Active Awards Portfolio Dashboard

It takes a lot of effort to develop a promising stem cell research idea into an effective treatment that can help patients. CIRM funds a pipeline of projects spanning discovery, translation and clinical stage research. Check out our portfolio of active research awards in our interactive dashboard below. For a detailed list of CIRM-funded clinical trials, visit our Clinical Trials Dashboard.

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Disease Cell Typesort descending Therapeutic or Technology Institution Stage Project Objective Details
Sickle Cell Disease Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Clinical Trial, Phase 1 or Phase 1/2
Beta Thalassemia,
Sickle Cell Disease
Adult Stem Cell Diagnostic Test UCSF
Regulated Lab Test, Ready for Validation
Immune Disease,
Leukocyte Adhesion Deficiency
Adult Stem Cell Gene-modified, personalized cell therapy Rocket Pharmaceuticals, Inc.
Clinical Trial, Phase 1 or Phase 1/2
Bone or Cartilage Disease Adult Stem Cell Gene-modified, personalized cell therapy Rocket Pharmaceuticals, Inc.
Clinical Trial, Phase 1 or Phase 1/2
Parkinson's Disease Adult Stem Cell Gene-modified, donor cell therapy UCSF
IND
Type 1 diabetes Adult Stem Cell Donor cell therapy UCSF
Clinical Trial, Phase 1 or Phase 1/2
Spina Bifida Adult Stem Cell Donor cell therapy UC Davis
Clinical Trial, Phase 1 or Phase 1/2
HIV/AIDS Adult Stem Cell Gene-modified, personalized cell therapy COH
Clinical Trial, Phase 1 or Phase 1/2
Brain Cancer Adult Stem Cell Gene-modified, personalized cell therapy COH
Clinical Trial, Phase 1 or Phase 1/2
Brain Cancer Adult Stem Cell Gene-modified, personalized cell therapy COH
Clinical Trial, Phase 1 or Phase 1/2
Brain Cancer Adult Stem Cell Gene-modified, personalized cell therapy COH
IND
Cystinosis,
Kidney Failure
Adult Stem Cell Gene-modified, personalized cell therapy UCSD
Clinical Trial, Phase 1 or Phase 1/2
HIV-related Lymphoma,
HIV/AIDS
Adult Stem Cell Gene-modified, personalized cell therapy UC Davis
Clinical Trial, Phase 1 or Phase 1/2
Blood Cancer,
Bone Marrow Transplant and Viral Infection
Adult Stem Cell Donor cell therapy CHLA
Clinical Trial, Phase 1 or Phase 1/2
Amyotrophic Lateral Sclerosis Adult Stem Cell Donor cell therapy UCSD
Development Candidate, Proof of Concept
Brain Cancer Adult Stem Cell Gene-modified, personalized cell therapy UCSF
Development Candidate, Proof of Concept
Brain Cancer,
Breast Cancer
Adult Stem Cell Gene-modified, personalized cell therapy COH
Clinical Trial, Phase 1 or Phase 1/2
COVID-19 Adult Stem Cell Donor cell therapy UCSF
Clinical Trial, Phase 2
Blood Disorders Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Development Candidate, Proof of Concept
Immune Disease,
X-linked Chronic Granulomatous Disease
Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Clinical Trial, Phase 1 or Phase 1/2
Multiple Myeloma Adult Stem Cell Gene-modified, donor cell therapy UCLA
Pre-IND/IDE or Equivalent
Multiple Myeloma Adult Stem Cell Gene-modified, personalized cell therapy Poseida Therapeutics
Clinical Trial, Phase 1 or Phase 1/2
Ovarian Cancer Adult Stem Cell Gene-modified, personalized cell therapy COH
Development Candidate, Proof of Concept
Sickle Cell Disease Adult Stem Cell Donor cell therapy ExCellThera Inc.
Clinical Trial, Phase 1 or Phase 1/2
Melanoma Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Pre-IND/IDE or Equivalent
Sickle Cell Disease Adult Stem Cell Gene-modified, personalized cell therapy UCSF
Clinical Trial, Phase 1 or Phase 1/2
Heart Disease,
Danon Disease
Adult Stem Cell Gene-modified, personalized cell therapy UCSD
Development Candidate, Proof of Concept
Leukemia, Acute Myeloid (AML) Cancer Stem Cell Small molecule therapy UCSD
Pre-IND/IDE or Equivalent
Leukemia, Acute Myeloid (AML) Cancer Stem Cell Gene-modified, personalized cell therapy UCSF
Pre-IND/IDE or Equivalent
Pancreatic Cancer Cancer Stem Cell Small molecule therapy UCSD
Development Candidate, Proof of Concept
B cell cancers,
Leukemia
Cancer Stem Cell Antibody UCSD
Clinical Trial, Phase 1 or Phase 1/2
Leukemia, Acute Myeloid (AML) Cancer Stem Cell Antibody Immune-Onc Therapeutics
Clinical Trial, Phase 1 or Phase 1/2
Traumatic Brain Injury Embryonic Stem Cell Donor cell therapy UC Irvine
Pre-IND/IDE or Equivalent
Spinal Cord Injury Embryonic Stem Cell Donor cell therapy UCSD
Pre-IND/IDE or Equivalent
Neurological Disorders Embryonic Stem Cell Donor cell therapy UC Irvine
Development Candidate, Proof of Concept
Stroke Embryonic Stem Cell Donor cell therapy Stanford
Clinical Trial, Phase 1 or Phase 1/2
Leukemia, Acute Myeloid (AML) Embryonic Stem Cell Donor cell therapy UCSD
Pre-IND/IDE or Equivalent
Cartilage defect Embryonic Stem Cell Donor cell therapy USC
IND
Heart failure Embryonic Stem Cell Donor cell therapy Stanford
Clinical Trial, Phase 1 or Phase 1/2
Muscular Dystrophy Embryonic Stem Cell Protein/peptide therapy Juvena Therapeutics Inc
Pre-IND/IDE or Equivalent
Stroke Embryonic Stem Cell Donor cell therapy UCLA
Pre-IND/IDE or Equivalent
Huntington's Disease Embryonic Stem Cell Donor cell therapy UC Irvine
IND
Brain Cancer,
Neurological Disorders
Embryonic Stem Cell Exosomes based therapy UC Irvine
Development Candidate, Proof of Concept
Traumatic Brain Injury Embryonic Stem Cell Exosomes based therapy UC Irvine
Development Candidate, Proof of Concept, Research Insights
Spinal Cord Injury Embryonic Stem Cell Gene-modified, donor cell therapy UCSD
Development Candidate, Research Insights
Retinitis Pigmentosa Embryonic Stem Cell Donor cell therapy UC Irvine
Pre-IND/IDE or Equivalent
Embryonic Stem Cell Cell processing & handling Stanford
Research Insights
Amyotrophic Lateral Sclerosis,
Spinal Cord Injury
Embryonic Stem Cell,
iPS Cell
Cell imaging & tracking UCSD
Research Insights
Type 1 diabetes Embryonic Stem Cell Donor cell therapy ViaCyte
Clinical Trial, Phase 1 or Phase 1/2
Age-related macular degeneration Embryonic Stem Cell Biologic USC
Pre-IND/IDE or Equivalent

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