Active Awards Portfolio Dashboard

It takes a lot of effort to develop a promising stem cell research idea into an effective treatment that can help patients. CIRM funds a pipeline of projects spanning discovery, translation and clinical stage research. Check out our portfolio of active research awards in our interactive dashboard below. For a detailed list of CIRM-funded clinical trials, visit our Clinical Trials Dashboard.

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Disease

Therapeutic or Technology

Disease	Cell Type	Therapeutic or Technology	Institution	Project Objective
Liver Disease	iPS Cell	Cell processing & handling	USC	Tool/Resources/Bottleneck
Huntington's Disease	Embryonic Stem Cell	Gene-modified, donor cell therapy	UC Irvine	Development Candidate, Proof of Concept
Vision Loss	Embryonic Stem Cell	Donor cell therapy	USC	Proof of Concept, Research Insights
Age-related macular degeneration	iPS Cell	Exploring disease mechanisms	UCSD	Research Insights
Thymic Disorder, 22q11 Deletion/DiGeorge	Embryonic Stem Cell, iPS Cell	Donor cell therapy	Stanford	Development Candidate, Proof of Concept
Blood Disorders	Embryonic Stem Cell	Specific Cell Type Derivation	UCLA	Tool/Resources/Bottleneck
Vision Loss	iPS Cell	Cell processing & handling	UCSD	Tool/Resources/Bottleneck
Heart Disease	Directly Reprogrammed Cell	Gene modification	Gladstone	Proof of Concept
Muscular Dystrophy	Embryonic Stem Cell, iPS Cell	Specific Cell Type Derivation	Sanford-Burnham	Research Insights
Hemophilia A	Adult Stem Cell	Gene modification	COH	Development Candidate, Proof of Concept
Heart Disease, Danon Disease	Adult Stem Cell	Gene-modified, personalized cell therapy	UCSD	Development Candidate, Proof of Concept
Skeletal/Smooth Muscle disorders	Embryonic Stem Cell, iPS Cell	Tissue engineering	UCSD	Tool/Resources/Bottleneck
Muscular Dystrophy	iPS Cell	Gene-modified, personalized cell therapy	UCLA	Development Candidate
Parkinson's Disease	iPS Cell	Gene modification	Parkinson's Institute	Development Candidate, Proof of Concept
Skeletal/Smooth Muscle disorders	Adult Stem Cell	Protein/peptide therapy	Stanford	Research Insights
Epilepsy	Embryonic Stem Cell	Donor cell therapy	Neurona Therapeutics	Development Candidate
Cancer	Adult Stem Cell	Gene-modified, donor cell therapy	UCLA	Development Candidate, Proof of Concept
Blood Disorders	Embryonic Stem Cell	Donor cell therapy	UCSF	Research Insights
Neurological Disorders	Embryonic Stem Cell, iPS Cell	Assay development	Scripps	Tool/Resources/Bottleneck
Spinal Cord Injury	Embryonic Stem Cell, iPS Cell	Donor cell therapy	UC Berkeley	Proof of Concept
Blood Cancer, Ovarian Cancer	Embryonic Stem Cell, iPS Cell	Donor cell therapy	UCSD	Development Candidate
B cell cancers, Leukemia	Cancer Stem Cell	Antibody	COH	Development Candidate, Proof of Concept
Type 1 diabetes	Embryonic Stem Cell	Gene-modified, donor cell therapy	UCSD	Development Candidate, Proof of Concept
Dementia	iPS Cell	Donor cell therapy	Gladstone	Development Candidate, Proof of Concept
Heart Disease	Embryonic Stem Cell	Donor cell therapy	UCLA	Proof of Concept
Bone or Cartilage Disease	Adult Stem Cell	Tissue engineering	Stanford	Proof of Concept, Research Insights
Autism	Adult Stem Cell	Gene-modified, donor cell therapy	UC Davis	Development Candidate, Proof of Concept
Blood Disorders, Blood Cancer	Adult Stem Cell	Small molecule therapy	UCLA	Development Candidate
Parkinson's Disease	iPS Cell	Cell processing & handling	Scaled Biolabs Inc.	Development Candidate
Respiratory Disorders	Directly Reprogrammed Cell	Model system development	UCSF	Research Insights
Type 1 diabetes	Embryonic Stem Cell	Gene-modified, donor cell therapy	ViaCyte	Development Candidate
Type 1 diabetes	Embryonic Stem Cell	Gene-modified, donor cell therapy	Salk	Development Candidate, Proof of Concept
Blood Disorders	Adult Stem Cell	Cell processing & handling	UCSF	Tool/Resources/Bottleneck
HIV/AIDS	Adult Stem Cell	Gene-modified, personalized cell therapy	CIT	Proof of Concept
Diabetes	Embryonic Stem Cell	Donor cell therapy	UCSF	Development Candidate, Proof of Concept
Liver Disease	Directly Reprogrammed Cell	Gene modification	UCSF	Development Candidate
Other	Adult Stem Cell	Cell imaging & tracking	Stanford	Tool/Resources/Bottleneck
Skeletal/Smooth Muscle disorders	Adult Stem Cell	Small molecule therapy	Stanford	Development Candidate
Vision Loss	iPS Cell	Small molecule therapy	UCSD	Development Candidate, Proof of Concept
Amyotrophic Lateral Sclerosis, Spinal Cord Injury, Spinal Muscular Atrophy	Embryonic Stem Cell	Model system development	UCLA	Tool/Resources/Bottleneck
Cystic Fibrosis	Adult Stem Cell	Gene-modified, personalized cell therapy	Stanford	Development Candidate
Heart Disease	iPS Cell	Model system development	UC Berkeley	Proof of Concept
Vascular Disease	Adult Stem Cell	Personalized cell therapy	UC Davis	Proof of Concept
Spinal Cord Injury	Embryonic Stem Cell	Donor cell therapy	UCSD	Development Candidate
Liver Disease	iPS Cell	Gene-modified, donor cell therapy	CHLA	Development Candidate, Proof of Concept
Neurological Disorders, Zika virus	iPS Cell	Small molecule therapy	UCSD	Development Candidate
Colon Cancer	Cancer Stem Cell	Small molecule therapy	COH	Development Candidate, Proof of Concept
Other	Embryonic Stem Cell, iPS Cell	Exploring stem cell mechanisms	UCSD	Research Insights
Liver Disease	Embryonic Stem Cell	Donor cell therapy	Stanford	Development Candidate, Proof of Concept
Autism	iPS Cell	Small molecule therapy	Scripps	Development Candidate, Proof of Concept

California's Stem Cell Agency

California Institute for Regenerative Medicine

Active Awards Portfolio Dashboard

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Pages

Aging
Arthritis
Blood Disorders
– Alpha Thalassemia Major
– Anemia
– Beta Thalassemia
– Bone Marrow Transplant and Viral Infection
– Hemophilia A
– Leukocyte Adhesion Deficiency
– Severe Combined Immunodeficiency, Adenosine deaminase-deficient (ADA-SCID)
– Severe Combined Immunodeficiency, Artemis deficient (ART-SCID)
– Severe Combined Immunodeficiency, X-linked (X-SCID)
– Sickle Cell Disease
– X-linked Chronic Granulomatous Disease
Bone or Cartilage Disease
– Intervertebral disc degeneration
– Osteoarthritis
– Osteonecrosis
Cancer
– Blood Cancer
–– Acute Myeloid Leukemia
–– B cell cancers
–– HIV-related Lymphoma
–– Leukemia
–– Leukemia, Acute Myeloid (AML)
–– Multiple Myeloma
– Solid Tumors
–– Brain Cancer
–– Breast Cancer
–– Colon Cancer
–– Lung Cancer
–– Melanoma
–– Ovarian Cancer
–– Pancreatic Cancer
–– Prostate Cancer
–– Sarcoma
–– Skin cancer
Developmental Disorders
Fertility
Genetic Disorder
Hearing Loss
Heart Disease
– Heart disease associated with Duchenne muscular dystrophy
– Heart failure
– Pulmonary Hypertension
Immune Disease
– Thymic Disorder, 22q11 Deletion/DiGeorge
Incontinence
Infectious Disease
– HIV/AIDS
– Zika virus
Kidney Disease
– Kidney Failure
Metabolic Disorders
– Cystinosis
– Danon Disease
– Diabetes
–– Diabetic Wounds
–– Type 1 diabetes
– Intestinal Disease
– Liver Disease
Neurological Disorders
– Alzheimer's Disease
– Amyotrophic Lateral Sclerosis
– Autism
– Canavan Disease
– Dementia
– Epilepsy
– Huntington's Disease
– Multiple Sclerosis
– Neuropathy
– Parkinson's Disease
– Rett's Syndrome
– Spina Bifida
– Spinal Cord Injury
– Spinal Muscular Atrophy
– Stroke
– Traumatic Brain Injury
Other
Pediatrics
Respiratory Disorders
– Cystic Fibrosis
– Lung Disease, Fibrosis
Skeletal/Smooth Muscle disorders
– Bladder or Urinary Tract Disorder
– Muscular Dystrophy
Skin Disease
– Epidermolysis Bullosa
Toxicity
Trauma
Vascular Disease
Vision Loss
– Age-related macular degeneration
– Corneal Damage
– Retinitis Pigmentosa

Therapeutic Approach
– Biologic
–– Antibody
–– Exosomes based therapy
–– Gene modification
–– Nucleic acid based therapy
–– Protein/peptide therapy
–– Vaccine
– Gene Therapy (All)
–– Gene Therapy, cell free
–– Gene-modified, donor cell therapy
–– Gene-modified, personalized cell therapy
– Small molecule therapy
– Device
– Donor cell therapy
– Personalized cell therapy
– Other Components
Technology
– Assay development
– Cell Line Generation-Resource
– Diagnostic Test
– Gene editing tools
– Cell delivery or targeting
– Cell imaging & tracking
– Cell processing & handling
– Exploring disease mechanisms
– Exploring stem cell mechanisms
– Immune tolerance/management
– Model system development
– Specific Cell Type Derivation
– Therapeutic target discovery
– Tissue engineering