1 or Phase 1/2
Severe Combined Immunodeficiency, Artemis deficient (ART-SCID) Adult Stem Cell Gene-modified, personalized cell therapy UCSF
Clinical Trial, Phase 1 or Phase 1/2
Leukemia, Acute Myeloid (AML) Cancer Stem Cell Gene-modified, personalized cell therapy UCSF
Pre-IND/IDE or Equivalent
Immune Disease,
Severe Combined Immunodeficiency, X-linked (X-SCID)
Adult Stem Cell Gene-modified, personalized cell therapy St. Jude
Clinical Trial, Phase 1 or Phase 1/2
B cell cancers,
Leukemia
Adult Stem Cell Gene-modified, personalized cell therapy Stanford
Clinical Trial, Phase 1 or Phase 1/2
IPEX Syndrome Adult Stem Cell Gene-modified, personalized cell therapy ImmunoVec
Pre-IND/IDE or Equivalent
Sickle Cell Disease Adult Stem Cell Gene-modified, personalized cell therapy Boston Children's Hospital
Clinical Trial, Phase 2
Immune Disease,
Severe Combined Immunodeficiency, Adenosine deaminase-deficient (ADA-SCID)
Adult Stem Cell Gene-modified, personalized cell therapy Orchard Therapeutics
Clinical Trial, Phase 2
Brain Cancer Somatic Cell Gene-modified, personalized cell therapy UCSF
Pre-IND/IDE or Equivalent
Hyper IgM Syndrome,
Immune Disease
Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Pre-IND/IDE or Equivalent
Lung Cancer Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Clinical Trial, Phase 1 or Phase 1/2
Metabolic Disorders Somatic Cell Gene-modified, personalized cell therapy Immusoft Corporation
Pre-IND/IDE or Equivalent
Sickle Cell Disease Adult Stem Cell Gene-modified, personalized cell therapy UCSF
IND
HIV/AIDS,
Immune Disease
Adult Stem Cell Gene-modified, personalized cell therapy UCSF
Clinical Trial, Phase 1 or Phase 1/2
Sickle Cell Disease Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Clinical Trial, Phase 1 or Phase 1/2
Sarcoma Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Clinical Trial, Phase 1 or Phase 1/2
Bone or Cartilage Disease Adult Stem Cell Gene-modified, personalized cell therapy Rocket Pharmaceuticals, Inc.
Clinical Trial, Phase 1 or Phase 1/2
Epidermolysis Bullosa iPS Cell Gene-modified, personalized cell therapy Stanford
Development Candidate, Proof of Concept
B cell cancers Somatic Cell Gene-modified, personalized cell therapy UCSF
Pre-IND/IDE or Equivalent
Immune Disease,
Leukocyte Adhesion Deficiency
Adult Stem Cell Gene-modified, personalized cell therapy Rocket Pharmaceuticals, Inc.
Clinical Trial, Phase 1 or Phase 1/2
HIV/AIDS Adult Stem Cell Gene-modified, personalized cell therapy COH
Clinical Trial, Phase 1 or Phase 1/2
Brain Cancer Adult Stem Cell Gene-modified, personalized cell therapy COH
Clinical Trial, Phase 1 or Phase 1/2
Brain Cancer Adult Stem Cell Gene-modified, personalized cell therapy COH
Clinical Trial, Phase 1 or Phase 1/2
Brain Cancer Adult Stem Cell Gene-modified, personalized cell therapy COH
IND
HIV-related Lymphoma,
HIV/AIDS
Adult Stem Cell Gene-modified, personalized cell therapy UC Davis
Clinical Trial, Phase 1 or Phase 1/2
Brain Cancer Somatic Cell Gene-modified, personalized cell therapy UCSF
Pre-IND/IDE or Equivalent
Brain Cancer Adult Stem Cell Gene-modified, personalized cell therapy UCSF
Development Candidate, Proof of Concept

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