Active Awards Portfolio Dashboard

It takes a lot of effort to develop a promising stem cell research idea into an effective treatment that can help patients. CIRM funds a pipeline of projects spanning discovery, translation and clinical stage research. Check out our portfolio of active research awards in our interactive dashboard below. For a detailed list of CIRM-funded clinical trials, visit our Clinical Trials Dashboard.

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Disease

Therapeutic or Technology

Disease	Cell Type	Therapeutic or Technology	Institution	Project Objective
Leukemia, Acute Myeloid (AML)	Cancer Stem Cell	Antibody	Forty Seven	Clinical Trial, Phase 1 or Phase 1/2
Prostate Cancer	Cancer Stem Cell	Antibody	UCLA	Development Candidate
Leukemia, Acute Myeloid (AML)	Cancer Stem Cell	Antibody	Cellerant Therapeutics, Inc.	IND
B cell cancers, Leukemia	Cancer Stem Cell	Antibody	COH	Development Candidate, Proof of Concept
Immune Disease, Severe Combined Immunodeficiency, X-linked (X-SCID)	Adult Stem Cell	Antibody	Stanford	Clinical Trial, Phase 1 or Phase 1/2
B cell cancers, Leukemia	Cancer Stem Cell	Antibody	UCSD	Clinical Trial, Phase 1 or Phase 1/2
Leukemia, Acute Myeloid (AML)	Cancer Stem Cell	Antibody	UCSD	Development Candidate, Proof of Concept
Colon Cancer	Cancer Stem Cell	Antibody	Forty Seven	Clinical Trial, Phase 1 or Phase 1/2
Heart Disease	iPS Cell	Assay development	Stanford	Tool/Resources/Bottleneck
Neurological Disorders	Embryonic Stem Cell, iPS Cell	Assay development	Scripps	Tool/Resources/Bottleneck
Kidney Failure	Adult Stem Cell	Biologic	Humacyte	Clinical Trial, Phase 3
Vascular Disease	Adult Stem Cell	Biologic	UCSD	Pre-IND/IDE or Equivalent
Kidney Failure	Adult Stem Cell	Biologic	Humacyte	Clinical Trial, Phase 3
Bone or Cartilage Disease	Adult Stem Cell	Cell imaging & tracking	UC Davis	Tool/Resources/Bottleneck
Vascular Disease	Adult Stem Cell	Cell imaging & tracking	UC Davis	Tool/Resources/Bottleneck
Amyotrophic Lateral Sclerosis, Spinal Cord Injury	Embryonic Stem Cell, iPS Cell	Cell imaging & tracking	UCSD	Research Insights
Other	Adult Stem Cell	Cell imaging & tracking	Stanford	Tool/Resources/Bottleneck
Other	Embryonic Stem Cell	Cell imaging & tracking	UC Berkeley	Tool/Resources/Bottleneck
Vision Loss	iPS Cell	Cell processing & handling	UCSD	Tool/Resources/Bottleneck
Blood Disorders	Adult Stem Cell	Cell processing & handling	UCSF	Tool/Resources/Bottleneck
Other	Embryonic Stem Cell, iPS Cell	Cell processing & handling	UCLA	Development Candidate, Proof of Concept
Parkinson's Disease	iPS Cell	Cell processing & handling	Scaled Biolabs Inc.	Development Candidate
Liver Disease	iPS Cell	Cell processing & handling	USC	Tool/Resources/Bottleneck
Blood Disorders	Adult Stem Cell	Cell processing & handling	Stanford	Research Insights
Other	Embryonic Stem Cell, iPS Cell	Cell processing & handling	X-Therma	Proof of Concept, Tool/Resources/Bottleneck
Type 1 diabetes	Embryonic Stem Cell	Device	UCSF	Proof of Concept
Beta Thalassemia, Sickle Cell Disease	Adult Stem Cell	Diagnostic Test	CHORI	Regulated Lab Test, Ready for Validation
Cancer	Embryonic Stem Cell	Donor cell therapy	UCLA	Tool/Resources/Bottleneck
Heart Disease	Embryonic Stem Cell	Donor cell therapy	UCLA	Proof of Concept
Vascular Disease	iPS Cell	Donor cell therapy	PAVIR	Proof of Concept, Research Insights
Type 1 diabetes	Embryonic Stem Cell	Donor cell therapy	UCSF	Development Candidate
Bone or Cartilage Disease	iPS Cell	Donor cell therapy	Cedars-Sinai	Proof of Concept, Research Insights
Spinal Cord Injury	Adult Stem Cell	Donor cell therapy	UC Irvine	Development Candidate
Liver Disease	Adult Stem Cell	Donor cell therapy	Stanford	Development Candidate
Vision Loss	Embryonic Stem Cell	Donor cell therapy	USC	Proof of Concept, Research Insights
Traumatic Brain Injury	Embryonic Stem Cell	Donor cell therapy	UC Irvine	Development Candidate
Age-related macular degeneration	Embryonic Stem Cell	Donor cell therapy	USC	Clinical Trial, Phase 1 or Phase 1/2
Blood Cancer, Bone Marrow Transplant and Viral Infection	Adult Stem Cell	Donor cell therapy	CHLA	Clinical Trial, Phase 1 or Phase 1/2
Heart Disease	iPS Cell	Donor cell therapy	UCSF	Proof of Concept
Stroke	Embryonic Stem Cell	Donor cell therapy	Stanford	IND
Bone or Cartilage Disease	Adult Stem Cell	Donor cell therapy	UCLA	Proof of Concept
Age-related macular degeneration	Adult Stem Cell	Donor cell therapy	Stanford	Pre-IND/IDE or Equivalent
Spinal Cord Injury	Embryonic Stem Cell, iPS Cell	Donor cell therapy	UC Berkeley	Proof of Concept
Kidney Failure	Adult Stem Cell	Donor cell therapy	Medeor Therapeutics	Clinical Trial, Phase 3
Blood Cancer, Ovarian Cancer	iPS Cell	Donor cell therapy	UCSD	Development Candidate
Thymic Disorder, 22q11 Deletion/DiGeorge	Embryonic Stem Cell, iPS Cell	Donor cell therapy	Stanford	Development Candidate, Proof of Concept
Spina Bifida	Adult Stem Cell	Donor cell therapy	UC Davis	IND
Sickle Cell Disease	Adult Stem Cell	Donor cell therapy	COH	Clinical Trial, Phase 1 or Phase 1/2
Blood Cancer	Adult Stem Cell	Donor cell therapy	Angiocrine	Clinical Trial, Phase 1 or Phase 1/2
Alpha Thalassemia Major	Adult Stem Cell	Donor cell therapy	UCSF	Clinical Trial, Phase 1 or Phase 1/2

California's Stem Cell Agency

California Institute for Regenerative Medicine

Active Awards Portfolio Dashboard

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Aging
Arthritis
Blood Disorders
– Alpha Thalassemia Major
– Anemia
– Beta Thalassemia
– Bone Marrow Transplant and Viral Infection
– Hemophilia A
– Severe Combined Immunodeficiency, Adenosine deaminase-deficient (ADA-SCID)
– Severe Combined Immunodeficiency, Artemis deficient (ART-SCID)
– Severe Combined Immunodeficiency, X-linked (X-SCID)
– Sickle Cell Disease
– X-linked Chronic Granulomatous Disease
Bone or Cartilage Disease
– Osteoarthritis
– Osteonecrosis
Cancer
– Blood Cancer
–– Acute Myeloid Leukemia
–– B cell cancers
–– HIV-related Lymphoma
–– Leukemia
–– Leukemia, Acute Myeloid (AML)
–– Multiple Myeloma
– Solid Tumors
–– Brain Cancer
–– Breast Cancer
–– Colon Cancer
–– Lung Cancer
–– Melanoma
–– Ovarian Cancer
–– Pancreatic Cancer
–– Prostate Cancer
–– Skin cancer
Developmental Disorders
Fertility
Genetic Disorder
Hearing Loss
Heart Disease
– Heart disease associated with Duchenne muscular dystrophy
– Heart failure
– Pulmonary Hypertension
Immune Disease
– Thymic Disorder, 22q11 Deletion/DiGeorge
Incontinence
Infectious Disease
– HIV/AIDS
– Zika virus
Kidney Disease
– Kidney Failure
Metabolic Disorders
– Cystinosis
– Danon Disease
– Diabetes
–– Diabetic Wounds
–– Type 1 diabetes
– Intestinal Disease
– Liver Disease
Neurological Disorders
– Alzheimer's Disease
– Amyotrophic Lateral Sclerosis
– Autism
– Canavan Disease
– Dementia
– Epilepsy
– Huntington's Disease
– Multiple Sclerosis
– Neuropathy
– Parkinson's Disease
– Rett's Syndrome
– Spina Bifida
– Spinal Cord Injury
– Spinal Muscular Atrophy
– Stroke
– Traumatic Brain Injury
Other
Pediatrics
Respiratory Disorders
– Cystic Fibrosis
– Lung Disease, Fibrosis
Skeletal/Smooth Muscle disorders
– Bladder or Urinary Tract Disorder
– Muscular Dystrophy
Skin Disease
– Epidermolysis Bullosa
Toxicity
Trauma
Vascular Disease
Vision Loss
– Age-related macular degeneration
– Corneal Damage
– Retinitis Pigmentosa

Therapeutic Approach
– Biologic
–– Antibody
–– Exosomes based therapy
–– Gene modification
–– Nucleic acid based therapy
–– Protein/peptide therapy
–– Vaccine
– Gene Therapy (All)
–– Gene Therapy, cell free
–– Gene-modified, donor cell therapy
–– Gene-modified, personalized cell therapy
– Small molecule therapy
– Device
– Donor cell therapy
– Personalized cell therapy
– Other Components
Technology
– Assay development
– Diagnostic Test
– Gene editing tools
– Cell delivery or targeting
– Cell imaging & tracking
– Cell processing & handling
– Exploring disease mechanisms
– Exploring stem cell mechanisms
– Immune tolerance/management
– Model system development
– Specific Cell Type Derivation
– Therapeutic target discovery
– Tissue engineering