Active Awards Portfolio Dashboard

It takes a lot of effort to develop a promising stem cell research idea into an effective treatment that can help patients. CIRM funds a pipeline of projects spanning discovery, translation and clinical stage research. Check out our portfolio of active research awards in our interactive dashboard below. For a detailed list of CIRM-funded clinical trials, visit our Clinical Trials Dashboard.

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Disease Cell Type Therapeutic or Technologysort descending Institution Stage Project Objective Details
Huntington's Disease Embryonic Stem Cell Donor cell therapy UC Irvine
IND
Retinitis Pigmentosa Adult Stem Cell Donor cell therapy Cedars-Sinai
Clinical Trial, Phase 1 or Phase 1/2
Bone or Cartilage Disease Adult Stem Cell Donor cell therapy UCLA
Proof of Concept
Spinal Cord Injury Embryonic Stem Cell Donor cell therapy Lineage Cell
Clinical Trial, Phase 1 or Phase 1/2
Kidney Failure Adult Stem Cell Donor cell therapy Stanford
Clinical Trial, Phase 1 or Phase 1/2
Dementia iPS Cell Donor cell therapy Gladstone
Development Candidate, Proof of Concept
Liver Disease Adult Stem Cell Donor cell therapy Stanford
Development Candidate
Heart Disease iPS Cell Donor cell therapy Stanford
Development Candidate, Proof of Concept
Age-related macular degeneration iPS Cell Exploring disease mechanisms UCSD
Research Insights
Blood Disorders,
Leukemia
Adult Stem Cell Exploring stem cell mechanisms UCLA
Development Candidate, Proof of Concept, Research Insights
Liver Disease Directly Reprogrammed Cell Gene modification UCSF
Development Candidate
Hemophilia A Adult Stem Cell Gene modification COH
Development Candidate, Proof of Concept
IPEX Syndrome,
Immune Disease
Gene Therapy, cell free Stanford
IND
Parkinson's Disease Gene Therapy, cell free Brain Neurotherapy Bio
Clinical Trial, Phase 1 or Phase 1/2
Type 1 diabetes Embryonic Stem Cell Gene-modified, donor cell therapy Salk
Development Candidate, Proof of Concept
Huntington's Disease Embryonic Stem Cell Gene-modified, donor cell therapy UC Irvine
Development Candidate, Proof of Concept
Type 1 diabetes Embryonic Stem Cell Gene-modified, donor cell therapy UCSD
Development Candidate, Proof of Concept
Ovarian Cancer Adult Stem Cell Gene-modified, donor cell therapy COH
Pre-IND/IDE or Equivalent
Type 1 diabetes Embryonic Stem Cell Gene-modified, donor cell therapy ViaCyte
Development Candidate
Liver Disease iPS Cell Gene-modified, donor cell therapy CHLA
Development Candidate, Proof of Concept
Parkinson's Disease Adult Stem Cell Gene-modified, donor cell therapy UCSF
IND
Amyotrophic Lateral Sclerosis Adult Stem Cell Gene-modified, donor cell therapy Cedars-Sinai
Clinical Trial, Phase 1 or Phase 1/2
Stroke Adult Stem Cell Gene-modified, donor cell therapy SanBio, Inc.
Clinical Trial, Phase 2
Solid Tumors iPS Cell Gene-modified, donor cell therapy Fate Therapeutics
IND
Blood Cancer Adult Stem Cell Gene-modified, donor cell therapy Angiocrine
Clinical Trial, Phase 1 or Phase 1/2
Cancer Adult Stem Cell Gene-modified, donor cell therapy UCLA
Development Candidate, Proof of Concept
Beta Thalassemia Adult Stem Cell Gene-modified, personalized cell therapy Sangamo
Clinical Trial, Phase 1 or Phase 1/2
Hyper IgM Syndrome,
Immune Disease
Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Pre-IND/IDE or Equivalent
Immune Disease,
Severe Combined Immunodeficiency, Adenosine deaminase-deficient (ADA-SCID)
Adult Stem Cell Gene-modified, personalized cell therapy Orchard Therapeutics
Clinical Trial, Phase 2
Sickle Cell Disease Adult Stem Cell Gene-modified, personalized cell therapy UCSF
IND
Hyper IgM Syndrome Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Development Candidate, Proof of Concept
Lung Cancer Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Clinical Trial, Phase 1 or Phase 1/2
HIV-related Lymphoma,
HIV/AIDS
Adult Stem Cell Gene-modified, personalized cell therapy UC Davis
Clinical Trial, Phase 1 or Phase 1/2
Cystic Fibrosis Adult Stem Cell Gene-modified, personalized cell therapy Stanford
Development Candidate
Sarcoma Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Clinical Trial, Phase 1 or Phase 1/2
Immune Disease,
X-linked Chronic Granulomatous Disease
Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Clinical Trial, Phase 1 or Phase 1/2
Leukocyte Adhesion Deficiency Adult Stem Cell Gene-modified, personalized cell therapy Rocket Pharmaceuticals, Inc.
Clinical Trial, Phase 1 or Phase 1/2
Brain Cancer Adult Stem Cell Gene-modified, personalized cell therapy COH
Clinical Trial, Phase 1 or Phase 1/2
Cystinosis,
Kidney Failure
Adult Stem Cell Gene-modified, personalized cell therapy UCSD
Clinical Trial, Phase 1 or Phase 1/2
Canavan Disease iPS Cell Gene-modified, personalized cell therapy COH
Pre-IND/IDE or Equivalent
Brain Cancer,
Breast Cancer
Adult Stem Cell Gene-modified, personalized cell therapy COH
Clinical Trial, Phase 1 or Phase 1/2
Multiple Myeloma Adult Stem Cell Gene-modified, personalized cell therapy Poseida Therapeutics
Clinical Trial, Phase 1 or Phase 1/2
Multiple Myeloma Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Pre-IND/IDE or Equivalent
Epidermolysis Bullosa iPS Cell Gene-modified, personalized cell therapy Stanford
Pre-IND/IDE or Equivalent
HIV/AIDS Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Development Candidate, Proof of Concept
Brain Cancer Adult Stem Cell Gene-modified, personalized cell therapy COH
IND
Cystinosis Adult Stem Cell Gene-modified, personalized cell therapy UCSD
IND
Leukemia, Acute Myeloid (AML) Cancer Stem Cell Gene-modified, personalized cell therapy UCSF
Pre-IND/IDE or Equivalent
Prostate Cancer Adult Stem Cell Gene-modified, personalized cell therapy Poseida Therapeutics
IND
Immune Disease,
Severe Combined Immunodeficiency, X-linked (X-SCID)
Adult Stem Cell Gene-modified, personalized cell therapy St. Jude
Clinical Trial, Phase 1 or Phase 1/2

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